Science
Opinion: America's 'big glass' dominance hangs on the fate of two powerful new telescopes
More than 100 years ago, astronomer George Ellery Hale brought our two Pasadena institutions together to build what was then the largest optical telescope in the world. The Mt. Wilson Observatory changed the conception of humankind’s place in the universe and revealed the mysteries of the heavens to generations of citizens and scientists alike. Ever since then, the United States has been at the forefront of “big glass.”
In fact, our institutions, Carnegie Science and Caltech, still help run some of the largest telescopes for visible-light astronomy ever built.
But that legacy is being threatened as the National Science Foundation, the federal agency that supports basic research in the U.S., considers whether to fund two giant telescope projects. What’s at stake is falling behind in astronomy and cosmology, potentially for half a century, and surrendering the scientific and technological agenda to Europe and China.
In 2021, the National Academy of Sciences released Astro2020. This report, a road map of national priorities, recommended funding the $2.5-billion Giant Magellan Telescope at the peak of Cerro Las Campanas in Chile and the $3.9-billion Thirty Meter Telescope at Mauna Kea in Hawaii. According to those plans, the telescopes would be up and running sometime in the 2030s.
NASA and the Department of Energy backed the plan. Still, the National Science Foundation’s governing board on Feb. 27 said it should limit its contribution to $1.6 billion, enough to move ahead with just one telescope. The NSF intends to present their process for making a final decision in early May, when it will also ask for an update on nongovernmental funding for the two telescopes. The ultimate arbiter is Congress, which sets the agency’s budget.
America has learned the hard way that falling behind in science and technology can be costly. Beginning in the 1970s, the U.S. ceded its powerful manufacturing base, once the nation’s pride, to Asia. Fast forward to 2022, the U.S. government marshaled a genuine effort toward rebuilding and restarting its factories — for advanced manufacturing, clean energy and more — with the Inflation Reduction Act, which is expected to cost more than $1 trillion.
President Biden also signed into law the $280-billion CHIPS and Science Act two years ago to revive domestic research and manufacturing of semiconductors — which the U.S. used to dominate — and narrow the gap with China.
As of 2024, America is the unquestioned leader in astronomy, building powerful telescopes and making significant discoveries. A failure to step up now would cede our dominance in ways that would be difficult to remedy.
The National Science Foundation’s decision will be highly consequential. Europe, which is on the cusp of overtaking the U.S. in astronomy, is building the aptly named Extremely Large Telescope, and the United States hasn’t been invited to partner in the project. Russia aims to create a new space station and link up with China to build an automated nuclear reactor on the moon.
Although we welcome any sizable grant for new telescope projects, it’s crucial to understand that allocating funds sufficient for just one of the two planned telescopes won’t suffice. The Giant Magellan and the Thirty Meter telescopes are designed to work together to create capabilities far greater than the sum of their parts. They are complementary ground stations. The GMT would have an expansive view of the southern hemisphere heavens, and the TMT would do the same for the northern hemisphere.
The goal is “all-sky” observation, a wide-angle view into deep space. Europe’s Extremely Large Telescope won’t have that capability. Besides boosting America’s competitive edge in astronomy, the powerful dual telescopes, with full coverage of both hemispheres, would allow researchers to gain a better understanding of phenomena that come and go quickly, such as colliding black holes and the massive stellar explosions known as supernovas. They would put us on a path to explore Earth-like planets orbiting other suns and address the question: “Are we alone?”
Funding both the GMT and TMT is an investment in basic science research, the kind of fundamental work that typically has led to economic growth and innovation in our uniquely American ecosystem of scientists, investors and entrepreneurs.
Elon Musk’s SpaceX is the most recent example, but the synergy goes back decades. Basic science at the vaunted Bell Labs, in part supported by taxpayer contributions, was responsible for the transistor, the discovery of cosmic microwave background and establishing the basis of modern quantum computing. The internet, in large part, started as a military communications project during the Cold War.
Beyond its economic ripple effect, basic research in space and about the cosmos has played an outsized role in the imagination of Americans. In the 1960s, Dutch-born American astronomer Maarten Schmidt was the first scientist to identify a quasar, a star-like object that emits radio waves, a discovery that supported a new understanding of the creation of the universe: the Big Bang. The first picture of a black hole, seen with the Event Horizon Telescope, was front-page news in 2019.
We understand that competing in astronomy has only gotten more expensive, and there’s a need to concentrate on a limited number of critical projects. But what could get lost in the shuffle are the kind of ambitious projects that have made America the scientific envy of the world, inspiring new generations of researchers and attracting the best minds in math and science to our colleges and universities.
Do we really want to pay that price?
Eric D. Isaacs is the president of Carnegie Science, prime backer of the Giant Magellan Telescope. Thomas F. Rosenbaum is president of Caltech, key developer of the Thirty Meter Telescope.
Science
What’s in a Name? For These Snails, Legal Protection
The sun had barely risen over the Pacific Ocean when a small motorboat carrying a team of Indigenous artisans and Mexican biologists dropped anchor in a rocky cove near Bahías de Huatulco.
Mauro Habacuc Avendaño Luis, one of the craftsmen, was the first to wade to shore. With an agility belying his age, he struck out over the boulders exposed by low tide. Crouching on a slippery ledge pounded by surf, he reached inside a crevice between two rocks. There, lodged among the urchins, was a snail with a knobby gray shell the size of a walnut. The sight might not dazzle tourists who travel here to see humpback whales, but for Mr. Avendaño, 85, these drab little mollusks represent a way of life.
Marine snails in the genus Plicopurpura are sacred to the Mixtec people of Pinotepa de Don Luis, a small town in southwestern Oaxaca. Men like Mr. Avendaño have been sustainably “milking” them for radiant purple dye for at least 1,500 years. The color suffuses Mixtec textiles and spiritual beliefs. Called tixinda, it symbolizes fertility and death, as well as mythic ties between lunar cycles, women and the sea.
The future of these traditions — and the fate of the snails — are uncertain. The mollusks are subject to intense poaching pressure despite federal protections intended to protect them. Fishermen break them (and the other mollusks they eat) open and sell the meat to local restaurants. Tourists who comb the beaches pluck snails off the rocks and toss them aside.
A severe earthquake in 2020 thrust formerly submerged parts of their habitat above sea level, fatally tossing other mollusks in the snail’s food web to the air, and making once inaccessible places more available to poachers.
Decades ago, dense clusters of snails the size of doorknobs were easy to find, according to Mr. Avendaño. “Full of snails,” he said, sweeping a calloused, violet-stained hand across the coves. Now, most of the snails he finds are small, just over an inch, and yield only a few milliliters of dye.
Science
Video: This Parrot Has No Beak, But Is at the Top of the Pecking Order
new video loaded: This Parrot Has No Beak, But Is at the Top of the Pecking Order
By Meg Felling and Carl Zimmer
April 20, 2026
Science
Contributor: Focus on the real causes of the shortage in hormone treatments
For months now, menopausal women across the U.S. have been unable to fill prescriptions for the estradiol patch, a long-established and safe hormone treatment. The news media has whipped up a frenzy over this scarcity, warning of a long-lasting nationwide shortage. The problem is real — but the explanations in the media coverage miss the mark. Real solutions depend on an accurate understanding of the causes.
Reporters, pharmaceutical companies and even some doctors have blamed women for causing the shortage, saying they were inspired by a “menopause moment” that has driven unprecedented demand. Such framing does a dangerous disservice to essential health advocacy.
In this narrative, there has been unprecedented demand, and it is explained in part by the Food and Drug Administration’s recent removal of the “black-box warning” from estradiol patches’ packaging. That inaccurate (and, quite frankly, terrifying) label had been required since a 2002 announcement overstated the link between certain menopause hormone treatments and breast cancer. Right-sizing and rewording the warning was long overdue. But the trouble with this narrative is that even after the black-box warning was removed, there has not been unprecedented demand.
Around 40% of menopausal women were prescribed hormone treatments in some form before the 2002 announcement. Use plummeted in its aftermath, dipping to less than 5% in 2020 and just 1.8% in 2024. According to the most recent data, the number has now settled back at the 5% mark. Unprecedented? Hardly. Modest at best.
Nor is estradiol a new or complex drug; the patch formulation has existed for decades, and generic versions are widely manufactured. There is no exotic ingredient, no rare supply chain dependency, no fluke that explains why women are suddenly being told their pharmacy is out of stock month after month.
The story is far more an indictment of the broken insurance industry: market concentration, perverse incentives and the consequences of allowing insurance companies to own the pharmacy benefit managers that effectively control drug access for the majority of users. Three companies — CVS Caremark, Express Scripts and OptumRx — manage 79% of all prescription drug claims in the United States. Those companies are wholly owned subsidiaries of three insurance behemoths: CVS Health, Cigna and UnitedHealth Group, respectively. This means that the same corporation that sells you your insurance plan also decides which drugs get covered, at what price, and whether your pharmacy can stock them. This is called vertical integration. In another era, we might have called it a cartel. The resulting problems are not unique to hormone treatments; they have affected widely used medications including blood thinners, inhalers and antibiotics. When a low-cost generic such as estradiol — a medication with no blockbuster profit margins and no patent protection — runs into friction in this system, the friction is not random. It is structural. Every decision in that chain is filtered through the same corporate profit motive. And when the drug in question is an off-patent estradiol patch that has negligible profit margins because of generic competition but requires logistical investment to keep consistently in stock? The math on “how much does this company care about ensuring access” is not complicated.
Unfortunately, there is little financial incentive to ensure smooth, consistent access. There is, however, significant financial incentive to steer patients toward branded alternatives, or simply to let supply tighten — because the companies aren’t losing much profit if sales of that product dwindle. This is not a conspiracy theory: The Federal Trade Commission noted this dynamic in a report that documented how pharmacy benefit managers’ practices inflate costs, reduce competition and harm patient access, particularly for independent pharmacies and for generic drugs.
Any claim that the estradiol patch shortage is meaningfully caused by more women now demanding hormone treatments is a distraction. It is also misogyny, pure and simple, to imply that the solution to the shortage is for women’s health advocates to dial it down and for women to temper their expectations. The scarcity of estradiol patches is the outcome of a broken system refusing to provide adequate supply.
Meanwhile, there are a few strategies to cope.
- Ask your prescriber about alternatives. Estradiol is available in multiple formulations, including gel, spray, cream, oral tablet, vaginal ring and weekly transdermal patch, which is a different product from the twice-weekly patch and may be more consistently available depending on manufacturer and region.
- Consider an online pharmacy. Many are doing a good job locating and filling these prescriptions from outside the pharmacy benefit manager system.
- Call ahead. Patch shortages are inconsistent across regions and distributors. A call to pharmacies in your area, or a broader geographic radius if you’re able, can locate stock that your regular pharmacy doesn’t have.
- Consider a compounding pharmacy. These sources can sometimes meet needs when commercially manufactured products are inaccessible. The hormones used are the same FDA-regulated bulk ingredients.
Beyond those Band-Aid solutions, more Americans need to fight for systemic change. The FTC report exists because Congress asked for it and committed to legislation that will address at least some of the problems. The FDA took action to change the labeling on estrogen in the face of citizen and medical experts’ pressure; it should do more now to demand transparency from patch manufacturers.
Most importantly, it is on all of us to call out the cracks in the current system. Instead of repeating “there’s a patch shortage” or a “surge in demand,” say that a shockingly small minority of menopausal women still even get hormonal treatments prescribed at all, and three drug companies control the vast majority of claims in this country. Those are the real problems that need real solutions.
Jennifer Weiss-Wolf, the executive director of the Birnbaum Women’s Leadership Center at New York University School of Law, is the author of the forthcoming book “When in Menopause: A User’s Manual & Citizen’s Guide.” Suzanne Gilberg, an obstetrician and gynecologist in Los Angeles, is the author of “Menopause Bootcamp.”
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