Health
Pregnant woman and baby saved after doctors find grapefruit-sized tumor: 'Extremely rare'
A Chicago woman was just weeks away from giving birth when a nagging cough led to a shocking medical discovery.
MaKenna Lauterbach, then 26 years old, began experiencing severe coughing fits in the last three months of her pregnancy.
“They would be so severe that I would become winded and nauseous to the point of vomiting,” she told Fox News Digital.
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Lauterbach, who lives on a farm in Washburn, Illinois, also began noticing shortness of breath while tending to her horses and goats.
“I give hay to the horses every morning and noticed how winded I was becoming with a dry cough,” she said. “My body felt like I just ran two miles, when, in reality, I had only walked to the barn and back.”
MaKenna Lauterbach, pictured with her husband, Parker, and new baby, Colter, was diagnosed with stage 3 melanoma. (Northwestern Medicine)
Some doctors dismissed Lauterbach’s symptoms, she said, repeatedly telling her, “It’s because you are pregnant.”
Eventually, though, when the coughing led to vomiting, doctors performed scans and detected a large, grapefruit-sized tumor in her middle chest cavity and right lung, which was completely blocking the artery to the right lung.
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“It’s extremely rare to see this type of tumor invading into the major blood vessels of the heart,” said Chris Mehta, M.D. — a cardiac surgeon with the Northwestern Medicine Bluhm Cardiovascular Institute who specializes in complex heart reconstruction — in a press release.
“It’s extremely rare to see this type of tumor invading into the major blood vessels of the heart.”
“We may see something like this once every few years.”
The tumor had put Lauterbach — and her baby — into respiratory distress.
‘In real trouble’
Lauterbach was flown to Northwestern Memorial Hospital in Chicago, where a large medical team was waiting for her.
“MaKenna was in real trouble, and we had to act quickly – this wasn’t something that could wait for Monday morning,” said Lynn Yee, M.D., maternal-fetal medicine specialist at Northwestern Medicine, in the release.
Though he was born three weeks early, little Colter is a thriving, happy baby boy today. “As for myself, I am still healing, emotionally and physically,” said Lauterbach. (MaKenna Lauterbach)
“When you’re pregnant with a baby that’s nearly full term, your lungs already aren’t functioning at full capacity, and when you add a huge tumor on top of it, you run the risk of having respiratory collapse and cardiac arrest.”
The baby was not tolerating the contractions well and Lauterbach’s blood pressure was plummeting.
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The team performed an emergency cesarean section — and on Easter Sunday, a healthy baby boy, Colten, was born.
‘Blindsiding news’
After the delivery, it was time to address the tumor.
“The tumor was sitting on top of MaKenna’s heart and extended into the right lung, impacting all three lobes and the entire main trunk of the pulmonary artery,” said Kalvin Lung, M.D., a thoracic surgeon with the Northwestern Medicine Canning Thoracic Institute, in the release.
Doctors performed a biopsy and diagnosed Lauterbach with stage 3 melanoma.
The Lauterbach family lives on a farm in Washburn, Illinois. MaKenna Lauterbach first experienced severe coughing fits and shortness of breath when tending to the horses and goats. (MaKenna Lauterbach)
The doctors believe she may have had a melanoma on her skin at some point, and that “a cell or two escaped” and began growing inside her body.
“It was truly blindsiding news,” Lauterbach told Fox News Digital. “When I first got the diagnosis, I went through a roller coaster of emotions.”
“I was grieving the birth plan I had spent months preparing, while also dealing with the news of my unexpected diagnosis.”
After first feeling relief at having an answer, she said she felt some anger that her symptoms had been dismissed earlier. Then there was the fear of the cancer itself.
“Because of the tumor, the delivery happened so quickly. I was grieving the birth plan I had spent months preparing, while also dealing with the news of my unexpected diagnosis,” she said.
“My situation was serious, and while my clinical team was working on a plan to treat my cancer, it was comforting to know that the NICU nurses [at Northwestern] were taking such wonderful care of our son.”
Taking life-saving action
The team at Northwestern recommended that Lauterbach undergo three cycles of immunotherapy before surgery, which helped shrink her tumor by 30%.
Dr. Lung and Dr. Mehta removed Lauterbach’s entire right lung, parts of the main pulmonary artery and her lymph nodes.
The Lauterbach family is pictured with, left to right, Dr. Kalvin Lung, registered nurse Mary Schuessler and Dr. Lynn Yee. (Northwestern Medicine)
“The surgery was risky relative to other cancer surgeries due to the need for cardiopulmonary bypass, and the need to repair the main artery going to both lungs, but it was done under very safe conditions with well-proven techniques,” Dr. Lung told Fox News Digital.
“We were concerned that even with the extent of surgery, we would not be able to completely remove the tumor,” he went on.
If the tumor had grown just slightly more into the main artery going to the lungs, or if it had involved the heart, it would have been a different outcome.
But the surgery was a success, and Lauterbach’s latest scans showed no evidence of metastatic melanoma.
Colter Lauterbach is pictured with Santa ahead of his first Christmas. (MaKenna Lauterbach)
“Her outcome was very good,” Dr. Lung told Fox News Digital. “She has recovered from surgery almost entirely, and her main issue is shortness of breath, which is a consequence of only having one lung.”
“In terms of cancer prognosis, we expect it to be quite good, given that the entire tumor responded to the immunotherapy treatment she received.”
‘New normal’
Today, though he was born three weeks early, little Colter Lauterbach is a thriving, happy baby boy.
“As for myself, I am still healing, emotionally and physically,” said MaKenna Lauterbach. “My lung capacity is getting close to ‘the new normal’ for me and I’m finally starting to return to some sort of normal routine.”
“There are some days when the bad memories and the unknowns haunt my thoughts.”
Looking ahead, Lauterbach will continue immunotherapy treatments for one year, and the doctors will continue to monitor CT scans to ensure the cancer doesn’t come back.
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Her cancer is currently considered a “stable disease,” doctors say, which means no new tumors have appeared.
The new mother, who turned 27 in October, said she is looking forward to her son’s first Christmas on the farm.
MaKenna and Parker Lauterbach are pictured with their son, Colter, after he was born by emergency cesarean section. (MaKenna Lauterbach)
“Emotionally, I try my best not to let reality weigh on me, but there are some days when the bad memories and the unknowns haunt my thoughts,” she said.
“Colter and my wonderful husband, Parker, are what have given me the strength to make it through everything.”
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For other women, Lauterbach emphasized the importance of “knowing your body.”
She advised, “If you know something isn’t right, don’t take ‘I don’t know’ for an answer. Find someone who will take your concerns seriously and would rather do extra testing just in case, as opposed to missing something life-threatening.”
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A new injectable therapy is showing positive results in reducing melanoma throughout a five-year period.
The personalized mRNA cancer therapy, called intismeran autogene, combined with the cancer immunotherapy drug KEYTRUDA (pembrolizumab), is a collaboration between Merck and Moderna.
The results from the phase 2b KEYNOTE-942 study were presented at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago on May 27.
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After about a five-year follow-up, the combo drug was found to reduce the risk of melanoma recurrence or death by 49% compared to pembrolizumab alone.
The researchers analyzed data from 157 patients with high-risk stage 3 and 4 melanoma whose cancer had been removed via surgery. The participants were split into two groups — one received the combo therapy and the other only received pembrolizumab, according to a press release.
The therapy was found to reduce the risk of melanoma recurrence or death by 49% compared to pembrolizumab alone after a five-year follow-up. (iStock)
The findings revealed that the combination group saw benefits that were “sustained and durable over time.”
Intismeran autogene is designed using mutations identified in a patient’s own tumor, with the intention of teaching the immune system what the cancer looks like so that it can recognize and attack it.
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According to the researchers, intismeran is “well-tolerated” with a “manageable” safety profile.
The most commonly cited side effects of the personalized mRNA vaccine plus KEYTRUDA were fatigue, injection-site pain, chills, fever and headache. The researchers reported no new long-term safety concerns and no severe vaccine-related adverse events.
The combination therapy is currently being evaluated in a phase 3 study — the final confirmation stage.
Patients with late-stage melanoma have a “significant risk” of cancer recurrence, according to an expert. (iStock)
In a Merck press release from January, Kyle Holen, MD, Moderna’s senior vice president and head of development, oncology and therapeutics, noted that this data highlights the “potential of a prolonged benefit … in patients with resected high-risk melanoma.”
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“We continue to invest in our platform in oncology because of encouraging outcomes like these, which illustrate mRNA’s potential in cancer care,” he said.
Dr. Marjorie Green, senior vice president and head of oncology, global clinical development at Merck Research Laboratories, also commented that for many patients with stage 3 or 4 melanoma, there is a “significant risk of recurrence following surgery.”
Researchers confirmed that the combination therapy is currently being evaluated in a phase 3 study. (iStock)
“As such, demonstrating the longer-term potential of intismeran autogene and KEYTRUDA to reduce the risk of recurrence for certain patients with melanoma is a meaningful milestone,” she said.
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The company cited encouraging five-year follow-up data and pointed to upcoming late-stage INTerpath trial results with Moderna in several hard-to-treat cancers.
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An accidental lab discovery has opened the door to entirely new ways of preventing the flu.
While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells, SWNS reported.
By targeting the specific molecules the viruses rely on, scientists found that they could block them from entering new cells and halt their replication altogether.
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Researchers say these “fundamental insights” into seasonal influenza highlight a clear path toward developing better preventive medications.
“The hope is that fundamental, curiosity-based research like this helps to pave the way for novel strategies to treat and prevent influenza infections,” principal investigator Dr. Emily Bruce, from the University of Vermont’s Larner College of Medicine, said in the SWNS report.
While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells. (iStock)
While several flu strains cause illness, H1N1 and H3N2 influenza A viruses are the most common. However, current flu tests cannot differentiate between them, and clinical treatments are identical for both.
Although vaccines and antivirals are available, Bruce noted a “dire” need for better medications to stop the virus from spreading cell to xxcell.
“You don’t get sick when a virus is in one cell,” he noted. “You get sick because a virus replicates itself and goes into many more cells.”
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The study, which was published in The Journal of Virology, originally aimed to map how viral RNA segments are transported within cells to create new viral particles.
The team used H1N1 and H3N2 viruses isolated from the nasal passages of positive patients in 2022.
Clinical treatments remain identical for both primary strains of the flu virus. (iStock)
During the investigation, the team unexpectedly stumbled upon a cellular pathway that blocked the virus from entering lung cells, SWNS reported.
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The data revealed that when a specific human protein called Rab11B was depleted, H3N2 viruses failed to enter human lung cells. H1N1 viruses were completely unaffected.
Using reverse genetics, the team mapped this defect and uncovered a brand-new, H3N2-specific role for Rab11B during viral entry.
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This discovery challenged the scientific assumption that all flu viruses enter cells the same way.
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“Viruses are like pirates from different countries hijacking someone’s ship,” Bruce said. “Different viruses, like different types of pirates, use different methods to get onboard.”
This discovery challenged the scientific assumption that all flu viruses enter cells the same way. (iStock)
“We had previously thought that all flu viruses used the same way to get into a cell, but we discovered that this is not true,” she went on. “H1N1 and H3N2 need different proteins to get in, and if you get rid of the right protein, a specific virus can’t get in.”
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While these findings identify a critical cellular pathway for viral entry, the study was conducted using isolated cells, the researchers acknowledged.
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Further research is needed to determine whether blocking the protein is safe and effective within a live, complex human respiratory system.
Bruce and the team hope to conduct further research to determine whether this Rab11B-dependency is a fundamental property of H3N2, or if it’s a trait unique to currently circulating flu strains.
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Eating processed meat like ham, sausage and bacon may be linked to a higher risk of certain types of cancer, according to new research.
While health organizations have already confirmed that processed meat can contribute to colon cancer, this study looked closer at cancers in the upper digestive tract, where the link has historically been less clear.
To understand these connections, researchers from the European Prospective Investigation into Cancer and Nutrition (EPIC), one of the world’s largest long-term nutrition and cancer cohorts, tracked the health and diets of 450,112 people across Europe for an average of 14 years.
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The study group included 131,426 men and 318,686 women, according to the study’s press release.
During the follow-up period, 876 people developed stomach cancer and 215 people developed esophageal adenocarcinoma, which is cancer of the tube connecting the mouth to the stomach.
For female participants, eating both processed meat and white meat was linked to an increased risk of developing the disease. (iStock)
Researchers tracked where the stomach cancers grew, separating them into the upper part of the stomach near the throat and the lower part of the stomach.
The researchers also sorted the tumors into two categories based on how the cancer cells appeared under a microscope: intestinal, which forms more organized structures, and diffuse, in which the cells are more scattered throughout the tissue.
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After adjusting for other lifestyle factors, the researchers found that for every extra 30 grams of processed meat a person ate per day, their overall risk of stomach cancer went up by 9%. Eating that same extra 30 grams a day was also linked to a 13% higher risk of esophageal adenocarcinoma.
A standard single slice of regular deli-sliced ham or lunch meat averages around 28 grams, according to USDA data and nutritional tracking databases.
An extra 20 grams of white meat, such as chicken and turkey, was linked to a 12% higher risk of cancer in the main body of the stomach. (iStock)
An extra 20 grams of white meat, such as chicken or turkey, was linked to a 12% higher risk of cancer in the main body of the stomach, the researchers noted.
The study also revealed differences between men and women. For male participants, only processed meat showed a clear, statistically significant link to a higher risk of stomach cancer. For female participants, however, eating both processed meat and white meat was linked to an increased risk.
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These findings align with global health benchmarks, particularly those established by the World Health Organization’s International Agency for Research on Cancer.
The agency has long classified processed meat as a known human carcinogen, primarily due to its strong, well-documented links to colorectal cancer.
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However, health organizations have also consistently pointed to a potential, yet less definitive, relationship between these meats and cancers of the stomach.
Eating 30 grams of processed meat a day, or the equivalent to one slice of ham, was linked to a 13% higher risk of esophageal adenocarcinoma. (iStock)
Further scientific investigation is needed to confirm the findings and to account for other underlying risk factors, such as certain stomach infections, which could interact with dietary habits.
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A key limitation of the study is its reliance on self-reported diets, which can sometimes lead to inaccuracies in how participants recall their meat consumption over time, the researchers noted.
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The findings were published in the International Journal of Cancer.
Fox News Digital reached out to the researchers requesting comment.
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