Science
An AI app claims it can detect sexually transmitted infections. Doctors say it's a disaster
Late last month, the San Francisco-based startup HeHealth announced the launch of Calmara.ai, a cheerful, emoji-laden website the company describes as “your tech savvy BFF for STI checks.”
The concept is simple. A user concerned about their partner’s sexual health status just snaps a photo (with consent, the service notes) of the partner’s penis (the only part of the human body the software is trained to recognize) and uploads it to Calmara.
In seconds, the site scans the image and returns one of two messages: “Clear! No visible signs of STIs spotted for now” or “Hold!!! We spotted something sus.”
Calmara describes the free service as “the next best thing to a lab test for a quick check,” powered by artificial intelligence with “up to 94.4% accuracy rate” (though finer print on the site clarifies its actual performance is “65% to 96% across various conditions.”)
Since its debut, privacy and public health experts have pointed with alarm to a number of significant oversights in Calmara’s design, such as its flimsy consent verification, its potential to receive child pornography and an over-reliance on images to screen for conditions that are often invisible.
But even as a rudimentary screening tool for visual signs of sexually transmitted infections in one specific human organ, tests of Calmara showed the service to be inaccurate, unreliable and prone to the same kind of stigmatizing information its parent company says it wants to combat.
A Los Angeles Times reporter uploaded to Calmara a broad range of penis images taken from the Centers for Disease Control and Prevention’s Public Health Image Library, the STD Center NY and the Royal Australian College of General Practitioners.
Calmara issued a “Hold!!!” to multiple images of penile lesions and bumps caused by sexually transmitted conditions, including syphilis, chlamydia, herpes and human papillomavirus, the virus that causes genital warts.
Screenshots, with genitals obscured by illustrations, show that Calmara gave a “Clear!” to a photo from the CDC of a severe case of syphilis, left, uploaded by The Times; the app said “Hold!!!” on a photo, from the Royal Australian College of General Practitioners, of a penis with no STIs.
(Screenshots via Calmara.ai; photo illustration by Los Angeles Times)
But the site failed to recognize some textbook images of sexually transmitted infections, including a chancroid ulcer and a case of syphilis so pronounced the foreskin was no longer able to retract.
Calmara’s AI frequently inaccurately identified naturally occurring, non-pathological penile bumps as signs of infection, flagging multiple images of disease-free organs as “something sus.”
It also struggled to distinguish between inanimate objects and human genitals, issuing a cheery “Clear!” to images of both a novelty penis-shaped vase and a penis-shaped cake.
“There are so many things wrong with this app that I don’t even know where to begin,” said Dr. Ina Park, a UC San Francisco professor who serves as a medical consultant for the CDC’s Division of STD Prevention. “With any tests you’re doing for STIs, there is always the possibility of false negatives and false positives. The issue with this app is that it appears to be rife with both.”
Dr. Jeffrey Klausner, an infectious-disease specialist at USC’s Keck School of Medicine and a scientific adviser to HeHealth, acknowledged that Calmara “can’t be promoted as a screening test.”
“To get screened for STIs, you’ve got to get a blood test. You have to get a urine test,” he said. “Having someone look at a penis, or having a digital assistant look at a penis, is not going to be able to detect HIV, syphilis, chlamydia, gonorrhea. Even most cases of herpes are asymptomatic.”
Calmara, he said, is “a very different thing” from HeHealth’s signature product, a paid service that scans images a user submits of his own penis and flags anything that merits follow-up with a healthcare provider.
Klausner did not respond to requests for additional comment about the app’s accuracy.
Both HeHealth and Calmara use the same underlying AI, though the two sites “may have differences at identifying issues of concern,” co-founder and CEO Dr. Yudara Kularathne said.
“Powered by patented HeHealth wizardry (think an AI so sharp you’d think it aced its SATs), our AI’s been battle-tested by over 40,000 users,” Calmara’s website reads, before noting that its accuracy ranges from 65% to 96%.
“It’s great that they disclose that, but 65% is terrible,” said Dr. Sean Young, a UCI professor of emergency medicine and executive director of the University of California Institute for Prediction Technology. “From a public health perspective, if you’re giving people 65% accuracy, why even tell anyone anything? That’s potentially more harmful than beneficial.”
Kularathne said the accuracy range “highlights the complexity of detecting STIs and other visible conditions on the penis, each with its unique characteristics and challenges.” He added: “It’s important to understand that this is just the starting point for Calmara. As we refine our AI with more insights, we expect these figures to improve.”
On HeHealth’s website, Kularathne says he was inspired to start the company after a friend became suicidal after “an STI scare magnified by online misinformation.”
“Numerous physiological conditions are often mistaken for STIs, and our technology can provide peace of mind in these situations,” Kularathne posted Tuesday on LinkedIn. “Our technology aims to bring clarity to young people, especially Gen Z.”
Calmara’s AI also mistook some physiological conditions for STIs.
The Times uploaded a number of images onto the site that were posted on a medical website as examples of non-communicable, non-pathological anatomical variations in the human penis that are sometimes confused with STIs, including skin tags, visible sebaceous glands and enlarged capillaries.
Calmara identified each one as “something sus.”
Such inaccurate information could have exactly the opposite effect on young users than the “clarity” its founders intend, said Dr. Joni Roberts, an assistant professor at Cal Poly San Luis Obispo who runs the campus’s Sexual and Reproductive Health Lab.
“If I am 18 years old, I take a picture of something that is a normal occurrence as part of the human body, [and] I get this that says that it’s ‘sus’? Now I’m stressing out,” Roberts said.
“We already know that mental health [issues are] extremely high in this population. Social media has run havoc on people’s self image, worth, depression, et cetera,” she said. “Saying something is ‘sus’ without providing any information is problematic.”
Kularathne defended the site’s choice of language. “The phrase ‘something sus’ is deliberately chosen to indicate ambiguity and suggest the need for further investigation,” he wrote in an email. “It’s a prompt for users to seek professional advice, fostering a culture of caution and responsibility.”
Still, “the misidentification of healthy anatomy as ‘something sus’ if that happens, is indeed not the outcome we aim for,” he wrote.
Users whose photos are issued a “Hold” notice are directed to HeHealth where, for a fee, they can submit additional photos of their penis for further scanning.
Those who get a “Clear” are told “No visible signs of STIs spotted for now . . . But this isn’t an all-clear for STIs,” noting, correctly, that many sexually transmitted conditions are asymptomatic and invisible. Users who click through Calmara’s FAQs will also find a disclaimer that a “Clear!” notification “doesn’t mean you can skimp on further checks.”
Young raised concerns that some people might use the app to make immediate decisions about their sexual health.
“There’s more ethical obligations to be able to be transparent and clear about your data and practices, and to not use the typical startup approaches that a lot of other companies will use in non-health spaces,” he said.
In its current form, he said, Calmara “has the potential to further stigmatize not only STIs, but to further stigmatize digital health by giving inaccurate diagnoses and having people make claims that every digital health tool or app is just a big sham.”
HeHealth.ai has raised about $1.1 million since its founding in 2019, co-founder Mei-Ling Lu said. The company is currently seeking another $1.5 million from investors, according to PitchBook.
Medical experts interviewed for this article said that technology can and should be used to reduce barriers to sexual healthcare. Providers including Planned Parenthood and the Mayo Clinic are using AI tools to share vetted information with their patients, said Mara Decker, a UC San Francisco epidemiologist who studies sexual health education and digital technology.
But when it comes to Calmara’s approach, “I basically can see only negatives and no benefits,” Decker said. “They could just as easily replace their app with a sign that says, ‘If you have a rash or noticeable sore, go get tested.’”
Science
Diablo Canyon clears last California permit hurdle to keep running
Central Coast Water authorities approved waste discharge permits for Diablo Canyon nuclear plant Thursday, making it nearly certain it will remain running through 2030, and potentially through 2045.
The Pacific Gas & Electric-owned plant was originally supposed to shut down in 2025, but lawmakers extended that deadline by five years in 2022, fearing power shortages if a plant that provides about 9 percent the state’s electricity were to shut off.
In December, Diablo Canyon received a key permit from the California Coastal Commission through an agreement that involved PG&E giving up about 12,000 acres of nearby land for conservation in exchange for the loss of marine life caused by the plant’s operations.
Today’s 6-0 vote by the Central Coast Regional Water Board approved PG&E’s plans to limit discharges of pollutants into the water and continue to run its “once-through cooling system.” The cooling technology flushes ocean water through the plant to absorb heat and discharges it, killing what the Coastal Commission estimated to be two billion fish each year.
The board also granted the plant a certification under the Clean Water Act, the last state regulatory hurdle the facility needed to clear before the federal Nuclear Regulatory Commission (NRC) is allowed to renew its permit through 2045.
The new regional water board permit made several changes since the last one was issued in 1990. One was a first-time limit on the chemical tributyltin-10, a toxic, internationally-banned compound added to paint to prevent organisms from growing on ship hulls.
Additional changes stemmed from a 2025 Supreme Court ruling that said if pollutant permits like this one impose specific water quality requirements, they must also specify how to meet them.
The plant’s biggest water quality impact is the heated water it discharges into the ocean, and that part of the permit remains unchanged. Radioactive waste from the plant is regulated not by the state but by the NRC.
California state law only allows the plant to remain open to 2030, but some lawmakers and regulators have already expressed interest in another extension given growing electricity demand and the plant’s role in providing carbon-free power to the grid.
Some board members raised concerns about granting a certification that would allow the NRC to reauthorize the plant’s permits through 2045.
“There’s every reason to think the California entities responsible for making the decision about continuing operation, namely the California [Independent System Operator] and the Energy Commission, all of them are sort of leaning toward continuing to operate this facility,” said boardmember Dominic Roques. “I’d like us to be consistent with state law at least, and imply that we are consistent with ending operation at five years.”
Other board members noted that regulators could revisit the permits in five years or sooner if state and federal laws changes, and the board ultimately approved the permit.
Science
Deadly bird flu found in California elephant seals for the first time
The H5N1 bird flu virus that devastated South American elephant seal populations has been confirmed in seals at California’s Año Nuevo State Park, researchers from UC Davis and UC Santa Cruz announced Wednesday.
The virus has ravaged wild, commercial and domestic animals across the globe and was found last week in seven weaned pups. The confirmation came from the U.S. Department of Agriculture’s National Veterinary Services Laboratory in Ames, Iowa.
“This is exceptionally rapid detection of an outbreak in free-ranging marine mammals,” said Professor Christine Johnson, director of the Institute for Pandemic Insights at UC Davis’ Weill School of Veterinary Medicine. “We have most likely identified the very first cases here because of coordinated teams that have been on high alert with active surveillance for this disease for some time.”
Since last week, when researchers began noticing neurological and respoiratory signs of the disease in some animals, 30 seals have died, said Roxanne Beltran, a professor of ecology and evolutionary biology at UC Santa Cruz. Twenty-nine were weaned pups and the other was an adult male. The team has so far confirmed the virus in only seven of the dead pups.
Infected animals often have tremors convulsions, seizures and muscle weakness, Johnson said.
Beltran said teams from UC Santa Cruz, UC Davis and California State Parks monitor the animals 260 days of the year, “including every day from December 15 to March 1” when the animals typically come ashore to breed, give birth and nurse.
The concerning behavior and deaths were first noticed Feb. 19.
“This is one of the most well-studied elephant seal colonies on the planet,” she said. “We know the seals so well that it’s very obvious to us when something is abnormal. And so my team was out that morning and we observed abnormal behaviors in seals and increased mortality that we had not seen the day before in those exact same locations. So we were very confident that we caught the beginning of this outbreak.”
In late 2022, the virus decimated southern elephant seal populations in South America and several sub-Antarctic Islands. At some colonies in Argentina, 97% of pups died, while on South Georgia Island, researchers reported a 47% decline in breeding females between 2022 and 2024. Researchers believe tens of thousands of animals died.
More than 30,000 sea lions in Peru and Chile died between 2022 and 2024. In Argentina, roughly 1,300 sea lions and fur seals perished.
At the time, researchers were not sure why northern Pacific populations were not infected, but suspected previous or milder strains of the virus conferred some immunity.
The virus is better known in the U.S. for sweeping through the nation’s dairy herds, where it infected dozens of dairy workers, millions of cows and thousands of wild, feral and domestic mammals. It’s also been found in wild birds and killed millions of commercial chickens, geese and ducks.
Two Americans have died from the virus since 2024, and 71 have been infected. The vast majority were dairy or commercial poultry workers. One death was that of a Louisiana man who had underlying conditions and was believed to have been exposed via backyard poultry or wild birds.
Scientists at UC Santa Cruz and UC Davis increased their surveillance of the elephant seals in Año Nuevo in recent years. The catastrophic effect of the disease prompted worry that it would spread to California elephant seals, said Beltran, whose lab leads UC Santa Cruz’s northern elephant seal research program at Año Nuevo.
Johnson, the UC Davis researcher, said the team has been working with stranding networks across the Pacific region for several years — sampling the tissue of birds, elephant seals and other marine mammals. They have not seen the virus in other California marine mammals. Two previous outbreaks of bird flu in U.S. marine mammals occurred in Maine in 2022 and Washington in 2023, affecting gray and harbor seals.
The virus in the animals has not yet been fully sequenced, so it’s unclear how the animals were exposed.
“We think the transmission is actually from dead and dying sea birds” living among the sea lions, Johnson said. “But we’ll certainly be investigating if there’s any mammal-to-mammal transmission.”
Genetic sequencing from southern elephant seal populations in Argentina suggested that version of the virus had acquired mutations that allowed it to pass between mammals.
The H5N1 virus was first detected in geese in China in 1996. Since then it has spread across the globe, reaching North America in 2021. The only continent where it has not been detected is Oceania.
Año Nuevo State Park, just north of Santa Cruz, is home to a colony of some 5,000 elephant seals during the winter breeding season. About 1,350 seals were on the beach when the outbreak began. Other large California colonies are located at Piedras Blancas and Point Reyes National Sea Shore. Most of those animals — roughly 900 — are weaned pups.
It’s “important to keep this in context. So far, avian influenza has affected only a small proportion of the weaned at this time, and there are still thousands of apparently healthy animals in the population,” Beltran said in a press conference.
Public access to the park has been closed and guided elephant seal tours canceled.
Health and wildlife officials urge beachgoers to keep a safe distance from wildlife and keep dogs leashed because the virus is contagious.
Science
When slowing down can save a life: Training L.A. law enforcement to understand autism
Kate Movius moved among a roomful of Los Angeles County sheriff’s deputies, passing out a pop trivia quiz and paper prism glasses.
She told them to put on the vision-distorting glasses, and to write with their nondominant hand. As they filled out the tests, Movius moved about the City of Industry classroom pounding abruptly on tables. Then came the cowbell. An aide flashed the overhead lights on and off at random. The goal was to help the deputies understand the feeling of sensory overwhelm, which many autistic people experience when incoming stimulation exceeds their capacity to process.
“So what can you do to assist somebody, or de-escalate somebody, or get information from someone who suffers from a sensory disorder?” Movius asked the rattled crowd afterward. “We can minimize sensory input. … That might be the difference between them being able to stay calm and them taking off.”
Movius, founder of the consultancy Autism Interaction Solutions, is one of a growing number of people around the U.S. working to teach law enforcement agencies to recognize autistic behaviors and ensure that encounters between neurodevelopmentally disabled people and law enforcement end safely.
She and City of Industry Mayor Cory Moss later passed out bags filled with tools donated by the city to aid interactions: a pair of noise-damping headphones to decrease auditory input, a whiteboard, a set of communication cards with words and images to point to, fidget toys to calm and distract.
“The thing about autistic behavior when it comes to law enforcement is a lot of it may look suspicious, and a lot of it may feel very disrespectful,” said Movius, who is also the parent of an autistic 25-year-old man. Responding officers, she said, “are not coming in thinking, ‘Could this be a developmentally disabled person?’ I would love for them to have that in the back of their minds.”
A sheriff’s deputy reads a pamphlet on autism during the training program.
(Genaro Molina / Los Angeles Times)
Autism spectrum disorder is a developmental condition that manifests differently in nearly every person who has it. Symptoms cluster around difficulties in communication, social interaction and sensory processing.
An autistic person stopped by police might hold the officer’s gaze intensely or not look at them at all. They may repeat a phrase from a movie, repeat the officer’s question or temporarily lose their ability to speak. They might flee.
All are common involuntary responses for an autistic person in a stressful situation, which a sudden encounter with law enforcement almost invariably is. To someone unfamiliar with the condition, all could be mistaken for intoxication, defiance or guilt.
Autism rates in the U.S. have increased nearly fivefold since the Centers for Disease Control began tracking diagnoses in 2000, a rise experts attribute to broadening diagnostic criteria and better efforts to identify children who have the condition.
The CDC now estimates that 1 in 31 U.S. 8-year-olds is autistic. In California, the rate is closer to 1 in 22 children.
As diverse as the autistic population is, people across the spectrum are more likely to be stopped by law enforcement than neurotypical peers.
About 15% of all people in the U.S. ages 18 to 24 have been stopped by police at some point in their lives, according to federal data. While the government doesn’t track encounters for disabled people specifically, a separate study found that 20% of autistic people ages 21 to 25 have been stopped, often after a report or officer observation of a person behaving unusually.
Some of these encounters have ended in tragedy.
In 2021, Los Angeles County sheriff’s deputies shot and permanently paralyzed a deaf autistic man after family members called 911 for help getting him to a hospital.
Isaias Cervantes, 25, had become distressed about a shopping trip and started pushing his mother, his family’s attorney said at the time. He resisted as two deputies attempted to handcuff him and one of the deputies shot him, according to a county report.
In 2024, Ryan Gainer’s family called 911 for support when the 15-year-old became agitated. Responding San Bernardino County sheriff‘s deputies shot and killed him outside his Apple Valley home.
Last year, police in Pocatello, Idaho, shot Victor Perez, 17, through a chain-link fence after the nonspeaking teenager did not heed their shouted commands. He died from his injuries in April.
Sheriff’s deputies take a trivia quiz using their non-writing hands, while wearing vision-distorting glasses, as Kate Movius, standing left, and Industry Mayor Cory Moss, right, ring cowbells. The idea was to help them understand the sensory overwhelm some autistic people experience.
(Genaro Molina / Los Angeles Times)
As early as 2001, the FBI published a bulletin on police officers’ need to adjust their approach when interacting with autistic people.
“Officers should not interpret an autistic individual’s failure to respond to orders or questions as a lack of cooperation or as a reason for increased force,” the bulletin stated. “They also need to recognize that individuals with autism often confess to crimes that they did not commit or may respond to the last choice in a sequence presented in a question.”
But a review of multiple studies last year by Chapman University researchers found that while up to 60% of officers have been on a call involving an autistic person, only 5% to 40% had received any training on autism.
In response, universities, nonprofits and private consultants across the U.S. have developed curricula for law enforcement on how to recognize autistic behaviors and adapt accordingly.
The primary goal, Movius told deputies at November’s training session, is to slow interactions down to the greatest extent possible. Many autistic people require additional time to process auditory input and verbal responses, particularly in unfamiliar circumstances.
If at all possible, Movius said, wait 20 seconds for a response after asking a question. It may feel unnaturally long, she acknowledged. But every additional question or instruction fired in that time — what’s your name? Did you hear me? Look at me. What’s your name? — just decreases the likelihood that a person struggling to process will be able to respond at all.
Moss’ son, Brayden, then 17, was one of several teenagers and young adults with autism who spoke or wrote statements to be read to the deputies. The diversity of their speech patterns and physical mannerisms showed the breadth of the spectrum. Some were fluently verbal, while others communicated through signs and notes.
“This population is so diverse. It is so complicated. But if there’s anything that we can show [deputies] in here that will make them stop and think, ‘Hey, what if this is autism?’ … it is saving lives,” Moss said.
Mayor Cory Moss, left, and Kate Movius hug at the end of the training program last November. Movius started Autism Interaction Solutions after her son was born with profound autism.
(Genaro Molina / Los Angeles Times)
Some disability advocates cautioned that it takes more than isolated training sessions to ensure encounters end safely.
Judy Mark, co-founder and president of the nonprofit Disability Voices United, says she trained thousands of officers on safe autism interactions but stopped after Cervantes’ shooting. She now urges families concerned about an autistic child’s safety to call an ambulance rather than law enforcement.
“I have significant concern about these training sessions,” Mark said. “People get comfort from it, and the Sheriff’s Department can check the box.”
While not a panacea, supporters argue that a brief course is better than no preparation at all. Some years ago, Movius received a letter from a man whose profoundly autistic son slipped away as the family loaded their car at the beach. He opened the unlocked door of a police vehicle, climbed into the back and began to flail in distress.
Though surprised, the officer seated at the wheel de-escalated the situation and helped the young man find his family, the father wrote to Movius. He had just been to her training.
-
World2 days agoExclusive: DeepSeek withholds latest AI model from US chipmakers including Nvidia, sources say
-
Massachusetts2 days agoMother and daughter injured in Taunton house explosion
-
Montana1 week ago2026 MHSA Montana Wrestling State Championship Brackets And Results – FloWrestling
-
Oklahoma1 week agoWildfires rage in Oklahoma as thousands urged to evacuate a small city
-
Louisiana4 days agoWildfire near Gum Swamp Road in Livingston Parish now under control; more than 200 acres burned
-
Technology6 days agoYouTube TV billing scam emails are hitting inboxes
-
Denver, CO2 days ago10 acres charred, 5 injured in Thornton grass fire, evacuation orders lifted
-
Technology6 days agoStellantis is in a crisis of its own making