Health
‘Sleep disorder drove my son to suicide,’ New York mother says: ‘Broke my heart’
This story discusses suicide. If you or someone you know is having thoughts of suicide, please contact the Suicide & Crisis Lifeline at 988 or 1-800-273-TALK (8255).
Chronic lack of sleep can cause a long list of physical and mental issues — and for one young man, his mother believes it led to his death.
Derek McFadden was just 23 when he took his own life on Aug. 17, 2018, in Tucson, Arizona.
His mother, Robin McFadden, who lives in Tuxedo Park, New York, said she believes her son’s insomnia was the “only driver” of his suicide.
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Derek McFadden was an “extremely funny kid” who loved swimming, snow-skiing and cuddling, his mother said — but for most of his life, he struggled with debilitating insomnia.
At around 8 years old, he started taking small doses of sleeping medication, which helped for several years.
Derek McFadden, pictured at left with his mom Robin McFadden, was 23 when he took his own life on Aug, 17, 2018, in Tucson, Arizona. (Robin McFadden)
Around the time he turned 18, during his senior year of high school, the medication stopped working, McFadden said.
“He never got a good night’s sleep, but he soldiered through his school day and then would come home and lie down on his bed, exhausted, but couldn’t fall asleep,” she told Fox News Digital in an interview.
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McFadden took her son to multiple doctors and they tried different medications — none of which worked, she said.
“Derek would just lie there at night, and he was so tired, but he couldn’t fall sleep,” she said.
Amid the sleep struggles, her son managed to graduate from high school — but things got even worse when he left for college at the University of Arizona.
Derek McFadden, left, is pictured with his older brother Jake McFadden. (Robin McFadden)
He’d chosen Arizona because he was an “avid outdoorsman” who loved fly-fishing, going off-roading in his Jeep and spending time with his dog, which he’d adopted for emotional support.
“Our hope was that with Derek being in Arizona, the sunshine during the day would stimulate his brain to wake up so he could go to sleep at night, but it just didn’t work,” McFadden said.
The doctor’s visits continued, but none of the experts could figure out what was causing the insomnia.
“There was something wrong in his brain that was preventing him from sleeping.”
“Every doctor would assume it was sleep hygiene, and that he was doing something wrong,” McFadden said.
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“They assumed that because he was 18, 19 or 20 years old that he was playing video games all night.”
She added, “But Derek knew sleep hygiene. He had done so much research on his own. There was something wrong in his brain that was preventing him from sleeping.”
Derek McFadden, far left, is pictured with his brother, mother and father. (Robin McFadden)
The family looked into holistic approaches, including hypnosis, acupuncture and “brain training,” but “nothing seemed to work,” McFadden said.
Many nights, he would go the entire night without sleeping — sometimes up to three days in a row, she said.
“It was really, really bad,” McFadden said.
Physical and mental toll
As the months went by and sleep continued to elude her son, McFadden said it began to take a toll on his immune system.
After consecutive nights without sleeping, he developed bruises all around his eyes.
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“Derek was constantly getting sick, and that made him feel like he was not a normal kid,” she said. “He just couldn’t fight anything off. He was always at Urgent Care.”
Her son developed severe acid reflux and stomach pain, to the point where it became difficult for him to eat.
“Sometimes his insomnia got so severe that he couldn’t keep any food or fluids down at all,” McFadden said.
Multiple times, he ended up in the emergency room with dehydration and severe cramping, she said.
Derek was an “avid outdoorsman” who loved fly-fishing, going off-roading in his Jeep and spending time with his dog, which he’d adopted for emotional support, his mother said. (Robin McFadden)
The lack of sleep also changed her son’s demeanor and personality, McFadden said.
“Derek had tremendous mood swings — he became anxiety-ridden and depressed,” she recalled.
“He would have hallucinations, and was constantly losing things. He couldn’t think clearly.”
On the rare occasion that her son had a good night’s sleep, McFadden said, he was “a completely different person, as happy as could be.”
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“It broke my heart, because he was such a happy, funny, huge-hearted person, and it was really sad to watch his decline.”
Unable to keep up with his studies, her son had to drop out of college.
“He couldn’t even hold a job because he couldn’t sleep at night,” McFadden said.
“He saw there was no cure, no future, and he just didn’t see a point in going on.”
In July 2018, when her son came home from Tucson for the summer, McFadden knew something had shifted.
“We were sitting on the sofa and he said to me, ‘Mom, I’m gonna die young,’” she recalled.
“And I said, ‘Derek, why do you say that?’ And he said, ‘Because my mind and body can’t take the sleep deprivation.’”
Derek McFadden, left, is pictured with his older brother. After the tragedy, his mother said she realized her son had likely been planning his suicide in recent weeks. (Robin McFadden)
Her son had also expressed that he didn’t want to have children because he didn’t want to pass on the disorder, McFadden said.
“He saw there was no cure, no future, and he just didn’t see a point in going on,” she said. “Physically, he was starting to fall apart, and mentally, his cognitive ability was going.”
“Physically, he was starting to fall apart.”
Four weeks later, McFadden got an early-morning call from the Tucson Police Department notifying her that her son had taken his life.
After the tragedy, McFadden realized that her son had likely been planning his suicide in recent weeks.
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“He had contacted some old friends, and in his text messages and phone calls, he sounded very serene, relieved and calm,” she recalled. “I truly believe Derek had made the decision. He just saw no future for himself.”
The sleep-suicide link
Studies have suggested a likely connection between sleep and suicide.
Research published in the journal Current Psychiatry Reports found that treating insomnia and nightmares, or addressing the source of those issues, could help prevent “the rising threat of suicide.”
“Sleep is crucial for emotional and psychological balance.”
Dr. Brett Osborn, a Florida neurologist and longevity expert with the firm Senolytix, said there is a “significant body of research” suggesting a link between sleep deprivation and an increased risk of suicide.
“Sleep is crucial for emotional and psychological balance,” he told Fox News Digital in an interview.
“Lack of sleep can lead to mood disturbances, irritability and decreased stress tolerance, all of which can worsen feelings of despair or depression — potentially leading to suicidal thoughts.”
On the rare occasion that her son had a good night’s sleep, McFadden said, he was “a completely different person, as happy as could be.” Derek McFadden is pictured here with his mother, Robin McFadden. (Robin McFadden)
Sleep deprivation can also affect cognitive functions, the doctor continued.
“This impairment can make it harder for individuals to see alternative solutions to problems or seek help, potentially increasing the risk of suicidal behavior,” he said.
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Sleep problems are also commonly associated with psychiatric disorders, such as depression and anxiety, which are themselves significant risk factors for suicide, according to Osborn.
“Sleep pathology is extremely complex and challenging, because sleep itself is poorly understood.”
“Insomnia and disrupted sleep patterns are particularly prevalent in these conditions,” he warned. “This can be a source of diagnostic confusion and resultant treatment errors.”
Sleep also affects various biological processes, Osborn noted — “including the regulation of neurotransmitters like serotonin (which is involved in mood regulation) and stress hormones like cortisol.”
Derek McFadden was an “extremely funny kid” who loved swimming, snow-skiing and cuddling, his mother said. (Robin McFadden)
“Chronic sleep deprivation may lead to dysregulation in these systems, which could contribute to depressive symptoms and suicidal ideation.”
While the majority of insomnia patients respond to lifestyle changes and/or medications, Osborn noted, there is a subset of patients who are “more difficult to manage.”
“Often, there are underlying medical problems, like reflux, that fly under the radar and predispose the individual to insomnia,” he told Fox News Digital.
Derek McFadden, center, in cap and gown, is pictured with his family at his high-school graduation. (Robin McFadden)
“Another issue is the potentially reciprocal relationship between depression and anxiety,” Osborn said.
“Sleep pathology is extremely complex and challenging, because sleep itself is poorly understood,” he continued. “A multimodal, interdisciplinary approach — involving a psychiatrist and a sleep specialist — is always best.”
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Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, agreed that there is a proven link between insomnia, stress, anxiety and depression.
“Since suicide is a manifestation of severe depression, I think there is a link there, too, though insomnia wouldn’t be the entire cause,” he told Fox News Digital.
Fly-fishing was one of Derek McFadden’s favorite hobbies. (Robin McFadden)
Siegel refers to it as a “cycle of worry.”
“Anxiety interferes with sleep, which then makes you more anxious and more sleepless, especially if you add caffeine to combat the grogginess,” he said.
During sleep, the brain relaxes and “cleanses” itself, Siegel said.
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“Waking up refreshed can improve mood, especially when accompanied by exercise,” he noted.
For those with severe insomnia, Siegel recommends undergoing a full sleep study/evaluation — typically with an EEG or video monitoring — to help determine the causes.
“Severe, resistant cases require evaluations by sleep specialists, neurologists and psychiatrists,” he added.
Call for awareness
The most “disheartening” part of her son’s tragedy, according to McFadden, was a lack of support from the health community, in her view.
“Other than sleep apnea and bad sleep hygiene, the medical community does not seem to believe that severe insomnia really exists,” she told Fox News Digital.
“And that just infuriates me.”
Today, McFadden’s goal is to raise awareness of chronic insomnia — “because there are so many people in this world who are suffering from this.”
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Lurking dementia risk exposed by breakthrough test 25 years before symptoms
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A new blood test could determine a woman’s dementia risk as early as 25 years before symptoms emerge.
That’s according to new research from the University of California San Diego, which found that a specific biomarker protein associated with early pathological processes of Alzheimer’s disease was “strongly linked” to future dementia risk.
The researchers analyzed blood samples from 2,766 participants in the Women’s Health Initiative Memory Study in the late 1990s, according to the study’s press release.
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The women ranged from 65 to 79 years of age and showed no signs of cognitive decline at the start of the study.
After tracking the participants for up to 25 years, the researchers concluded that the biomarker phosphorylated tau 217 (p-tau217) was “strongly associated” with future mild cognitive impairment and dementia.
A new blood test could determine a woman’s dementia risk as early as 25 years before symptoms emerge. (iStock)
Women who had higher levels of p-tau217 at the beginning of the study were “much more likely” to develop the disease. The findings were published today in JAMA Network Open.
“The key takeaway is that our study suggests it may be possible to detect risk of dementia two decades in advance using a simple blood test in older women,” first author Aladdin H. Shadyab, a UC San Diego associate professor of public health and medicine, told Fox News Digital.
“These biomarkers may help us identify who is at greatest risk and develop strategies to delay or prevent dementia.”
“Our findings show that the blood biomarker p-tau217 could help identify individuals at higher risk for dementia long before symptoms begin,” he added.
This long lead time could open the door to earlier prevention strategies and more targeted monitoring, rather than waiting until memory problems are already affecting daily life, according to Shadyab.
A specific biomarker protein associated with early pathological processes of Alzheimer’s disease was “strongly linked” to future dementia risk. (iStock)
“As the research advances, these biomarkers may help us identify who is at greatest risk and develop strategies to delay or prevent dementia,” he said.
This risk relationship wasn’t the same across the board, however. Women over 70 with higher p-tau217 levels had “poorer cognitive outcomes” compared to those under 70, as did those with the APOE ε4 gene, which is a known risk factor for Alzheimer’s disease.
The study also found that p-tau217 was a stronger predictor of dementia in women who were randomly assigned to receive estrogen and progestin hormone therapy compared to those who received a placebo.
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“Blood-based biomarkers like p-tau217 are especially promising because they are far less invasive and potentially more accessible than brain imaging or spinal fluid tests,” said senior author Linda K. McEvoy, senior investigator at Kaiser Permanente Washington Health Research Institute and professor emeritus at the Herbert Wertheim School of Public Health, in the release.
“Blood-based biomarkers like p-tau217 are especially promising because they are far less invasive and potentially more accessible than brain imaging or spinal fluid tests,” a researcher said. (iStock)
“This is important for accelerating research into the factors that affect the risk of dementia and for evaluating strategies that may reduce risk.”
Blood tests for Alzheimer’s disease are still being studied and are not recommended for routine screening in people without symptoms, Shadyab noted.
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More research is needed before this approach can be considered for clinical use prior to cognitive symptoms.
Future studies should investigate how other factors — like genetics, hormone therapy and age-related medical conditions — might interact with plasma p-tau217, the researchers added.
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“The study examined only older women, so the findings may not necessarily apply to men or younger populations,” Shadyab noted. “We also examined overall dementia outcomes rather than specific subtypes such as Alzheimer’s disease.”
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Key fitness measure is strong predictor of longevity after certain age, study finds
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For women over 60, muscle strength plays a critical role in longevity, a new study confirms.
Researchers at the University at Buffalo, New York, followed more than 5,000 women between the ages of 63 and 99, finding that those with greater muscle strength had a significantly lower risk of death over an eight-year period.
The findings were published in JAMA Network Open.
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Muscle function was measured using grip strength and how quickly participants could complete five unassisted sit-to-stand chair raises.
These are two tests commonly used in clinical settings to evaluate muscle function in older adults, the researchers noted.
A recent study shows that stronger muscle strength in women over 60 is linked to a lower risk of death over eight years. (iStock)
“In a community cohort of ambulatory older women, muscular strength was associated with significantly lower mortality rates, even when we accounted for usual physical activity and sedentary time measured using a wearable monitor, gait speed and blood C-reactive protein levels,” study lead author Michael LaMonte, research professor of epidemiology and environmental health at the University at Buffalo, told Fox News Digital.
“Movement is the key — just move more and sit less.”
Many earlier studies did not include those objective measurements, making it difficult to determine whether muscle strength itself was linked to longevity, according to LaMonte. “Our study was able to better isolate the association between strength and death in later life,” he added.
Even for women who don’t get the recommended amount of aerobic physical activity, which is at least 150 minutes per week, muscle strength remained important for longevity, the researchers found.
Women with greater muscle strength were more likely to live longer, even if they did not meet the recommended amount of aerobic exercise. (iStock)
“The findings of lower mortality in those who had higher strength but were not meeting current national guidelines on aerobic activity were somewhat intriguing,” LaMonte said.
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Federal guidelines recommend strengthening activities one to two days per week, targeting major muscle groups.
Resistance training does not have to require a gym membership, LaMonte noted. These exercises can be performed using free weights, resistance bands, bodyweight movements or even household items, such as soup cans.
Experts recommend working major muscle groups one or two days a week using weights, bands or bodyweight exercises. (iStock)
“Movement is the key — just move more and sit less,” he said. “When we can no longer get out of the chair and move around, we are in trouble.”
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LaMonte acknowledged several limitations of the study. The researchers assessed muscle strength in older age but did not explore how earlier levels in adulthood might influence long-term health outcomes.
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“We were not able to understand how strength and mortality relate in younger ages,” he said, noting that future research should explore whether building strength earlier could have an even greater impact on longevity.
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