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Study finds slightly higher risk of autism diagnosis in areas with more lithium in drinking water, but experts say more research is needed | CNN

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Study finds slightly higher risk of autism diagnosis in areas with more lithium in drinking water, but experts say more research is needed | CNN



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A brand new examine discovered a reasonably larger threat of autism spectrum dysfunction in youngsters born to pregnant folks uncovered to faucet water with larger ranges of lithium, however consultants warning that this affiliation doesn’t present a direct hyperlink between the 2.

About 1 in 36 youngsters within the US is identified with autism spectrum dysfunction (ASD) every year, in accordance with knowledge from the US Facilities for Illness Management and Prevention.

Scientists nonetheless don’t know the precise reason behind autism, a developmental dysfunction. Genetics could also be an element, however some have been potential environmental causes, too.

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Circumstances could also be on the rise, however that can be unclear. One examine revealed this 12 months on circumstances within the New York-New Jersey space discovered that autism analysis charges tripled amongst sure age teams between 2000 and 2016. A 2021 report discovered related will increase in circumstances, however the CDC says the elevated variety of circumstances is probably linked to extra docs screening for the situation.

Lithium is an alkali metallic that may be discovered naturally in some meals and floor water. It’s utilized in batteries, grease and air conditioners, in addition to within the therapy of bipolar dysfunction and a few blood problems. Its ranges in US ingesting water aren’t regulated, in accordance with the US Geological Survey.

A brand new examine, revealed Monday within the journal JAMA Pediatrics, discovered a small affiliation between lithium and autism analysis in Denmark, the place the researchers say the extent of lithium in ingesting water is just like that in American water techniques.

The researchers checked a database of individuals with psychiatric problems for kids born between 2000 and 2013 to search out data on 8,842 circumstances of ASD and 43,864 members who didn’t have ASD. They then measured the focus of lithium in 151 public waterworks that served greater than half of the Danish inhabitants and mapped out the place pregnant folks lived in relation.

As lithium ranges in water elevated, there was a modest elevated threat of an ASD analysis. Particularly, in contrast with folks on the lowest publicity degree, those that had the second and third highest publicity throughout being pregnant had a 24% to 26% larger threat of ASD identified in youngsters. The group with the best publicity had a 46% larger threat than these on the lowest degree of publicity.

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The researchers couldn’t inform how a lot water the pregnant folks drank, however they picked Denmark partly as a result of residents there eat a few of the lowest quantities of bottled water in Europe.

Consultants say it’s necessary to notice that the analysis can’t present that lithium publicity leads on to an autism analysis.

Additional examine is required, mentioned examine co-author Dr. Beate Ritz, a professor of neurology within the David Geffen Faculty of Drugs at UCLA, and a professor of epidemiology and environmental well being on the UCLA Fielding Faculty of Public Well being.

“Any ingesting water contaminants which will have an effect on the growing human mind deserve intense scrutiny,” Ritz mentioned in a information launch. She added that the analysis would must be replicated in different nations to look for the same connection.

The implications of the findings are advanced so far as public well being coverage is anxious, in accordance with an editorial revealed alongside the examine. Lithium ranges in water, at concentrations that the examine related to a possible ASD threat, have additionally been linked with well being advantages resembling decrease charges of hospitalization for psychiatric problems and suicide.

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“If all these of associations are legitimate, the knowledge of Solomon will probably be required to develop pointers for lithium in ingesting water which might be maximally protecting of all the inhabitants,” wrote Dr. David C. Bellinger, a professor of neurology and psychology at Harvard Medical Faculty. “Till the fundamental biology of ASD is healthier understood, will probably be troublesome to differentiate causal from spurious associations.”

Dr. Max Wiznitzer, director of the Rainbow Autism Middle at College Hospitals Rainbow Infants and Kids’s Hospital in Cleveland, factors to different analysis on the results of lithium on pregnant individuals who take it for psychological well being problems. These research – which take a look at folks uncovered to a lot larger ranges than are present in ingesting water – don’t present a reference to autism spectrum dysfunction.

“It’s an fascinating affiliation, however causation is unquestionably not confirmed,” mentioned Wiznitzer, who was not concerned within the new analysis. “We have now to see if there’s a viable and biologically believable mechanism by which a small quantity of lithium within the water provide can one way or the other do that, but pharmacologic dosing of lithium in girls with bipolar dysfunction has not been reported to be inflicting elevated threat of ASD.”

Different research have additionally advised connections between ASD and environmental exposures to issues like pesticides, air air pollution and phthalates. However none of them factors to any of those elements as a direct reason behind the dysfunction.

A hyperlink between environmental publicity and ASD is difficult to show, Wiznitzer mentioned. With analysis displaying that elevated publicity to air air pollution raises the chance of giving delivery to a baby with ASD, for instance, he typically wonders whether or not air pollution is the figuring out issue or if it’s simply the populations who dwell in additional polluted areas.

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“There’s loads of hypothesis about about environmental elements, however what number of of them are actually causally related?” Wiznitzer mentioned. “We’re bombarded with quite a lot of environmental stressors in our on a regular basis lives. We have now to determine how one can principally safely navigate them, and that is most likely not one which’s excessive on our listing.”

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Video: Heavy Rains and Wind Wreak Havoc on the West Coast

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Heavy Rains and Wind Wreak Havoc on the West Coast

A series of atmospheric rivers has caused flooding and damage in the Pacific Northwest and Northern California, knocking out power for hundreds of thousands of people.

It just crashed through the front of the house, crashed through the kitchen, and it broke the whole ridge beam. The whole peak of the house is just crushed.

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How long will Trump’s honeymoon with the stock market last?

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How long will Trump’s honeymoon with the stock market last?

Few were surprised when US stocks jumped after Donald Trump’s decisive victory in the presidential election. Amid widespread assumptions of weeks of uncertainty, a clear result was always likely to prompt an initial relief rally. More unexpected was what has happened since.

The president-elect has nominated a string of hardliners to senior positions, signalling his intent to push ahead with a radical agenda to enact sweeping tariffs and deport millions of illegal immigrants that many economists warn would cause inflation and deficits to spiral upward.

Yet the stock market — the economic barometer most closely watched by the general public, and one often referenced by Trump himself — seems to have shown little sign of concern.

The S&P 500, Wall Street’s benchmark index for large stocks, is still up about 3 per cent since the vote, even after a slight pullback. The main index of small cap stocks is up almost 5 per cent.

The relative cost of borrowing for large companies has also plummeted to multi-decade lows, and speculative assets such as bitcoin have surged.

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Under the surface, not every part of the stock market has been so calm. A Citi-created index of stocks that may be vulnerable to government spending cuts, for example, has tumbled 8 per cent since the election, while healthcare stocks have been hit by the nomination of vaccine sceptic Robert Kennedy Jr to head the health department.

The prospect of inflation arising from tariffs and a tighter labour market has also spooked many in the $27tn Treasury market, with some high-profile groups warning about over-exuberance.

But the contrasting signals raise some key questions for traders and policymakers alike: are equity investors setting themselves up for a fall by ignoring high valuations and potential downsides of Trumponomics, or will they be proved right as gloomy economists once again have to walk back their dire prognoses?

“Any time . . . you get to the point where markets are beyond priced to perfection, you have to be concerned about complacency”, says Sonal Desai, chief investment officer at Franklin Templeton Fixed Income.

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But, she adds, “the reality is you also need to very actively look for triggers for sell-offs, and right now . . . I think the underlying economy is strong and the policies of the incoming administration are unlikely to move that significantly.”


The bull case was on full display at the Wynn resort in Las Vegas this week, where more than 800 investors, bankers and executives were gathered for Goldman Sachs’ annual conference for “innovative private companies”.

With interest rates now trending downward, capital markets specialists had already been preparing for a recovery in stock market listings and mergers and acquisitions activity, but the election result has poured fuel on the fire.

Walter Lundon, a trader, shows off his pro-Trump T-shirt on the floor of the New York Stock Exchange
Walter Lundon, a trader, shows off his pro-Trump T-shirt on the floor of the New York Stock Exchange. Investors believe Trump will follow through on pledges to cut taxes and regulation © Timothy A. Clary/AFP via Getty Images

With Republicans controlling both houses of Congress in addition to the White House, investors are assuming that it will be easy for the Trump administration to fulfil promises to slash corporate taxes and scale back regulation. At the same time, more contentious proposals such as the introduction of tariffs were frequently dismissed by attendees as a “negotiating tactic”.

David Solomon, Goldman chief executive, said at the conference: “The market is basically saying they think the new administration will bring [regulation] back to a place where it’s more sensible.”

One hedge fund manager in attendance sums up the atmosphere more bluntly. “There are lots of giddy investors here getting excited about takeout targets,” he says. “M&A is now a real possibility because of the new administration. That’s been the most exciting [element of Trump’s proposals] . . . I think the mood is better than it’s been in the past four years.”

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The emphasis on tax and deregulation is clear when looking at which sectors have been the biggest winners in the recent market rally: financial services and energy.

The S&P 500 financials sub-index has jumped almost 8 per cent since the vote, while the energy sub-index is up almost 7 per cent. Energy executives have celebrated the president-elect’s pledges to withdraw from the Paris climate agreement and open up federal lands for fracking in pursuit of US “energy dominance”.

The Russell 2000 index, which measures small cap companies, has also risen faster than the S&P thanks to its heavy weighting towards financial stocks, and a belief that smaller domestically focused companies have more to gain from corporate tax cuts.

Chris Shipley, co-chief investment officer at Fort Washington Investment Advisors, which manages about $86bn, says that “we believe the market has acted rationally since the election”, citing the concentration of gains in areas that could benefit from trends such as deregulation and M&A.

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Even policies that most mainstream economists think would have a negative effect overall — like a sharp increase in tariffs — could ironically boost the relative appeal of US stocks by hitting other countries even harder.

The Europe-wide Stoxx 600 index, for example, has slipped since the election as investors bet the export-dependent region will be heavily hit by any increase in trade tensions. At the same time, the euro has dipped to a two-year low against the dollar.

“The ‘America First’ policy, not surprisingly, will be good for the US versus the rest of the world,” says Kay Herr, US chief investment officer for JPMorgan Asset Management’s global fixed income, currency and commodities team.


The worry among economists and many bond investors, however, is that Trump’s policies could create broader economic problems that would eventually be hard for the stock market to ignore.

Some of Trump’s policies, such as corporate tax cuts, could boost domestic growth. But with the economy already in a surprisingly robust state despite years of worries about a potential recession, some like former IMF chief economist Olivier Blanchard fear an “overheating” that would lead to a resurgence in inflation and a subsequent slowdown.

A shale gas well drilling site in Pennsylvania
A shale gas well drilling site in Pennsylvania. The incoming Trump administration is expected to open up federal lands for fracking in pursuit of US ‘energy dominance’ © Keith Srakocic/AP

Demand-driven inflation could be exacerbated by supply-side pressures if Trump follows through with some of his more sweeping policy pledges.

On the campaign trail, Trump proposed a baseline 10 per cent import tariff on all goods made outside the US, and 60 per cent if they are made in China. Economists generally agree that the cost of tariffs falls substantially on the shoulders of consumers in the country enacting them. Walmart, the largest retailer in the US, warned this week it might have to raise prices if tariffs are introduced.

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Deporting millions of undocumented immigrants, meanwhile, would remove a huge source of labour from the US workforce, driving up wages and reducing the capacity of US companies to supply goods and services.

Economists at Morgan Stanley and Deutsche Bank both predicted this week that Trump’s policies would drag on GDP growth by 2026, and make it harder for the Federal Reserve to bring inflation back to its 2 per cent target.

Tom Barkin, president of the Richmond Fed and a voting member on the rate-setting Federal Open Market Committee, says he understands concerns among the business community about tariffs reigniting inflation, and says the US was “somewhat more vulnerable to cost shocks” than in the past.

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But some investors believe the risks to be minimal. “In our view, the inflationary concerns . . . regarding tariffs are overblown,” says Shipley of Fort Washington.

Fed policymakers have been quick to stress that they will not prejudge any potential policies before they have been officially announced, but bond investors have already scaled back their forecasts for how much the central bank will be able to cut interest rates over the next year.

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Interest rate futures are now pricing in a fall in Fed rates to roughly 4 per cent by the end of 2025, from the current level of 4.5-4.75 per cent. In September, investors were betting they would fall below 3 per cent by then.

Meanwhile, the yield on the 10-year Treasury note, which rises when prices fall, is up about 0.8 percentage points since mid-September to 4.4 per cent. As a consequence, the average rate on a 30-year mortgage is also ticking upward, to near 7 per cent.

“The bond market has been very focused on deficits and fiscal expansion, and the equity market has been focused, it seems, on deregulation and the growth aspect,” says JPMorgan’s Herr. But “at some point, a higher [Treasury yield] is problematic to equities”.

In part, that is because higher bond yields represent an alternative source of attractive returns at much lower risk than stocks. But the more important impact could come from the warning signal a further increase in yields would represent.

The rise in yields is being driven by concerns both about inflation and also higher government debt levels, says Kristina Hooper, chief global market strategist at Invesco. “2024 marks the first year in which the US spends more to service its debt than it spends on its entire defence budget. And that’s not sustainable in my opinion over the longer term, and so we have to worry about the potential for a mini Liz Truss moment.”

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Former UK prime minister Truss’s attempt to introduce billions of pounds of unfunded tax cuts and increased borrowing in 2022 caused a massive sell-off in British government debt that spilled into currency and equity markets.

Demonstrators in New York protests against Trump’s immigration proposals
Demonstrators in New York protest against Trump’s immigration proposals. His plans to deport millions of undocumented immigrants would remove a large chunk from the US workforce © Michael Nigro/Sipa USA via Reuters Connect

The structure and scale of the US Treasury market makes this sort of “bond vigilantism” less likely, strategists and investors stress, but many institutions have begun paying more attention to the possibility.

“Over the next two to four years, do I think that there’s a very serious risk of bond vigilantes coming back? Absolutely. And that’s entirely based on what the multiyear plan will be, and the impact which comes out of it,” says Franklin Templeton’s Desai.


Trump and his advisers have dismissed concerns about their economic agenda, arguing that policies such as encouraging the domestic energy sector will help keep inflation low and growth high.

Even if they do not, several investors in Las Vegas this week suggested that the president-elect’s personal preoccupation with the stock market would help restrain him from the most potentially damaging policies.

“I think Trump and all his donors measure their success and happiness around where the US stock market is,” says the hedge fund manager. “It’s one reason why I’m pretty bullish despite the market being where it is.”

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Economists have also consistently underestimated the resilience of the US economy in recent years. The combination of Trump’s attentiveness and economists’ poor past forecasting means even sceptical investors are wary of betting against the US market.

“There are risks out there,” says Colin Graham, head of multi-asset strategies at Robeco. “If some of the more extreme policies that were talked about during the campaign get implemented, our core view for next year is going to be wrong.

“But what is our biggest risk here? Missing out on the upside. The momentum is very strong.”

Data visualisation by Keith Fray and Chris Giles

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Can Matt Gaetz return to Congress? He says he won’t.

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Can Matt Gaetz return to Congress? He says he won’t.

Gaetz not returning to Congress

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Gaetz on not returning to Congress after dropping out of Trump attorney general consideration

02:05

Former Rep. Matt Gaetz of Florida says he doesn’t intend to return to Congress in January, after resigning from his seat and withdrawing from consideration as U.S. attorney general. 

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Gaetz announced his withdrawal Thursday, citing the distraction his impending nomination was causing, and President-elect Donald Trump soon afterward said former Florida attorney general Pam Bondi would be his new pick for the job. But Gaetz won reelection to his U.S. House seat earlier this month, so there were some questions about whether he was considering a return to Congress in January. 

But Gaetz told conservative personality Charlie Kirk on Friday that he doesn’t intend to go back to Congress, though he vowed to continue to fight for Trump and do “whatever he asks of me.”

“I’m still going to be in the fight, but it’s going to be from a new perch,” Gaetz told Kirk. “I do not intend to join the 119th Congress. … Charlie, I’ve been in an elected office for 14 years. I first got elected to the state house when I was 26 years old, and I’m 42 now, and I’ve got some other goals in life that I’m eager to pursue with my wife and my family, and so I’m going to be fighting for President Trump. I’m going to be doing whatever he asks of me, as I always have. But I think that eight years is probably enough time in the United States Congress.”

But it may not be the end of his political career. Florida Gov. Ron DeSantis, first elected in 2018, will not be running again in 2026, since he’s limited by law to two terms as the state’s chief executive. 

Gaetz stepped down from Congress as the House Ethics Committee was weighing whether to release the report from its yearslong investigation into sexual misconduct and illegal drug use allegations. The committee lacked sufficient votes to release the report earlier this week but will, according to Democratic Rep. Susan Wild of Pennsylvania, reconvene on Dec. 5 to “further consider” the matter. 

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