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Cancer’s New Face: Younger and Female

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Cancer’s New Face: Younger and Female

More Americans are surviving cancer, but the disease is striking young and middle-aged adults and women more frequently, the American Cancer Society reported on Thursday.

And despite overall improvements in survival, Black and Native Americans are dying of some cancers at rates two to three times higher than those among white Americans.

These trends represent a marked change for an illness that has long been considered a disease of aging, and which used to affect far more men than women.

The shifts reflect declines in smoking-related cancers and prostate cancer among older men and a disconcerting rise in cancer in people born since the 1950s.

Cancer is the second leading cause of death in the United States, but the leading cause among Americans under 85. The new report projects that some 2,041,910 new cases will occur this year and that 618,120 Americans will die of the disease.

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Six of the 10 most common cancers are on the rise, including cancers of the breast and the uterus. Also on the rise are colorectal cancers among people under 65, as well as prostate cancer, melanoma and pancreatic cancer.

“These unfavorable trends are tipped toward women,” said Rebecca L. Seigel, an epidemiologist with the American Cancer Society and the report’s first author.

“Of all the cancers that are increasing, some are increasing in men, but it’s lopsided — more of this increase is happening in women.”

Women are also being diagnosed at younger ages. Cancer rates are rising among women under 50 (so-called early-onset cancer), as well as among women 50 to 64.

Despite increases in some early-onset cancers, like colorectal cancer and testicular cancer, “overall rates are flat in men under 50 and decreasing in those 50 to 64,” Ms. Seigel said.

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Several other troubling trends are outlined in the report. One is an increase in new cases of cervical cancer — a disease widely viewed as preventable in the United States — among women 30 to 44.

The incidence of cervical cancer has plummeted since the mid-1970s, when Pap smear screening to detect precancerous changes became widely available. But recent surveys have found many women are postponing visits to their gynecologists.

A Harris Poll survey of over 1,100 U.S. women last year found that 72 percent said they had put off a visit with their doctor that would have included screening; half said they didn’t know how frequently they should be screened for cervical cancer.

(The current recommendation is a bit complicated: Get a Pap smear every three years starting at age 21, or a combined Pap smear and test for the human papillomavirus, which can cause cervical cancer, every five years.)

Another disturbing trend started in 2021 when, for the first time, lung cancer incidence in women under 65 surpassed the incidence in men: 15.7 cases per 100,000 women under 65, compared with 15.4 per 100,000 in men.

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Lung cancer has been declining over the past decade, but it has decreased more rapidly in men. Women took up smoking later than men and took longer to quit.

There have also been upticks in smoking in people who were born after 1965, the year after the surgeon general first warned that cigarettes cause cancer.

Smoking continues to be the leading cause of preventable death in the United States, accounting for almost 500 cancer deaths daily in 2025, mostly from lung cancer, the American Cancer Society said.

“There is growing concern that e-cigarettes and vaping may contribute to this burden in the future, given their carcinogenic potential and wide popularity,” the report said.

Breast cancer rates have also been inching up for many years, increasing by about 1 percent a year between 2012 and 2021. The sharpest rise has been seen in women under 50, and there have been steep increases among Hispanic American, Asian American and Pacific Islander women.

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The increases are driven by detection of localized tumors and certain cancers fueled by hormones.

Some of the rise results from changing fertility patterns. Childbearing and breastfeeding protect against breast cancer, but more American women are postponing childbirth — or are choosing not to bear children at all.

Other risk factors include genetics, family history and heavy drinking — a habit that has increased in women under 50. In older women, excess body weight may play a role in cancer risk.

Uterine cancer is the only cancer for which survival has actually decreased over the past 40 years, the A.C.S. said.

Death rates are also rising for liver cancer among women, and for cancers of the oral cavity for both sexes.

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Pancreatic cancer has been increasing in incidence among both men and women for decades. It is now the third leading cause of cancer death. As with many other cancers, obesity is believed to contribute.

Little progress has been made in the understanding and treatment of pancreatic cancer. Death rates have been rising since record-keeping started, rising to 13 per 100,000 in men and 10 per 100,000 in women today, up from about five per 100,000 in both men and women in the 1930s.

The lack of progress has frustrated many scientists and physicians. The cancer is often fairly advanced when diagnosed, and the five-year survival rate is only 13 percent.

“We need to make progress in specifically understanding what’s driving pancreatic cancers to grow, what treatment will then stave off these cancers, what can prevent it in the first place, and how we can screen for it early,” said Dr. Amy Abernathy, an oncologist who co-founded Highlander Health, which focuses on accelerating clinical research.

Some experts are beginning to acknowledge that environmental exposures may be contributing to early-onset cancer, in addition to the usual suspects: lifestyle, genetics and family history.

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“I think that the rise in not just one but a variety of cancers in younger people, particularly in young women, suggests there is something broader going on than variations in individual genetics or population genetics,” said Neil Iyengar, an oncologist at Memorial Sloan Kettering Cancer Center.

“It strongly points to the possibility that environmental exposures and our lifestyles in the U.S. are contributing to the rise of cancers in younger people.”

Public health efforts aimed at reducing risky lifestyle behaviors have focused on people at higher risk and at older Americans, who still bear the brunt of cancer’s burden, he noted.

But the risk factors in young people may be different.

Emerging research hints that maintaining regular sleeping patterns, for example, may also help to prevent cancer, he said.

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Lifestyle and behavioral changes can reduce the risk for many cancers, Ms. Siegel said.

“I don’t think people realize how much control they have over their cancer risk,” she said. “There’s so much we can all do. Don’t smoke is the most important.”

Among the others: Maintaining a healthy body weight; not consuming alcohol or consuming in moderation; eating a diet high in fruits and vegetables, and low in red and processed meat; physical activity; and regular cancer screenings.

“There are all these things you can do, but they’re individual choices, so just pick one that you can focus on,” she said. “Small changes can make a difference.”

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The share of Americans medically obese is projected to rise to almost 50% by 2035

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The share of Americans medically obese is projected to rise to almost 50% by 2035

On Wednesday, a new study published in JAMA by researchers at the University of Washington in Seattle projected that by 2035, nearly half of all American adults, about 126 million individuals, will be living with obesity. The study draws on data from more than 11 million participants via the U.S. Centers for Disease Control and Prevention’s National Health and Nutrition Examination and Behavioral Risk Factor Surveillance System, and from the independent Gallup Daily Survey.

The projections show a striking increase in the prevalence of obesity over the past few decades in the U.S. In 1990, only 19.3% of U.S. adults were obese, according to the study. That figure more than doubled to 42.5% by 2022, and is forecast to reach 46.9% by 2035.

The study highlights significant disparities across states, ages, and racial and ethnic groups. While every state is expected to see increases, the sharpest rises are projected for Midwestern and Southern states.

For example, nationwide, by 2035, the study projects that 60% (11.5 million adults) of Black women and 54% (14.5 million) of Latino women will suffer from obesity when compared with 47% (36.5 million) of white women. Similarly, 48% (13.2 million) of Latino men will suffer from the disease compared with 45% (34.4 million) of white men and 43% (7.61 million) of Black men.

The findings say California will see similar trends in gender and racial disparities. The study projects that by 2035, obesity rates among Latino and Black women in California will reach nearly 60%, compared with nearly 40% for their white counterparts. Additionally, Latino men in California could see rates over 50%, compared with nearly 40% for their white counterparts.

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“These numbers are not surprising, given the systemic inequalities that exist,” in many California cities, said Dr. Amanda Velazquez, director of obesity medicine at Cedars-Sinai Hospital, pointing to economic instability, chronic stress and the car-dependency of Los Angeles and other California metro areas. “There are challenges for access to nutritious foods, depending on where you’re at in the city,” Velazquez said. ”There’s also disparities in the access to healthcare, especially to treatment for obesity.”

That’s recently become more of a challenge, since changes in Medi-Cal plans that went into effect at the beginning of this year mean obesity medication and treatment are no longer covered for hundreds of thousands of low-income Californians. “To take that away is devastating,” said Velazquez.

Despite these disparities, California is projected to fare better than most other states, with its rates of obesity growing more slowly than the national average.

“There are statewide and local policies that influence food, nutrition and social determinants of health for individuals,” said Velazquez.

Church pointed to measures such as SB 12 and SB 677, passed in the mid 2000s, which set strict nutritional standards for schools, existing menu labeling laws at both the state and federal levels requiring restaurants to provide nutritional facts on menu items, and cities like Berkeley and Oakland imposing local soda taxes as key local and statewide initiatives to keep obesity at bay.

To keep up this momentum, both doctors stressed that California must continue to strengthen school nutrition standards, expand transportation infrastructure that encourages walking instead of driving, maintain and expand economic disincentives to unhealthy foods, such as beverage taxes, and address food deserts by incentivizing new grocery stores and farmers’ markets in underserved neighborhoods.

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Future efforts, Church says, should prioritize the Black and Latino populations identified by the study as most affected.

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Pediatricians urge Americans to stick with previous vaccine schedule despite CDC’s changes

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Pediatricians urge Americans to stick with previous vaccine schedule despite CDC’s changes

For decades, the American Academy of Pediatrics and the U.S. Centers for Disease Control and Prevention spoke with a single voice when advising the nation’s families on when to vaccinate their children.

Since 1995, the two organizations worked together to publish a single vaccine schedule for parents and healthcare providers that clearly laid out which vaccines children should get and exactly when they should get them.

Today, that united front has fractured. This month, the Department of Health and Human Services announced drastic changes to the CDC’s vaccine schedule, slashing the number of diseases that it recommends U.S. children be routinely vaccinated against to 11 from 17. That follows the CDC’s decision last year to reverse its recommendation that all kids get the COVID-19 vaccine.

On Monday, the AAP released its own immunization guidelines, which now look very different from the federal government’s. The organization, which represents most of the nation’s primary care and specialty doctors for children, recommends that children continue to be routinely vaccinated against 18 diseases, just as the CDC did before Robert F. Kennedy Jr. took over the nation’s health agencies.

Endorsed by a dozen medical groups, the AAP schedule is far and away the preferred version for most healthcare practitioners. California’s public health department recommends that families and physicians follow the AAP schedule.

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“As there is a lot of confusion going on with the constant new recommendations coming out of the federal government, it is important that we have a stable, trusted, evidence-based immunization schedule to follow and that’s the AAP schedule,” said Dr. Pia Pannaraj, a member of AAP’s infectious disease committee and professor of pediatrics at UC San Diego.

Both schedules recommend that all children be vaccinated against measles, mumps, rubella, polio, pertussis, tetanus, diphtheria, Haemophilus influenzae type B (Hib), pneumococcal disease, human papillomavirus (HPV) and varicella (better known as chickenpox).

AAP urges families to also routinely vaccinate their kids against hepatitis A and B, COVID-19, rotavirus, flu, meningococcal disease and respiratory syncytial virus (RSV).

The CDC, on the other hand, now says these shots are optional for most kids, though it still recommends them for those in certain high-risk groups.

The schedules also vary in the recommended timing of certain shots. AAP advises that children get two doses of HPV vaccine starting at ages 9 to12, while the CDC recommends one dose at age 11 or 12. The AAP advocates starting the vaccine sooner, as younger immune systems produce more antibodies. While several recent studies found that a single dose of the vaccine confers as much protection as two, there is no single-dose HPV vaccine licensed in the U.S. yet.

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The pediatricians’ group also continues to recommend the long-standing practice of a single shot combining the measles, mumps and rubella (MMR) and varicella vaccines in order to limit the number of jabs children get. In September, a key CDC advisory panel stocked with hand-picked Kennedy appointees recommended that the MMR and varicella vaccines be given as separate shots, a move that confounded public health experts for its seeming lack of scientific basis.

The AAP is one of several medical groups suing HHS. The AAP’s suit describes as “arbitrary and capricious” Kennedy’s alterations to the nation’s vaccine policy, most of which have been made without the thorough scientific review that previously preceded changes.

Days before AAP released its new guidelines, it was hit with a lawsuit from Children’s Health Defense, the anti-vaccine group Kennedy founded and previously led, alleging that its vaccine guidance over the years amounted to a form of racketeering.

The CDC’s efforts to collect the data that typically inform public health policy have noticeably slowed under Kennedy’s leadership at HHS. A review published Monday found that of 82 CDC databases previously updated at least once a month, 38 had unexplained interruptions, with most of those pauses lasting six months or longer. Nearly 90% of the paused databases included vaccination information.

“The evidence is damning: The administration’s anti-vaccine stance has interrupted the reliable flow of the data we need to keep Americans safe from preventable infections,” Dr. Jeanne Marrazzo wrote in an editorial for Annals of Internal Medicine, a scientific journal. Marrazzo, an infectious disease specialist, was fired last year as head of the National Institute of Allergy and Infectious Diseases after speaking out against the administration’s public health policies.

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‘We’re not going away’: Rob Caughlan, fierce defender of the coastline and Surfrider leader, dies at the age of 82

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‘We’re not going away’: Rob Caughlan, fierce defender of the coastline and Surfrider leader, dies at the age of 82

Known by friends and colleagues as a “planetary patriot,” a “happy warrior” and the “Golden State Eco-Warrior,” Rob Caughlan, a political operative, savvy public relations specialist and one of the early leaders of the Surfrider Foundation, died at his home in San Mateo, on Jan. 17. He was 82.

His wife of nearly 62 years, Diana, died four days earlier, from lung cancer.

Environmentalists, political operatives and friends responded to his death with grief but also joy as they recalled his passion, talent and sense of humor — and his drive not only to make the world a better place, but to have fun doing it.

“He’d always say that the real winner in a surfing contest was the guy who had the most fun,” said Lennie Roberts, a conservationist in San Mateo County and longtime friend of Caughlan’s. “He was true to that. It’s the way he lived.”

“When he walked into a room, he’d have a big smile on his face. He was a great — a gifted — people person,” said Dan Young, one of the original five founders of the Surfrider Foundation. The organization was cobbled together in the early 1980s by a group of Southern California surfers who felt called to protect the coastline — and their waves.

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They also wanted to dispel the stereotype that surfers are lackadaisical stoners — and show the world that surfers could get organized and fight for just causes, said Roberts, citing Caughlan’s 2020 memoir, “The Surfer in the White House and Other Salty Yarns.”

Before joining Surfrider in 1986, Caughlan was a political operative who worked as an environmental adviser in the Carter administration. According to Warner Chabot, an old friend and recently retired executive director of the an Francisco Estuary Institute, Caughlan got his start during the early 1970s when he and his friend, David Oke, formed the Sam Ervin Fan Club, which supported the Southern senator’s efforts to lead the Watergate investigation of President Nixon.

According to Chabot, Caughlan organized the printing of T-shirts with Ervin’s face on them, underneath the text “I Trust Uncle Sam.”

“He was an early social influencer — par extraordinaire,” he said.

Glenn Hening, a surfer, former Jet Propulsion Laboratory space software engineer and another original founder of the Surfrider Foundation, said one of the group’s initial fights was against the city of Malibu, which in the early 1980s was periodically digging up sand in the lagoon right offshore and destroying the waves at one of their favorite surf spots.

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According to Hening, it was Caughlin’s unique ability to persuade and charm politicians and donors that put Surfrider’s efforts on the map.

Caughlan served as the foundation’s president from 1986 to 1992.

The foundation grabbed the national spotlight in 1989 when it went after two large paper mills in Humboldt Bay that were discharging toxic wastewater into an excellent surfspot in Northern California. The foundation took aim and in 1991 filed suit alongside the U.S. Environmental Protection Agency; the paper mills settled for $5.8 million.

Hening said the victory would never have happened without Caughlan.

The mills had tried to brush off the suit by offering a donation to the foundation, Hening said. But Caughlan and Mark Massara — an environmental lawyer with the organization — rebuffed the gesture.

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“The paper mill guys said, ‘Well, what can we do here? How can we make this go away?’” said Hening, recalling the conversation. “And Rob said, ‘It’s not going to go away. We’re not going away. We’re surfers.”

Roberts said Caughlan’s legacy can be felt by anyone who has ever spent time on the San Mateo County coastline. In the 1980s, the two spearheaded a successful ballot measure still protects the coast from non-agricultural development and ensured access to the beaches and bluffs. It also prohibits onshore oil facilities for off-shore facilities.

The two also worked on a county measure that led to the development of the Devil’s Slide tunnels on Highway 1 between Pacifica and Montara, designed to make that formerly treacherous path safer for travelers.

The state had wanted to build a six-lane highway over the steep hills in the area. “It would have been dangerous because of the steep slopes, and it would be going up into the fog bank and then back down out of the fog. So it was inherently dangerous,” Roberts said.

Chad Nelsen, the current president of the Surfrider Foundation, said he was first drawn into Caughlan’s orbit in 2010 when Surfrider got involved with a lawsuit pertaining to a beach in San Mateo County. Silicon Valley venture capitalist Vinod Khosla purchased 53 acres of Northern California coastline for $32.5 million and closed off access to the public — including a popular stretch known as Martin’s Beach — so Surfrider sued.

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Nelsen said that although Caughlan had left the organization about 20 years before, he reappeared with a “sort of unbridled enthusiasm and commitment to the cause,” and the organization ultimately prevailed — the public can once again access the beach “thanks to ‘Birdlegs.’”

Birdlegs was Caughlan’s nickname, and according to Nelsen, it was probably coined in the 1970s by his fellow surfers.

“He had notoriously spindly legs, I guess,” Nelsen said.

Robert Willis Caughlan was born in Alliance, Ohio, on Feb. 27, 1943. His father, who was a parachute instructor with the U.S. Army, died when Caughlan was 4. In 1950, Caughlan moved with his mother and younger brother to San Mateo, where he saw the ocean for the first time.

He rode his his first wave in 1959, at the age of 16, from the breakwater at Half Moon Bay.

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