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Pittsburgh doctor hopes FDA-approved colon cancer blood tests boosts screening rates

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Pittsburgh doctor hopes FDA-approved colon cancer blood tests boosts screening rates


PITTSBURGH (KDKA) — A simple blood test to screen for colorectal cancer was approved by the U.S. Food and Drug Administration.

According to the American Cancer Society, 53,000 people will die of colorectal cancer this year and less than 60 percent follow screening guidelines. Doctors are hoping the newly approved screening tool will help change that.

“I’m very happy that we have an additional tool in our toolbox to help people get screened for colon cancer,” said Dr. James McCormick, chief of colon and rectal surgery at Allegheny Health Network.

Dr. McCormick is excited about the FDA-approved first-of-its-kind blood test. It’s meant for people 45 and older with an average risk for the disease.

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“You just get your blood drawn. What they’re doing is looking in the blood for circulating tumor DNA. So, DNA that the tumor will have released into the blood, and it would be able to detect that,” Dr. McCormick said.

In Guardant Health’s clinical trials, the blood test was 83 percent accurate in detecting cancer that’s already formed.

“That’s someone who’s already has a cancer. For the precancer solutions, unfortunately, it’s down in the 13 to 20% range that it can pick that up. So, it’s not going to pick up those polyps before they become cancer,” he said.

The Shield test is not a replacement for colonoscopies. Any positive blood test result would then require a colonoscopy.

“It’s different from a colonoscopy, which is the traditional screening test that we offer people, where we can take precancerous tumors at the time of the colonoscopy and remove them before they can become cancerous tumors. That’s still the best screening test, and really the only test that you should have if you have any symptoms at any age,” Dr. McCormick said.

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McCormick reiterated that people who get symptoms at any age should get screened and that everyone should be screened for colon cancer at age 45. He said despite efforts to spread the word, 20 or 25 percent of people never get screened.

He hopes the blood test will help boost the rate of screenings and save more lives.

“If there’s a reason that they’re not getting screened that is solved by the Shield test, then we’ll take it. We’ll get them in that way,” Dr. McCormick said.

This approval comes at a time when more people have been developing colon cancer at younger ages.

“We’re even seeing patients in their 20s and 30s with colon cancer, even with no family history. And we have no idea why or who is going to be affected by this,” Dr. McCormick said.

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He said never to ignore symptoms. If something is different with your bowel, fight for yourself and make sure you get the test you need.

“Anytime there’s bleeding, there’s abdominal pain, anytime there’s a change in the way your bowels work that persists more than just a few weeks, definitely call your doctor and insist upon getting a colonoscopy,” Dr. McCormick said.

The Shield test has been used by doctors for high-risk surveillance after treatment. A stool test is another screening tool that’s available.

Dr. McCormick said if a blood test and a stool test are negative, those would probably be repeated every three years. Negative colonoscopies only need to be done every 10 years.

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Pirates Winning Streak Ends With Loss to Cardinals

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Pirates Winning Streak Ends With Loss to Cardinals


PITTSBURGH — The Pittsburgh Pirates have had a strong showing so far in the Grapefruit League, but suffered a surprising defeat.

The Pirates lost 3-2 to the St. Louis Cardinals at LECOM Park in Bradenton, Fla., taking just their third defeat in Spring Training so far, dropping to 9-3 in the Grapefruit League.

Pittsburgh saw their five-game winning streak come to an end, but they are still level with the New York Yankees at the top of the Grapefruit League standings.

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This game also came after the first off day for the Pirates on March 4 and a 7-1 win over Team Colombia in an exhibition at LECOM Park on March 3.

How the Pirates Fell to the Cardinals

Pirates right-handed pitcher Mitch Keller made his third start in the Grapefruit League and threw three scoreless innings, before giving up a solo home run to Cardinals third baseman Nolan Gorman on a slider down in the zone, putting the road team up 1-0 in the top of the fourth inning.

That represented the first run that Keller gave up all Spring Training and Pirates left-handed relief pitcher Derek Diamond came in for him after he gave up a single to Cardinals right fielder Jordan Walker.

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Keller has just a 1.23 ERA over 7.1 innings for the Pirates in the Grapefruit League, a good start for the veteran on the starting rotation.

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St. Louis loaded the bases against Pirates left-handed relief pitcher Evan Sisk in the top of the fifth inning with three walks, but Sisk struckout top prospect in shortstop JJ Wetherholt and forced Gorman into a double play to keep it a one-run game.

Sep 11, 2025; Baltimore, Maryland, USA; Pittsburgh Pirates pitcher Evan Sisk (51) delivers a pitch during the eighth inning against the Baltimore Orioles at Oriole Park at Camden Yards. Mandatory Credit: James A. Pittman-Imagn Images | James A. Pittman-Imagn Images
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Pirates right-handed relief pitcher Chris Devenski gave up a run in the top of the sixth inning, as he walked second baseman Ramón Urías, who stole second base, then gave up a single to catcher Pedro Pagés, doubling the Cardinals’ lead at 2-0.

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The Pirates tied the game up at 2-2 in the bottom of the sixth inning, as shortstop Alika Williams hit a two-run home run off of Cardinals left-handed pitcher Quinn Mathews.

Pirates right-handed relief pitcher Cam Sanders gave up the go-ahead run in the top of the eighth inning, hitting leadoff batter Joshua Baez with a pitch and then giving up a single to pinch-hitter Jimmy Crooks to make it 3-2.

Right fielder Ryan O’Hearn had a strong showing for the Pirates in the loss to the Cardinals with two hits in two at-bats. He is now slashing .462/.563/.769 for an OPS of 1.332 in six Grapefruit League games.

Outfielder Jhostynxon Garcia had a hit off the bench for the Pirates, as he is now slashing .533/.611/.733 for an OPS of 1.344 in seven games.

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Make sure to visit Pirates OnSI for the latest news, updates, interviews and insight on the Pittsburgh Pirates!



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As his polarizing Pitt career winds down, a banged-up Cam Corhen has saved his best for last

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As his polarizing Pitt career winds down, a banged-up Cam Corhen has saved his best for last






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Can Pittsburgh Handle an NFL Draft Crowd?

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Can Pittsburgh Handle an NFL Draft Crowd?


Along with the best football prospects the season has to offer, the NFL Draft promises to bring hundreds of thousands of visitors to Pittsburgh from April 23 to 25.

If the turnout approaches that of Detroit in 2023, those descending on the North Shore and Downtown could reach 700,000 over the three days. For reference, that’s more than 10 times Acrisure Stadium’s 68,400 seats, and more than double the city’s roughly 308,000 residents.

Where will they stay? How will they get around?


Event planners at VisitPittsburgh say the city is up to the task.

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“They picked us out of several cities because we have the infrastructure,” said Perry Ivery, general manager of the Oaklander Hotel and board chair of VisitPittsburgh.

Last year, Wisconsin’s Green Bay comfortably accommodated a unique visitor count three times its 106,000 population, according to residents and local leaders.

Rooms Enough?

Ivery said there are some 26,000 hotel rooms across the Pittsburgh Metropolitan Statistical Area, the bulk of which are concentrated in and around Downtown.

Even if each room holds two to four people, the total still appears to fall short. But Ivery said many attendees will be locals, whether from Pittsburgh, surrounding counties or neighboring states within a day’s drive.

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Plus, a high proportion of out-of-town guests could have Pittsburgh roots and a free bed to claim in a family home, he added.

There are also around 3,500 units available for short-term rental in and around Pittsburgh through platforms like Airbnb and VRBO.

“We’re all working together to make sure everybody has a great hospitality experience in the City of Pittsburgh,” Ivery said.

Infrastructure from roads to parking, and bus and light rail routes, will also feel the strain.

Strain on the Train?

Pittsburgh Regional Transit normally services around 100,000 riders on an average weekday, across its entire network. Spokesperson Adam Brandolph said the agency is prepared for the transit demands of what’s expected to be the biggest event the city has hosted.

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“We’re confident that we’ll be able to meet the needs of visitors to the draft as well as daily riders,” he said, noting “no major closures or detours” are planned for the event other than the University Line project, which may see less construction during that week.

Brandolph said the agency is finalizing plans and intends to make more information public soon.

A spokesperson for VisitPittsburgh said a local committee is working with a range of stakeholders including transportation agencies, engineering partners and local government “to deliver a coordinated and comprehensive plan for the region.”

“This includes collaboration with public transit agencies on adjusted service plans, clearly marked detour routes, designated rideshare zones and proactive communication with residents, businesses and commuters,” said Alex Kenzakoski, communications director for VisitPittsburgh.

“Our shared goal is to minimize disruption, keep the region moving and make travel as predictable and seamless as possible for both fans and locals.”

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Kenzakoski said details on road closures, transit adjustments and travel guidance will be made known ahead of the draft, and encouraged fans to download the NFL OnePass app for transportation information and updates.

Ivery said a successful draft week execution could line Pittsburgh up for future hosting prospects.

“There’re going to be folks that come in that have never been to Pittsburgh … This is a case to showcase our town, and our hotels,” he said.

“We’re friendly, we have grit, we’re very excited to showcase that we can do large-scale activities.”

This story first appeared in Pittsburgh’s Public Source. Read the original here.

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