Health
'Western diet' blamed for growing risk of GI cancers among young adults
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The rates of gastrointestinal (GI) cancers are rising among young adults, with a new peer-reviewed study pointing to the American diet and lifestyle as the primary culprits.
The rising risk in younger generations may be linked more to environmental factors than genetics, stated the report, which was recently published in the British Journal of Surgery.
“Some shared risk factors for early-onset (EO) GI cancer include obesity, sedentary lifestyle, excessive alcohol consumption and smoking,” lead researcher Sara Char, M.D., at the Dana Farber Cancer Institute in Boston, told Fox News Digital.
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The study notes that recent generations are more likely to adopt a “Western-pattern diet” and a “sedentary lifestyle.”
Colorectal is the most common type of early-onset GI cancer, but pancreatic, esophageal, gastric, biliary, appendiceal and neuroendocrine cancers are also rising in adults under 50, Char noted.
The report notes that recent generations are more likely to adopt a “Western-pattern diet” and a sedentary lifestyle. (iStock)
Adults born in 1990 have twice the risk of colon cancer and four times the risk of rectal cancer compared to those born in 1950, according to a previous study published in the Journal of the National Cancer Institute.
How diet impacts risk
Paul Oberstein, M.D., director of the Gastrointestinal Medical Oncology Program at NYU Langone’s Perlmutter Cancer Center, told Fox News Digital that a person’s diet does indeed impact the risk of colon cancer.
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“It is reported from previous studies that when someone has a higher amount of foods typical of a Western diet, they have a higher risk of colon cancer,” said Oberstein, who was not involved in the research.
A “Western diet” typically includes a higher intake of red and processed meats, processed and added sugars, and highly processed and refined grains, according to the oncologist.
Adults born in 1990 have twice the risk of colon cancer and four times the risk of rectal cancer compared to those born in 1950. (iStock)
Processed deli meats, sugary drinks and processed grain snacks are also commonly associated with this type of diet.
Research and recommendations
While the incidence of colon cancer in this group overall remains low, Oberstein recommends investing in more research to explore which factors are causing the increase.
“We need to conduct more research on whether diet, vitamin supplements, alcohol or other things we ingest or use are contributing to this increase,” he said.
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The expert also emphasized the importance of following the recommended colon cancer screening guidelines, which begin at 45 years old for most people, and seeking medical attention if any symptoms appear.
“We need to conduct more research on whether diet, vitamin supplements, alcohol or other things we ingest or use are contributing to this increase,” an oncologist said. (iStock)
Common warning signs include changes in bowel habits, blood in the stool, unexplained back or abdominal pain, or unintentional weight loss, all of which warrant speaking to a doctor for an “urgent evaluation,” according to Char.
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The researcher added that younger individuals can take preventative measures such as not smoking, avoiding excessive alcohol, limiting red meat consumption, staying physically active and maintaining a healthy body weight.
Health
New ways to prevent flu revealed in ‘accidental’ lab breakthrough, study finds
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An accidental lab discovery has opened the door to entirely new ways of preventing the flu.
While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells, SWNS reported.
By targeting the specific molecules the viruses rely on, scientists found that they could block them from entering new cells and halt their replication altogether.
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Researchers say these “fundamental insights” into seasonal influenza highlight a clear path toward developing better preventive medications.
“The hope is that fundamental, curiosity-based research like this helps to pave the way for novel strategies to treat and prevent influenza infections,” principal investigator Dr. Emily Bruce, from the University of Vermont’s Larner College of Medicine, said in the SWNS report.
While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells. (iStock)
While several flu strains cause illness, H1N1 and H3N2 influenza A viruses are the most common. However, current flu tests cannot differentiate between them, and clinical treatments are identical for both.
Although vaccines and antivirals are available, Bruce noted a “dire” need for better medications to stop the virus from spreading cell to xxcell.
“You don’t get sick when a virus is in one cell,” he noted. “You get sick because a virus replicates itself and goes into many more cells.”
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The study, which was published in The Journal of Virology, originally aimed to map how viral RNA segments are transported within cells to create new viral particles.
The team used H1N1 and H3N2 viruses isolated from the nasal passages of positive patients in 2022.
Clinical treatments remain identical for both primary strains of the flu virus. (iStock)
During the investigation, the team unexpectedly stumbled upon a cellular pathway that blocked the virus from entering lung cells, SWNS reported.
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The data revealed that when a specific human protein called Rab11B was depleted, H3N2 viruses failed to enter human lung cells. H1N1 viruses were completely unaffected.
Using reverse genetics, the team mapped this defect and uncovered a brand-new, H3N2-specific role for Rab11B during viral entry.
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This discovery challenged the scientific assumption that all flu viruses enter cells the same way.
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“Viruses are like pirates from different countries hijacking someone’s ship,” Bruce said. “Different viruses, like different types of pirates, use different methods to get onboard.”
This discovery challenged the scientific assumption that all flu viruses enter cells the same way. (iStock)
“We had previously thought that all flu viruses used the same way to get into a cell, but we discovered that this is not true,” she went on. “H1N1 and H3N2 need different proteins to get in, and if you get rid of the right protein, a specific virus can’t get in.”
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While these findings identify a critical cellular pathway for viral entry, the study was conducted using isolated cells, the researchers acknowledged.
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Further research is needed to determine whether blocking the protein is safe and effective within a live, complex human respiratory system.
Bruce and the team hope to conduct further research to determine whether this Rab11B-dependency is a fundamental property of H3N2, or if it’s a trait unique to currently circulating flu strains.
Health
One extra serving of processed meat a day linked to higher cancer risk
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Eating processed meat like ham, sausage and bacon may be linked to a higher risk of certain types of cancer, according to new research.
While health organizations have already confirmed that processed meat can contribute to colon cancer, this study looked closer at cancers in the upper digestive tract, where the link has historically been less clear.
To understand these connections, researchers from the European Prospective Investigation into Cancer and Nutrition (EPIC), one of the world’s largest long-term nutrition and cancer cohorts, tracked the health and diets of 450,112 people across Europe for an average of 14 years.
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The study group included 131,426 men and 318,686 women, according to the study’s press release.
During the follow-up period, 876 people developed stomach cancer and 215 people developed esophageal adenocarcinoma, which is cancer of the tube connecting the mouth to the stomach.
For female participants, eating both processed meat and white meat was linked to an increased risk of developing the disease. (iStock)
Researchers tracked where the stomach cancers grew, separating them into the upper part of the stomach near the throat and the lower part of the stomach.
The researchers also sorted the tumors into two categories based on how the cancer cells appeared under a microscope: intestinal, which forms more organized structures, and diffuse, in which the cells are more scattered throughout the tissue.
BACTERIA IN YOUR MOUTH MAY TRAVEL TO THE GUT AND TRIGGER STOMACH CANCER, RESEARCH FINDS
After adjusting for other lifestyle factors, the researchers found that for every extra 30 grams of processed meat a person ate per day, their overall risk of stomach cancer went up by 9%. Eating that same extra 30 grams a day was also linked to a 13% higher risk of esophageal adenocarcinoma.
A standard single slice of regular deli-sliced ham or lunch meat averages around 28 grams, according to USDA data and nutritional tracking databases.
An extra 20 grams of white meat, such as chicken and turkey, was linked to a 12% higher risk of cancer in the main body of the stomach. (iStock)
An extra 20 grams of white meat, such as chicken or turkey, was linked to a 12% higher risk of cancer in the main body of the stomach, the researchers noted.
The study also revealed differences between men and women. For male participants, only processed meat showed a clear, statistically significant link to a higher risk of stomach cancer. For female participants, however, eating both processed meat and white meat was linked to an increased risk.
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These findings align with global health benchmarks, particularly those established by the World Health Organization’s International Agency for Research on Cancer.
The agency has long classified processed meat as a known human carcinogen, primarily due to its strong, well-documented links to colorectal cancer.
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However, health organizations have also consistently pointed to a potential, yet less definitive, relationship between these meats and cancers of the stomach.
Eating 30 grams of processed meat a day, or the equivalent to one slice of ham, was linked to a 13% higher risk of esophageal adenocarcinoma. (iStock)
Further scientific investigation is needed to confirm the findings and to account for other underlying risk factors, such as certain stomach infections, which could interact with dietary habits.
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A key limitation of the study is its reliance on self-reported diets, which can sometimes lead to inaccuracies in how participants recall their meat consumption over time, the researchers noted.
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The findings were published in the International Journal of Cancer.
Fox News Digital reached out to the researchers requesting comment.
Health
The Surprising Hormone That Could Make Menopause Weight Loss Easier
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