Science
Cancer’s New Face: Younger and Female
More Americans are surviving cancer, but the disease is striking young and middle-aged adults and women more frequently, the American Cancer Society reported on Thursday.
And despite overall improvements in survival, Black and Native Americans are dying of some cancers at rates two to three times higher than those among white Americans.
These trends represent a marked change for an illness that has long been considered a disease of aging, and which used to affect far more men than women.
The shifts reflect declines in smoking-related cancers and prostate cancer among older men and a disconcerting rise in cancer in people born since the 1950s.
Cancer is the second leading cause of death in the United States, but the leading cause among Americans under 85. The new report projects that some 2,041,910 new cases will occur this year and that 618,120 Americans will die of the disease.
Six of the 10 most common cancers are on the rise, including cancers of the breast and the uterus. Also on the rise are colorectal cancers among people under 65, as well as prostate cancer, melanoma and pancreatic cancer.
“These unfavorable trends are tipped toward women,” said Rebecca L. Seigel, an epidemiologist with the American Cancer Society and the report’s first author.
“Of all the cancers that are increasing, some are increasing in men, but it’s lopsided — more of this increase is happening in women.”
Women are also being diagnosed at younger ages. Cancer rates are rising among women under 50 (so-called early-onset cancer), as well as among women 50 to 64.
Despite increases in some early-onset cancers, like colorectal cancer and testicular cancer, “overall rates are flat in men under 50 and decreasing in those 50 to 64,” Ms. Seigel said.
Several other troubling trends are outlined in the report. One is an increase in new cases of cervical cancer — a disease widely viewed as preventable in the United States — among women 30 to 44.
The incidence of cervical cancer has plummeted since the mid-1970s, when Pap smear screening to detect precancerous changes became widely available. But recent surveys have found many women are postponing visits to their gynecologists.
A Harris Poll survey of over 1,100 U.S. women last year found that 72 percent said they had put off a visit with their doctor that would have included screening; half said they didn’t know how frequently they should be screened for cervical cancer.
(The current recommendation is a bit complicated: Get a Pap smear every three years starting at age 21, or a combined Pap smear and test for the human papillomavirus, which can cause cervical cancer, every five years.)
Another disturbing trend started in 2021 when, for the first time, lung cancer incidence in women under 65 surpassed the incidence in men: 15.7 cases per 100,000 women under 65, compared with 15.4 per 100,000 in men.
Lung cancer has been declining over the past decade, but it has decreased more rapidly in men. Women took up smoking later than men and took longer to quit.
There have also been upticks in smoking in people who were born after 1965, the year after the surgeon general first warned that cigarettes cause cancer.
Smoking continues to be the leading cause of preventable death in the United States, accounting for almost 500 cancer deaths daily in 2025, mostly from lung cancer, the American Cancer Society said.
“There is growing concern that e-cigarettes and vaping may contribute to this burden in the future, given their carcinogenic potential and wide popularity,” the report said.
Breast cancer rates have also been inching up for many years, increasing by about 1 percent a year between 2012 and 2021. The sharpest rise has been seen in women under 50, and there have been steep increases among Hispanic American, Asian American and Pacific Islander women.
The increases are driven by detection of localized tumors and certain cancers fueled by hormones.
Some of the rise results from changing fertility patterns. Childbearing and breastfeeding protect against breast cancer, but more American women are postponing childbirth — or are choosing not to bear children at all.
Other risk factors include genetics, family history and heavy drinking — a habit that has increased in women under 50. In older women, excess body weight may play a role in cancer risk.
Uterine cancer is the only cancer for which survival has actually decreased over the past 40 years, the A.C.S. said.
Death rates are also rising for liver cancer among women, and for cancers of the oral cavity for both sexes.
Pancreatic cancer has been increasing in incidence among both men and women for decades. It is now the third leading cause of cancer death. As with many other cancers, obesity is believed to contribute.
Little progress has been made in the understanding and treatment of pancreatic cancer. Death rates have been rising since record-keeping started, rising to 13 per 100,000 in men and 10 per 100,000 in women today, up from about five per 100,000 in both men and women in the 1930s.
The lack of progress has frustrated many scientists and physicians. The cancer is often fairly advanced when diagnosed, and the five-year survival rate is only 13 percent.
“We need to make progress in specifically understanding what’s driving pancreatic cancers to grow, what treatment will then stave off these cancers, what can prevent it in the first place, and how we can screen for it early,” said Dr. Amy Abernathy, an oncologist who co-founded Highlander Health, which focuses on accelerating clinical research.
Some experts are beginning to acknowledge that environmental exposures may be contributing to early-onset cancer, in addition to the usual suspects: lifestyle, genetics and family history.
“I think that the rise in not just one but a variety of cancers in younger people, particularly in young women, suggests there is something broader going on than variations in individual genetics or population genetics,” said Neil Iyengar, an oncologist at Memorial Sloan Kettering Cancer Center.
“It strongly points to the possibility that environmental exposures and our lifestyles in the U.S. are contributing to the rise of cancers in younger people.”
Public health efforts aimed at reducing risky lifestyle behaviors have focused on people at higher risk and at older Americans, who still bear the brunt of cancer’s burden, he noted.
But the risk factors in young people may be different.
Emerging research hints that maintaining regular sleeping patterns, for example, may also help to prevent cancer, he said.
Lifestyle and behavioral changes can reduce the risk for many cancers, Ms. Siegel said.
“I don’t think people realize how much control they have over their cancer risk,” she said. “There’s so much we can all do. Don’t smoke is the most important.”
Among the others: Maintaining a healthy body weight; not consuming alcohol or consuming in moderation; eating a diet high in fruits and vegetables, and low in red and processed meat; physical activity; and regular cancer screenings.
“There are all these things you can do, but they’re individual choices, so just pick one that you can focus on,” she said. “Small changes can make a difference.”
Science
Flu is hitting California early. Why doctors worry this year will be especially hard on kids
Fueled by a new viral strain, flu is hitting California early — and doctors are warning they expect the season may be particularly tough on young children.
Concentrations of flu detected in wastewater have surged in the San Francisco Bay Area, and the test positivity rate is rising in Los Angeles County and Orange County, according to state and county data. Hospitalizations and emergency room visits for flu are also rising in L.A. and Orange counties.
“We are at the point now where we’re starting to see a sharp rise in flu cases. This is a few weeks earlier than we usually experience, but very much akin to what was seen in the Southern Hemisphere’s experience with flu during their winter,” said Dr. Elizabeth Hudson, regional physician director of infectious diseases at Kaiser Permanente Southern California.
At Kaiser, flu cases are primarily being seen in clinics so far, but hospitalizations typically rise after Christmas. “We expect to see the same this year, too,” Hudson said.
“The number of cases appears to be higher at an earlier time in the usual flu season than we’ve seen in years past,” she added.
Flu levels are high in San Francisco’s sewage as well as in wastewater across San José, Sunnyvale and Palo Alto, according to WastewaterSCAN and the Santa Clara County Public Health Department.
One area of concern this winter has been the rise of a relatively new flu subvariant, known as H3N2 Flu A subclade K, which appeared toward the end of summer. That was months after officials decided which strains this fall’s flu vaccine would target.
Subclade K “is causing an active, early flu season, with more cases occurring in some countries within the Northern Hemisphere,” the California Department of Public Health said.
It remains unclear whether subclade K will reduce the efficacy of this year’s flu shot. Data recently released in Britain showed this season’s vaccines were 70% to 75% effective against hospitalization for children from the flu, and 30% to 40% effective in adults, which is within expectations, the U.S. Centers for Disease Control and Prevention noted.
This suggests “that influenza vaccination remains an effective tool in preventing influenza-related hospitalizations this season,” according to the agency.
However, the intended effectiveness of the flu vaccine against symptomatic disease caused by the new subvariant remains uncertain, the World Health Organization said.
Overall, flu rates in L.A. County remain relatively low, but are on the rise. Across California, flu hospitalizations are likewise low but increasing.
On a national level, severity indicators remain low, according to the CDC.
But the experience in other nations have led some experts to worry another severe flu season could be on deck for California.
Australia’s flu season, which is seasonally opposite from California’s, came far earlier than usual, hit with record strength and was particularly hard on the nation’s children.
Japan, Taiwan and Britain have also reported early spikes to their flu seasons.
“Whether or not this season will be more severe, only time will tell,” Hudson said of California. “We know that we have a mutation … which may make the flu vaccine work less well. But the vaccine still offers excellent protection against hospitalization and death, even with the mutated strain in circulation.”
Based on what happened in the Southern Hemisphere — particularly in Australia — “we are expecting this season to have a disproportionate impact on children under the age of 10,” Hudson said.
Already, three flu-associated pediatric deaths have been reported nationally this season, including two Friday.
During the flu season that ended in September, 280 children died from flu — the most since the swine flu pandemic season of 2009-10.
Overall, the 2024-25 season was considered the worst flu season since 2017-18, and hit adults hard as well. At least 38,000 people died from the flu last season, health authorities estimate.
Only a little more than half of the children who died from flu had an underlying medical condition, and 89% of those who died were not vaccinated, according to the CDC’s National Center for Immunization and Respiratory Diseases.
Among the children who died from flu last season, the most common complications experienced before death were shock or sepsis, pneumonia, acute respiratory distress syndrome, seizures and damage to the brain.
Early diagnosis of flu can help stave off the worst by giving those who are sick time to take antiviral medications like Tamiflu. Three out of five children who died from the flu during the 2024-25 season never received antiviral medication.
Emergency warning signs of flu complications in children include trouble breathing; bluish lips or face; ribs pulling in with each breath; chest pain; severe muscle pain, in which a child may refuse to walk; dehydration, signs of which include no urine for eight hours or no tears when crying; seizures; fevers above 104 degrees that are not controlled by medication; fever or cough that improve but return or worsen; and any fever in newborns younger than 12 weeks.
Since the official start of the respiratory virus season Oct. 1, the CDC estimates there have been at least 1,900 flu-related deaths, 49,000 hospitalizations and 4.6 million illnesses nationwide.
Doctors have been urging everybody to get the flu vaccine — the CDC recommends it for everyone age 6 months and up.
But vaccination rates have been lagging. Among children age 6 months to 17 years, an estimated 40.8% had been vaccinated as of the first week of December, according to the National Immunization Survey. In the last season before the COVID-19 pandemic, flu vaccination rates were notably higher by this time of year, at 51.2%.
At the end of last flu season, only 49.8% of children and teens had been vaccinated, the survey estimated, down from the 62.4% who had gotten their shots by the end of the 2019-20 flu season.
The decline in flu vaccinations has been seen locally, too. “Notably, fewer influenza vaccines have been administered this year compared to the same period last year,” the Orange County Health Care Agency said.
It takes about two weeks for protection to build, but getting vaccinated as soon as possible before travel or seeing friends and family “helps keep you and your loved ones safer,” the L.A. County Department of Public Health said in a statement to The Times.
Science
Why California’s milk cartons may lose their coveted recycling symbol
California milk cartons may lose their coveted recycling symbol, the one with the chasing arrows, potentially threatening the existence of the ubiquitous beverage containers.
In a letter Dec. 15, Waste Management, one of the nation’s largest waste companies, told the state the company would no longer sort cartons out of the waste stream for recycling at its Sacramento facility. Instead, it will send the milk- and food-encrusted packaging to the landfill.
Marcus Nettz, Waste Management’s director of recycling for Northern California and Nevada, cited concerns from buyers and overseas regulators that cartons — even in small amounts — could contaminate valuable material, such as paper, leading them to reject the imports.
The company decision means the number of Californians with access to beverage carton recycling falls below the threshold in the state’s “Truth in Recycling” law, or Senate Bill 343.
And according to the law, that means the label has to come off.
The recycling label is critical for product and packaging companies to keep selling cartons in California as the state’s single-use packaging law goes fully into effect. That law, Senate Bill 54, calls for all single-use packaging to be recyclable or compostable by 2032. If it isn’t, it can’t be sold or distributed in the state.
The labels also provide a feel-good marketing symbol suggesting to consumers the cartons won’t end up in a landfill when they’re discarded, or find their way into the ocean where plastic debris is a large and growing problem.
On Tuesday, the state agency in charge of waste, CalRecycle, acknowledged Waste Management’s change.
In updated guidelines for the Truth in Recycling law, recycling rates for carton material have fallen below the state threshold.
It’s a setback for carton manufacturers and their customers, including soup- and juice-makers. Their trade group, the National Carton Council, has been lobbying the state, providing evidence that Waste Management’s Sacramento Recycling and Transfer Station successfully combines cartons with mixed paper and ships it to Malaysia and other Asian countries including Vietnam, proving that there is a market. The Carton Council persuaded CalRecycle to reverse a decision it made earlier this year that beverage cartons did not meet the recycling requirements of the Truth in Recycling law.
Brendon Holland, a spokesman for the trade group, said in an email that his organization is aware of Waste Management’s decision, but its understanding is that the company will now sort the cartons into their own dedicated waste stream “once a local end market is available.”
He added that even with “this temporary local adjustment,” food and beverage cartons are collected and sorted in most of California, and said this is just a “temporary end market adjustment — not a long-term shift away from historical momentum.”
In 2022, Malaysia and Vietnam banned imports of mixed paper bales — which include colored paper, newspapers, magazines and other paper products — from the U.S. because they were so often contaminated with non-paper products and plastic, such as beverage cartons. Waste Management told The Times on Dec. 5 that it has a “Certificate of Approval” by Malaysia’s customs agency to export “sorted paper material.” CalRecycle said it has no regulatory authority on “what materials may or may not be exported.”
Adding the Sacramento facility to the list of waste companies that were recycling cartons meant that the threshold required by the state had been met: More than 60% of the state’s counties had access to carton recycling.
At the time, CalRecycle’s decision to give the recycling stamp to beverage cartons was controversial. Many in the environmental, anti-plastic and no-waste sectors saw it as a sign that CalRecycle was doing the bidding of the plastic and packaging industry, as opposed to trying to rid the state of non-recyclable, polluting waste — which is not only required by law, but is something state Atty. Gen. Rob Bonta is investigating.
Others said it was a sign that the Truth in Recycling law was working: Markets were being discovered and in some cases, created, to provide recycling.
“Recyclability isn’t static, it depends on a complicated system of sorting, transportation, processing, and, ultimately, manufacturers buying the recycled material to make a new product,” said Nick Lapis, director of advocacy for Californians Against Waste.
He said this new information, which will likely remove the recycling label from the cartons, also underscores the effectiveness of the law.
“By prohibiting recyclability claims on products that don’t get recycled, SB 343 doesn’t just protect consumers. It forces manufacturers to either use recyclable materials or come to the table to work with recyclers, local governments and policymakers to develop widespread sustainable and resilient markets,” he said.
Beverage and food cartons — despite their papery appearance — are composed of layers of paper, plastic and sometimes aluminum. The sandwiched blend extends product shelf life, making it attractive to food and beverage companies.
But the companies and municipalities that receive cartons as waste say the packaging is problematic. They say recycling markets for the material are few and far between.
California, with its roughly 40 million residents, has some of the strictest waste laws in the nation. In 1989, the state passed legislation requiring cities, towns and municipalities to divert at least 50% of their residential waste away from landfills. The idea was to incentivize recycling and reuse. However an increasing number of products have since entered the commercial market and waste stream — such as single use plastics, polystyrene and beverage cartons — that have limited (if any) recycling potential, can’t be reused, and are growing in number every year.
Fines for municipalities that fail to achieve the required diversion rates can run $10,000 a day.
As a result, garbage haulers often look for creative ways to deal with the waste, including shipping trash products overseas or across the border. For years, China was the primary destination for California’s plastic, contaminated paper and other waste. But in 2018, China closed its doors to foreign garbage, so U.S. exporters began dumping their waste in smaller southeast Asian countries, including Malaysia and Vietnam.
They too have now tried to close the doors to foreign trash as reports of polluted waterways, chokingly toxic air, and illness grows — and as they struggle with inadequate infrastructure to deal with their own domestic waste.
Jan Dell, the founder and CEO of Last Beach Cleanup, released a report with the Basel Action Network, an anti-plastic organization, earlier this month showing that the Sacramento facility and other California waste companies were sending bales of carton-contaminated paper to Malaysia, Vietnam and other Asian nations.
According to export data, public records searches and photographic evidence collected by Dell and her co-authors at the Basel Action Network, more than 117,000 tons or 4,126 shipping containers worth of mixed paper bales were sent by California waste companies to Malaysia between January and July of this year.
Dell said these exports violate international law. A spokesman for Waste Management said the material they were sending was not illegal — and that they had received approval from Malaysia.
However, the Dec. 15 letter suggests they were receiving more pushback from their export markets than they’d previously disclosed.
“While certain end users maintain … that paper mills are able to process and recycle cartons,” some of them “have also shared concerns … that the inclusion of cartons … may result in rejection,” wrote Nettz.
Dell said she was “pleased” that Waste Management “stopped the illegal sortation of cartons into mixed paper bales. Now we ask them and other waste companies to stop illegally exporting mixed paper waste to countries that have banned it.”
Science
Video: Why Scientists Are Performing Brain Surgery on Monarchs
new video loaded: Why Scientists Are Performing Brain Surgery on Monarchs
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