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Chronic lack of sleep may negatively affect our immune cells, raising certain health risks: New study

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Chronic lack of sleep may negatively affect our immune cells, raising certain health risks: New study

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Dropping an hour-and-a-half of sleep every evening on a constant foundation could result in inflammatory problems and heart problems, in line with a brand new examine from the Icahn Faculty of Medication at Mount Sinai in New York Metropolis.

The examine — revealed within the Journal of Experimental Medication on Wed., Sept. 21, 2022 — discovered {that a} continual lack of sleep might have an effect on an individual’s immune cells and contribute to irritation within the physique. 

“A rise of irritation makes you inclined to an entire bunch of issues, particularly cardiovascular ailments,” co-lead investigator Cameron McAlpine, Ph.D., assistant professor of drugs (cardiology) at Icahn Mount Sinai, advised Fox Information Digital in an interview. 

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McAlpine is without doubt one of the researchers who participated within the new examine. 

Lead writer Filip Swirski, Ph.D., director of the Cardiovascular Analysis Institute at Icahn Mount Sinai, mentioned in a information launch, “This work emphasizes the significance of adults constantly sleeping seven to eight hours a day to assist stop irritation and illness, particularly for these with underlying medical circumstances.” 

Adults must sleep seven to eight hours an evening, mentioned the lead writer of a brand new examine, “to assist stop irritation and illness, particularly for these with underlying medical circumstances.”
(iStock)

The researchers mentioned the examine begins to establish the mechanisms within the physique that hyperlink sleep and immunological well being over the long run. 

The examine revealed that in people and mice, disturbed sleep can affect the cell programming and charge of manufacturing of the immune cells; this will then trigger the immune cells to lose their effectiveness in defending towards illness.

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SLEEPING WITH LIGHTS OFF AND CLOSED BLINDS MAY PROTECT YOUR HEALTH: STUDY

It could actually additionally have an effect on the speed of manufacturing of those cells and probably make infections worse. 

“One other key remark [is that] that sleep reduces irritation and, conversely, that sleep interruption will increase irritation.”

Researchers additionally discovered disturbing proof within the mice mannequin examine that these results could also be long-lasting. 

“That is necessary as a result of it’s yet one more key remark that sleep reduces irritation and, conversely, that sleep interruption will increase irritation,” Swirski mentioned in a information launch. 

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McAlpine advised Fox Information Digital that the aim of the examine was to higher perceive how continual sleep disruption could have an effect on cardiovascular circumstances that develop over time because of irritation. 

A new study looked at the long-term effects of chronic sleep deprivation — compared to the short-term interruption of sleep across a few days.

A brand new examine appeared on the long-term results of continual sleep deprivation — in comparison with the short-term interruption of sleep throughout just a few days.
(iStock)

These findings, he mentioned, could assist with analysis involving different inflammatory ailments and circumstances within the physique, similar to arthritis.

The examine checked out long-term results of continual sleep deprivation, mentioned McAlpine, in comparison with a short-term interruption in sleep over just a few days. 

He mentioned the examine helped establish organic mechanisms and pathways that hyperlink sleep and immune system well being over an extended interval. 

The group of members then decreased their sleep time by 90 minutes every evening for six weeks — and had their blood drawn and analyzed once more. 

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The investigators checked out 14 wholesome adults who frequently sleep eight hours an evening. 

Members have been monitored at first as they slept a minimum of eight hours an evening for six weeks. The crew of researchers took blood samples and analyzed the members’ immune cells. 

SLEEP DEPRIVATION MAY MAKE YOU MORE SELFISH, NEW STUDY SUGGESTS 

The group of members then decreased their sleep time by 90 minutes every evening for six weeks — and had their blood drawn and analyzed once more. 

All 14 participants in a new study had "significant changes" in their immune cells which were attributed to the lack of sleep, according to the findings.

All 14 members in a brand new examine had “important adjustments” of their immune cells which have been attributed to the dearth of sleep, in line with the findings.
(iStock)

The investigators in contrast the blood samples and located that every one 14 members had important adjustments of their immune cells that they attributed to the dearth of sleep.

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The decreased sleep blood samples confirmed an altered DNA construction and an elevated variety of immune cells. 

Sometimes, in a heightened state of irritation, well being specialists defined to Fox Information Digital that there are elevated numbers of immune cells. 

The heightened state of irritation within the mice that had fragmented sleep didn’t reverse even after sleep restoration, McAlpine additionally advised Fox Information Digital.

The researchers additionally appeared on the impact of sleep disruption in mice. 

Within the mice mannequin, teams of mice have been allowed to sleep undisturbed, whereas one other group was woke up all through the evening for 16 weeks. 

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The mice within the disrupted sleep group then went by uninterrupted sleep restoration for 10 weeks, in line with the report.

"Our findings suggest that sleep recovery is not able to fully reverse the effects of poor-quality sleep. We can detect a molecular imprint of insufficient sleep in immune stem cells, even after weeks of recovery sleep."

“Our findings counsel that sleep restoration is just not in a position to totally reverse the consequences of poor-quality sleep. We are able to detect a molecular imprint of inadequate sleep in immune stem cells, even after weeks of restoration sleep.”
(iStock)

The analysis crew analyzed the immune stem cells and the cells from the teams of mice — and the findings have been in line with the human examine, McAlpine mentioned.

“We present in [both] the human and mice fashions [that] should you disturb sleep, you get heightened irritation within the blood.” 

The heightened state of irritation within the mice that had fragmented sleep didn’t reverse even after sleep restoration, McAlpine additionally advised Fox Information Digital.

Not all stem cells responded to inadequate sleep in the identical method, he mentioned. 

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“Sadly, within the human examine, we didn’t assess restoration — however [we] did take a look at restoration in mice. And in mice, we discovered some parameters of irritation did return to common ranges with sleep restoration — nevertheless, not all.”  

McAlpine mentioned that some cells did stay (after the sleep restoration) that predisposed mice to irritation. 

In a information launch, the co-investigator mentioned, “Our findings counsel that sleep restoration is just not in a position to totally reverse the consequences of poor-quality sleep. We are able to detect a molecular imprint of inadequate sleep in immune stem cells, even after weeks of restoration sleep. This … may cause the cells to reply in inappropriate methods, resulting in irritation and illness.”

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McAlpine advised Fox Information Digital that the analysis crew plans extra examine to grasp what genes are being influenced by sleep — or pathways of genes which will reply to sleep. That may allow researchers to grasp the impacts of sleep in additional element.

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To keep your teeth white, bright and healthy, follow these 7 tips from dental experts

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To keep your teeth white, bright and healthy, follow these 7 tips from dental experts

Dental hygiene is important — as is taking pride in your “pearly whites.”

But keeping your teeth bright and white can be a challenge, with various factors causing discoloration.

Dr. Ronald Santana, head of science and development at Oral Biolife in Pennsylvania, noted that tooth discoloration refers to the “staining or darkening of teeth” from internal or external factors.

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“Extrinsic discoloration is caused by color changes of the tooth enamel by external factors such as smoking, foods or beverages, including coffee, tea and red wine,” he said in a statement to Fox News Digital.

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“Intrinsic discoloration affects the tooth dentin and is caused by some medications taken during childhood (tetracyclines), dental trauma and certain diseases (liver disease).”

One dentist’s rule is, “If it can stain a white T-shirt, it can stain your teeth.” (iStock)

Dr. Erin Fraundorf, owner of BOCA Orthodontic and Whitening Studio in Ladue, Missouri, agreed that numerous factors can cause the discoloring of teeth.

While there is “no way to know the cause without being evaluated and diagnosed by a professional,” the expert said that diet, smoking, medications, trauma, genetics, thin enamel and the wearing down of teeth via grinding and chewing can all lead to discoloration.

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“A good general rule of thumb is that if it can stain a white T-shirt, it can stain your teeth,” she told Fox News Digital.

Santana and Fraundorf offered seven tips on how to get your teeth whiter and brighter.

1. Develop an oral care routine

Fraundorf recommended brushing at least twice a day with an electric toothbrush and using toothpaste with fluoride or nano-hydroxyapatite (nHA).

“Avoid using charcoal or other abrasive toothpastes, as they damage enamel over time, making teeth darker,” she said.

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“Transform mundane oral care into a self-care ritual to make it an experience,” she added.

While some people might feel inclined to try at-home teeth-whitening remedies, Santana stressed that “care should be exercised in selecting a safe and effective at-home approach for tooth whitening.”

woman brushes teeth

Experts say it’s best to avoid using charcoal or other “abrasive” toothpastes. (iStock)

“Avoid trying at-home approaches before seeing a dentist, because some substances may damage the tooth enamel,” he warned.

“Adequate” toothbrushing is an “effective” way to reduce the discoloration of your teeth, according to Santana.

PRACTICE GOOD ORAL HYGIENE TO PROTECT YOURSELF AGAINST PERIODONTITIS

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“Tooth brushing with a correct brushing technique, employing a whitening dentifrice and using an electric toothbrush are effective resources to reduce tooth discoloration.”

Fraundorf added that flossing with toothpaste, using a water flosser to remove plaque and using a tongue scraper daily to decrease bacteria can also promote whiter teeth.

2. Drink more water

Water is “the best thing you can drink to keep your teeth healthy and white,” according to Fraundorf.

“Next time you have that cup of coffee or glass of red wine, take a swig of water in between sips and briefly swish around,” she advised. 

Woman reaches for water glass near bed

Water is “the best thing you can drink to keep your teeth healthy and white,” a dentist suggested. (iStock)

“Water will not only prevent the staining particles from clinging onto your teeth, it will also help neutralize the acidity of the beverage.”

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Fraundorf also recommended choosing flat water rather than sparkling.

“Drink and swish with it frequently to neutralize your oral environment and fight stains,” she suggested.

3. Chew sugar-free gum

Studies suggest that cavities are “significantly lower” in patients who chew sugar-free gum for 20 minutes after a meal, Fraundorf noted.

DENTISTS REVEAL WHY YOU SHOULDN’T BRUSH YOUR TEETH IN THE SHOWER

“Chewing sugar-free gum increases salivary flow by stimulating mechanical and taste receptors in the mouth,” she told Fox News Digital. 

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“Saliva helps wash away food particles as well as dilute and neutralize acids produced by plaque bacteria on teeth, leading to a reduction in cavities and stains.”

4. Drink through a straw

Using a straw, especially when drinking dark, acidic or sugary beverages, can help decrease the contact these substances make with your teeth.

woman drinking green juice health and fitness

Drinking through a straw decreases the liquid’s contact with your teeth, experts advised. (iStock)

“For extra credit, try drinking beverages more quickly to reduce the amount of time your oral environment is exposed to a lower pH, therefore decreasing the amount of enamel damage,” Fraundorf said.

5. Fight stains with fruits and veggies

Certain foods and drinks — such as red wine, soda, soy sauce, curry, balsamic vinegar and coffee — may stain your teeth and should be avoided, Santana said.

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“Moreover, although the scientific evidence is limited, consumption of a balanced, healthy diet — containing strawberries, grapes, apples, watermelon, papaya, pineapple, cheese, celery, carrots, broccoli and almonds — may limit tooth staining,” he noted.

Fraundorf agreed that “superfoods may be one of the best (and tastiest) ways to whiten your teeth naturally.”

woman bites into a strawberry

Superfoods like strawberries can help whiten teeth, according to experts. (iStock)

“Strawberries, apples and watermelon all contain a lot of malic acid, which helps whiten your smile by removing surface stains and increasing saliva,” she said.

Other superfoods that can help whiten teeth include celery and leafy greens, since their “fibrous textures act like a natural toothbrush, exfoliating plaque off your teeth,” Fraundorf added.

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“Dark, leafy greens also contain calcium, counteracting the effects of acids, and an abundance of folic acid, which is essential to gum tissue cell growth.”

6. Visit the dentist

“Maintaining excellent oral health is the most important thing you can do to achieve a bright smile,” Fraundorf told Fox News Digital.

“Set a calendar reminder to get regular check-ups and cleanings with your general dentist.”

Santana added, “Your dentist can prescribe safe and customized resources for tooth whitening tailored to your specific needs.”

woman checks out her teeth at the dentist

Patients should visit the dentist for a general check-up every six months, experts recommended. (iStock)

7. Consider professional teeth whitening

Although being diligent about oral care can help keep teeth bright, Fraundorf suggested that professional teeth whitening could be necessary to “take your smile to the next level.” 

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“Maintaining excellent oral health is the most important thing you can do to achieve a bright smile.”

“Whitening treatments are not one-size-fits-all, so it is important to seek customized care,” she said. 

“The most ideal whitening treatment is one specific to you, crafted based on your unique smile goals, teeth composition, diet, sensitivity level and lifestyle.”

She added, “A multitude of factors go into a proper diagnosis and customized treatment plan for teeth whitening to ensure the best, most comfortable, beautiful results.”

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Artificial tooth structures, like crowns, veneers and composites, won’t whiten, according to the expert — which means whitening these teeth will require extra restorative work.

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CrossFit for beginners: How to make the most of the fitness program

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CrossFit for beginners: How to make the most of the fitness program

CrossFit offers a unique fitness experience, blending a combination of high-intensity workouts with a supportive community.

It’s important for beginners to equip themselves with the knowledge necessary to ensure a safe and successful start before diving into the program.

Read on to learn more about the program and how newcomers can make the most of their CrossFit journey.

What is CrossFit?

CrossFit is a results-oriented fitness program with a focus on lifestyle changes through training.

The program’s workouts feature constantly varied, high-intensity and functional movements.

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Founded more than 20 years ago in a garage gym in Santa Cruz, California, CrossFit has since become one of the world’s most popular training programs for improving health and fitness performance.

CrossFit aims to help its members excel in various physical activities and challenges both inside and outside the gym.

CrossFit is known for its high-intensity workouts that blend elements from weightlifting, gymnastics and cardio. (CrossFit, LLC)

How is CrossFit different from other fitness programs?

CrossFit is known for its workouts that blend elements from weightlifting, gymnastics and cardio.

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The fitness company has more than 12,000 CrossFit affiliates spanning 146 countries, Austin Malleolo, senior director of strategy and operations of affiliates at CrossFit, told Fox News Digital.

“Our affiliates are staffed with trainers who are equipped to teach you how to move safely, effectively and efficiently,” Malleolo said. 

The CrossFit program is based on three pillars: variance, functionality and intensity.

CROSSFIT HIRES FORMER US MARINE AND TECH EXECUTIVE AS ITS NEW CEO

Variance is the practice of regularly changing workout routines and exercises. 

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By incorporating a wide variety of movements, variance provides CrossFit members with a broader range of physical challenges. This approach exposes the body to different stimuli, which promotes continual growth and adaptation.

A CrossFit class is a one-hour group session led by a coach.

Functionality is doing exercises that mimic real-life activities. By building strength, flexibility, endurance and coordination through functional movements, members can better navigate daily activities outside the gym.

Intensity is the level of effort exerted during workouts. While the word may seem intimidating, it’s simply a guiding principle that symbolizes the importance of working hard to achieve tangible results.

What does a CrossFit class look like?

A CrossFit class is a one-hour group session led by a coach.

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Typically, sessions begin with a whiteboard brief, where a coach outlines the workout flow, provides timing examples and demonstrates movements.

WE TRIED IT: CROSSFIT

Next, the coach discusses the goals of the workout, explaining the intended stimulus for members to understand the purpose behind the session. Scaling options are then provided for movements in the workout, allowing members to adjust based on their skill level.

Woman doing CrossFit exercise

CrossFit classes are designed to meet members at their current fitness levels and abilities. (CrossFit, LLC)

Physical activities begin with a general warm-up to get members moving and introduce movement patterns, followed by a specific warm-up tailored to the workout. The session’s main focus is devoted to the workout itself, where participants engage in the exercises outlined.

The session concludes with a cool-down, which incorporates stretching and mobility exercises to reduce muscle soreness. This approach allows members to receive a well-rounded workout experience.

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How does CrossFit accommodate those with different fitness levels?

CrossFit classes are designed to meet members at their current fitness levels and abilities, Malleolo told Fox News Digital.

“Coaches start by tailoring the workout of the day to allow for all members in the class to achieve the intended goals of the workout that day by having a robust warm-up that allows the members to properly warm up and practice the movements that they will be doing in the workout,” Malleolo said. “The coach will adjust the loading, reps, and time of the workout based on the member’s needs to align with that day’s workout.”

DOES CROSSFIT REALLY WORK?

Throughout the class, coaches teach and refine movements, offering guidance to improve performance.

CrossFit promotes inclusivity and accessibility by accommodating those with a range of fitness levels, allowing participants to progress safely at their own pace.

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Man doing CrossFit exercise

Starting your fitness journey can feel overwhelming, but with the right support, it becomes a powerful step toward a healthier lifestyle. (CrossFit, LLC)

How do I start CrossFit?

Starting your fitness journey can feel overwhelming, but with the right support, it becomes a powerful step toward a healthier lifestyle.

“Trust that the hardest part is to walk through the front door of the gym,” Malleolo said. “Once you are there, you will be taken care of! No matter where you are in your fitness journey, a CrossFit Affiliate is designed to be a part of that journey, no matter where you are today.”

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

You can begin the process by researching CrossFit locations near you and setting up an introductory session.

Many CrossFit facilities offer programs designed to teach newcomers the fundamental movements in a supportive environment, Malleolo told Fox News Digital.

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The program can be challenging, but it should also be enjoyable as well. 

Participants are encouraged to embrace the process, celebrate their achievements and cherish the friendships made within the CrossFit community.

For more Health articles, visit www.foxnews.com/health.

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5 women’s health tips to prevent and detect strokes, according to cardiologists

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5 women’s health tips to prevent and detect strokes, according to cardiologists

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One in five women between ages 55 and 75 will experience a stroke in their lifetime, according to the American Heart Association.

There are two main types of strokes.

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With an ischemic stroke, a blockage prevents blood from flowing properly to the brain. With a hemorrhagic stroke, a blood vessel bursts in the brain and causes bleeding, which damages brain cells.

While some risk factors such as age, race and family history can’t be changed, others can be mitigated through healthy lifestyle choices.

DOG ALERTS FAMILY, SAVES TEXAS TEENAGER FROM LIFE-THREATENING STROKE: ‘KEEPING GUARD’

Parag Shah, M.D., a cardiologist who practices at Brooks Rehabilitation in Jacksonville, Florida, shared some specific tips about how women can reduce their risk.

Here are five tips.

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Parag Shah, M.D., a cardiologist who practices at Brooks Rehabilitation in Jacksonville, Florida, shared specific tips about how women can reduce their risk of stroke. (Dr. Parag Shah)

1. Avoid air pollution 

Research has shown that air pollution tends to impact women more than men in terms of inflammation, infection and heart disease.

CDC WARNS OF EXTREME HEAT DANGERS AMID ‘RECORD-BREAKING HIGH TEMPERATURES’

“According to a recent review, elevated levels of ambient air pollution — even just short-term exposure — can increase the likelihood of strokes,” said Shah, who specializes in stroke rehabilitation.

“Health experts recommend checking the air quality in your area and, on high-pollution days, limiting time outside, turning on exhaust fans in kitchens and bathrooms, and using an air purifier in the home,” he also said.

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2. Embrace the Mediterranean diet 

The Mediterranean diet — a plant-based nutrition plan that mimics the regional cuisines of the countries along the Mediterranean Sea, such as Italy and Greece — can reduce the health risks associated with strokes, according to Shah.

“Current research on preventing strokes is exploring an array of lifestyle factors,” he told Fox News Digital. 

Stroke prevention split

While some risk factors — such as age, race and family history — can’t be changed, others can be mitigated through healthy lifestyle choices. (iStock)

“This includes the Mediterranean diet, which highlights the consumption of fruits, vegetables, whole grains, nuts, olive oil and foods rich in omega-3 fatty acids like fatty fish, walnuts and flaxseed.” 

MEDITERRANEAN, MIND DIETS SHOWN TO REDUCE SIGNS OF ALZHEIMER’S IN THE BRAIN, STUDY FINDS

3. Practice tai chi and yoga 

Practicing exercises that promote heart health and lessen stress can help reduce the possibility of stroke, Shah suggested. 

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People doing yoga

Practicing exercises that promote heart health and reduce stress can help reduce the possibility of stroke, a doctor said. (iStock)

“Participating in physical activities like yoga, tai chi and strength training, while also giving importance to mindfulness techniques such as meditation and deep breathing exercises, could provide additional advantages in lowering the risk of strokes,” he told Fox News Digital.

4. Know the less common signs of stroke

Sudden confusion, difficulty understanding, slurred speech, double vision, and numbness or weakness, especially on one side of the body, are often overlooked signs of strokes, Shah warned.

TIAS AND MINI-STROKE RISKS: CARDIOLOGIST SHARES WARNING SIGNS AND PREVENTION TIPS

“Recognizing these signs is crucial, because quick identification and immediate medical attention greatly enhance the chances of recovery for stroke patients,” he said.

5. Understand the hidden causes 

Beyond the more obvious “textbook” stroke symptoms, there are some warning signs that tend to be overlooked until it’s too late.

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“Factors like pregnancy, giving birth and hormonal changes such as menopause can heighten the likelihood of having a stroke,” Shah told Fox News Digital. 

Woman holding pills

The use of oral contraceptives and hormone therapy can also raise the risk of stroke, doctors advised. (iStock)

The use of oral contraceptives and hormone therapy can also raise this risk, the doctor added, as can hidden biological factors that make women more susceptible. 

“Scheduling regular health check-ups and staying knowledgeable about stroke symptoms and prevention methods are essential for maintaining good health,” Shah said.

In addition, know ‘Life’s Essential 8’

“Preventing most strokes is similar to the prevention of heart attacks,” Dr. Laxmi Mehta, a cardiologist and director of preventative cardiology and women’s cardiovascular health at The Ohio State University Wexner Medical Center, told Fox News Digital.

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In her practice, Mehta typically recommends following the American Heart Association’s Life’s Essential 8, which provides steps to improve or maintain cardiovascular health.  

These include four healthy behaviors and four health factors, as listed below.

Life's essential 8

“Life’s Essential 8” consists of four healthy behaviors and four health factors. (iStock/American Heart Association)

1. Quit tobacco. Avoid cigarettes, vaping and other nicotine products, which have been proven to increase the risk of strokes and heart attacks.

2. Eat better. Following a healthy eating pattern that includes plenty of fresh fruits and veggies, whole grains, lean protein, nuts and seeds can reduce stroke risk.

3. Be more active. Experts recommend participating in 150 minutes of moderate intensity or 75 minutes of vigorous physical activity weekly.

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4. Get healthy sleep. Adults should aim for seven to nine hours of sleep per night to reduce stroke risk, according to experts.

5. Manage blood pressure. A “normal” blood pressure is defined as a systolic pressure of less than 120 and a diastolic pressure of less than 80, according to the National Institutes of Health.

Healthy eating

Following a healthy eating pattern that includes plenty of fresh fruits and veggies, whole grains, lean protein, nuts and seeds can reduce stroke risk. (iStock)

6. Manage cholesterol. High cholesterol levels have a proven link to stroke risk. A healthy range for LDL (“bad”) cholesterol is 100 mg/dL or lower, as published in the Journal of the American College of Cardiology.

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7. Manage blood sugar. Excessive levels of glucose in the blood can increase the risk of fatty deposits or clots, which are a factor in strokes.

8. Achieve and maintain a healthy weight. Being overweight or obese is one of the biggest risk factors and is linked to nearly one in five strokes, according to the World Stroke Organization.

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