Science
1,200% jump in kratom-related calls to poison control centers in last decade, analysis shows
Over the last decade, poison control centers around the country have received tens of thousands of calls from consumers of kratom products reporting adverse and life-threatening health effects, with researchers saying reports in 2025 reached a new level. California’s poison center is reporting similar findings.
Last month, researchers analyzed information from the National Poison Data System and found that between 2015 and 2025, poison control centers across the nation received 14,449 calls related to kratom. More than 23% of those calls, or 3,434, were made last year, according to a published report in the Centers for Disease Control and Prevention. That represents a more than 1,200% increase from 2015, when only 258 calls were reported.
Officers gather illegally grown kratom plants in 2019 in Phang Nha province, Thailand. The country decriminalized the possession and sale of kratom in 2021.
(Associated Press)
Kratom is derived from the leaves of Mitragyna speciosa, a tree native to Southeast Asia. It has a long history of being used for chronic pain or to boost energy and in the U.S., research points to Americans also using it to alleviate anxiety. In low doses, kratom appears to act as a stimulant but in high doses, it can have effects more like opioids.
But in the last few years, a synthetic form of kratom refined for its psychoactive compound, 7-hydroxymitragynine or 7-OH, has entered the market that is highly concentrated and not clearly labeled, leading to confusion and problems for consumers. The synthetic form gaining momentum in the market is sparking concern among public health officials because of its ability to bind to opioid receptors in the body, causing it to have a higher potential for abuse.
Los Angeles County leaders, meanwhile, have grappled with differentiating the two and regulating the products that come in the form of powder, capsules and drinks and have been linked to six county deaths. Sales of kratom and 7-OH products were banned in the county in November.
In reviewing the data, which did not differentiate whether callers had consumed natural or synthetic kratom, researchers set out to understand the effect of what they believe is a “rapidly evolving kratom market,” and highlight the role poison centers can play as an early warning surveillance system to detect new trends.
National Poison Data System findings
The data showed that over the last 10 years, 62% of the kratom-related calls to poison control centers were from people who said they consumed the drug by itself, and the other 38% were from people who combined it with another substance or substances.
Those who consumed kratom with another substance combined it most frequently with one or a combination of the following: alcohol, opioids, benzodiazepines (like Xanax or Valium), cannabis and cannabinoids, stimulants and antidepressants.
The data also broke down hospitalizations related to kratom — adults who took it alone or in combination and experienced “adverse” health effects; and adults who took it alone or in combination and experienced more serious “moderate” or “major” health effects, including death.
Kratom powder products are displayed in a smoke shop in Los Angeles in 2024.
(Michael Blackshire/Los Angeles Times)
Hospitalizations for adults who had consumed kratom alone and experienced adverse effects increased from 43 in 2015 to 538 in 2025. For those who took it in combination and were hospitalized with an adverse health effect, the total jumped from 40 in 2015 to 549 last year.
The numbers were even higher for hospitalizations where the health effects were more serious or fatal.
In 2015, there were 76 reports of people being hospitalized after taking kratom alone and experiencing a serious health effect or dying. By last year, that number had climbed to 919. The reports of serious health effects, including death, for those who took kratom in combination with another substance grew from 51 in 2015 to 725 last year.
The research does not break down kratom-related deaths by year but states that there were 233 deaths over the 10-year study period, or just over 3% of all 7,287 serious medical outcomes. Of the total number of kratom-related deaths, 184 cases involved the consumption of multiple substances.
What California’s poison control system found in its state data
The California Poison Control System is currently reviewing its data concerning kratom-related calls but an initial analysis shows parallels to the national report, said Rais Vohra, medical director of the state poison control system.
“We have about 10% of the national population and about 10% of the national call volume with poison control,” Vohra said. “And so, not surprisingly, we were able to identify over 900 cases of calls related to kratom in that same period.”
Local researchers are still deciphering the state data but they too have found that kratom-related calls are climbing.
“It’s accelerating, which I think is one of the main points of the [published] report,” Vohra said.
A majority of calls received by poison control come from healthcare facilities where “presumably someone has a problem … severe enough to warrant calling 911 or going to the emergency room, and that’s when our agency gets involved,” Vohra said.
Kait Brown, clinical managing director for America’s Poison Control Centers, said the fact that kratom and 7-OH are federally unregulated products sold online, in gas stations and smoke shops gives people across the country easy access.
And while kratom enthusiasts maintain that it has been used in its natural form for hundreds of years, “there are new formulations that are a little bit different than how people have used it, at least historically,” said William Eggleston, a pharmacist and the assistant clinical director of the Upstate New York Poison Center in Syracuse.
People are no longer consuming kratom only as a powder or capsule but also in the form of an energy shot or extract; it’s similar for synthetic, more concentrated 7-OH products.
When regional poison centers compare their findings and experiences with the analysis of calls in the National Poison Data System, Eggleston said, “undeniably there is an increase in calls related to kratom.”
“But when you put it in the bigger perspective of all the calls … this is still a very small percentage of what we’re dealing with on a day to day basis,” he said.
Science
A Physicist Who Thinks in Poetry from the Cosmic Edge
Much of the praise for Chanda Prescod-Weinstein’s debut book in 2021, “The Disordered Cosmos: A Journey Into Dark Matter, Spacetime, and Dreams Deferred,” lauded the way she used personal experiences in physics to discuss the social and political inequities that exist alongside scientific breakthroughs.
“It contains the narrative of dreams deferred,” Dr. Prescod-Weinstein, a physicist at the University of New Hampshire, explained in April at a bookstore in Chicago. But its very existence, she said, also “represented a dream deferred, because that was not the dream of what my first book was going to be.”
Her second book reclaims that dream. Released on April 7, “The Edge of Space-Time: Particles, Poetry, and the Cosmic Dream Boogie” is less pain and more play, a homage to the big questions that made Dr. Prescod-Weinstein want to become a physicist in the first place. She begins the book by asserting that it is humanity’s duty to uncover and share the story of our universe. Her latest offering toward that duty is a journey through physics that is tightly bound to her own cultural roots.
In the midst of a multicity book tour, Dr. Prescod-Weinstein spoke with The New York Times about guiding readers through the cosmos from her own point of view and about some of the art, poetry and literature she drew on to shape that journey. This conversation has been edited for brevity and clarity.
Why include so many references to poetry in a book about physics?
I knew poetry before I knew physics. It was part of my upbringing. I loved A.A. Milne’s “Now We Are Six” and Edward Lear’s “Nonsense Limericks.” Both of my books draw their subtitles from Langston Hughes’s “Montage of a Dream Deferred.”
Adrienne Rich’s poem “The Burning of Paper Instead of Children” became a guiding light for how my work would move in the world. It also opened up for me that I need language. That’s true among physicists. Even an equation is a sentence; even an equation is telling a story.
As physicists, we’re always working in language to connect what we learn with what we know. Poetry is one of the first places that my brain goes to draw those links. Language, as it moves in my brain, is often in Hughes and Rich and Shakespeare. Those are the lines that flicker up for me.
What if we got away from the argument that doing cosmology and particle physics is practical or materially valuable? Then we have to accept that we’re like the poets. What we do is important culturally in the same way poetry is. A piece of this book is me saying there is value in banding with the poets, and fighting for the value of being curious and trying to articulate the world with whatever tools are available to us. Not for the purposes of selling something, but for the purpose of fulfilling our humanity.
Another theme throughout the book is the story of Lewis Carroll’s Alice and her adventures in Wonderland.
Being a science adviser on future installments in The Legendborn Cycle, a fantasy series written by Tracy Deonn, is one reason Alice is in my book. It has allowed me to be open to the playful side that physics, as a Black queer person, can take from you. I wanted the book to be whimsical, because that’s who I was when I first arrived in physics, and that’s who I want to be when I die.
Part of the call of quantum physics is to change what our sense and sensibility are. When you look at the world through this framework — like the idea that particles have spin but don’t really spin — it sounds like nonsense. Except that’s literally how the universe works. Physics is our “through the looking glass.” It’s real.
Your first chapter invites readers to reflect on the metaphors used to describe the universe, like the “fabric” of space-time or electromagnetic “fields.” Why open in this way?
A lot of books about quantum physics start with its history. I wanted as much as possible not to just do that. I had actually planned to start it with the Stern-Gerlach experiment of 1922. But then I read an essay by the poet Natasha Trethewey about abiding metaphors and started to ask myself what the abiding metaphors of my physics training were.
We don’t ever take time in our classes to ask, “What do we mean when we say ‘space’? What do we mean when we say ‘space-time’?” There are these metaphysical questions that I often told myself were for the philosophers. This book was me letting myself think of them as physics.
One metaphor you invoke is the “edge” — not only the edge of the universe and of scientists’ understanding, but also existing at the edge of certain identities.
In “Disordered Cosmos,” I talked a lot about being at the margin and looking toward the center. With “The Edge of Space-Time,” I’m choosing to make the margin the center of the story. Part of that was me fully embracing what makes me the physicist I am. I’m an L.A. Dodgers fan. I love “Alice in Wonderland.” I love “Star Trek.” There’s lots of all of that in the book.
Picking a metaphor is a culturally situated decision. I wrote a line that says black holes are the best laid edges in the universe. I did, at some point, think that only some people were going to get this. But for people who don’t understand the reference to Black hairstyles, the sentence is still legible. And for those who do, it will feel like we just had an in-group moment. Anyone who thinks about laying their edges deserves to have an in-group moment in a physics book. Because we are physics, too.
Black students are often told that if you want to be a physicist, then you will make yourself as close to such-and-such mold as possible. At a young age, we have this understanding that whiteness and science are associated with each other, but we are also witnessing in ourselves that this can’t be entirely correct. There’s this narration of, “Well, sure, you can be Black in physics, but that means you have to acclimate to the ‘in physics’ part, and never that physics has to acclimate to the Black part.”
I use the example of rapper Big K.R.I.T.’s song “My Sub Pt. 3 (Big Bang),” in which someone tries to wire up subwoofers in his car but fries the wires because he doesn’t ground them properly. I don’t know if Big K.R.I.T. would think of this as a science story, but I think we should learn to read it as one. Not to contain it in science, but to say it overlaps there. This can be a rap song. It can be about the cultural significance of subwoofers and the Big Bang as a metaphor for the beat. And it can also be about cosmology and about how everybody who wires up cars or does this kind of work is a scientist, too.
How do you want readers to approach this book?
There is this feeling that you’re supposed to read a book like this and walk away an expert. That’s actually not the point of this book at all. The point is to wander through physics. Even if math terrifies you, you are entitled to spend some time with it.
And so here, I have made you a book with a bunch of tidbits on the oddities of the universe. The universe is stranger and more queer and more wonderful and more full of possibility than whatever limitations you might be experiencing right now. Physics challenges what we are told are social norms. For example, non-trinary neutrinos are fundamental to our standard model of physics.
“Non-trinary,” as in they shift between three different forms.
Non-trinary is natural. It’s such a challenge to the current anti-trans rhetoric that says people can only ever be one thing.
I don’t need my book to be the most important thing that someone reads. But I want it to be a source of hope. If it reminds you that, as my mom says, the universe is bigger than the bad things that are happening to us, then that’s all you need to remember. I’m good with that.
Science
Footage shows Central Valley dairy workers kicking young calves, pulling them with pliers
In late February, animal rights activists flew a drone over a calf ranch in the Central Valley and watched as workers kicked and punched the animals.
For the record:
7:15 p.m. May 12, 2026This article has been updated to reflect that no calves from Agresti Calf Ranch have ever gone on to be used for Clover Sonoma milk supplies, and the calf ranch opened only in 2025. In additional comments, Clover Sonoma also said in the future, no animals from Agresti Calf Ranch will be part of its supply.
Footage reviewed by The Times shows a worker pulling a calf by the nose with pliers.
It shows two workers removing the budding horns of a calf with a hot iron. While one held the frightened animal’s head, the other — wearing a sweatshirt with an image of the Virgin Mary — applied the iron to a horn. After a puff of smoke, the calf fell to its side, appearing motionless.
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Both male and female calves produce horns. To prevent injury to the animals and their handlers, these are commonly removed. Humane guidelines require anesthesia.
The footage was collected by the group Direct Action Everywhere, known for tactics including releasing beagles from medical breeding facilities and abused calves from farms. It was shot at the Agresti Calf Ranch in Ceres, near Modesto, which is certified by the American Humane Society for its ethical treatment of animals. The workers could not be reached for comment. One was subsequently terminated, the Humane Society said.
The Agresti Calf Ranch opened in 2025 and is operated by the owners of Double D Dairy, just up the road. Double D Dairy owns more than 10,000 cows across several operations.
The owner of Double D, Dominic Assali, declined to answer questions in person. A phone number for the dairy online is disconnected. In response to an email to his personal account, Assali said, “Animal welfare and safety are incredibly important to us, and we have a zero-tolerance policy for any mistreatment.
“We’ll always take immediate, thorough action to address any operational issues, as we have in this instance,” the email said.
The American Humane Society is a 150-year-old nonprofit focused on animal welfare. Among other things, it certifies animal safety on farms as well as on movie sets. In a statement, it said only 10% of animals raised on farms in the U.S. are certified as humanely treated.
Assali is the grandson of the farm’s founders, Harold and Marlene Agresti. He is a board member of Western United Dairies, the largest dairy trade group in California.
The mistreatment captured on video has also created a headache for a prominent California sustainable milk brand, Clover Sonoma, based in Sonoma County.
It gets 10% to 15% of its milk from Double D, and Assali and his family are featured on Clover Sonoma’s website. No calves from Agresti Calf Ranch have ever gone on to be used in Clover Sonoma milk supplies, the company said in a statement. It’s unclear whether the abused calves were being raised for beef or dairy.
A Clover Sonoma sign hung outside the main dairy complex on a recent visit.
Clover Sonoma markets its milk, yogurt and cheese products as humanely sourced and environmentally sound. It was the first dairy company to receive a cruelty-free certification from the American Humane Society in 2000. The website also features a “Our Promise” page, which states the company demands “the humane treatment of animals.”
“We were deeply concerned by the reported mistreatment of some cows captured on video at Agresti Calf Ranch during a separate cow operation,” the company said in an email.
“The rough handling shown at Agresti Calf Ranch is contrary and inconsistent with the humane practices we have fostered for decades and which we demand of all our suppliers.”
Clover Sonoma said it suspended business with Double D as soon as it became aware of the incidents and began “a rigorous audit,” which just ended.
“Clover and the American Humane Society have concluded that the mistreatment was an isolated issue, not systemic or reflective of Agresti Calf Ranch’s personnel. Corrections have been made, including the termination of the employee in the video. As such, we are comfortable reinstating the milk from Double D Dairy.”
After this story published, Clover went further and said a condition of Double D’s reinstatement will be that no animals from Agresti Calf Ranch will be part of Clover’s dairy supply.
A statement from the Humane Society said Clover Sonoma is working with Double D to strengthen its whistleblower policy and training, and has “reiterated its commitment to ongoing independent, third-party audits,” with both announced and unannounced visits.
Clover Sonoma mainly buys and processes milk from dairies in verdant Sonoma County, as the company’s marketing suggests. Double D Dairy is one of its few suppliers in the Central Valley, which is associated more with industrial-scale agriculture.
On a recent weekday, the calf ranch and dairy farm were visible from a public road. Holstein calves, a popular dairy breed, could be seen in cages through small trees in front of the enclosures. The sound of mooing and a pressure washer could be heard. The smell of manure and dirt wafted in the humid air.
Most dairy companies remove calves from their mothers after birth, raising them separately so they don’t take the mother’s commercially valuable milk. Some dairy farms send calves out to third-party calf ranches for rearing. Others raise them on-site. Female calves are typically raised to become milk cows. Male calves are sent away to become beef or other meat-based products, such as pet food.
A 2025 State Water Board document shows the farm houses an average of 700 calves at any one time, with a maximum 1,400.
The Direct Action Everywhere activists were recently on a public road near Double D’s main farm, flying a drone over the property. Within 30 minutes of their arrival, seven Stanislaus County sheriff’s vehicles arrived and surrounded the activists.
A heavily armed officer asked to see the drone pilot’s Federal Aviation Administration license, which he provided. After confirming it was valid, a sheriff’s deputy — one of nine at the scene — told the activists they could remain on the road but could not trespass.
Asked about the heavy response, a deputy said there had been several recent violent incidents from animal rights groups at the site, and mentioned the groups had sent in “busloads” of activists.
The Times reached out to the Sheriff’s Office to get more details about those events but did not get a response.
Temple Grandin, author and professor of livestock medicine at Colorado State University, said that punching and kicking livestock is considered abusive.
An expert in livestock welfare, she said that handlers can tap, push and nudge animals. But if the level of force goes beyond what could bend the side of a cardboard box, “it’s abuse. Period.”
She said the calves’ reaction to the hot iron indicates that pain medication, such as lidocaine, was not applied before the procedure. Double D did not respond to a question about whether medication was given before the procedure.
A pickup truck rolls by the barns at Agresti Calf Ranch at sunrise in Ceres.
(Tomas Ovalle/For The Times)
Science
A Taxidermist Gives Dead Animals a New Life
At 11, Tim Bovard undertook his first taxidermy experiment on a piece of roadkill. He had found an unlucky skunk and improvised its reanimation using an instruction book, much to the alarm of his friends’ parents.
His own parents were unfazed — his father and grandfather were both scientists and outdoorsmen — and soon it was known in their suburban community of Claremont, Calif., that, as Bovard recently recounted: “Dr. Bovard’s son was an animal nut. So when they found the abandoned birds, owls, hawks, kestrels, crows, blue jays, scrub jays, they brought them to me, and I raised them.”
By the time he was a teenager, he was sewing his own clothes, learning to tan leather and taking backpacking trips in the Sierras with his dogs while wearing a full buckskin suit of his own creation. He began apprenticing with a local taxidermist in high school, and then chose to work for him full time through college.
Bovard was always set on his life path, though when he visited friends at college parties, he asked them to stop mentioning what he did instead of going to class, noticing that it gave some people the creeps.
Bovard, still exuberant and energetic at 72, is the last full-time taxidermist at any museum in the United States. He still lives in Claremont, now with his wife, two dogs and “10 and a half cats” (the “half” cat lives mostly outdoors) and wakes most days at 4:30 a.m. to commute to the Natural History Museum of Los Angeles County, where he has worked since 1984. He is responsible for maintaining animal mounts the museum has kept in its collection for more than a century, reworking dioramas that could look more true to life and designing new exhibits.
In past generations, museums dispatched hunting expeditions to acquire their animal collections, but Bovard works only with donations from zoos or offerings from private collections. As when he was a child, roadkill is another option.
Once the skin is on and the glue is dry, he sews the pelt together, hiding his seams.
“Mammal stitching has to be pretty tight,” he said, especially for lions or zebras. “Now, a bear with long hair? It doesn’t matter so much. For birds, feathers cover it all.”
The care and keeping of these forms is a responsibility he takes both seriously and joyfully. Frequently, he skips his commute entirely and sleeps in his office, rolling out a blanket between filing cabinets that carry the records of every animal in the museum’s 111-year-old collection and the “fleshing wheel” he uses to gently remove tissue from hides.
“It wouldn’t be for everybody,” he said with a smile. “But I am known to be slightly different. That’s putting it sort of mildly.”
In fact, he has slept at work for weeks at a time, like when he was revamping the museum’s lion diorama and wanted to adjust furry skin folds and feline facial expressions every few hours during the night as the glue set.
Unlike many taxidermists, Bovard is responsible not only for the animals on display in the museum but also for very element of the dioramas, including every tree, leaf, twig, flower, dusting of snow and body of water. He’s made hundreds of thousands of leaves through a method called vacuum forming — a manufacturing technique where plastic is heated and then shaped around a mold using suction — using leaf molds he created himself from plant matter he harvested on research trips.
To do this exacting work, he has amassed an encyclopedic knowledge of the natural world. He knows, for example, that one key to designing a lifelike raptor is the hooding over the eyes. But he also knows the posture that raptor would take sitting on a tree branch, what kind of tree it would be sitting in, the patterns in which it would have preened its feathers, what kind of prey it might be looking for and how its presence would most likely affect the behavior of every other animal in its radius.
For a restaging of a lion family, he wanted two lionesses to be nuzzling foreheads, the standard greeting in big cats, to capture their sociality. He wanted to create more of a sense of dynamic movement in the scene of jaguars perched atop a box canyon in Sonora, Mexico, for example, by adding some small mammal prey, like javelinas, leaping away from the cats.
“It’s all about directing the eye,” he said, pointing toward the far corner of the painted background.
And then there are all the routine tasks, the things he’ll never stop doing, at least not until he retires, like dusting the museum’s pride of lions, vacuuming elephant ears and polishing all the glass eyes.
When asked about whether retirement is on the horizon, he laughed. He was still sleeping on his office floor as recently as New Years. There’s an orangutan he wants to mount this year, and tens of thousands more leaves to make. “No plans to retire.”
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