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NASA's attempt to bring home part of Mars is unprecedented. The mission's problems are not

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NASA's attempt to bring home part of Mars is unprecedented. The mission's problems are not

Massive cost overruns. Key deadlines slipping out of reach. Problems of unprecedented complexity, and a generation’s worth of scientific progress contingent upon solving them.

That’s the current state of Mars Sample Return, the ambitious yet imperiled NASA mission whose rapidly ballooning budget has cost jobs at NASA’s Jet Propulsion Laboratory in La Cañada Flintridge and drawn threats of cancellation from lawmakers.

But not all that long ago, those same dire circumstances described the James Webb Space Telescope, the pioneering infrared scope that launched on Christmas Day 2021.

The biggest space telescope ever has so far proved to be a scientific and public relations victory for NASA. The telescope’s performance has surpassed all expectations, senior project scientist Jane Rigby said at a meeting recently.

Its first images were so hotly anticipated that the White House scooped NASA’s announcement, releasing a dazzling view of thousands of galaxies the day before the space agency shared the first batch of pictures. Thousands of researchers have since applied for observation time.

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“The world has been rooting for this telescope to succeed,” Rigby told the National Academies’ committee on astronomy and astrophysics.

Yet in the years before launch, the success and acclaim Webb now enjoys were far from guaranteed.

The telescope cost twice as much as initially anticipated and launched seven years behind its original schedule. Some members of Congress at one point tried to pull funding from the project. Even the journal Nature referred to it at the time as the “telescope that ate astronomy.”

After a thorough assessment of the project’s needs and flaws, NASA was able to turn the troubled venture around. Supporters of Mars Sample Return are hopeful that mission will follow a similar trajectory.

“A lot of great science will come out of” Mars Sample Return, said Garth Illingworth, an astronomer emeritus at UC Santa Cruz and former deputy director of the project that is now the James Webb Space Telescope. “But they’ve got to get real as to how to manage this.”

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Last year was a crisis point for Mars Sample Return, whose goal is to fetch rocks from the Red Planet’s Jezero crater and bring them back to Earth for study.

In July, the U.S. Senate presented NASA with an ultimatum in its proposed budget: Either present a plan for completing the mission within the $5.3 billion budgeted, or risk cancellation. A sobering independent review found in September that there was “near zero probability” of Mars Sample Return making its proposed 2028 launch date, and “no credible” way to fulfill the mission within its current budget. NASA is due to respond to that report this month.

These tubes hold samples of rock cores and regolith (broken rock and dust) collected by NASA’s Perseverance rover for the Mars Sample Return campaign, which aims to bring bits of Mars back to Earth for closer study.

(NASA / JPL-Caltech / MSSS)

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The James Webb Space Telescope was further along in its development journey when it reached a similar crossroads in 2010, six years after construction began. Frustrated with the ballooning budget and constantly postponed launch date, the U.S. House of Representatives included no funding for the telescope in its proposed budget, which would have ended the project had the Senate agreed.

In a statement, lawmakers castigated the mission as “billions of dollars over budget and plagued by poor management,” foreshadowing the criticisms that would be leveled at Mars Sample Return more than a decade later.

To forestall cancellation, Sen. Barbara Mikulski (D-Md.) ordered an independent review of the project, which was under construction in her state.

The board determined that Webb’s problems stemmed from a “badly flawed” initial budget. All the technical expertise needed to complete this ambitious project was there, the evaluators concluded. But getting it done with the amount of money currently set aside would be virtually impossible.

Illingworth remembered that review when he read the Mars Sample Return assessment, which offered a similarly stark conclusion.

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“Some of the words are very familiar,” he said with a chuckle.

When the Mikulski review came out in 2010, Illingworth was deputy director of the Space Telescope Science Institute, which now leads science and operations for the James Webb Space Telescope.

With its powerful infrared vision and extremely high spatial resolution, the James Webb Space Telescope shows never-before-seen details in an image mosaic of the galaxy group known as Stephan’s Quintet.

(Space Telescope Science Institute / NASA, ESA, CSA, STScI, Webb ERO)

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He was sympathetic to the challenges facing Mars Sample Return managers, though chagrined that the James Webb Space Telescope’s hard-earned lessons have apparently faded so quickly — especially the importance of having a realistic budget from the beginning.

NASA missions are managed by very smart people with established histories of doing very hard things. How does something as terrestrially mundane as budgeting continually trip them up?

“The problem is that the models that you have as a cost estimator — and they have very complex proprietary software models that attempt to understand these types of things — are all built on things that have happened, in the past tense,” said Casey Dreier, chief of space policy for the Planetary Society.

“By definition, when you’re trying something completely new, it’s very hard to estimate in advance how much something unprecedented will cost,” Dreier said. “That happened for Apollo, that happened for the space shuttle, it happened for James Webb, and it’s happening now for Mars Sample Return.”

Mars Sample Return also has some mission-specific challenges that Webb didn’t have to contend with. For one, it’s happening at the same time as Artemis, NASA’s wildly expensive mission to return people to the moon.

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Expected to cost $93 billion through 2025, Artemis got a 27% increase in its budget over the previous year, while Mars Sample Return’s guaranteed funding is 63% less than last year’s spend.

And while NASA’s ambitions are growing, its funding from Congress, adjusted for inflation, has been essentially flat for decades. That leaves little room for unexpected extras.

“We are tasking the space agency with the most ambitious slate of programs in space since the Apollo era, but instead of Apollo-era budgets, it has one-third of 1% of U.S. spending to work with,” Dreier said. “If you stumble right now, the wolves will come for you. And that’s what is happening to Mars Sample Return.”

Not all ambitious scientific endeavors survive the kind of scrutiny the sample return is facing. In 1993 Congress canceled the U.S. Department of Energy’s Superconducting Super Collider, an underground particle accelerator, citing concerns about rising costs and fiscal mismanagement. The government had already spent $2 billion on the project and dug 14 miles of tunnel.

But in the same week that Congress ended the supercollider, it agreed — by a margin of a single vote — to continue funding the International Space Station, a similarly expensive project whose cost overruns had been widely criticized. ISS launched in November 1998 and is still going strong. (For now, anyway — NASA will intentionally crash it into the sea in 2030.)

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The space station’s future was never seriously threatened again after that painfully close vote, just as Webb’s future was never seriously questioned after the 2010 cancellation threat.

JPL, the institution managing Mars Sample Return, has already paid dearly for the mission’s initial stumbles, laying off more than 600 employees and 40 contractors after NASA ordered it to reduce its spending.

But projects that survive this kind of reckoning often emerge “stronger and more resilient,” Dreier said. “They know the eyes of the nation and NASA and Congress are on them, so you have to perform.”

NASA is set to reveal this month how it plans to move forward with Mars Sample Return. Those familiar with the mission say they believe it can still happen — and that it’s still worth doing.

“Do I have faith in NASA, JPL, all of those involved to be able to deliver on the Mars Sample Return mission with the attention and technical integrity that it requires? Absolutely,” said Orlando Figueroa, chair of the the mission’s independent review team and NASA’s former “Mars Czar.”

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“It will require very difficult decisions and levels of commitment, including from Congress, NASA and the administration, [and] a recognition of the importance, just like was the case with James Webb, for what this mission means for space science.”

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What’s in a Name? For These Snails, Legal Protection

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What’s in a Name? For These Snails, Legal Protection

The sun had barely risen over the Pacific Ocean when a small motorboat carrying a team of Indigenous artisans and Mexican biologists dropped anchor in a rocky cove near Bahías de Huatulco.

Mauro Habacuc Avendaño Luis, one of the craftsmen, was the first to wade to shore. With an agility belying his age, he struck out over the boulders exposed by low tide. Crouching on a slippery ledge pounded by surf, he reached inside a crevice between two rocks. There, lodged among the urchins, was a snail with a knobby gray shell the size of a walnut. The sight might not dazzle tourists who travel here to see humpback whales, but for Mr. Avendaño, 85, these drab little mollusks represent a way of life.

Marine snails in the genus Plicopurpura are sacred to the Mixtec people of Pinotepa de Don Luis, a small town in southwestern Oaxaca. Men like Mr. Avendaño have been sustainably “milking” them for radiant purple dye for at least 1,500 years. The color suffuses Mixtec textiles and spiritual beliefs. Called tixinda, it symbolizes fertility and death, as well as mythic ties between lunar cycles, women and the sea.

The future of these traditions — and the fate of the snails — are uncertain. The mollusks are subject to intense poaching pressure despite federal protections intended to protect them. Fishermen break them (and the other mollusks they eat) open and sell the meat to local restaurants. Tourists who comb the beaches pluck snails off the rocks and toss them aside.

A severe earthquake in 2020 thrust formerly submerged parts of their habitat above sea level, fatally tossing other mollusks in the snail’s food web to the air, and making once inaccessible places more available to poachers.

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Decades ago, dense clusters of snails the size of doorknobs were easy to find, according to Mr. Avendaño. “Full of snails,” he said, sweeping a calloused, violet-stained hand across the coves. Now, most of the snails he finds are small, just over an inch, and yield only a few milliliters of dye.

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Video: This Parrot Has No Beak, But Is at the Top of the Pecking Order

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Video: This Parrot Has No Beak, But Is at the Top of the Pecking Order

new video loaded: This Parrot Has No Beak, But Is at the Top of the Pecking Order

Bruce, a disabled kea parrot, is missing his top beak. The bird uses tools to keep himself healthy and developed a jousting technique that has made him the alpha male of his group.

By Meg Felling and Carl Zimmer

April 20, 2026

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Contributor: Focus on the real causes of the shortage in hormone treatments

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Contributor: Focus on the real causes of the shortage in hormone treatments

For months now, menopausal women across the U.S. have been unable to fill prescriptions for the estradiol patch, a long-established and safe hormone treatment. The news media has whipped up a frenzy over this scarcity, warning of a long-lasting nationwide shortage. The problem is real — but the explanations in the media coverage miss the mark. Real solutions depend on an accurate understanding of the causes.

Reporters, pharmaceutical companies and even some doctors have blamed women for causing the shortage, saying they were inspired by a “menopause moment” that has driven unprecedented demand. Such framing does a dangerous disservice to essential health advocacy.

In this narrative, there has been unprecedented demand, and it is explained in part by the Food and Drug Administration’s recent removal of the “black-box warning” from estradiol patches’ packaging. That inaccurate (and, quite frankly, terrifying) label had been required since a 2002 announcement overstated the link between certain menopause hormone treatments and breast cancer. Right-sizing and rewording the warning was long overdue. But the trouble with this narrative is that even after the black-box warning was removed, there has not been unprecedented demand.

Around 40% of menopausal women were prescribed hormone treatments in some form before the 2002 announcement. Use plummeted in its aftermath, dipping to less than 5% in 2020 and just 1.8% in 2024. According to the most recent data, the number has now settled back at the 5% mark. Unprecedented? Hardly. Modest at best.

Nor is estradiol a new or complex drug; the patch formulation has existed for decades, and generic versions are widely manufactured. There is no exotic ingredient, no rare supply chain dependency, no fluke that explains why women are suddenly being told their pharmacy is out of stock month after month.

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The story is far more an indictment of the broken insurance industry: market concentration, perverse incentives and the consequences of allowing insurance companies to own the pharmacy benefit managers that effectively control drug access for the majority of users. Three companies — CVS Caremark, Express Scripts and OptumRx — manage 79% of all prescription drug claims in the United States. Those companies are wholly owned subsidiaries of three insurance behemoths: CVS Health, Cigna and UnitedHealth Group, respectively. This means that the same corporation that sells you your insurance plan also decides which drugs get covered, at what price, and whether your pharmacy can stock them. This is called vertical integration. In another era, we might have called it a cartel. The resulting problems are not unique to hormone treatments; they have affected widely used medications including blood thinners, inhalers and antibiotics. When a low-cost generic such as estradiol — a medication with no blockbuster profit margins and no patent protection — runs into friction in this system, the friction is not random. It is structural. Every decision in that chain is filtered through the same corporate profit motive. And when the drug in question is an off-patent estradiol patch that has negligible profit margins because of generic competition but requires logistical investment to keep consistently in stock? The math on “how much does this company care about ensuring access” is not complicated.

Unfortunately, there is little financial incentive to ensure smooth, consistent access. There is, however, significant financial incentive to steer patients toward branded alternatives, or simply to let supply tighten — because the companies aren’t losing much profit if sales of that product dwindle. This is not a conspiracy theory: The Federal Trade Commission noted this dynamic in a report that documented how pharmacy benefit managers’ practices inflate costs, reduce competition and harm patient access, particularly for independent pharmacies and for generic drugs.

Any claim that the estradiol patch shortage is meaningfully caused by more women now demanding hormone treatments is a distraction. It is also misogyny, pure and simple, to imply that the solution to the shortage is for women’s health advocates to dial it down and for women to temper their expectations. The scarcity of estradiol patches is the outcome of a broken system refusing to provide adequate supply.

Meanwhile, there are a few strategies to cope.

  • Ask your prescriber about alternatives. Estradiol is available in multiple formulations, including gel, spray, cream, oral tablet, vaginal ring and weekly transdermal patch, which is a different product from the twice-weekly patch and may be more consistently available depending on manufacturer and region.
  • Consider an online pharmacy. Many are doing a good job locating and filling these prescriptions from outside the pharmacy benefit manager system.
  • Call ahead. Patch shortages are inconsistent across regions and distributors. A call to pharmacies in your area, or a broader geographic radius if you’re able, can locate stock that your regular pharmacy doesn’t have.
  • Consider a compounding pharmacy. These sources can sometimes meet needs when commercially manufactured products are inaccessible. The hormones used are the same FDA-regulated bulk ingredients.

Beyond those Band-Aid solutions, more Americans need to fight for systemic change. The FTC report exists because Congress asked for it and committed to legislation that will address at least some of the problems. The FDA took action to change the labeling on estrogen in the face of citizen and medical experts’ pressure; it should do more now to demand transparency from patch manufacturers.

Most importantly, it is on all of us to call out the cracks in the current system. Instead of repeating “there’s a patch shortage” or a “surge in demand,” say that a shockingly small minority of menopausal women still even get hormonal treatments prescribed at all, and three drug companies control the vast majority of claims in this country. Those are the real problems that need real solutions.

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Jennifer Weiss-Wolf, the executive director of the Birnbaum Women’s Leadership Center at New York University School of Law, is the author of the forthcoming book When in Menopause: A User’s Manual & Citizen’s Guide. Suzanne Gilberg, an obstetrician and gynecologist in Los Angeles, is the author of “Menopause Bootcamp.”

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