In the current dining landscape, San Diego restaurants face challenges like the rising cost of goods, labor shortages, and evolving customer expectations. Everything from longtime city institutions to newer places unable to find their footing can succumb to a combination of obstacles, although San Diego restaurateurs and chefs remain resilient — just check out Eater’s hot new restaurants map for proof. This column keeps track of all the closures you may have missed.
San Diego, CA
Illumina and the San Diego Zoo are sequencing koala genomes to investigate disease
Two world-class institutions that call San Diego home have joined forces on an investigation into the DNA of koalas.
The San Diego Zoo Wildlife Alliance and DNA-sequencing giant Illumina are examining the genetic information of nearly 100 koalas spanning 30 years to get a better understanding of koala retrovirus, or KoRV.
Scientists suspect through growing evidence that certain variants of koala retrovirus—all koalas carry some form of it—are associated with common diseases and health issues they have, such as leukemia, lymphoma and deadly fungal infections.
KoRV is baked into the genes of koalas and gets passed along to the next generation. This boat load of genetic data will help researchers examine patterns of how KoRV is getting integrated into koala genes. In turn, having a better understanding of KoRV will help inform conservation plans for koalas in the wild and in human care.
Dr. Cora Singleton, senior veterinarian at the San Diego Zoo Wildlife Alliance, works primarily with marsupials, including koalas. Singleton has cared for koalas for years and witnessed them struggle with the health effects of KoRV.
In order to sequence the genome, the San Diego Zoo used samples from 91 current koalas living at the zoo as well as samples from the frozen zoo—a bank of living cells—going back to the 1970s. These samples were then sent to Illumina’s laboratory in San Diego, where researchers extracted the DNA to prepare it for sequencing in their machines. Those sequencing instruments break the DNA down into the basic alphabet that makes up all genetic information.
Ashley Van Zeeland, vice president of corporate development at Illumina, said there is a lot less known about the koala genome than the human genome. That mass amount of data was then sent to collaborators in other countries, who are now studying the koala genomes.
“(They) take the data that our instruments generate and put it together into kind of the full picture of that species,” Van Zeeland said.
Van Zeeland, who has worked in genomics for two decades, explained the unique offering of this dataset is that it pairs generations of genetic data alongside meticulously documented medical records. For instance, researchers can examine the cause of death for a koala and its parents to see if there’s a connection.
Researchers are looking for patterns of where KoRV has inserted itself into the koala’s DNA because it’s not entering at the same spot for every koala. More specifically, researchers are comparing the patterns of how KoRV integrated into koala genes in a way that may be associated with certain diseases.
Van Zeeland explained that looking at where KoRV inserted itself in the genome may give researchers an idea of which genes might be disrupted, turned on or off in the koala and the resulting effect on their health.
Having that knowledge of which integration patterns correlate with certain adverse health effects could inform how conservationists pair up koala populations for reproduction. As koalas already face pressures from climate change and a disappearing habitat in the wild, this would tackle one more stressor on the endangered population.
While the koala genome had already been sequenced previously, the scale of this project wasn’t feasible even a few years ago, explained Singleton.
“One of the questions everybody always said from a research perspective: ‘wouldn’t it be great if we could see what’s going on in the genome?’ But for many, many years it was very expensive and very labor intensive,” Singleton said.
Illumina has been focused on getting the cost of sequencing the genome down so this kind of technology is more accessible and applicable for researchers. Van Zeeland said that in 2015 it cost roughly $1,000 to $2,000 to sequence a genome, but now that cost is down to about $200 using the latest technology. (Illumina’s work on the project is through its Illumina iConserve initiative, which focuses on environmental and wildlife conservation.)
Singleton characterizes this project as a career highlight to be a part of a network of collaborators trying to solve the same puzzle. While it’s been years in the making, she always knew “there was something special in there that we had to uncover at the right time and the right place.”
“It’s the moment for genetics to take off in the world of conservation,” Singleton said.
The effort to compile and analyze a database of the North American koala population will be the largest koala pedigree genomic database in the world. The project spans continents and is also aided by the University of Sydney, Australian Museum Research Institute, University of Nottingham, Leibniz Institute for Zoo and Wildlife Research and ZooParc de Beauval.
2024 The San Diego Union-Tribune. Distributed by Tribune Content Agency, LLC.
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SAN DIEGO (FOX 5/KUSI) — Fans are embracing every remaining moment rallying behind San Diego’s professional indoor women’s volleyball team as it prepares to fold after this season.
One final home crowd lifted the team Thursday night at Viejas Arena before they take their shot at the MLV playoffs and the uncertainty that follows.
“It’s sad. I’m going to miss them for sure,” said local fan Jordan Haskel with her mom by her side. “It’s our thing to come out here together,” said her mother, Babs Symonds.
The team will not be returning for the upcoming season fans are coming to terms with the announcement.
“My heart is broken now when I got the news today that they’re not going to be here next year,” said Danny Jackson.
Owner Gary Jacobs wanted to pause the team in 2027 to pursue a long-term plan, but the league rejected the idea, so the team will shut down while the league searches for new investors.
“You have to have pretty deep pockets to support a team and to support a team you got to have supporters to come out and buy tickets, and you got to be in the stands to yell for them. Last week, I made a comment to my wife I said, God, I wish we had more fans in here,” said Jackson.
It’s not the first time San Diego sports fans have faced losing a team.
“We saw that with the Chargers. We saw that with the Loyals. Unfortunately, sometimes it’s outside of our control,” said Desiree Morales.
Volleyball shaped Morales by instilling discipline and teamwork – values she hopes to pass on to her niece through the Mojo.
“I want them to stay so I can come here every day to see them play,” said Morales’ niece, Isabella.
One thing is for sure, the community the team has built will stay, waiting patiently for what comes next.
“Whether you’re rooting just for San Diego or the team itself or the sport itself you just have to do it,” said Morales.
Major League Volleyball released a statement that reads in part, “San Diego remains one of the most vibrant volleyball communities in the country, and we believe strongly in its long-term potential at the professional level. We are actively exploring strategies for the market, building on the momentum established by the Mojo.”
Del Mar— Cucina Enoteca closed its doors in mid-March after nearly 12 years in the Flower Hill Promenade. In a statement shared with Eater, Urban Kitchen Group owner Tracy Borkum attributed the closure to “substantially increased property taxes.” The hospitality group’s other restaurants, including Cucina Urbana, Artifact and Craft Café at Mingei Museum, The Kitchen at MCASD, Gold Finch, and Morena Provisions, remain open while Cucina Enoteca searches for a new location in North County.
Carmel Valley— Taiwanese shaved ice dessert shop Icekimo shuttered its location in the Del Mar Highlands Town Center. “It was a great location, but the operating expenses were too high. Such a tough time for many businesses,” says owner Robert Yang. Icekimo also shuttered its Eastlake outpost. The flagship location in the Convoy District remains open. In April, a new Icekimo food truck will be available for booking via Instagram.
Kearny Mesa— Sizzling House and Noodles closed its doors after being open for just two years in the Convoy District. One of the first restaurants to open in Plaza del Sol, which was damaged in a 2020 fire, the Asian restaurant served seared marinated proteins on hot platters. Mr. Lin, the restaurant’s owner, tells Eater he sold the business to Urban Matcha, a tea shop that’s expanding from Las Vegas. While he still owns Tasty Pot in Mira Mesa, he hasn’t decided if he’ll open another restaurant. “We’re going to wait to see what the economy does,” Lin says.
North Park— After operating for more than three years at a corner spot in North Park, Patisserie Melanie has closed its doors, according to the San Diego Union-Tribune. At the bakery, owner and Le Cordon Bleu-trained chef Melanie Dunn served croissants, kouign-amann, and quiches that she learned to make in Paris while transitioning from a career as a high school teacher to pastry chef.
Sorrento Valley— Decade-old Chinese restaurant Ma-Dasao closed its doors and rebranded as Shanghai Cuisine; the restaurant’s ownership remains unchanged. Shanghai Cuisine offers all-you-can-eat deals and weekday lunch combos, along with dim sum, in a cafeteria-style setting. Select dishes from the previous Ma-Dasao menu, such as Taiwanese beef noodle soup, are also available.
University Town Center— Rick Bayless’s Mexican restaurant, Red O’s, chose not to renew its lease in the complex across the street from Westfield UTC Mall, according to the San Diego Union-Tribune. The other three Red O outposts in Newport Beach, Westlake Village, and Santa Monica remain open. Plans to tear down the buildings to create new apartment complexes are expected to begin this spring.
Oceanside— After 18 years of serving morning buns, bear claws, and sweet and savory croissants in Oceanside, Petite Madeleine closed its doors on March 15. The bakery announced its closure with a statement shared on Instagram.
Gaslamp Quarter— San Diego Dining Group steakhouse Butcher’s Cut shuttered its doors in January after nearly six years. Romanissimo, operated by the same hospitality group as Butcher’s Cut, took over the space. The Roman trattoria first opened in early 2025 at a neighboring Gaslamp Quarter location with a menu of pastas made in-house, burrata caprese, and bone-in rib-eye.
East County News Service
April 29, 2026 (San Diego County) — The U.S. Postal Service will carry more than just mail Saturday, May 9 during the 34th annual Stamp Out Hunger Food Drive.
Recognized as the largest single-day food collection effort in the United States, the event mobilizes the National Association of Letter Carriers and the Jacobs & Cushman San Diego Food Bank in replenishing local food pantry shelves before summer.
The drive comes at a pivotal moment for the region.
As the school year draws to a close, many children lose access to the daily free or reduced-price meal programs offered by school districts. The summer gap, combined with the sustained pressure of high local living costs, has kept the demand for food assistance at near-record levels.
Last year, the community’s response was massive, with residents donating nearly 127,000 pounds of food along local mail routes.
The logistics of the drive are designed for maximum convenience. To donate, San Diego County residents are asked to place a sturdy bag containing non-perishable food items next to their mailbox before their letter carrier arrives on Saturday.
Letter carriers will collect these donations and take them to local hubs where volunteers and Food Bank staff will sort the haul. The food is then moved to the Food Bank’s primary warehouse in the Miramar area before being distributed to more than 450 nonprofit partners. (Partners including soup kitchens, shelters, and faith-based pantries across the county.)
The Food Bank and more
The San Diego Food Bank has been a fixture of the community since 1977, growing from a small grassroots operation into the county’s primary hunger-relief engine. While the organization rescues millions of pounds of fresh produce and retail leftovers annually, the Stamp Out Hunger drive provides shelf-stable items essential for long-term food security.
Organizers have identified several “most-needed” items that provide the highest nutritional value for families in crisis. These include canned meats and fish, such as tuna and chicken; canned vegetables and fruits; and canned soups, and stews. High-demand pantry staples like oatmeal, boxes of cereal, rice and jars of peanut butter are also high on the priority list.
While the letter carriers handle the heavy lifting on the routes, a massive volunteer effort will be underway at several key processing locations across the city. Between 3 and 6 p.m., teams will be stationed at the Encanto, Grantville and Scripps Ranch post offices, as well as the Food Bank’s main Miramar Warehouse, to manage the influx of goods.
For the NALC, this drive represents a decades-long commitment to the communities they walk every day. By leveraging the existing infrastructure of the postal service, the drive reaches neighborhoods that might otherwise be disconnected from traditional donation centers.
For more information, visit sandiegofoodbank.org/stamp-out-hunger.
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