Fitness
Exercise Scientist Warns That Overuse of this Everyday Medication Can Cause Kidney Damage
We’ve all been there, you have a heavy training session resulting in a few aches and niggles and reach for the Ibuprofen to ease some of the discomfort. And while it may be the simplest way to ward off workout related woes, the everyday medication comes with its risks according to exercise scientist, Dr Mike Israetel PhD.
In an Instagram reel, Israetel critiques Alan Ritchson’s diet and training routine, and in the process, comments on the actor’s negative experience taking ibuprofen or NSAIDs (nonsteroidal anti-inflammatory drugs) during a heavy training phase. Israetel warns, ‘Probably the number of people who have done acute damage to their bodies in medically relevant ways from Ibuprofen is on par for that with anabolic steroids’
In the video Israetel is critiquing, Ritchson shares, ‘I thought that would kind of be a magic bullet if I got strict and had a nutritionist and it still didn’t help the issues I was facing, which was due to a medicine I was taking, an NSAID.’
Israetel interjects, ‘Holy fuck. Big, big problem. People with very physically demanding roles, they get into some joint connective tissue pain, they take non steroidal anti inflammatory drugs, NSAIDs, Advil like that — Ibuprofen as you know it around the world. And higher doses of these for long durations, anything over 600 mg for anything over like a week can in many cases do some gnarly debit carding to your kidneys, and it’s not good for a variety of other shit.’
He continues to explain, ‘Just because you can buy Advil over the counter and just gulp it down and we feel better for six hours, doesn’t mean it’s something you should be doing multiple times a day every day for a long time. People do that and they sometimes get into real serious trouble.’
This stark warning is supported by evidence. In a review published in Pharmacology Research and Perspectives, it notes that NSAIDs like Ibuprofen at higher doses, particularly doses exceeding 1200 mg per day can cause kidney damage through mechanisms that interfere with normal kidney function.
If you are in doubt about your ibuprofen dosage for pain management, it’s important to be mindful and speak to your healthcare professional for additional support.
Kate is a fitness writer for Men’s Health UK where she contributes regular workouts, training tips and nutrition guides. She has a post graduate diploma in Sports Performance Nutrition and before joining Men’s Health she was a nutritionist, fitness writer and personal trainer with over 5k hours coaching on the gym floor. Kate has a keen interest in volunteering for animal shelters and when she isn’t lifting weights in her garden, she can be found walking her rescue dog.
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WEDNESDAY, Nov. 20, 2024 (HealthDay News) — High cardiorespiratory fitness (CRF) is associated with better cognitive performance and lower dementia risk, according to a study published online Nov. 19 in the British Journal of Sports Medicine.
Shuqi Wang, from the Tianjin Medical University in China, and colleagues examined the association of CRF with cognitive function and dementia risk, accounting for genetic predisposition for dementia. A total of 61,214 dementia-free participants within the U.K. Biobank, aged 39 to 70 years, were followed for up to 12 years. The CRF score was estimated using a six-minute submaximal exercise test and divided into age- and sex-standardized tertiles.
The researchers found that high CRF was associated with better global cognitive function compared with low CRF (β = 0.05). Overall, 553 individuals developed dementia during the follow-up period. The incidence rate ratio was 0.60 for all dementia for high CRF versus low CRF; dementia onset was delayed by 1.48 years among people with high versus low CRF. Higher CRF attenuated all dementia risk by 35 percent among those with a moderate/high polygenic risk score (incidence rate ratio, 0.65).
“Our findings suggest that maintaining favorable CRF could be a strategy for the prevention of dementia, even among people with a high genetic predisposition,” the authors write.
Abstract/Full Text
Fitness
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