Science
Cancer’s New Face: Younger and Female
More Americans are surviving cancer, but the disease is striking young and middle-aged adults and women more frequently, the American Cancer Society reported on Thursday.
And despite overall improvements in survival, Black and Native Americans are dying of some cancers at rates two to three times higher than those among white Americans.
These trends represent a marked change for an illness that has long been considered a disease of aging, and which used to affect far more men than women.
The shifts reflect declines in smoking-related cancers and prostate cancer among older men and a disconcerting rise in cancer in people born since the 1950s.
Cancer is the second leading cause of death in the United States, but the leading cause among Americans under 85. The new report projects that some 2,041,910 new cases will occur this year and that 618,120 Americans will die of the disease.
Six of the 10 most common cancers are on the rise, including cancers of the breast and the uterus. Also on the rise are colorectal cancers among people under 65, as well as prostate cancer, melanoma and pancreatic cancer.
“These unfavorable trends are tipped toward women,” said Rebecca L. Seigel, an epidemiologist with the American Cancer Society and the report’s first author.
“Of all the cancers that are increasing, some are increasing in men, but it’s lopsided — more of this increase is happening in women.”
Women are also being diagnosed at younger ages. Cancer rates are rising among women under 50 (so-called early-onset cancer), as well as among women 50 to 64.
Despite increases in some early-onset cancers, like colorectal cancer and testicular cancer, “overall rates are flat in men under 50 and decreasing in those 50 to 64,” Ms. Seigel said.
Several other troubling trends are outlined in the report. One is an increase in new cases of cervical cancer — a disease widely viewed as preventable in the United States — among women 30 to 44.
The incidence of cervical cancer has plummeted since the mid-1970s, when Pap smear screening to detect precancerous changes became widely available. But recent surveys have found many women are postponing visits to their gynecologists.
A Harris Poll survey of over 1,100 U.S. women last year found that 72 percent said they had put off a visit with their doctor that would have included screening; half said they didn’t know how frequently they should be screened for cervical cancer.
(The current recommendation is a bit complicated: Get a Pap smear every three years starting at age 21, or a combined Pap smear and test for the human papillomavirus, which can cause cervical cancer, every five years.)
Another disturbing trend started in 2021 when, for the first time, lung cancer incidence in women under 65 surpassed the incidence in men: 15.7 cases per 100,000 women under 65, compared with 15.4 per 100,000 in men.
Lung cancer has been declining over the past decade, but it has decreased more rapidly in men. Women took up smoking later than men and took longer to quit.
There have also been upticks in smoking in people who were born after 1965, the year after the surgeon general first warned that cigarettes cause cancer.
Smoking continues to be the leading cause of preventable death in the United States, accounting for almost 500 cancer deaths daily in 2025, mostly from lung cancer, the American Cancer Society said.
“There is growing concern that e-cigarettes and vaping may contribute to this burden in the future, given their carcinogenic potential and wide popularity,” the report said.
Breast cancer rates have also been inching up for many years, increasing by about 1 percent a year between 2012 and 2021. The sharpest rise has been seen in women under 50, and there have been steep increases among Hispanic American, Asian American and Pacific Islander women.
The increases are driven by detection of localized tumors and certain cancers fueled by hormones.
Some of the rise results from changing fertility patterns. Childbearing and breastfeeding protect against breast cancer, but more American women are postponing childbirth — or are choosing not to bear children at all.
Other risk factors include genetics, family history and heavy drinking — a habit that has increased in women under 50. In older women, excess body weight may play a role in cancer risk.
Uterine cancer is the only cancer for which survival has actually decreased over the past 40 years, the A.C.S. said.
Death rates are also rising for liver cancer among women, and for cancers of the oral cavity for both sexes.
Pancreatic cancer has been increasing in incidence among both men and women for decades. It is now the third leading cause of cancer death. As with many other cancers, obesity is believed to contribute.
Little progress has been made in the understanding and treatment of pancreatic cancer. Death rates have been rising since record-keeping started, rising to 13 per 100,000 in men and 10 per 100,000 in women today, up from about five per 100,000 in both men and women in the 1930s.
The lack of progress has frustrated many scientists and physicians. The cancer is often fairly advanced when diagnosed, and the five-year survival rate is only 13 percent.
“We need to make progress in specifically understanding what’s driving pancreatic cancers to grow, what treatment will then stave off these cancers, what can prevent it in the first place, and how we can screen for it early,” said Dr. Amy Abernathy, an oncologist who co-founded Highlander Health, which focuses on accelerating clinical research.
Some experts are beginning to acknowledge that environmental exposures may be contributing to early-onset cancer, in addition to the usual suspects: lifestyle, genetics and family history.
“I think that the rise in not just one but a variety of cancers in younger people, particularly in young women, suggests there is something broader going on than variations in individual genetics or population genetics,” said Neil Iyengar, an oncologist at Memorial Sloan Kettering Cancer Center.
“It strongly points to the possibility that environmental exposures and our lifestyles in the U.S. are contributing to the rise of cancers in younger people.”
Public health efforts aimed at reducing risky lifestyle behaviors have focused on people at higher risk and at older Americans, who still bear the brunt of cancer’s burden, he noted.
But the risk factors in young people may be different.
Emerging research hints that maintaining regular sleeping patterns, for example, may also help to prevent cancer, he said.
Lifestyle and behavioral changes can reduce the risk for many cancers, Ms. Siegel said.
“I don’t think people realize how much control they have over their cancer risk,” she said. “There’s so much we can all do. Don’t smoke is the most important.”
Among the others: Maintaining a healthy body weight; not consuming alcohol or consuming in moderation; eating a diet high in fruits and vegetables, and low in red and processed meat; physical activity; and regular cancer screenings.
“There are all these things you can do, but they’re individual choices, so just pick one that you can focus on,” she said. “Small changes can make a difference.”
Science
Scientists find a whale graveyard in the Indian Ocean that’s millions of years old
NEW YORK — Scientists have unearthed communities of marine life — including jellyfish, tubeworms and brittle stars — thriving on a whale graveyard that is millions of years old.
These graveyards form when whale carcasses fall to the sea floor, becoming a sustaining snack for nearby critters. This one, located up to 23,000 feet below the surface of the southeastern Indian Ocean, spans the largest area and is so far the deepest and oldest found.
A whale’s sheer size and the unique chemistry of its bones are the keys to forming these unique underwater neighborhoods, said Xikun Song, a biologist with the Chinese Academy of Sciences’ Institute of Deep-sea Science and Engineering.
“At the same time, the very nature of the deep ocean makes these sites exceptionally difficult for scientists to locate,” Song, who was involved with the latest find, wrote in an email.
Researchers explored the remains during multiple deep-sea submersible trips in 2023, collecting samples and mapping the extent of the necropolis. They found five carcass sites and fossils, including skulls belonging to beaked and baleen whales. The oldest bones date back 5.3 million years.
Feeding and living on the carcasses were myriad creatures, large and small, including sea cucumbers, squat lobsters and saltwater clams. Many of them are likely species that have never been documented, according to findings published Wednesday in the journal Nature.
“The potential number of specimens is just astounding,” said paleontologist Stephen Godfrey with the Calvert Marine Museum in Maryland, who wasn’t involved in the research.
Many factors likely conspired to preserve the bones for millions of years, according to the study authors. They’re dense enough to outlast attacks from bone-eating worms, and located deep enough in the ocean to avoid getting buried by dust and loose particles. The bones also were coated with a light layer of minerals from the surrounding seawater, which may have prevented them from degrading.
Why did so many whales die here? Maybe they were already living in the area and died of natural causes. A few could have perished from exhaustion or illness caused by deep-sea diving. The area’s shape, akin to the letter V, could also have funneled the remains to their resting spot, the authors wrote.
Such discoveries are important because they clue scientists into the vibrant communities that find a way to live even in remote, hard-to-reach environments.
Studying the whale graveyards “is important for understanding how life can adapt to such extreme conditions, not only due to the lack of light and oxygen but also to the incredibly high pressure,” said study co-author and paleontologist Giovanni Bianucci with the University of Pisa in Italy in an email.
Ramakrishnan writes for The Associated Press.
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education and the Robert Wood Johnson Foundation.
Science
El Niño turns crumbling California pier into climate battleground over what to save — and who pays
As a historic El Niño supercharges the Pacific Ocean and San Francisco experiences record high seasonal sea levels, the latest structural casualty of intense wave action is prompting Bay Area politicians to call for help from the state and federal governments.
They want to rebuild a concrete pier shut down this month after officials deemed it unsafe because of cracking from decades of pounding surf and storms.
As waves crashed against the derelict structure Monday morning, U.S. Rep. Sam Liccardo (D-San José) held a news conference and asked the federal government to follow through on $50 million in climate resilience funding promised by the Biden administration but terminated by the Trump administration in 2025.
The city of Pacifica had been on the shortlist for the Building Resilient Infrastructure and Communities program, managed through FEMA. California and 22 other states successfully sued to reinstate the program, but the funding has yet to be allocated.
Liccardo also asked for nearly $1 million in promised funds from the National Oceanic and Atmospheric Administration for a handrail project on the pier and an additional $9 million to protect coastal bluffs.
Coastlines are already being buffeted and inundated by rising seas. With the closed-off Pacifica Municipal Pier in the background, local politicians and community members said they’re on the front lines and want to rebuild.
“Pacifica is ground zero for coastal resilience,” said state Sen. Josh Becker (D-Menlo Park), as he asked Gov. Gavin Newsom to declare a state of emergency and “help us fix this pier and help this community recover again.”
“This is very much a reminder that an ounce of prevention is worth a pound of cure,” he said, noting that previous attempts for funding went unheeded. “We cannot wait until infrastructure fails before we invest in protecting it.”
As climate change starts to become expensive, it prompts questions about what to protect and what to abandon.
Chad Nelson, chief executive of the Surfrider Foundation, a coastal environmental advocacy organization, said city piers provide coastal access to people who can’t swim or walk on the beach; they are often popular fishing spots and tend to serve a broad swath of their communities.
On the flip side, he said, they keep getting beat up by the ocean and costing taxpayers millions of dollars to repair or replace.
In Santa Cruz, a public wharf damaged by storms in 2024 recently reopened after $1.3 million in repairs. In Capitola, a storm-damaged wharf reopened earlier this year after $10 million had been sunk into repairs. The city is now considering building an open-air restaurant, public bathrooms, a bait shop and a boat launch.
“I think the larger question is: Are we subsidizing bad responses to problems that we know are going to persist?” he said, responding to a question about infrastructure that won’t last.
Charles Lester, director of the Ocean and Coastal Policy Center at UC Santa Barbara, agreed with Nelson that it’s important to distinguish public from private benefits.
“There’s a bit of a difference between a public recreational pier, for example, and your private development that’s going to impact the beach,” he said.
And at some point, he said, we have to acknowledge things are only going to get worse.
In a white paper authored by Lester and Nelson, the two described the coming El Niño as a “reckoning” for the California coast.
El Niños result in larger waves, elevated sea levels and powerful storms — “predictable signature(s) of a climate pattern that returns every two to seven years and is expected, as the planet warms, to intensify,” they wrote.
Wave energy along the shore can run 50% above average during an El Niño, while sea levels can climb 6 to 12 inches — flooding coastal homes, roads and infrastructure. Coastal erosion increases by more than 69% during extreme El Niño events, according to the U.S. Geological Survey.
During the 1997-98 El Niño, seven Pacifica seaside houses were condemned after powerful waves and storms made them unsafe and irreparable. Seventeen people in the state died as a result of the historic flooding and storms.
The funding requests for the pier also come as San Francisco sees its highest summer water levels ever. On Saturday, the National Weather Service recorded levels 1.83 feet above normal high tide. Early Monday morning, the popular Pier 14 along the city’s Embarcadero waterfront was submerged.
High surf along the coast killed a young girl in Laguna Beach, and hundreds of people have been rescued at Newport Beach. Water stranded a hiker along the cliffs of San Francisco’s Presidio — requiring a seven-hour rescue mission that ultimately left the hiker and a rescuer injured as the waves crashed them into the rocks.
“This stretch of coast has been a continuous coastal emergency declaration for almost 10 years due to the repeat damage of storms in recent El Niño years,” the mayor of Pacifica, Christine Boles, said.
Pacifica has been planning for climate change for years, she said. But climate change is outstripping those efforts, and without financial and regulatory support from the federal and state governments, the battle will be all but lost.
Science
Californian is infected with rare tick-borne illness. What to know about the deadly bacteria
A Northern Californian has been confirmed as the fourth-ever person diagnosed with a newly recognized and rare tick-borne disease that causes symptoms similar to Rocky Mountain spotted fever.
The California Department of Public Health confirmed the latest case of Rickettsia lanei bacteria in a patient who was diagnosed in April of this year. Two other California cases were reported in 2004 and 2023.
Public health officials told The Times that the infected person “was seriously ill, hospitalized and has since been discharged and is recovering.”
It is unclear how long the person was in the hospital or what their symptoms were. The state agency said it could not disclose the home county of the person but confirmed the infected person lived and worked in Northern California.
Rickettsia lanei comes from the spotted fever group Rickettsia, bacteria transmitted to humans from the bite of an infected tick.
In California three types of ticks — the American dog tick (Dermacentor similis), the Pacific Coast tick (Dermacentor occidentalis) and the brown dog tick (Rhipicephalus sanguineus) — can transmit the bacteria that cause Rocky Mountain spotted fever in humans and dogs, according to the California Department of Public Health.
Symptoms of Rocky Mountain spotted fever can range from fever and a rash to long-term effects that include damage to internal organs or neurological disorders.
The tick-borne disease has been spreading globally since the early 2000s, most notably in Mexico and Brazil, with reported fatality rates that can exceed 50%, according to a study published by UC Davis.
What is Rickettsia lanei?
Rickettsia lanei bacteria were identified this year in a few Pacific Coast ticks, including a tick in Contra Costa County, according to SFGate, where the latest case was first reported in April.
The new bacterium was added to the list of potentially transmittable pathogens in 2024 by the state public health department after its severe symptoms were studied in two cases of infected men nearly 20 years apart, according to a report published in the Centers for Disease Control and Prevention Emerging and Infectious Diseases journal.
“Sustained investment in public health has enabled development of the advanced molecular tools that detected these infections,” the California Department of Public Health said in a statement to The Times.
According to the report, both men fell ill after spending time outdoors, one playing golf at five courses in Alameda and Contra Costa counties within 14 days of the onset of his symptoms. This first patient had fever, headaches, muscle pain, malaise, loss of appetite, diarrhea and abdominal pain, among other symptoms. His condition worsened on his third day in the hospital, according to the report. The man was ultimately in the hospital for 22 days, including 11 in the intensive care unit with a primary diagnosis of rocky mountain spotted fever and a secondary diagnosis of acute kidney injury.
The other infected person had visited and camped at a county park and state beach in San Mateo and Marin counties. The second man reported a five-day history of headaches, vomiting, light sensitivity, neck pain and confusion, according to the report. On the third day of hospitalization, the man became comatose and was intubated, the report stated. After 13 days, he was discharged with a primary diagnosis of severe Rickettsia.
Researchers have known about Rickettsia lanei since 2018 when it was detected in rabbit ticks in Sonoma County, but they didn’t know its potential harm to humans because the rabbit tick rarely bites people.
“The Pacific Coast tick, which bites humans more frequently, may occasionally acquire the organism from an infected rabbit, which is the most likely route for the rare human infections that have been identified,” the state health agency said.
Should I be worried about contracting Rickettsia lanei?
Human infections are rare but could be underreported because Rickettsia lanei symptoms are very similar to those of rocky mountain spotted fever, said Janet Foley, veterinarian and disease ecologist at UC Davis.
“I think it’s so new that I don’t know if anybody’s really gotten a grant to study it or put it under a microscope,” Foley said.
Rickettsia lanei bacteria cases could also have gone undetected for so long because some cases were not severe, she said.
Foley said Californians should be aware of Rickettsia lanei and take precautions against tick bites.
How to keep disease-carrying ticks at bay
The best way to avoid ticks and tick bites is to be vigilant in your surroundings, Foley said, noting that ticks can transmit other diseases such as Lyme disease.
To keep a disease-carrying tick at bay, Foley recommends:
- Covering up your arms and legs when outdoors by wearing pants and long-sleeved shirts.
- Staying out of the grass where a tick can latch onto your clothing. Instead stay on a cleared path.
- Wearing light-colored clothing so it’s easier to spot a tick if one jumps on you.
- After an outdoor activity, take off your clothes, toss them in the wash and take a shower.
- If your dog goes with you for outdoor activities, give it a bath and then apply tick medication.
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