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Common vaccine slashes Alzheimer’s disease risk when dose is increased

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Common vaccine slashes Alzheimer’s disease risk when dose is increased

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A new, stronger flu shot could slash Alzheimer’s risk in half, according to new data.

The study, led by researchers at the University of Texas Health Science Center at Houston (UTHealth), found that adults 65 and older who received a high-dose influenza vaccine had a significantly lower risk of developing Alzheimer’s disease compared to those who received the standard dose.

The immune system naturally weakens with age, making older adults less responsive to standard vaccines. To combat this, the Centers for Disease Control and Prevention recommends a high-dose flu vaccine for people over 65. This version is approximately four times stronger than the standard shot.

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Alzheimer’s disease, a brain disorder that slowly destroys memory and thinking skills, affects more than 6 million Americans, most of them age 65 or older.

Dr. Marc Siegel, a Fox News senior medical contributor, weighed in on the impact of the flu shot on Alzheimer’s risk.

Alzheimer’s disease, a brain disorder that slowly destroys memory and thinking skills, affects more than 6 million Americans, most of them age 65 or older. (iStock)

As the vaccine directly affects the immune system, it is possible that this interaction could decrease inflammation in the body and “thereby indirectly decrease Alzheimer’s risk,” Siegel, who was not involved in the research, told Fox News Digital.

“Flu shots and their components do not cross the blood-brain barrier, meaning they aren’t directly affecting brain cells.”

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“We can’t conclude from this that it is the flu shot itself that causes the effect.”

“I was stunned that, as a physician, I didn’t know a higher dose was offered,” lead study author Paul Schulz, professor of neurology at McGovern Medical School at UTHealth, said in a press release.

Schulz also led a previous study linking general flu vaccination to a 40% reduction in Alzheimer’s risk.

While the previous research had already linked general flu vaccination to a reduction in Alzheimer’s risk, this new study looked specifically at the strength of the dose.

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“The public health department had seen our vaccine research and asked if I could come down to talk to them about it,” said Schulz. “We went through the findings, and they asked if there was a difference with different dosages; I was confused.”

Adults who received the quadruple-strength vaccine had a lower risk of Alzheimer’s than those who received the standard dose. (iStock)

After sorting through data from nearly 200,000 older adults, the team found the adults who received the high-dose vaccine had a lower risk of Alzheimer’s than those who received the standard dose.

Adults in the high-dose group had an almost 55% lower risk than those who weren’t vaccinated, significantly outperforming standard-dose protection.

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The protective effect of the high-dose vaccine was even more pronounced in women compared to men, although both groups saw significant benefits.

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This study shows a link, not a cause, the researchers noted.

Experts can’t say for certain that the flu shot itself stopped Alzheimer’s because people who get high-dose vaccines might also have other healthy habits, like better diets or more frequent check-ups.

The study focused on people over 65, so it’s unclear whether getting these shots earlier in life would provide the same level of protection. (iStock)

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The researchers also looked at medical records after the fact, rather than following two controlled groups in real time, which can sometimes result in missing information or biases.

“This is not a cause/effect study,” Siegel reiterated. “We can’t conclude that the flu shot itself causes the effect; it could be something about the people who decide to take this shot.”

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The study also focused on people over 65, so it’s unclear whether getting these shots earlier in life would provide the same level of protection.

“This needs to be further studied, but it is already certainly another reason to take a flu shot,” Siegel added.

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The study was published in the journal Neurology.

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Why Women Over 50 Are Obsessed With Fiber-Rich Foods for Weight Loss

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Why Women Over 50 Are Obsessed With Fiber-Rich Foods for Weight Loss


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Fiber-Rich Foods for Weight Loss Help Women Over 50 Burn Fat Fast




















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Secret to weight loss may be hiding in your gut, new study suggests

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Secret to weight loss may be hiding in your gut, new study suggests

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A specific gut microbe could help with long-term weight-loss goals.

New research published in the journal Nature Medicine tested whether a pasteurized (not live) gut bacterium, called Akkermansia muciniphila MucT, could help people keep weight off after losing it.

The study enrolled 90 overweight and obese adults from the Netherlands in an eight-week, low-energy diet where they were instructed to lose 8% of their body weight, according to a press release.

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The participants then started a 24-week weight-maintenance phase and were randomly assigned to take either the gut bacterium or a placebo.

People taking Akkermansia regained significantly less weight than those taking the placebo, the study found. (iStock)

People taking Akkermansia regained less weight than those taking the placebo, at an average of 2.6 pounds versus 7.1 pounds — a statistically significant difference, according to the study results.

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The researchers noted that the efficacy of the treatment depends on a person’s existing gut microbiome. There were no serious adverse events reported.

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The study’s short duration and small sample size may not be enough to prove long-term benefits, the team noted. Another limitation is that participants ate whatever they wanted instead of following a standardized diet.

The study enrolled 90 overweight and obese adults from the Netherlands in an eight-week, low-energy diet where they were instructed to lose 8% of their body weight. (iStock)

Dr. Peter Balazs, MD, a hormone and weight loss specialist practicing in New York and New Jersey, called this a “well-designed” trial.

“The finding that a single gut microbe, pasteurized Akkermansia, significantly reduced weight regain is particularly compelling,” the expert, who was not involved in the research, told Fox News Digital. “Most probiotics have demonstrated far less efficacy, making these results especially noteworthy.”

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Balazs pointed out that pasteurized Akkermansia isn’t a live probiotic, but works through “components of the bacteria, particularly a protein called Amuc_1100.”

Akkermansia is “not a miracle pill,” an expert noted, although the study results are promising. (iStock)

“This protein helps strengthen the gut barrier, reduce low-grade inflammation and support healthy metabolic function,” he said. “After weight loss, the body naturally tries to regain fat, but Akkermansia appears to help quiet some of those biological signals, making it easier to maintain results over time.”

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While the study results are promising, the doctor cautioned that Akkermansia is not a miracle pill.

“It helps with maintenance, not initial loss,” he said. “Long-term use is plausible; however, it hasn’t been proven beyond 24 weeks. This does not replace diet, exercise or medical advice.”

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Dirty soda drinks are everywhere, but doctors warn of health risks: ‘Metabolic disaster’

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Dirty soda drinks are everywhere, but doctors warn of health risks: ‘Metabolic disaster’

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The latest beverage trend is far from clean – and it’s raising red flags with doctors.

Known as a “dirty soda,” it’s a soft drink that also includes a combination of added ingredients, such as flavored syrups, creamers, fruit juices and other garnishes. The result is a sweet beverage that’s a combination of a soda, mocktail and dessert.

Dirty sodas can easily deliver 250-400 calories and 55-70 grams of sugar in a single drink – which is often more than double the American Heart Association’s daily added sugar limit, according to Erin Palinski-Wade, a New Jersey-based registered dietitian.

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“It’s more like a dessert beverage than a soft drink, even if people use diet soda as the base,” she told Fox News Digital.

The drinks are most dangerous for those with insulin resistance, prediabetes or diabetes, Palinski-Wade warned.

A dirty soda is a soft drink that also includes a combination of added ingredients, such as flavored syrups, creamers, fruit juices and other garnishes. (iStock)

“The combination of rapidly absorbed sugar plus cream can cause sharp blood sugar spikes and crashes, driving hunger, fatigue and higher insulin demands,” she cautioned.

The trend is said to have originated in Utah years ago at a specialty soda shop, Swig, reportedly due to people in the Mormon faith seeking an alternative to coffee. The drink was then popularized by social media and TV shows, such as “The Secret Lives of Mormon Wives,” according to Eater.com.

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The dirty soda trend is widely credited to Swig, a Utah-based soda shop founded in 2010. The concept reportedly gained popularity in Utah, where many members of The Church of Jesus Christ of Latter-day Saints abstain from coffee and alcohol, helping create demand for customizable, non-alcoholic drinks.

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“There are multiple soda shops in most suburbs here,” one Utah resident wrote on Reddit. “I have many coworkers who stop at one daily on their way to work [because] they don’t drink coffee, but will drink dirty sodas.”

Trend goes mainstream

Dirty sodas have recently grown in popularity, appearing on many restaurant menus and grocery store shelves. Coca-Cola has launched its Coca-Cola Cherry Float, which is designed to mimic the soda-and-cream experience, while PepsiCo offers a Dirty Mountain Dew Cream Soda.

McDonald’s, Taco Bell, Sonic and Dunkin are among the fast-food brands that include dirty soda options in their beverage line-ups.

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Crumbl recently launched a dirty soda that includes multiple sweet ingredients on top of an already sugary soda base. (USA TODAY Network via Reuters Connect)

Perhaps taking the cake is Crumbl, which recently launched a dirty soda that includes multiple sweet ingredients on top of an already sugary soda base.

“Crumbl needs to be stopped,” Dr. Mark Hyman wrote in a recent social media post. “Their new ‘dirty soda’ contains 186 grams of sugar, the equivalent of eating 19 Krispy Kreme donuts. This is a metabolic disaster and should be illegal.”

Experts warn of health risks

Dr. Marc Siegel, Fox News senior medical analyst, echoed the warnings about dirty sodas being “very unhealthy.”

“They are loaded with processed sugar, empty calories and saturated fats,” he told Fox News Digital. “They are also highly addictive, especially because of the high sugar content, and are about 400 calories per serving.”

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Over time, regular consumption of these types of sugary beverages can train the brain to seek repeated dopamine and endorphin releases, Siegel warned. This can increase the risk of obesity, diabetes, heart disease, dementia and other chronic illnesses.

An employee prepares a dirty soda at Floso, a drink shop in Salem, Oregon, in July 2024. (Abigail Dollins/Statesman Journal)

Tanya Freirich, a registered dietitian nutritionist in Charlotte, North Carolina, echoed that daily added sugars increase the risk of obesity, non-alcoholic fatty liver disease, cardiovascular disease and diabetes.

“Additionally, the creamy mix-ins featured in dirty sodas are generally high in saturated fat, another nutrient that should be consumed in limited amounts,” Freirich told Fox News Digital.

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“If you’re looking for a mocktail or fun non-alcoholic beverage, consider using a base of plain seltzer water for a bubbly drink,” she recommended. “Even with the same add-ins, your end result will contain considerably less sugar, but still taste sweet.”

An orange dirty soda is displayed at the Ross County Fair in Ross County, Ohio. (USA TODAY Network via Reuters Connect)

Kenneth J. Perry, M.D., an emergency physician in Charleston, South Carolina, also noted that dirty sodas represent a continuation of the trend toward highly sugary beverages.

“Their effects are short-lived, prompting individuals to consume excessive amounts,” he warned. “This combination of low nutritional value, high sugar content and poor satiety can have significant health implications.”

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Each additional highly sugary beverage consumed daily increases the risk of developing diabetes, high blood pressure or heart disease, Perry cautioned.

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The World Health Organization recommends limiting free sugars – such as those found in beverages with added sugar – to less than 10% of total daily energy consumption, the doctor noted.

“Beverages with added sugar are one of the most easily modifiable risk factors for various downstream health issues,” Perry added.

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For those who do decide to try the dirty soda trend, Palinski-Wade recommends choosing a small size, using a diet soda base and limiting it to a rare treat.

“It really belongs in the same category as a cake or a milkshake – occasionally, and in smaller portions.”

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