Health
Drinking 100% orange juice is linked to surprising health benefits, study finds
Pure orange juice might have some unexpected benefits.
Researchers from Toronto Metropolitan University researched the effects of drinking 100% orange juice compared to a sugar-sweetened beverage (SSB), or “orange drink,” on appetite, food intake and glycemic response in adults.
The study was funded by the Florida Department of Citrus. It was published in the journal Nutrients and also surveyed emotions and sensory characteristics associated with the beverage.
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Thirty-six “normal weight” adults were tasked with drinking either 100% orange juice, an orange drink or water before eating.
The researchers found that food and energy intake was lower in subjects who drank 100% orange juice compared to the orange drink.
“A little bit of orange seems to go a long way,” study co-author Nick Bellissimo told Fox News Digital. (iStock)
Caloric compensation from 100% orange juice was 84%, while the orange drink was −25%.
(Caloric compensation is the “regulation of energy intake by adjusting one’s intake based on previous consumption,” according to the National Institutes of Health.)
There was no significant difference in average appetite between the beverages, but blood glucose levels were lower after people drank the 100% orange juice.
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“Rest-of-day blood glucose concentrations were lower after 100% orange juice compared with the orange drink and water control,” the study stated.
“In conclusion, consumption of 100% orange juice as a preload resulted in higher caloric compensation, lower total daily EI [energy intake], and lower blood glucose concentrations compared to the orange drink.”
The researchers’ hypothesis was that the flavonoids in 100% orange juice slow down the digestion and absorption of sugar. (iStock)
Study co-author Nick Bellissimo, associate professor of nutritional physiology at Toronto Metropolitan University, reacted to the findings in a statement to Fox News Digital.
While a “number of dietary guidelines” recommend reducing sugar intake from “all sources,” Bellissimo said, the findings suggested that 100% orange juice can be beneficial.
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“Orange juice is similar to a sugar-sweetened beverage in that it contains free sugars, but it also contains sucrose (fructose and glucose bound together), while also containing vitamin C and flavonoids,” he noted.
The researchers’ hypothesis was that flavonoids in orange juice slow down the digestion and absorption of sugar.
“Thus, you are not seeing the same spike in blood glucose as you see with the SSB,” Bellissimo said.
Study participants who consumed orange drinks ate more calories at lunch than the 100% orange juice drinkers. (iStock)
“Interestingly, the energy in the orange juice was compensated for at the next meal – i.e., participants decreased their food intake at lunch by an amount similar to the energy in the orange juice – whereas participants ate more calories at lunch after consuming the SSB.”
Bellissimo confirmed that this effect on energy intake and glycemic response “persisted for the rest of the day.”
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“And participants consuming the orange juice actually consumed fewer calories, primarily by decreasing their carbohydrate intake,” he said.
“A little bit of orange seems to go a long way,” Bellissimo added.
People who drink 100% orange juice should mix it with some water for a more positive blood sugar result, a registered dietitian suggested. (iStock)
Ilana Muhlstein, a registered dietitian and nutritionist in Los Angeles, was not involved in the study but shared her thoughts on the study with Fox News Digital.
“The most important finding of the entire study is that the blood glucose concentrations were lower after 100% orange juice compared with an orange drink of the same calories, which shows that the body can recognize a difference between natural sugars and added sugars,” she said.
“The body can recognize a difference between natural sugars and added sugars.”
As a dietitian, Muhlstein said she is “constantly encouraging people to drink water,” especially prior to their meals, just as done in the study.
“It’s important to note that drinking water has a meaningful impact on lowering blood sugar levels,” she also pointed out.
“If someone wanted to drink orange juice, I would encourage them to stick with 100% orange juice, versus an ‘orange drink’ sweetened with sugar, and do their best to mix it with some water for a more positive blood sugar result.”
Fox News Digital reached out to the Florida Department of Citrus for comment.
For more Health articles, visit www.foxnews.com.com/health.
Medical expert analyzes trending IV therapy, concerns about peptides
Dr. Mike Varshavski joins ‘Fox & Friends’ for Wellness Week, examining trending self-care treatments. He evaluates IV vitamin therapy, highlighting its hospital-critical role versus unproven benefits for general wellness, citing potential risks like vitamin imbalance. Dr. Mike also differentiates creatine, a research-backed supplement, from unregulated peptides marketed with unverified anti-aging and muscle growth promises, urging caution for patients.
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We are officially living in the “maxxing” era.
From “looksmaxxing” to improve appearance to “sleepmaxxing” for better rest, these viral terms all point to the same goal: squeezing every ounce of potential out of a specific trait or habit.
With a growing focus on optimizing wellness and maximizing longevity, the trend has evolved into what’s known as “humanmaxxing,” sparking a bigger question: How far can people go to optimize the human body?
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While there is no single definition of humanmaxxing, the trend generally refers to efforts to optimize health, performance and longevity through a combination of lifestyle habits, health tracking, supplements and, in some cases, more experimental interventions.
While there is no single definition of humanmaxxing, the trend generally refers to efforts to optimize health, performance and longevity through a combination of lifestyle habits, health tracking, supplements and, in some cases, more experimental interventions. (iStock)
For some, the movement begins with biohacking. According to Dave Asprey, a Texas-based wellness expert who refers to himself as the “father of biohacking,” optimizing your body starts with changing your environment.
Asprey has defined biohacking as “the art and science of changing the environment around you or inside you so that you have full control of your own biology.”
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His public advice focuses on boosting cellular energy through everyday choices like intermittent fasting, high-fat diets, red-light therapy and supplement routines.
“My goal right now is 180 years, because I’m doing something about it now instead of waiting,” he once said.
Clinical experts warn that extreme self-experimentation skips the rigorous safety checks that typical medical science requires. (iStock)
Others have embraced a more data-driven approach. Tech entrepreneur Bryan Johnson, creator of the multimillion-dollar longevity project Blueprint in Los Angeles, argues that optimizing the body means removing human error from health decisions and instead relying on medical data.
“Methodically, we sought to build an algorithm with science and data that could better care for me than I can myself,” Johnson wrote on his website. “My mind did not have the authority to override the algorithm.”
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Johnson’s routine involves tracking hundreds of health metrics, eating a precisely measured diet, taking dozens of supplements, and undergoing advanced medical treatments in an effort to reduce his biological age.
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At the far end of the spectrum are those investing in technologies aimed at pushing the limits of human performance.
London-based tech investor Christian Angermayer recently described humanmaxxing as a strategy toward human maximization.
Tech entrepreneur Bryan Johnson, creator of the multimillion-dollar longevity project Blueprint, argues that optimizing the body means removing human error from health decisions and instead relying on medical data. (iStock)
“I don’t think we should become something different, because I think humans are awesome, but I think we can maximize the potential [that] is already in us,” he said in an interview with The New York Times.
Angermayer’s investment firm, Apeiron Investment Group, focuses on technologies intended to help people “live longer, healthier and more fulfilling lives.” He also founded atai Life Sciences, a biotechnology company that develops psychedelic treatments for mental health conditions that are currently being evaluated in clinical trials.
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As interest in humanmaxxing grows, mainstream health experts urge consumers to separate evidence-based wellness practices from experimental interventions.
Public guidance from the National Institute on Aging notes that while some anti-aging therapies have shown promise in laboratory research, there is not yet sufficient evidence that they can safely extend human life.
As interest in humanmaxxing grows, mainstream health experts urge consumers to separate evidence-based wellness practices from experimental interventions. (iStock)
Clinical experts also caution that extreme self-experimentation can bypass the rigorous safety standards applied to conventional medical treatments.
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According to the Endocrine Society, taking substances such as testosterone or growth hormone without a medical need can lead to serious health risks, including cardiovascular complications and long-term disruption of the body’s chemical balance.
While many humanmaxxing habits overlap with standard healthy lifestyle practices, experts say consumers should be cautious of expensive or experimental interventions that promise dramatic anti-aging or longevity benefits without strong scientific evidence.
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A new test could make it easier to detect high-risk prostate cancer cases earlier.
The blood test, called Stockholm3, is showing promise in clinical trials, beating out the traditional, standard prostate-specific antigen (PSA) test.
In a new study published in the Annals of Internal Medicine, researchers from the Karolinska Institutet in Sweden studied the test’s efficacy in more than 12,000 men — mostly Swedish or European — aged 50 to 74.
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All participants were tested with PSA and Stockholm3 and were followed for two years. During the follow-up period, 443 men were diagnosed with aggressive prostate cancer.
Stockholm3 detected 90% of aggressive prostate cancer cases compared to 74% for PSA tests.
Stockholm3 detected 90% of aggressive prostate cancer cases compared to 74% for PSA tests. (iStock)
Stockholm3 missed “significantly fewer” serious cancer cases than PSA. The number of men incorrectly classified as high-risk was similar across both tests, according to a press release.
Thorgerdur Palsdottir, a researcher at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, wrote in a statement that one of the major challenges in prostate cancer is being able to identify the cases that are “truly dangerous.”
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“Our results show that Stockholm3 identifies significantly more aggressive cancer cases than PSA without increasing the number of unnecessary follow-ups,” she said.
“These results point toward a potential change in how prostate cancer screening can be conducted,” the researcher added. “A more precise blood test could enable earlier detection of aggressive disease while reducing the number of unnecessary follow-up examinations and procedures.”
“A more precise blood test could enable earlier detection of aggressive disease while reducing the number of unnecessary follow-up examinations and procedures,” a researcher commented. (iStock)
Study co-author Hari Vigneswaran, chief medical officer of Stockholm3-maker A3P Biomedical, commented on these “promising” findings in an interview with Fox News Digital.
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He confirmed that the PSA has been the standard for prostate cancer screening since the 1990s despite its “well-documented limitations.”
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“It leads to invasive and costly follow-up testing, contributes to over-diagnosis of non-aggressive cancers and, most importantly, it misses a substantial share of aggressive disease,” Vigneswaran said.
When aggressive prostate cancer is found while still confined in the prostate, the five-year survival is close to 100%. (iStock)
When aggressive prostate cancer is found while still confined in the prostate, the five-year survival rate is close to 100%, which highlights the importance of early detection, according to the doctor.
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Data from the National Cancer Institute’s SEER database show that metastatic prostate cancer has risen over the past decade, suggesting that “we have not improved early detection of the aggressive, curable disease that screening is meant to catch,” Vigneswaran said.
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“The goal of screening is to find the cancers that need treatment while they are still curable, without raising the number of men who screen positive but don’t have aggressive disease,” he said.
Stockholm3 could reduce the need for unnecessary MRIs and biopsies, according to the researcher. (Getty Images)
Stockholm3 could reduce the need for unnecessary MRIs and biopsies, according to the researcher.
The findings did have some limitations. Stockholm3 is an investigational device and is not available for sale in the U.S., Vigneswaran noted.
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The test estimates a man’s risk of aggressive prostate cancer, but a biopsy remains the gold standard for confirming the disease.
The company plans to seek FDA approval to use the test for routine screening and will “generate the evidence needed to support that pathway, including U.S. data,” Vigneswaran said.
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