Connect with us

Science

A Test for C.T.E. in the Living May Be Closer Than Ever

Published

on

A Test for C.T.E. in the Living May Be Closer Than Ever

SHICKLEY, Neb. — Chris Eitzmann appeared to excel at the whole lot till he didn’t.

He parlayed a Harvard soccer captaincy into an invitation in 2000 to Patriots coaching camp. After bouncing across the N.F.L., Eitzmann retired from professional soccer in 2002, obtained an M.B.A. from Dartmouth and labored at a number of large monetary corporations in Boston, the place he and his spouse, Mikaela, had 4 kids.

By 2015, nevertheless, Chris started a descent that has develop into acquainted to former soccer gamers troubled with C.T.E., or persistent traumatic encephalopathy, the degenerative mind illness related to repeated blows to the pinnacle.

Chris had beloved mountain biking, operating and lifting weights, however he give up exercising and drank to extra. After a transfer to Mikaela’s household farm again of their residence state of Nebraska two years later, Chris’s conduct turned extra alarming. He would disappear for lengthy stretches of the day and neglect his work. His ingesting obtained worse, and he or she mentioned he would generally drive drunk.

In December 2021, Chris Eitzmann was discovered useless in his Boston condo of alcohol poisoning at 44. Virtually a yr later, medical doctors at Boston College discovered that he had C.T.E., a illness that may nonetheless solely be identified posthumously. Mikaela mentioned that figuring out whether or not her husband had the illness whereas he was alive would have markedly modified the ultimate years of his life.

Advertisement

“If he had identified that it actually was one thing, and never simply this infinite vacuum of not figuring out, if he had an concept that he might have grabbed on to, that readability and understanding would have been so helpful,” she mentioned.

With out remedy choices, a C.T.E. prognosis might present solely readability for former gamers corresponding to Eitzmann who’ve cause to imagine they could be affected. Nevertheless it might ultimately assist present gamers make threat assessments about when to surrender deal with soccer and assist former gamers search remedy.

Researchers are hoping {that a} sequence of latest breakthroughs will assist velocity up the event of a check for C.T.E. within the residing.

At present, the one option to precisely diagnose C.T.E. is to stain mind samples and study them below microscopes to search for the presence of the particular tau proteins related to C.T.E.

But when ongoing research pan out, there could possibly be a check for C.T.E. within the residing in as few as two years, in keeping with one main researcher. The way forward for testing for C.T.E. hinges on growing methods of figuring out the protein with out requiring mind samples. So, scientists in a number of analysis institutes worldwide are working to determine biomarkers for the illness that may be seen in samples of blood, saliva or spinal fluid or by utilizing mind imaging scans.

Moreover, Alzheimer’s diagnostics have superior to the purpose at which blood checks are actually in the marketplace, and firms which have developed these checks are actually trying to create the same blood check for C.T.E.

Advertisement

Essentially the most complete effort to develop a check for C.T.E. within the residing started in 2015, when the U.S. Nationwide Institutes of Well being awarded a $17 million, seven-year grant to the DIAGNOSE C.T.E. Analysis Undertaking.

As a part of the wide-ranging mission, medical doctors from the N.I.H. are monitoring 120 former N.F.L. gamers, 60 former school gamers and 60 folks with no historical past of repetitive head impacts to see in the event that they present signs of C.T.E. Starting in 2016, contributors underwent a three-day examination that included neuropsychological and neurological assessments and have been requested to element their histories of mind trauma, way of life and different well being elements corresponding to genetics in a complete have a look at their well being.

The contributors are actually present process follow-up exams remotely to see in the event that they reveal any C.T.E. signs or if these signs have progressed, and researchers hope that adjustments of their checks — which embody spinal faucets, blood evaluation and neuroimaging scans — will assist them determine biomarkers for C.T.E. The multidisciplinary group of fifty researchers from almost a dozen establishments globally are already publishing among the findings from the three-day exams.

“I now really feel we’re a lot nearer to having fluid biomarkers, and particularly blood-based biomarkers, that can play an necessary position in diagnosing C.T.E. in life,” mentioned Robert Stern of Boston College, the lead investigator for the mission.

The lengthy search to determine C.T.E. biomarkers reached a watershed second in 2019, when a gaggle recognized that the tau proteins particular to C.T.E. have been distinct from these in Alzheimer’s illness and different tau-based neurodegenerative ailments.

Advertisement

Led by Michel Goedert, program chief on the Laboratory of Molecular Biology on the Medical Analysis Council in Cambridge, England, the group printed the findings of their examine, which confirmed that the irregular filaments, or threads inside cells, have been observable, giving hope that their presence could possibly be examined for by way of PET scans.

Positron emission tomography, or PET, scans are checks that use a radioactive compound, or radio tracer, that’s injected into sufferers to create photographs of biochemical processes within the mind and different elements of the physique.

Researchers have been growing radio tracers to be used in research of soccer gamers and others with head trauma to see if these tracers bind to the tau protein related to C.T.E. and irritation within the mind.

“We’re getting very near advancing new radio tracers in people to picture the tau that’s extra prevalent in C.T.E.,” mentioned Neil Vasdev, a radiochemist on the College of Toronto and the director of the CAMH Mind Well being Imaging Centre, who’s growing a number of promising radio tracers that concentrate on figuring out the C.T.E. tau protein. “I prefer to assume that we’re inside two to 5 years, not 10 years” of growing a check for C.T.E. within the residing.

Docs main C.T.E. analysis have for years mentioned {that a} diagnostic check for the residing was 5 to 10 years away. The expectation that the end line is shifting up marks a major change in forecast for analysis that’s difficult by a comparatively small pattern measurement of examine contributors and the necessity for long-range research. However figuring out tracers that may be seen on PET scans might result in diagnosing C.T.E. earlier than its signs are obvious.

Advertisement

“In precept, this could make it attainable to hunt to diagnose these deposits at an early stage,” Goedert mentioned. “You might have to have the ability to determine individuals who have a few of these deposits of their brains earlier than they’ve signs.”

Nonetheless, medical doctors like Gil Rabinovici on the College of California, San Francisco, have hit obstacles to using tracer expertise. Rabinovici’s work examines how one tracer, MK-6240, attaches to C.T.E. tau within the mind of a number of dozen former N.F.L. gamers. The sign from these radio tracers to this point has been weak.

“It’s fairly troublesome since you don’t know if they’ve C.T.E. in life, and in the event you use the scan, you may’t instantly say ‘aha’ and have a stage of reality within the scan,” he mentioned.

The excellent news, Rabinovici mentioned, is that the tau proteins in Alzheimer’s and C.T.E. have extra similarities than variations, so researchers can use among the identical strategies for checks.

“I don’t assume we have to begin from scratch,” he mentioned. “That’s the place I’m cautiously optimistic we’ll discover a tracer that works.”

Advertisement
Continue Reading
Advertisement
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Science

What you need to know about the bird flu outbreak, concerns about raw milk, and more

Published

on

What you need to know about the bird flu outbreak, concerns about raw milk, and more

There is a bird flu outbreak going on. Here is what you need to know about it:

What is bird flu?

Bird flu is what’s known as a highly pathogenic avian influenza virus. The “highly pathogenic” part refers to birds, which the virus is pretty adept at killing. In virology speak, the virus is of the Influenza A type, and is called H5N1. The “H” stands for the protein Hemagglutinin (HA), of which there are 16 subtypes (H1-H16). The “N” is short for Neuraminidase (NA), of which there are 9 subtypes (N1-N9). There are many possible combinations of HA and NA proteins. The two known type A human influenza viruses are H1N1 and H3N2. (Two additional subtypes, H17N10 and H18N11, have been identified in bats).

When did this bird flu first appear?

The current strain of H5N1 circulating the globe originated in 1996, in farmed geese living in China’s Guangdong province. It quickly spread to other poultry and migrating birds. By the early 2000s, it had spread across southern Asia. By 2005, it was observed in the Middle East, Africa and Europe. In 2014, it showed up in North America, but appeared to peter out here while it still raged in Europe, the Middle East and Africa. In 2021, it showed up in wild birds migrating off Canada’s Atlantic coast. Since then, it has spread across North and South America.

What kinds of animals does bird flu effect?

Birds are the primary carriers and victims of the virus. Across the globe, hundreds of millions of wild and domestic birds have died. Since 2021, hundreds of U.S. poultry farms have had to “depopulate” millions of birds after becoming infected, presumably from sick, migrating wild birds. The virus is highly contagious among birds and has a nearly 100% fatality rate. Mammals, too have been infected and died. In most cases, these are scavenging or predatory animals that ate sick birds — and the virus has died in these animals and not become contagious between them. So far, 48 species of mammals have become infected. However, there have been a few cases in which it appears the virus may have spread between mammals, including on European fur farms, on a few South American beaches where elephant seals came to roost, and now among dairy cattle in the United States.

Can humans get bird flu?

Since 2003, when the virus first started spreading through southern Asia, there have been 868 cases of human infection with H5N1 reported, of which 457 were fatal — a 53% case fatality rate. There have been only two cases in the U.S. In 2022, a poultry worker was infected in Colorado and suffered only mild symptoms, including fatigue. In 2024, a dairy worker was infected in Texas and complained only of conjunctivitis, or pink eye.

Advertisement

Why is everyone paying attention to dairy cows?

On March 25, 2024, officials announced that dairy cows in Texas had been infected with bird flu. Since then, the virus has been found in 36 herds across nine states. There are no known cases in California. It is believed that there was a single introduction of the virus from wild bird exposure (either by passive exposure, or maybe from eating contaminated feed), that probably occurred in December in Texas. The virus has since been detected in milk. A study conducted by federal researchers found that 1 in 5 milk samples collected from retail stores had the virus. It is believed that the virus may be passing between cows and that there may be cows that show no symptoms. For the most part, it seems dairy cows only suffer mild illness when infected, and milk production slows. They clear the virus after a few weeks.

Is it safe to drink milk?

Yes — if it is pasteurized milk. Federal officials say the virus they have detected in pasteurized milk samples is inactive and will not cause disease. In the case of raw milk, they urge people to avoid it. That’s because they have found high viral loads in raw milk samples. In addition, studies of barn cats that have consumed raw milk have reported severe consequences. In one cluster of 24 barn cats, half of them died after consuming raw milk, with others suffering blindness, neurological distress and copious nasal discharge. The virus has not been found in sour cream or cottage cheese.

What’s the situation with wastewater?

As health officials and researchers scramble to understand how widespread avian flu is in cattle and the environment, they are analyzing municipal wastewater. One team from Emory University and Stanford University looked at 190 wastewater treatment sites in 41 states. They found a surge of Influenza A virus in the last several weeks at 59 sites. This does not necessarily mean there is bird flu at these sites. However, in places where the team has gone to investigate — including three in Texas where they knew there was H5N1 in dairy cattle — they have found bird flu. Influenza A is generally seasonal in humans — peaking from late fall to early spring. The surge the researchers noticed — including at several sites in California — started after the flu season had died down. Researchers in Texas have also detected H5N1 in the wastewater of nine of 10 cities they tested, all located in Texas. The CDC is also monitoring for Influenza A at roughly 600 sites across the nation.

Advertisement
Continue Reading

Science

Doctors saw younger men seeking vasectomies after Roe vs. Wade was overturned

Published

on

Doctors saw younger men seeking vasectomies after Roe vs. Wade was overturned

Kori Thompson had long wrestled with the idea of having a child.

The 24-year-old worried about the world a kid would face as climate change overtook the globe, fearing the environmental devastation and economic strain that could follow. He had been thinking about getting a vasectomy ever since he learned about the sterilization procedure from a television show.

But “the thing that actually triggered it was the court decision,” Thompson said.

After the Supreme Court overturned Roe vs. Wade nearly two years ago, paving the way for states to usher in new restrictions on abortion, doctors started seeing more young adults seeking vasectomies or getting their tubes tied, emerging research has found.

An analysis by University of Utah researchers, released as an abstract in the Journal of Urology, found that after Dobbs vs. Jackson Women’s Health Organization, a rising share of vasectomy patients were under the age of 30.

Advertisement

That percentage went from 6.2% to 9.8% after the Supreme Court decision, based on their analysis of a national database that includes hundreds of millions of patients.

Among the young patients who pursued the procedure is Thompson, who decided to get a vasectomy in the aftermath of the court ruling. In Georgia where he lives, abortion is illegal roughly six weeks into a pregnancy — a point before some people may learn that they are pregnant.

“If it’s effectively illegal,” Thompson said, “then I felt that this was necessary.” His girlfriend also disliked the effects of hormonal birth control, “so now I’ve decided to go on permanent birth control. It’s way easier.”

The University of Utah researchers found that before the Supreme Court ruling, vasectomy rates were consistently higher in states categorized as “hostile” or “illegal” for abortion by the Center for Reproductive Rights, compared to states that were not as restrictive. The same was true after the ruling.

Yet researchers also found an overall uptick in vasectomy rates after the Dobbs decision — both in states where abortion is heavily restricted and those where it is not.

Advertisement

In California, where state leaders have vowed to protect abortion rights, the rate of men getting vasectomies rose after the court decision, from roughly 7 to 13 per 100,000 potential patients, the Utah team found.

“We’re just seeing an overall increase in vasectomies — regardless of political climate” in each state, said Dr. Jessica Schardein, a urologist at the University of Utah. Schardein said the Supreme Court ruling and increased marketing for vasectomies may have gotten more people thinking about the procedure.

“People in general, even if they don’t have a uterus, are taking responsibility for their reproductive health,” Schardein said.

Her team also examined tubal sterilizations — a medical procedure often called “getting your tubes tied,” performed on the fallopian tubes connected to the uterus — and found that after the court decision, there was an increase in the percentage of patients ages 18 to 30 among those undergoing the procedure.

In Riverside County, Jacob Snow decided to get a vasectomy after the birth of his third child, concluding it was a safer option than his wife had for sterilization. “There’s no reason why all the blame and stress and trying to stop a pregnancy should be placed on the female when I can stop it at my end,” the 28-year-old said.

Advertisement

Even though Snow was already a parent, the doctor balked because of his age, he said. “They said I might change my mind in the future,” Snow recalled. “They flat out just refused.”

Vasectomies are intended to be permanent. The surgery may be able to be reversed with other procedures, but physicians caution that doing so is not a guaranteed option.

Snow ultimately found another doctor to do the procedure. Besides the pushback from the first physician, Snow said some men have been aghast when he tells them he had a vasectomy, saying it would make them feel like less of a man. But Snow said he doesn’t “feel that reproducing is how I need to prove that I’m a man.”

The University of Utah findings, presented at the annual meeting of the American Urological Assn., have been echoed in other recent research.

Last month, researchers from the University of Pittsburgh School of Public Health and Boston University published findings in JAMA Health Forum showing “an abrupt increase” in vasectomies and tube tying following Dobbs, with a sharper increase in tubal ligation.

Advertisement

The difference “likely reflects the fact that young women are overwhelmingly responsible for preventing pregnancy and disproportionately experience the health, social and economic consequences of abortion bans,” University of Pittsburgh assistant professor Jacqueline Ellison said in a statement.

Another analysis in the Journal of Urology that included multiple medical centers around the country — including UCLA — found that after the Dobbs decision, the typical patient seeking a vasectomy was younger than before. Researchers also found that an increased share were childless.

There was also a rise in the number of patients consulting doctors about the medical procedure, said Dr. Kara Watts, a urologist at Montefiore Medical Center in New York City — and longer waits to get the surgery after a consultation. If wait times weren’t an issue, Watts said, “the numbers would probably be even more dramatic.”

Researchers detected a similar trend in the UC San Diego health system, where there was a rise in men seeking consultations about vasectomies after the Dobbs decision, as well as increased rates of patients going through with the procedure after their consultations, according to another review presented at the urology meeting.

Even though California has enshrined abortion rights in its state constitution, “I think that vasectomy consultations and completion rates still increased due to the national media coverage on the Supreme Court ruling,” said Dr. Vi Nguyen, one of the authors of the analysis.

Advertisement

And at Ohio State University, urologists surveyed patients about why they chose to get vasectomies and found that after the Dobbs decision, they were more likely to cite concerns about abortion access or say that “they did not want to bring children into the current political climate.”

Other reasons for wanting a vasectomy, such as health concerns, did not change after Dobbs, the survey found. Dr. Jessica Yih, an assistant professor of urology at the Ohio State University, wasn’t surprised.

“Immediately after the Dobbs ruling, many people were extremely concerned about their reproductive rights,” Yih said in an email. “We had a threefold increase in referrals of patients who were wanting to be scheduled to discuss vasectomies and the number of vasectomies performed around this time increased dramatically.”

Abortion has been a sharply contested issue in Ohio, where a law banning abortion after six weeks of pregnancy initially went into effect after the Dobbs ruling. That ban was later put on hold in court, and Ohio voters have since backed protections for abortion access in its state constitution.

“Many patients told us at our clinics that they wanted their vasectomies done as soon as possible due to concerns about restrictions in abortion access,” Yih said.

Advertisement
Continue Reading

Science

Want to live to 100? That may depend on your sex

Published

on

Want to live to 100? That may depend on your sex

Do you want to live to 100? The path to becoming a healthy centenarian — as opposed to just a centenarian — is surprisingly different for those born as women and men, says social researcher and author Maddy Dychtwald. And it’s never too early to start on the journey, even when you’re young and spry. (We’re talking to you, zoomers.)

As co-founder of Age Wave, a nonprofit think tank focusing on longevity and aging, Dychtwald has been researching these topics for nearly 40 years. In her new book, “Ageless Aging: A Woman’s Guide to Increasing Healthspan, Brainspan, and Lifespan,” Dychtwald addresses the most recent aging picture for women and identifies a holistic plan for longevity. It weaves together science and medicine, psychology and spirituality, as well as financial advice in a research-based guidebook that’s brimming with actionable steps.

“There’s this ripple effect,” Dychtwald says of the lifestyle she recommends for maximizing healthspan — meaning how long you are living in good health, versus how long you are just living. “If you can impact one piece — sleep, nutrition, fitness, having a sense of purpose and connection — it begins to affect the others.” This interview has been edited for length and clarity.

Shelf Help Logo

Shelf Help is a new wellness column where we interview researchers, thinkers and writers about their latest books — all with the aim of learning how to live a more complete life.

Advertisement

How is longevity different for women than men?

Woman have actually won the longevity lottery. We live, on average in the United States, six years longer than men. So that’s incredibly positive. But there is a dark side to this. And that is: We women, on average, spend the last 12 to 14 years in declining health. So we are not doing a great job of matching our healthspan to our lifespan. There’s a gendered gap when it comes to healthspan. Why? I don’t know that the answer is clear, even in the minds of scientists. What we do know is that estrogen has protective properties for women. But once their estrogen levels decline, they have more health challenges than men do, as they get older. But it’s something scientists don’t fully understand yet.

If women are 51% of the population, doesn’t it stand to reason that scientists would better understand this by now?

You would think! I think the healthcare system, overall, is well-meaning. But it’s been created by men and as a result, the focus has really been more on men than women. One great example of how women can, as a community, really motivate physicians and researchers and scientists to change is the whole breast cancer issue. Women really spoke out on this and I think, as a result, we’ve seen great strides in research and survival rates and treatment methodologies.

Advertisement
A headshot of a smiling woman with brown hair, wearing a red shirt

Author Maddy Dychtwald.

(Lisa Keating Photography)

You endured a health challenge, which is one of the things that led to your writing this book. Can you tell us about that?

I’m a big exerciser, it’s how I manage stress. I started getting pain in my hips, to the point where I was limping. I did PT, I got cortisone treatments, I did a variety of things to manage the pain. But it wasn’t solving the problem. Turns out I needed double hip surgery — I was 68, which is young for the condition I had. But they couldn’t see me for months — and I was in excruciating pain. I started researching and learned, from experts in my network, that I needed to get my inflammation levels down. I went on an anti-inflammation diet — I cut out gluten, sugar and dairy — and I found that within six weeks all my pain went away. I thought: “Whoa, there are all these things that we can all do — and they don’t necessarily cost any money — to live better, longer.” I started looking at other things I could do. I worked with a psychiatrist at Harvard who taught me about meditation and affirmations. I was doing precovery, essentially — preparing for my surgery in advance. And it made a difference. This book is the distillation of all that, along with the work I’ve been doing at Age Wave for 40 years.

New research around genetics versus lifestyle choices also informs the book — and your decision to direct it at women. What does the latest research tell us about how to influence our destiny?

Advertisement

We used to just assume that genetics were our destiny. That whatever our genetic package is, that’s kind of the hand that we were dealt. But, in fact, according to the most recent science from Alphabet’s Calico Life Sciences and other research, up to 90% of our health and longevity are literally within our control. And I find that an incredibly empowering piece of information. It gives us almost total agency. I didn’t want to just keep that information to myself, I wanted to share it with the world. There are a lot of books out there on longevity, but there aren’t many that really focus in on women and longevity. And obviously, women and men are really different.

We used to just assume that genetics were our destiny. That whatever our genetic package is, that’s kind of the hand that we were dealt. But, in fact, according to the most recent science … up to 90% of our health and longevity are literally within our control.

— Maddy Dychtwald

During COVID, I was home more than I had been before. There were so many health issues I saw around me and I had an opportunity to really lean into my own sense of purpose. And in order to lean into it in a way that felt good to me, I wanted to [educate] women in their 40s, 50s, 60s and beyond. There are tens of millions of women just in the U.S. in that age group who are starting to feel the aches and pains of getting older, or who are coping with a chronic degenerative disease, or just dealing with the reality of menopause — and who are looking for solutions. I wanted to give women a one-stop resource to clear up the confusion, give them straightforward answers based on science as well as action steps to live better, longer.

Advertisement

You talk about a “holistic recipe” for healthy aging as a woman. What are the ingredients to that — what daily activities, for example, do you incorporate to promote longevity?

There are a lot of books out there on sleep or exercise or nutrition or hormones or having a positive attitude — and by the way, our attitudes toward our own aging can actually add 7½ years to our lifespan — but it’s not just about one thing, it’s all these things working together. They don’t exist in silos.

The cover of Maddy Dychtwald's book "Ageless Aging"

Take finances — there’s a gender pay gap. I encourage all women to take charge of their finances. If you don’t have your financial house in order, chances are it will affect your stress levels, your health, your well-being. And you may not even have the financial well-being to pay for your health — and that’s a scary place to be.

If you exercise effectively, it affects your mood and your stress. That helps with sleep, which helps with cognition and so many other things, including managing your finances. It’s cyclical.

Sleep is such a key ingredient. What do you do to manage that?

Advertisement

Sleep is not my superpower. But I learned there were things I could do. One was to really be mindful of my circadian rhythms; controlling our sleep-wake cycles are very important. I learned that what I did during the day was as important, if not more important, than what I did at night to go to sleep. It’s simple — anyone can do it — and it doesn’t cost a penny. Which is: When you get up first thing in the morning, watch the sun rise for 10 minutes. If it’s already up, get sun on your skin for 10 minutes. I do what I call “stacking my habits.” So at the same time, I do some breathing exercises that help me be calm and energetic simultaneously — what a great way to start my day.

One surprising piece of new research that you cite is that exercise has a bigger impact on health, and staving off brain decline later in life, for woman over men.

Yes. We already know that exercising in the morning is the best time of day to exercise, it brings optimal results, and it’s best on an empty stomach. But brand-new research, in a February 2024 study from the Smidt Heart Institute at Cedars-Sinai, says that women don’t have to exercise as hard, or as long, as men to get optimal results. They can get the same health benefits as men from exercise in less time.

For example, women can reduce their risk of death by 18% by doing 140 minutes of moderate aerobic exercise per week, while men need 300 minutes to achieve the same benefit. Women can also achieve the same survival benefit from moderate to vigorous aerobic exercise, like cycling or brisk walking, after 2½ hours per week, while men need about five hours. And when it comes to building muscle mass, strengthening exercises such as weightlifting or core exercises, women can achieve the same positive benefits after one session weekly while men need three sessions.

TAKEAWAYS

Advertisement

From “Ageless Aging”

You talk about two topics that demand the medical community’s much closer attention. What are they?

Brain health — no one wants to talk about anything above the neck — and hormones. Hormones affect our cognition, sleep, joints and bones, mood. If you’re not able to sleep at night, it affects your brain health, brainspan and longevity. If your bone density is impacted, you’re more likely to fall, and that could lead to health issues.

Advertisement

And Alzheimer’s disease is twice as likely to happen to women than men — people don’t want to talk about it. It’s super scary. But there are things we can do. Dr. Andrea Pfeifer, a neurosurgeon and CEO of AC Immune, a company working on a vaccine for Alzheimer’s, says probiotics are what she takes — the gut-brain connection is very real. Many physicians recommend the Mediterranean diet. I do the anti-inflammatory diet.

Another thing is limiting or stopping alcohol. And exercise — every single brain expert I spoke to said that’s the No. 1 thing to protect healthspan and brainspan. The fear of cognitive decline and Alzheimer’s for women is real, but only 4% of women have a genetic connection. And we can take steps to prevent or delay it.

Are there any positive sides of aging for women?

We gain a certain amount of wisdom and experience as we get older. According to recent studies we’ve done at Age Wave, women, as it turns out, from the age of 50 on, they seem to be gaining more confidence in themselves and their lives, whereas men seem to plateau out at around 50. This is all in general, of course. But for women, empowering.

Maggie Chiang / For The Times

Shelf Help is a new wellness column where we interview researchers, thinkers and writers about their latest books — all with the aim of learning how to live a more complete life. Want to pitch us? Email alyssa.bereznak@latimes.com.

Advertisement
Continue Reading

Trending