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Common vaccine slashes Alzheimer’s disease risk when dose is increased

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Common vaccine slashes Alzheimer’s disease risk when dose is increased

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A new, stronger flu shot could slash Alzheimer’s risk in half, according to new data.

The study, led by researchers at the University of Texas Health Science Center at Houston (UTHealth), found that adults 65 and older who received a high-dose influenza vaccine had a significantly lower risk of developing Alzheimer’s disease compared to those who received the standard dose.

The immune system naturally weakens with age, making older adults less responsive to standard vaccines. To combat this, the Centers for Disease Control and Prevention recommends a high-dose flu vaccine for people over 65. This version is approximately four times stronger than the standard shot.

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Alzheimer’s disease, a brain disorder that slowly destroys memory and thinking skills, affects more than 6 million Americans, most of them age 65 or older.

Dr. Marc Siegel, a Fox News senior medical contributor, weighed in on the impact of the flu shot on Alzheimer’s risk.

Alzheimer’s disease, a brain disorder that slowly destroys memory and thinking skills, affects more than 6 million Americans, most of them age 65 or older. (iStock)

As the vaccine directly affects the immune system, it is possible that this interaction could decrease inflammation in the body and “thereby indirectly decrease Alzheimer’s risk,” Siegel, who was not involved in the research, told Fox News Digital.

“Flu shots and their components do not cross the blood-brain barrier, meaning they aren’t directly affecting brain cells.”

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“We can’t conclude from this that it is the flu shot itself that causes the effect.”

“I was stunned that, as a physician, I didn’t know a higher dose was offered,” lead study author Paul Schulz, professor of neurology at McGovern Medical School at UTHealth, said in a press release.

Schulz also led a previous study linking general flu vaccination to a 40% reduction in Alzheimer’s risk.

While the previous research had already linked general flu vaccination to a reduction in Alzheimer’s risk, this new study looked specifically at the strength of the dose.

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“The public health department had seen our vaccine research and asked if I could come down to talk to them about it,” said Schulz. “We went through the findings, and they asked if there was a difference with different dosages; I was confused.”

Adults who received the quadruple-strength vaccine had a lower risk of Alzheimer’s than those who received the standard dose. (iStock)

After sorting through data from nearly 200,000 older adults, the team found the adults who received the high-dose vaccine had a lower risk of Alzheimer’s than those who received the standard dose.

Adults in the high-dose group had an almost 55% lower risk than those who weren’t vaccinated, significantly outperforming standard-dose protection.

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The protective effect of the high-dose vaccine was even more pronounced in women compared to men, although both groups saw significant benefits.

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This study shows a link, not a cause, the researchers noted.

Experts can’t say for certain that the flu shot itself stopped Alzheimer’s because people who get high-dose vaccines might also have other healthy habits, like better diets or more frequent check-ups.

The study focused on people over 65, so it’s unclear whether getting these shots earlier in life would provide the same level of protection. (iStock)

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The researchers also looked at medical records after the fact, rather than following two controlled groups in real time, which can sometimes result in missing information or biases.

“This is not a cause/effect study,” Siegel reiterated. “We can’t conclude that the flu shot itself causes the effect; it could be something about the people who decide to take this shot.”

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The study also focused on people over 65, so it’s unclear whether getting these shots earlier in life would provide the same level of protection.

“This needs to be further studied, but it is already certainly another reason to take a flu shot,” Siegel added.

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The study was published in the journal Neurology.

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Micro-Walking Plan for Weight Loss: Harvard Doctor Calls It a ‘Wonder Drug’

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Micro-Walking Plan for Weight Loss: Harvard Doctor Calls It a ‘Wonder Drug’


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Micro-Walking Plan for Weight Loss That Burns Calories Fast




















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Possible hantavirus case under investigation in upstate New York; no connection to deadly cruise ship outbreak

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Possible hantavirus case under investigation in upstate New York; no connection to deadly cruise ship outbreak

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A “suspected” hantavirus case in upstate New York is being investigated, according to the Ontario County Public Health Department (OCPHD) based in Canandaigua.

The department announced in a Facebook post Thursday that it is currently “investigating a suspected locally acquired hantavirus case.”

“There is NO connection to the cruise ship outbreak, and there is no risk to the general public,” OCPHD officials wrote.

The investigation comes as global health officials continue monitoring a rare hantavirus outbreak tied to the MV Hondius luxury cruise ship that has sickened multiple passengers and crew members and left three people dead.

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AMERICAN EVACUATED FROM CRUISE SHIP TESTS POSITIVE FOR HANTAVIRUS, ANOTHER HAS SYMPTOMS, HHS CONFIRMS

As of May 13, the World Health Organization (WHO) said 11 hantavirus cases had been identified in connection with the cruise outbreak, including eight confirmed cases, two probable cases and one inconclusive case. Three deaths have also been linked to the outbreak.

Health officials have emphasized that hantavirus infections remain rare and that the risk to the general public is low.

Human-to-human transmission of hantavirus is considered extremely rare and has only been suspected in certain strains, including the Andes hantavirus strain linked to the cruise ship outbreak.

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A passenger wearing a face mask and blue protective gown gives a thumbs up inside a bus after disembarking from the hantavirus-stricken cruise ship MV Hondius at the port of Granadilla in Tenerife, Canary Islands, Spain, on May 10. (Manu Fernandez/AP Photo)

“Hantavirus infections are rare in New York,” the OCPHD said. “The virus is spread through mouse and rodent droppings, especially when urine, feces, or nesting materials become aerosolized during cleaning.”

The OCPHD urged residents to take precautions when cleaning enclosed spaces where rodents may be present, including wearing gloves and masks when opening or cleaning attics, cabins, sheds and garages.

The OCPHD and the Centers for Disease Control and Prevention (CDC) did not immediately respond to Fox News Digital’s request for comment.

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A 3D illustration shows the structure of hantavirus, an RNA virus transmitted to humans through rodent excreta that can cause severe illnesses including hemorrhagic fever, renal disease and hantavirus pulmonary syndrome. (iStock)

The cruise ship outbreak has prompted heightened precautions internationally.

In the Netherlands, Radboud University Medical Center quarantined 12 staff members after officials said a hantavirus patient’s blood and urine were not handled under the strictest international protocols required for the specific virus strain.

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Hospital officials said the risk of infection to staff remained low but called the quarantine a precautionary measure.

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The outbreak aboard the MV Hondius began after a Dutch cruise ship carrying 147 passengers and crew departed Argentina on April 1 for a South Atlantic voyage.

According to the WHO, investigators believe the initial infection may have stemmed from rodent exposure during birdwatching excursions before boarding the ship.

Fox News Digital’s Bonny Chu contributed to this report.

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Cancer-related brain fog may improve with 2 simple treatments, scientists say

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Cancer-related brain fog may improve with 2 simple treatments, scientists say

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A common over-the-counter medication combined with a home exercise program could help ease cognitive issues for cancer patients.

That’s according to a study from the University of Rochester, which tested the effects of physical activity and low-dose ibuprofen on patients receiving chemotherapy treatment.

“Chemo brain” (also called chemotherapy-related cognitive impairment, or CRCI) is a known side effect of cancer treatment that can affect memory, concentration and multitasking ability. Up to 80% of people who receive chemo experience some degree of cognitive impairment, previous studies have shown.

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Rochester’s phase 2 trial studied 86 adult cancer patients in New York undergoing chemotherapy who were experiencing cognitive problems. The average age was 53 and nearly 89% of participants were women, according to a university press release.

Participants who took only ibuprofen also showed greater cognitive improvements than the placebo group. (IStock)

Patients were randomly assigned to one of four groups. One group participated in home exercise designed specifically for cancer patients, a second group combined the exercises with ibuprofen (200 milligrams, or one pill, twice a day), the third group took ibuprofen alone and a fourth took a placebo alone.

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The exercise program consisted of low to moderate-intensity activity, including progressive walking and training with resistance bands.

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“This is one of the first studies specifically designed to assess these interventions for cancer-related cognitive impairment during chemotherapy in patients with multiple diseases using both performance-based cognitive assessments and patient-reported outcomes,” said lead author Michelle C. Janelsins, Ph.D., MPH, of the University of Rochester and the Wilmot Cancer Institute, in the press release.

Up to 80% of people who receive chemo experience some degree of cognitive impairment.

After six weeks, exercise was linked to the clearest improvements in attention and cognitive function, according to input from family and friends. Those in the group who combined exercise and placebo showed better attention levels compared to those who took just a placebo.

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Participants who took only ibuprofen also showed greater cognitive improvements than the placebo group.

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The findings suggest that ibuprofen may provide some improvement in cognitive function, although the benefits appeared to be smaller and less consistent than those seen with exercise.

“Chemo brain” (also called chemotherapy-related cognitive impairment, or CRCI) is a known side effect of cancer treatment that can affect memory, concentration and multitasking ability.  (iStock)

This suggests that inflammation may contribute to cancer-related cognitive impairment, and that anti-inflammatory medications could be an effective therapeutic approach.

“We are encouraged by the findings of this trial that suggest possible benefits of both interventions for some cognitive domains,” Janelsins said. “Clearly, we saw a more pronounced effect with exercise, which is notable considering the multiple health benefits of exercise for cancer survivors.”

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No adverse side effects were reported during the trial.

The findings were published in Cancer, the peer-reviewed journal of the American Cancer Society.

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There were some limitations of the study, the researchers noted, including the small sample size and short duration. The effects were also not consistent across every measure of cognitive function.

As the majority of participants were women, the findings may not be generalized to broader populations.

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“Clearly, we saw a more pronounced effect with exercise, which is notable considering the multiple health benefits of exercise for cancer survivors,” the researcher said. (iStock)

Researchers are planning larger phase 3 trials to confirm whether ibuprofen and exercise can effectively improve chemo-related cognitive impairment.

“Since we saw cognitive benefits in some domains and not others, we will also consider additional doses and longer durations in future research trials,” said Janelsins.

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Investigators emphasized that patients should speak with their oncology team before starting ibuprofen or exercise interventions during chemotherapy, as certain treatments or medical conditions could increase the risk of side effects and complications.

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