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Shingles vaccine connected to ‘exciting’ health benefits in large study

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Shingles vaccine connected to ‘exciting’ health benefits in large study

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The shingles vaccine is intended to prevent shingles, a painful rash caused by the reactivation of the varicella-zoster virus, also known as herpes zoster — but a new study suggests that it could have major secondary benefits.

Researchers at Case Western Reserve University have identified a potential link between the shingles vaccine and a reduced risk of developing vascular dementia.

The vaccine has also been associated with a significant decreased risk of cardiovascular events and death in people 50 and older.

Researchers have identified a potential link between the shingles vaccine and a reduced risk of developing vascular dementia. (iStock)

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Experts presented the findings last week at the Georgia World Congress Center in Atlanta, the site of IDWEEK 2025, a joint annual meeting of the leading infectious disease professional societies in the U.S.

The study authors examined health records from 174,000 adults in the U.S. They followed participants who received the vaccination over a span of three months up to seven years.

DEMENTIA RISK NEARLY DOUBLES AMONG THOSE WITH COMMON SLEEP DISORDER, STUDY FINDS

Participants who received the shingles vaccine had about half the risk of developing vascular dementia.

They also had a 25% lower risk of heart attack or stroke, a 27% lower risk of blood clots and a 21% lower risk of death, according to a news release from the Infectious Diseases Society of America.

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Shingles is a red, blistery, painful rash caused by the reactivation of the virus that causes chicken pox.  (iStock)

“Our study findings show that the shingles vaccine may help lower those risks, especially in people already at higher risk for heart attack or stroke,” presenting author Ali Dehghani, a doctor of internal medicine at Case Western Reserve University’s School of Medicine in Cleveland, Ohio, said in the IDSA report.

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Shingles is a red, blistery, painful rash caused by the reactivation of the virus that causes chicken pox. The latent varicella zoster virus lies dormant in the body after a person has chicken pox. It can become activated in later years, causing shingles, health experts told Fox News Digital.

Participants who received the shingles vaccine had about half the risk of developing vascular dementia. (iStock)

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The condition can lead to cardiovascular and neurologic complications, previous studies have shown.

Shingles affects one out of three Americans, and more than 99% of those born before 1980 have had chicken pox, according to the Centers for Disease Control and Prevention.

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“Shingles is more than just a rash — it can raise the risk of serious problems for the heart and brain,” Dehghani said in the news release.

These latest findings build on past studies that indicate the vaccine may help protect individuals against shingles and related complications, according to infectious disease experts.

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“This very interesting study … supported prior evidence that the shingles vaccine may offer several benefits for general health, including against the development of dementia, in addition to preventing the very painful and common illness know as shingles,” Dr. Aaron Glatt, a spokesperson for the ISDA and a board-certified infectious disease physician at Mount Sinai South Nassau in Oceanside, New York, told Fox News Digital.

While more studies are needed, a doctor said, “It is very comforting to know that the shingles vaccine is certainly associated with overall significant health benefits beyond its intended purpose.” (iStock)

Although these findings are “very exciting and potentially clinically important,” Glatt — who was not involved in the study — noted that it’s not yet proven that these benefits are due to the shingles vaccine.

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There are a number of possible mechanisms that could contribute to this association, including decreased inflammation, the doctor pointed out.

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While more studies are needed, Glatt said, “It is very comforting to know that the shingles vaccine is certainly associated with overall significant health benefits beyond its intended purpose.”

The CDC recommends two doses of recombinant zoster vaccine (RZV) to prevent shingles and related complications in adults aged 50 years and older, as well as for adults aged 19 and older who are or will be immunodeficient or immunosuppressed.

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Dementia risk signals could lie in simple blood pressure readings, researchers say

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Dementia risk signals could lie in simple blood pressure readings, researchers say

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Simple measurements taken during routine blood pressure checks could predict dementia risk years before symptoms appear.

That’s according to new research presented this week at the American College of Cardiology’s Annual Scientific Session in Louisiana.

The findings draw on two studies led by researchers at Georgetown University, which suggest that monitoring how blood vessels age and stiffen over time can provide a window into future cognitive health.

LURKING DEMENTIA RISK EXPOSED BY BREAKTHROUGH TEST 25 YEARS BEFORE SYMPTOMS

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Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age, and half of U.S. adults have high blood pressure (hypertension).

Scientists believe that efforts to better address hypertension, a key contributor to heart disease and a risk factor for dementia, could affect both cardiac and brain health.

Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age. Meanwhile, half of U.S. adults have high blood pressure. (iStock)

“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health,” Dr. Newton Nyirenda, the study’s lead author and an epidemiologist at Georgetown University in Washington, said in a press release.

The research focused on two metrics, the pulse pressure-heart rate index and estimated pulse wave velocity. Both were calculated using data collected during standard doctor visits, such as heart rate, age and blood pressure.

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“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health.”

Researchers examined five years of data patterns for more than 8,500 people in the SPRINT trial, a large study of adults 50 years and older with hypertension. In the follow-up, 323 of the participants developed probable dementia.

HIDDEN BRAIN CONDITION MAY QUADRUPLE DEMENTIA RISK IN OLDER ADULTS, STUDY SUGGESTS

In one study, the team found the pulse pressure-heart rate index was a strong independent predictor of dementia risk in adults over 50. For participants under 65, every one-unit increase was associated with a 76% higher risk of developing dementia.

For participants under 65, an increase in the pulse pressure-heart rate index was associated with a 76% higher risk of developing dementia. (iStock)

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The second study found that adults with consistently elevated or rapidly increasing pulse wave velocity were more likely to develop dementia than those with stable velocity, even after accounting for factors like smoking, gender and cardiovascular history.

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“Our findings suggest that vascular aging patterns may provide meaningful insight into future dementia risk,” said Nyirenda. “This reinforces the idea that managing vascular health earlier in life may influence long-term brain health.”

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The team emphasized that clinicians should tailor risk assessments and treatment strategies to the individual.

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Further studies are needed to confirm these parameters and determine whether changing vascular aging trajectories reduces dementia risk. (iStock)

“You don’t want to wait until a patient starts manifesting cognitive decline before you act,” said senior study author Sula Mazimba, an associate professor at the University of Virginia.

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Researchers noted the study could not establish causation. Other limitations included the fact that participants already had hypertension and elevated cardiovascular risk, meaning the findings may not apply to people without those conditions.

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Further studies are needed to confirm these findings and to determine whether improving blood vessel health over time could reduce dementia risk.

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs


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What Is Zepbound? Weight-Loss Benefits, Costs and Dosage




















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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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A dangerous substance dubbed “gas station heroin” continues to alarm medical professionals, with more states making moves to restrict or ban tianeptine.

Fourteen states have officially classified the tricyclic antidepressant as a Schedule I controlled substance.

Connecticut is the latest state to crack down, officially banning the sale and use of the substance starting on Wednesday.

HEALTH OFFICIALS WARN OF DANGEROUS SUBSTANCE AVAILABLE IN STORES ACROSS THE NATION

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Tianeptine, which can produce euphoria in higher doses, can be more potent than morphine and addictive opioids, according to the U.S. Food and Drug Administration.

Some countries have taken steps to restrict how tianeptine is prescribed or dispensed, and have even revised the labels to warn people of its potential addictive qualities.

Tianeptine can be more potent than morphine and addictive opioids. (iStock)

Misuse of tianeptine can cause severe adverse health effects, including respiratory depression, severe sedation and death, according to the Drug Enforcement Administration.

Some companies market the drug as an aid for pain, anxiety and depression, or as a means of improving mental alertness in a pill, powder, salt or liquid form.

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The products are typically sold at convenience stores, gas stations, vape shops and online retailers, and go by names like Tianaa, ZaZa, Neptune’s Fix, Pegasus and TD Red.

Connecticut is the 15th state to classify tianeptine as a Schedule I controlled substance. (Markus Scholz/picture alliance via Getty Images)

Connecticut Lt. Gov. Susan Bysiewicz said in a press release that the schedule change is a necessary step to combat addiction.

“With false marketing that led consumers to believe these are safe products, and with candy-like flavor options, these substances posed a clear threat to those battling substance-use disorder and our youngest residents,” she added.

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The Nutmeg State also added Mitragyna speciosa (kratom), 7-hydroxymitragynine, Bromazolam, Flubromazolam, Nitazenes and Phenibut to the schedule classification.

Earlier this month, FDA Commissioner Martin Makary penned a letter sounding the alarm on what he called a “dangerous and growing health trend.”

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“I am very concerned,” Makary wrote. “I want the public to be especially aware of this dangerous product and the serious and continuing risk it poses to America’s youth.”

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New York-based Robert Schwaner, M.D., vice chair of system clinical affairs at Stony Brook Emergency Medicine, told Fox News Digital that the FDA has never approved tianeptine as a dietary supplement.

“As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.” (Dekalb County Sheriff’s Office)

“The euphoria at low doses is primarily due to increased serotonergic activity from its serotonin reuptake effects. With increasing doses, the mu-opioid receptor stimulation may become lethal,” said Schwaner. “As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.”

Schwaner said he believes the substance requires national regulation due to its addictive qualities. 

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“Acting at the same receptor as opioids, tianeptine has the potential for an individual to develop tolerance, subsequent dependence and withdrawal from its use,” he cautioned.

Fox News Digital reached out to the FDA for comment. 

Fox News Digital’s Greg Wehner and Melissa Rudy contributed to this report.

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