Health
Simple food combo may outperform omega-3 supplements for reducing inflammation
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A simple dietary pairing could offer broader immune benefits than omega-3s alone.
Researchers at the University of Nottingham found that pairing kefir with a prebiotic fiber mix led to greater reductions in inflammation markers than omega-3 supplements or fiber alone.
The findings, published in the Journal of Translational Medicine, suggest that supporting gut bacteria may play an important role in immune and metabolic function.
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Kefir is a fermented milk drink similar to yogurt that contains live bacteria and yeast.
Drinking kefir and taking fiber together may help lower inflammation more effectively than omega-3 supplements. (iStock)
When kefir was combined with prebiotic fiber, researchers observed a stronger effect. Prebiotic fiber feeds healthy bacteria in the gut, helping them grow and function more effectively, the study explained.
As those beneficial bacteria thrive, they produce natural substances that help calm inflammation in the body.
In the six-week study, people who took the kefir-and-fiber combination showed the biggest drop in markers linked to whole-body inflammation.
Those who took omega-3 supplements or fiber alone also improved, but not to the same degree, the study suggested.
Over six weeks, those taking kefir and fiber saw the largest drop in inflammation markers, while omega-3 or fiber alone produced smaller reductions. (iStock)
“Our study shows that while all three dietary approaches reduced inflammation, the synbiotic — combining fermented kefir with a diverse prebiotic fiber mix — had the most powerful and wide-ranging effects,” said Amrita Vijay, a gut microbiome scientist who led the research.
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The researchers measured systemic inflammatory markers, which indicate inflammation occurring throughout the body.
Inflammation is a normal immune response, but chronic, low-level inflammation that persists over time has been linked to conditions such as heart disease and metabolic conditions, according to Cleveland Clinic.
Throughout the study, researchers monitored blood markers to track changes in whole-body inflammation. (iStock)
The findings suggest that combining probiotics and prebiotics may provide broader support than relying on a single supplement.
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“This suggests that the interaction between gut microbes and dietary fiber may be key to supporting immune balance and metabolic health,” Vijay said.
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The team plans to further investigate how synbiotic supplementation may affect individuals with chronic inflammatory disorders.
Health
Common vaccine slashes Alzheimer’s disease risk when dose is increased
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A new, stronger flu shot could slash Alzheimer’s risk in half, according to new data.
The study, led by researchers at the University of Texas Health Science Center at Houston (UTHealth), found that adults 65 and older who received a high-dose influenza vaccine had a significantly lower risk of developing Alzheimer’s disease compared to those who received the standard dose.
The immune system naturally weakens with age, making older adults less responsive to standard vaccines. To combat this, the Centers for Disease Control and Prevention recommends a high-dose flu vaccine for people over 65. This version is approximately four times stronger than the standard shot.
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Alzheimer’s disease, a brain disorder that slowly destroys memory and thinking skills, affects more than 6 million Americans, most of them age 65 or older.
Dr. Marc Siegel, a Fox News senior medical contributor, weighed in on the impact of the flu shot on Alzheimer’s risk.
Alzheimer’s disease, a brain disorder that slowly destroys memory and thinking skills, affects more than 6 million Americans, most of them age 65 or older. (iStock)
As the vaccine directly affects the immune system, it is possible that this interaction could decrease inflammation in the body and “thereby indirectly decrease Alzheimer’s risk,” Siegel, who was not involved in the research, told Fox News Digital.
“Flu shots and their components do not cross the blood-brain barrier, meaning they aren’t directly affecting brain cells.”
“We can’t conclude from this that it is the flu shot itself that causes the effect.”
“I was stunned that, as a physician, I didn’t know a higher dose was offered,” lead study author Paul Schulz, professor of neurology at McGovern Medical School at UTHealth, said in a press release.
Schulz also led a previous study linking general flu vaccination to a 40% reduction in Alzheimer’s risk.
While the previous research had already linked general flu vaccination to a reduction in Alzheimer’s risk, this new study looked specifically at the strength of the dose.
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“The public health department had seen our vaccine research and asked if I could come down to talk to them about it,” said Schulz. “We went through the findings, and they asked if there was a difference with different dosages; I was confused.”
Adults who received the quadruple-strength vaccine had a lower risk of Alzheimer’s than those who received the standard dose. (iStock)
After sorting through data from nearly 200,000 older adults, the team found the adults who received the high-dose vaccine had a lower risk of Alzheimer’s than those who received the standard dose.
Adults in the high-dose group had an almost 55% lower risk than those who weren’t vaccinated, significantly outperforming standard-dose protection.
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The protective effect of the high-dose vaccine was even more pronounced in women compared to men, although both groups saw significant benefits.
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This study shows a link, not a cause, the researchers noted.
Experts can’t say for certain that the flu shot itself stopped Alzheimer’s because people who get high-dose vaccines might also have other healthy habits, like better diets or more frequent check-ups.
The study focused on people over 65, so it’s unclear whether getting these shots earlier in life would provide the same level of protection. (iStock)
The researchers also looked at medical records after the fact, rather than following two controlled groups in real time, which can sometimes result in missing information or biases.
“This is not a cause/effect study,” Siegel reiterated. “We can’t conclude that the flu shot itself causes the effect; it could be something about the people who decide to take this shot.”
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The study also focused on people over 65, so it’s unclear whether getting these shots earlier in life would provide the same level of protection.
“This needs to be further studied, but it is already certainly another reason to take a flu shot,” Siegel added.
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The study was published in the journal Neurology.
Health
Woman discovers missing nose ring traveled to her lungs, causing month-long cough
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A TikToker in Mexico thought her cough that wouldn’t go away was just a reaction to the changing weather. Instead, it was her own nose ring, lodged deep within her lungs.
The 26-year-old, Monica Deyanira Cabrera Barajas, recently went viral on TikTok, amassing 4.7 million views after revealing the freak medical accident.
In videos, she shared that the stray accessory sat a mere 0.5 millimeters from her aorta, Jam Press reported.
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Deyanira, who has a large number of piercings, didn’t initially notice the jewelry was missing. It wasn’t until she developed a “chronic cough” lasting over a month that she went to see a doctor.
“The only theory I have, which I told the pulmonologist, is that I fell asleep, the little ball fell out, and that was it,” Deyanira told creatorzine.com.
What was supposed to be a routine 20-minute extraction turned into a high-stakes medical procedure. (Jam Press)
“I was lying on my back, I didn’t realize, and that’s how I messed up.”
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What was supposed to be a routine 20-minute extraction turned into a high-stakes medical procedure. During the initial attempt, surgeons were unable to budge the object because it had already begun attaching to her internal tissue.
“It ended up taking an hour and 20 minutes, and they still couldn’t remove it because it was attached to my body,” she said, according to the Jam Press report.
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Facing a second, more invasive surgery and the risk of a fatal hemorrhage, Deyanira prepared for the worst. The night before the surgery, she wrote a farewell letter to her loved ones.
The nose ring was lodged dangerously close to her aorta, the body’s primary artery. (Jam Press)
“I was honestly thinking, ‘I’m going to die,’” she said. “It’s a horror I wouldn’t wish on anyone.”
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The woman’s surgeon was equally stunned by how close the metal was to her heart. According to Deyanira, the doctor told her, “It seems God takes care of his creatures.”
If the metal had punctured her lung or heart before doctors discovered it, Deyanira said she likely would have died from a lung collapse or perforated aorta.
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Now, the TikToker says her days of septum rings are over.
After the ordeal, Deyanira said she’s permanently done with piercings. (Jam Press)
“I love piercings, and I really liked my septum piercing, but in my case, I wouldn’t get it again because of the terror I experienced,” she said.
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Followers commented that the ordeal “unlocked a fear I didn’t know I had.”
Health
Inside a One-Man Workshop for Ultrapotent Drugs
Last fall, a man who calls himself Chemical Analyst allowed the two of us – New York Times reporters writing about the illegal drug trade – to watch on a secure video call as he packaged ultrapotent synthetic drugs for distribution.
These chemicals now flood the modern drug market. Many have psychoactive effects that are much more intense than those of traditional drugs. One newly emerging drug, cychlorphine, can be 250 to 500 times as strong as heroin and 10 times as strong as fentanyl.
Chemical Analyst is a small-time, independent dealer who supplies powerful drugs without a cartel or gang for support. From an apartment in the northeastern United States, he places online orders for drugs made in a lab in China, repackages them and sells them domestically.
Operations like this represent the frontier of a drug market that is increasingly democratized. Compounds can be made in labs all over the world, ordered online and shipped anywhere. And because these drugs are often entirely new chemical compounds, they are difficult for law enforcement officials to detect.
We interviewed Chemical Analyst over the course of a year, after meeting him through others who use and sell these new, potent drugs.
He allowed The Times to observe his operation on the condition that his identity would remain confidential. He is a felon on probation who fears further prosecution. He is also a functional addict who regularly buys, sells and ingests some of the most potent drugs in the world.
The Times decided to describe parts of his process because they are vital to understanding both the origins of ultrapotent drugs and the difficulties faced by law enforcement in tracking and interdicting these new compounds.
In 2022 and 2023, Chemical Analyst was a street dealer of fentanyl and crack. His setup at an apartment “is so much safer,” he said. “I don’t have to worry about running if a cop rolls up through the alley,” he added. As his own use gravitated to more potent drugs, he developed the connections and expertise to sell them, too.
His latest drugs arrived in mid-October from China in a silver Mylar bag. He paid $4,370 in cryptocurrency for the shipment, which contained several powerful and potentially deadly synthetic compounds.
One bag held a 100-gram slab of MD-PiHP. The drug is a cathinone, a class of stimulants often sold as “bath salts” that can induce psychosis. In markets where these stimulants are particularly popular, like Miami, they are increasingly showing up in toxicology reports from people who suffer fatal overdoses.
On the secure video call, Chemical Analyst measured 100-milligram crystals of the drug into small bags. He sprayed the bags with bleach to remove his DNA, applied labels from an untraceable thermal printer and wore textured latex gloves to keep the bags clean of fingerprints. Because Chemical Analyst is a convicted felon, his prints are already in state databases.
He moved the drugs into smaller baggies and weighed them. He then sealed them into packages for shipment. He wrote a false return address so he could not be traced and drove far from his residence to drop them in the mail.
Chemical Analyst said that people might assume he sold on the “darknet,” a restricted network that requires special software to access. But he has a website on the regular internet, and he takes steps to conceal his whereabouts and identity. He accepts cryptocurrency payments, but he avoids Bitcoin because he worries that it might be trackable.
Drugs like this are hard to police in part because their composition changes all the time. The molecular structure of MD-PiHP is nearly identical to that of MDPV, a potent cathinone that appeared in 2010 and can cause extreme psychosis and death.
Chemical Analyst spoke in detail about the chemistry of these novel drugs. He offered to draw MD-PiHP to show important facets of its structure; shortly after the video call, he texted his illustration.
Chemical Analyst first spotted an online listing for the drug in early 2025. He is familiar enough with drug molecules that the structure alone made him want to try it. He was surprised by its potency and effects. “This is not something humans should be getting high on,” he said, adding an expletive.
He worried that the drug’s potency could produce a high so intense that it “could easily cause anhedonia,” an inability to experience joy when sober. He said that, unlike other suppliers, he did not adulterate his products, so they were predictable and therefore safer. “It’s how I pay the bills,” he said.
His operation also shows just how inexpensive illicit drugs have become in the age of synthetics. In his recent shipment from China, he ordered half a dozen different substances, paying between $6 and $28 for a pure gram, depending on the drug. A standard dose is 50 to 100 milligrams, meaning that the cost of getting high is often less than $1.
He keeps a collection of novel drug samples, as well as a separate stash for his own consumption.
Chemical Analyst plays another important role in the emergence of ultrapotent synthetic drugs. He is part of a small but influential circle of armchair chemists and theorists who discuss ideas for new drugs and scour medical literature for forgotten molecules.
He said that some members of these groups interacted with Chinese manufacturers to discuss new drug ideas. “They get ideas from us,” he said. “We have direct contact with them.”
A source at a Chinese drug manufacturer confirmed to The Times that new drug ideas were introduced first to small dealers and users like Chemical Analyst to test their popularity. If a drug catches on, it might be introduced to the mass market, which continues to rapidly transform.
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