Health
History Isn’t Entirely Repeating Itself in Covid’s Aftermath
Five years after Covid-19 shut down activities all over the world, medical historians sometimes struggle to place the pandemic in context.
What, they are asking, should this ongoing viral threat be compared with?
Is Covid like the 1918 flu, terrifying when it was raging but soon relegated to the status of a long-ago nightmare?
Is it like polio, vanquished but leaving in its wake an injured but mostly unseen group of people who suffer long-term health consequences?
Or is it unique in the way it has spawned a widespread rejection of public health advice and science itself, attitudes that some fear may come to haunt the nation when the next major illness arises?
Some historians say it is all of the above, which makes Covid stand out in the annals of pandemics.
In many ways, historians say, the Covid pandemic — which the World Health Organization declared on March 11, 2020 — reminds them of the 1918 flu. Both were terrifying, killing substantial percentages of the population, unlike, say, polio or Ebola or H.I.V., terrible as those illnesses were.
The 1918 flu killed 675,000 people out of a U.S. population of 103 million, or 65 out of every 10,000. Covid has so far killed about 1,135,000 Americans out of a population of 331.5 million, or 34 out of every 10,000.
Both pandemics dominated the news every day while they raged. And both were relegated to the back of most people’s minds as the numbers of infections and deaths fell.
J. Alexander Navarro, a medical historian at the University of Michigan, said that in the fall of 1918, when the nation was in the throes of the deadliest wave of the 1918 flu, “newspapers were chock-full of stories about influenza, detailing daily case tallies, death tolls, edicts and recommendations issued by officials.”
During the next year, the virus receded. And so did the nation’s attention.
There were no memorials for flu victims, no annual days of remembrance.
“The nation simply moved on,” Dr. Navarro said.
Much the same thing happened with Covid, historians say, although it took longer for the virus’s harshest effects to recede.
Most people live as though the threat is gone, with deaths a tiny fraction of what they once were.
In the week of Feb. 15, 273 Americans died of Covid. In the last week of 2021, 10,476 Americans died from Covid.
Interest in the Covid vaccine has plummeted, too. Now just “a measly 23 percent of adults” have gotten the updated vaccine, Dr. Navarro noted.
Remnants of Covid remain — lasting financial effects, lags in educational achievement, casual dress, Zoom meetings, a desire to work from home. But few think of Covid as they go about their daily lives.
Dora Vargha, a medical historian at the University of Exeter, noted that there had been no ongoing widespread effort to memorialize Covid deaths. Instead, with Covid, “people disappeared into hospitals and never came out.”
Now it is only their friends and families who remember.
Dr. Vargha called that response understandable. People, she said, do not want to be “dragged back” into memories of those Covid years.
But some, like those suffering from long Covid, can’t forget. In that sense, she sees parallels with other pandemics that, unlike the 1918 flu, left a swath of people who were permanently affected.
People who contracted paralytic polio in the 1950s described themselves to Dr. Vargha as “the dinosaurs,” reminders of the time before the vaccine, when the virus was killing or paralyzing children.
Every pandemic has its dinosaurs, she said. They are the Zika babies living with microcephaly. They are the people, often at the margins of society, who develop AIDS.They are the people who contract tuberculosis.
But despite the pleas from those who cannot forget Covid and who seek more research, more empathy, more attention, the more pervasive attitude is, “We don’t need to care anymore,” said Mary Fissell, a historian at Johns Hopkins University.
That sounds so callous, and yet, said Dr. Barron Lerner, a historian at NYU Langone Health, in the world of public health “there are always people who are left behind — damaged or still at risk.”
“It’s hurtful” for people to be shunted aside, Dr. Lerner said. “Their lives are altered. The attention you feel their situation warrants is downplayed.”
But, he added, “on a realistic basis, there are any number of things to study.” Resources are limited, he noted, adding, “it can make sense to move on.”
One aspect of the Covid pandemic, though, is still with the nation, and seems to be part of a new reality: It has markedly changed attitudes toward public health.
Kyle Harper, a historian at the University of Oklahoma, said he would give the biomedical response to Covid an A-plus. “The rollout of vaccines was incredible,” he said.
But, he said, “I would give the social response a C-minus.”
Dr. Lerner had the same thought.
Few medical experts, he said, expected so much resistance to measures like masks, quarantines, social distancing and — when they became available — vaccines and vaccine mandates.
With Covid, he said, “compared to other pandemics, the amount of pushback to standard public health practices was remarkable.”
“That sets Covid apart,” he said. Public health measures that had worked in the past were rejected.
Some of the pushback was reasonable, he said, like objections to wearing masks outdoors. But the spurning of public health measures was widespread and politicized.
Dr. Navarro agreed and said the contrast with 1918 was striking.
“In 1918, there was an abiding respect for science and medicine that seems lacking today,” he said. There were pockets of resistance to measures like masking and avoiding large groups. But for the most part, he said, people complied with public health advice. And compliance was divorced from politics.
World War I also played a role in the messaging, Dr. Navarro said, which may have bolstered adherence.
“Public health orders and recommendations often purposely used the same language that was used to drum up support for the war effort,” Dr. Navarro said. The authorities, for example, asked people “to cover their coughs and sneezes so as not to gas their fellow citizens as the doughboys were being gassed by the Germans.”
Dr. Lerner contrasted the Covid response to the response to the polio vaccine.
The polio vaccine underwent preliminary testing, and then widespread testing, in the 1950s, with broad public acceptance.
With Covid, “faith in the scientific process got lost,” Dr. Lerner said.
That does not bode well for the next pandemic, Dr. Harper said.
“There’s going to be another pandemic,” he said. “And if we have to fight it without public trust, that’s the worst possible response.”
Health
Dementia risk signals could lie in simple blood pressure readings, researchers say
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Simple measurements taken during routine blood pressure checks could predict dementia risk years before symptoms appear.
That’s according to new research presented this week at the American College of Cardiology’s Annual Scientific Session in Louisiana.
The findings draw on two studies led by researchers at Georgetown University, which suggest that monitoring how blood vessels age and stiffen over time can provide a window into future cognitive health.
LURKING DEMENTIA RISK EXPOSED BY BREAKTHROUGH TEST 25 YEARS BEFORE SYMPTOMS
Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age, and half of U.S. adults have high blood pressure (hypertension).
Scientists believe that efforts to better address hypertension, a key contributor to heart disease and a risk factor for dementia, could affect both cardiac and brain health.
Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age. Meanwhile, half of U.S. adults have high blood pressure. (iStock)
“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health,” Dr. Newton Nyirenda, the study’s lead author and an epidemiologist at Georgetown University in Washington, said in a press release.
The research focused on two metrics, the pulse pressure-heart rate index and estimated pulse wave velocity. Both were calculated using data collected during standard doctor visits, such as heart rate, age and blood pressure.
“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health.”
Researchers examined five years of data patterns for more than 8,500 people in the SPRINT trial, a large study of adults 50 years and older with hypertension. In the follow-up, 323 of the participants developed probable dementia.
HIDDEN BRAIN CONDITION MAY QUADRUPLE DEMENTIA RISK IN OLDER ADULTS, STUDY SUGGESTS
In one study, the team found the pulse pressure-heart rate index was a strong independent predictor of dementia risk in adults over 50. For participants under 65, every one-unit increase was associated with a 76% higher risk of developing dementia.
For participants under 65, an increase in the pulse pressure-heart rate index was associated with a 76% higher risk of developing dementia. (iStock)
The second study found that adults with consistently elevated or rapidly increasing pulse wave velocity were more likely to develop dementia than those with stable velocity, even after accounting for factors like smoking, gender and cardiovascular history.
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“Our findings suggest that vascular aging patterns may provide meaningful insight into future dementia risk,” said Nyirenda. “This reinforces the idea that managing vascular health earlier in life may influence long-term brain health.”
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The team emphasized that clinicians should tailor risk assessments and treatment strategies to the individual.
Further studies are needed to confirm these parameters and determine whether changing vascular aging trajectories reduces dementia risk. (iStock)
“You don’t want to wait until a patient starts manifesting cognitive decline before you act,” said senior study author Sula Mazimba, an associate professor at the University of Virginia.
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Researchers noted the study could not establish causation. Other limitations included the fact that participants already had hypertension and elevated cardiovascular risk, meaning the findings may not apply to people without those conditions.
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Further studies are needed to confirm these findings and to determine whether improving blood vessel health over time could reduce dementia risk.
Health
Everything You Need To Know About Zepbound for Weight Loss, Including Costs
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Health
‘Gas station heroin’ banned in another state amid nationwide crackdowns
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A dangerous substance dubbed “gas station heroin” continues to alarm medical professionals, with more states making moves to restrict or ban tianeptine.
Fourteen states have officially classified the tricyclic antidepressant as a Schedule I controlled substance.
Connecticut is the latest state to crack down, officially banning the sale and use of the substance starting on Wednesday.
HEALTH OFFICIALS WARN OF DANGEROUS SUBSTANCE AVAILABLE IN STORES ACROSS THE NATION
Tianeptine, which can produce euphoria in higher doses, can be more potent than morphine and addictive opioids, according to the U.S. Food and Drug Administration.
Some countries have taken steps to restrict how tianeptine is prescribed or dispensed, and have even revised the labels to warn people of its potential addictive qualities.
Tianeptine can be more potent than morphine and addictive opioids. (iStock)
Misuse of tianeptine can cause severe adverse health effects, including respiratory depression, severe sedation and death, according to the Drug Enforcement Administration.
Some companies market the drug as an aid for pain, anxiety and depression, or as a means of improving mental alertness in a pill, powder, salt or liquid form.
The products are typically sold at convenience stores, gas stations, vape shops and online retailers, and go by names like Tianaa, ZaZa, Neptune’s Fix, Pegasus and TD Red.
Connecticut is the 15th state to classify tianeptine as a Schedule I controlled substance. (Markus Scholz/picture alliance via Getty Images)
Connecticut Lt. Gov. Susan Bysiewicz said in a press release that the schedule change is a necessary step to combat addiction.
“With false marketing that led consumers to believe these are safe products, and with candy-like flavor options, these substances posed a clear threat to those battling substance-use disorder and our youngest residents,” she added.
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The Nutmeg State also added Mitragyna speciosa (kratom), 7-hydroxymitragynine, Bromazolam, Flubromazolam, Nitazenes and Phenibut to the schedule classification.
Earlier this month, FDA Commissioner Martin Makary penned a letter sounding the alarm on what he called a “dangerous and growing health trend.”
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“I am very concerned,” Makary wrote. “I want the public to be especially aware of this dangerous product and the serious and continuing risk it poses to America’s youth.”
New York-based Robert Schwaner, M.D., vice chair of system clinical affairs at Stony Brook Emergency Medicine, told Fox News Digital that the FDA has never approved tianeptine as a dietary supplement.
“As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.” (Dekalb County Sheriff’s Office)
“The euphoria at low doses is primarily due to increased serotonergic activity from its serotonin reuptake effects. With increasing doses, the mu-opioid receptor stimulation may become lethal,” said Schwaner. “As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.”
Schwaner said he believes the substance requires national regulation due to its addictive qualities.
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“Acting at the same receptor as opioids, tianeptine has the potential for an individual to develop tolerance, subsequent dependence and withdrawal from its use,” he cautioned.
Fox News Digital reached out to the FDA for comment.
Fox News Digital’s Greg Wehner and Melissa Rudy contributed to this report.
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