Health
H.H.S. Scraps Studies of Vaccines and Treatments for Future Pandemics
The Trump administration has canceled funding for dozens of studies seeking new vaccines and treatments for Covid-19 and other pathogens that may cause future pandemics.
The government’s rationale is that the Covid pandemic has ended, which “provides cause to terminate Covid-related grant funds,” according to an internal N.I.H. document viewed by The New York Times.
But the research was not just about Covid. Nine of the terminated awards funded centers conducting research on antiviral drugs to combat so-called priority pathogens that could give rise to entirely new pandemics.
“This includes the antiviral projects designed to cover a wide range of families that could cause outbreaks or pandemics,” said one senior N.I.H. official who spoke on condition of anonymity for fear of retaliation.
The vaccine research also was not focused on Covid, but rather on other coronaviruses that one day might jump from animals to humans.
Describing all the research as Covid-related is “a complete inaccuracy and simply a way to defund infectious disease research,” the official said. Robert F. Kennedy Jr., the health secretary, has said that the N.I.H. is too focused on infectious diseases, the official noted.
The funding halts were first reported by Science and Nature. The cancellations stunned scientists who had depended on the government’s support.
“The idea that we don’t need further research to learn how to treat health problems caused by coronaviruses and prevent future pandemics because ‘Covid-19 is over’ is absurd,” said Pamela Bjorkman, a structural biologist at Caltech who had been studying new vaccines.
The goal of the projects was to have vaccines and drugs ready if a new pandemic hit, rather than spending precious months developing them from scratch.
“In the last pandemic, we really were caught with our pants down,” said Paul Bieniasz, a virologist at Rockefeller University who was collaborating with Dr. Bjorkman.
“And if we don’t learn that lesson and prepare better for the next pandemic, we are unlikely to do better than we did last time.”
Dr. Bieniasz, Dr. Bjorkman and their colleagues were developing a vaccine that might protect against a wide range of coronavirus species.
The researchers discovered new strategies to coax the immune system to learn how to recognize molecular features common to more than just one type of virus. Results from animal experiments were promising.
But now, with their funds abruptly cut, the scientists said they doubted they could build on those results. Dr. Bieniasz said that the termination had left him “angry, disappointed, frustrated.”
Other scientists had been working on antiviral treatments, part of a program started in 2021.
With $577 million in support from the N.I.H., a nationwide network of labs had been studying how viruses replicate, and then searching for drugs that could block them.
The researchers focused on viral families that include some of the most worrisome pathogens known, such as Ebola and Nipah virus. Scientists had discovered a number of promising molecules and were advancing toward clinical trials.
Reuben Harris, a molecular virologist at UT Health San Antonio, said that the promising compounds uncovered by the program included an antiviral drug that stops Ebola and related viruses from entering cells.
“It could be deployed to help a lot of people fast,” Dr. Harris said.
It looked as if some compounds might work against a number of virus families. “It’s some of the most exciting science I’ve seen in my career,” said Nevan Krogan, a systems biologist at the University of California, San Francisco.
On Wednesday morning, Dr. Krogan and dozens of his colleagues gathered in a campus meeting room to review those results. And they also discussed what, if anything, they could do now.
“One student asked me, ‘Well, I have an experiment booked on this microscope tomorrow — can I do it?’” Dr. Krogan said. “And I’m like, ‘Well, I don’t know.’”
Dr. Harris said that, without ongoing support, the promising drugs he and others had found would not move into clinical trials. “It’s tragic — I don’t have too many words to describe that right now,” he said.
In 2023, Mr. Kennedy said that he wanted to take “a break” from infectious disease research to focus instead on chronic disease.
Jason McLellan, a virologist at the University of Texas at Austin who worked on the antiviral program, saw the cancellations of pandemic research as following through on that promise.
Dr. McLellan, whose earlier research was fundamental to the creation of Covid vaccines in 2020, said this week’s cuts made him wonder if he could continue studying pandemics in the United States.
“We’ve had conversations and are beginning to put plans into motion to gather more information,” he said, referring to the possibility of moving abroad.
“My lab is a structural virology lab that focuses on structure-based vaccine design,” he added. “If the focus is on chronic diseases, that doesn’t leave much funding for us.”
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Research continues to uncover new details on how fasting may help extend life.
A new study published in the journal Nature Communications investigated how intermittent fasting can boost longevity in small worms often used in aging research.
Researchers from the University of Texas Southwestern Medical Center in Dallas compared worms that were fed normally to those that underwent a 24-hour fast in early adulthood and were then fed again, according to a press release.
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The scientists measured a variety of factors, including stored fat, gene activity related to fat metabolism and lifespan.
The results showed that the life-boosting benefit did not depend on the fasting itself but on the body’s behavior after eating again.
Experts say sustainability is key when choosing a long-term weight-loss strategy. (iStock)
Study lead Peter Douglas, associate professor of molecular biology and a member of the Hamon Center for Regenerative Science and Medicine at UT Southwestern, suggested that these discoveries “shift the focus toward a neglected side of the metabolic coin – the re-feeding phase.”
“Our data suggest that the health-promoting effects of intermittent fasting are not merely a product of the fast itself, but are dependent on how the metabolic machinery recalibrates during the subsequent transition back to a fed state,” he said.
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“Our findings bridge a gap between lipid metabolism and aging research,” he added. “By targeting aging, the single greatest risk factor for human disease, we move beyond treating isolated conditions toward a preventive model of medicine that enhances quality of life for all individuals.”
Lauri Wright, director of nutrition programs at the University of South Florida’s College of Public Health, called this a “high-quality” study that adds an “important nuance to how we think about fasting and longevity.”
Intermittent fasting typically involves limiting meals to an eight-hour daily window or fasting every other day. (iStock)
The benefits of the refeeding phase after fasting were “especially interesting,” Wright, who was not involved in the study, told Fox News Digital.
“The researchers showed that longevity was linked to the body’s ability to turn off fat breakdown after fasting, allowing cells to restore energy balance,” she reiterated.
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“From a scientific standpoint, that’s a meaningful shift because it suggests fasting is not just about burning fat, but about metabolic flexibility.”
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Fasting may support longevity through triggering metabolic switching, enhancing cellular repair and stress resistance and improving markers like insulin sensitivity, research shows.
Limitations and cautions
Although this study provides “important insight” on the power of refeeding, Wright noted that the findings should be approached with caution, as the study was done on worms and cannot always be translated to humans.
“Additionally, it explains how a process might work in a controlled lab condition rather than real-world eating behaviors,” she added as a limitation. “Finally, the study is short-term and doesn’t give us the long-term translation on lifespan outcomes.”
The review found intermittent fasting was barely more effective than doing nothing, according to the study authors. (iStock)
Wright cautioned that fasting is “not a magic solution for longevity, and how you eat overall matters more than when you eat.”
“I advise, first and foremost, to focus on diet quality, including a variety of fruits and vegetables, healthy fats and minimally processed foods,” she said.
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For those who are considering fasting, it’s better to stick with a moderate plan — like a 12- to 14-hour overnight fast — rather than going to extremes, Wright said. After fasting, she recommends focusing on well-balanced meals.
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Several groups of people should be cautioned against fasting, according to Wright, including those with diabetes who are on insulin or hypoglycemic medications, those who are pregnant or breastfeeding, anyone with a history of eating disorders and older adults at risk of malnutrition.
Anyone considering intermittent fasting should consult with a doctor before starting.
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More than three million people travel to undergo cosmetic surgery each year, statistics show — but the potential savings come at a cost.
Most people opting to pursue this so-called “medical tourism” are chasing budget-friendly price tags.
International surgeries, such as hair transplants in Turkey, can cost as little as $4,000 to $5,000 compared to $20,000 to $30,000 in the U.S., but often come with extreme risks, according to board-certified plastic surgeon Dr. Sheila Nazarian of California.
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The doctor recently joined Lisa Brady on the “The FOX News Rundown” podcast to discuss the rising trend of medical tourism. One of the biggest risks, she said, is the lack of safety regulations in popular destinations like Mexico and Turkey.
As demand spikes in these medical tourism “mills,” there have been reports of non-medically trained staff performing procedures like hair transplants.
Most people opting to pursue “medical tourism” are chasing budget-friendly price tags. (iStock)
“I’ve heard that they [international clinics] are even recruiting people who maybe were taxi drivers and then putting them through their own training program … to become hair transplant technicians,” Nazarian said. “That’s how high the demand has become.”
In the U.S., medical school graduates are granted a “physician and surgeon” license, which means doctors — including pediatricians or OB-GYNs — can legally perform cosmetic surgeries, even if they didn’t receive specialized training for those procedures during residency, Nazarian noted.
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Instead of pinching pennies, the doctor recommended paying whatever amount is necessary to ensure quality treatment.
“People think of it as, you know, going to the mall. … It’s surgery, and surgery has risks,” she said. “You need to be with someone who not only can perform a beautiful surgery, but who can handle possible complications well.”
“You need to ask them: ‘What was your residency training in? And if you wanted to, would you be allowed to do this procedure in a hospital?’”
Aftercare is another critical factor in the success and safety of a cosmetic procedure, as the doctor emphasized that 20% of a surgical result depends on post-operative care.
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This can be difficult or even impossible to manage when a doctor is in a different time zone, she cautioned, or if the clinic disappears shortly after the procedure.
Nazarian also noted the importance of addressing the psychological component of plastic surgery, noting that no procedure will fix underlying unhappiness. The doctor said she uses screening questionnaires to ensure that patients are truly seeking self-improvement rather than a “cure” for deeper issues.
International surgeries, such as hair transplants in Turkey, can cost as little as $4,000 to $5,000 compared to $20,000 to $30,000 in the U.S., but often come with extreme risks. (iStock)
“If you’re not already generally very content with your life, a knife in my hand is not going to bring you there,” Nazarian said.
“The analogy I always give is you don’t want a paisley couch — you want a neutral couch and you can put paisley pillows on it,” she said, noting that a procedure should “make you look normal, God-given, athletic. And then you can change your clothes when the trends come and go.”
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Samuel Golpanian, M.D., a double board-certified plastic surgeon in Beverly Hills, said he has also seen an increasing number of patients undergoing cosmetic procedures abroad, sometimes with “devastating consequences.”
“The key is being extremely careful before embarking on this journey.”
“I’ve seen a wide range of complications, including infections, poor wound healing, significant scarring and tissue necrosis (skin death),” he told Fox News Digital. “These complications often lead to prolonged pain, ongoing medical problems, and significant additional costs to repair the damage.”
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Golpanian said he’s treated patients who received unsafe or non-medical-grade injectable materials, which can lead to serious long-term health issues.
One surgeon said he’s treated patients who received unsafe or non-medical-grade injectable materials, which can lead to serious long-term health issues. (iStock)
“I’ve also seen damage to underlying structures, asymmetry and results that are extremely difficult — sometimes impossible — to correct.”
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“That said, I’ve also seen some good outcomes, so it’s not all bad,” he noted. “The key is being extremely careful before embarking on this journey.”
Quick tips for safe ‘medical tourism’
Fully vet the surgeon. “Most surgeons will provide information about their education and training, but it’s important not to accept these claims at face value,” Golpanian said. “Verify them directly by contacting the institutions where they trained.”
Ask for references from prior patients. Ideally, it’s best to get references from U.S.-based patients who can speak candidly about both their experience and their results, the surgeonsaid.
Think beyond the cost. Golpanian emphasized the adage “you get what you pay for.” “Cost should take a back seat to experience, training, judgment and proven results,” he advised.
Be cautious about relying on before-and-after photos. These can be selective or even enhanced, Golpanian warned.
Keep aftercare in focus. “Make sure the practice emphasizes comprehensive follow-up care and has a clear, realistic post-operative plan in place.”
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