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Daily multivitamins might not help you live longer, study finds: 'No differences in mortality'

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Daily multivitamins might not help you live longer, study finds: 'No differences in mortality'

Approximately one-third of U.S. adults report taking multivitamins, data shows — but a new study suggests that the daily practice won’t extend longevity.

Researchers from the National Institutes of Health (NIH) analyzed more than 20 years’ worth of data from 400,000 healthy U.S. adults, concluding that taking multivitamins did not reduce mortality risk.

“The analysis showed that people who took daily multivitamins did not have a lower risk of death from any cause than people who took no multivitamins,” the researchers wrote in a press release from NIH. 

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“There were also no differences in mortality from cancer, heart disease or cerebrovascular diseases.”

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Approximately one-third of U.S. adults report taking multivitamins, data shows. (iStock)

Those who took daily multivitamins were actually found to have a 4% higher mortality risk, according to the study, which was published in JAMA Network Open on Wednesday.

The average age of participants was 61-½, and 164, 762 deaths occurred during the follow-up period.

“People who use multivitamins may have healthier lifestyles in general, and sicker patients may be more likely to increase their use of multivitamins.”

Results were adjusted for factors including race, ethnicity, education and nutrition.

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The study followed a 2022 analysis from the US Preventive Services Task Force, which concluded that there was “insufficient evidence” to determine whether multivitamin use improved mortality.

Woman taking pill

Those who took daily multivitamins were actually found to have a 4% higher mortality risk, according to the study, which was published in JAMA Network Open on Wednesday. (iStock)

By including larger numbers of participants and extending the follow-up for longer periods of time, the researchers aimed to account for potential biases that could have influenced the findings.

“For example, people who use multivitamins may have healthier lifestyles in general, and sicker patients may be more likely to increase their use of multivitamins,” they wrote in a press release from NIH.

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Pieter Cohen, associate professor of medicine at the Cambridge Health Alliance in Massachusetts, was not involved in the study but offered his feedback.

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“This study provides further evidence that taking multivitamins, even for 20 years or more, won’t extend your life,” he told Fox News Digital. 

“For healthy adults, there’s no reason to add on a multivitamin unless your doctor specifically recommends it.”

Doctor points out limitations

Dr. Brett Osborn, a Florida neurologist and longevity expert, was also not involved in the study but weighed in on the findings.

Dr. Brett Osborn

Dr. Brett Osborn, a Florida neurologist and longevity expert with Senolytix, is a proponent of daily multivitamins. (Dr. Brett Osborn)

“Key aspects of the study include its observational nature, the absence of a control group, and the variability in multivitamin formulations used by participants,” he said in an email to Fox News Digital.

(The researchers also acknowledged these limitations in their discussion of the study results.)

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“Most multivitamins contain a broad spectrum of vitamins and minerals, but the concentrations can vary widely across brands and formulations,” a doctor said.  (iStock)

“Observational studies like this one can suggest associations or correlations, but cannot prove causation due to the potential for confounding variables influencing both multivitamin use and mortality outcomes,” Osborn said. 

While the researchers noted that they had adjusted for factors such as demographics, lifestyle behaviors and health status, Osborn said, “residual confounding remains a concern.”

The doctor also noted that lack of a control group makes it difficult to compare outcomes.

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“Without a control group, it’s challenging to separate the effects of multivitamins from those of other health behaviors or baseline health conditions that could influence mortality,” Osborn said.

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The study also does not include controls for the specific formulation or dosage of multivitamins taken by participants, the doctor noted. 

hand holds out pills

The study highlights the importance of “rigorous scientific inquiry” into the health benefits of multivitamins, a doctor said. (iStock)

“Most multivitamins contain a broad spectrum of vitamins and minerals, but the concentrations can vary widely across brands and formulations,” he said. 

“Many commercially available multivitamins may not provide optimal levels of nutrients required for health benefits, potentially diluting any potential effects on longevity.”

                       

In his practice, Osborn said, he recommends a multi-capsule daily multivitamin to his patients. 

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Vitamin usage is just one aspect of longevity, the doctor pointed out, along with genetics, lifestyle, socioeconomic status and access to health care, among other factors.

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“The multifactorial nature of longevity means that isolating the impact of multivitamins alone is complex and challenging, if not impossible,” Osborn said. 

“There are just too many potentially confounding variables.”

The study highlights the importance of “rigorous scientific inquiry” into the health benefits of multivitamins, according to the doctor.

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Vitamin usage is just one aspect of longevity, a doctor pointed out, along with genetics, lifestyle, socioeconomic status and access to health care. (iStock)

“In my opinion, multivitamins should be taken, as most Americans are malnourished — certainly not calorically, but in the context of vitamins and minerals.”

Looking ahead, the researchers emphasized the importance of measuring multivitamins’ impact on mortality in more diverse populations with different medical conditions and dietary habits.

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“It is important to evaluate multivitamin use and risk of death among different kinds of populations, such as those with documented nutritional deficiencies, as well as the potential impact of regular multivitamin use on other health conditions associated with aging,” they wrote.

Fox News Digital reached out to the study researchers for comment, as well as the vitamin manufacturers PharmaVite (NatureMade), Nestlé Health Science (Garden of Life and Nature’s Bounty), and Life Extension.

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How The Great British Bake Off Host Alison Hammond Lost 150 Lbs Naturally

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How The Great British Bake Off Host Alison Hammond Lost 150 Lbs Naturally


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One state leads country in human bird flu with nearly 40 confirmed cases

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One state leads country in human bird flu with nearly 40 confirmed cases

A child in California is presumed to have H5N1 bird flu, according to the San Francisco Department of Public Health (SFDPH).

As of Dec. 23, there had been 36 confirmed human cases of bird flu in the state, according to the California Department of Public Health (CDPH).

This represents more than half of the human cases in the country.

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The latest pediatric patient, who lives in San Francisco, experienced fever and conjunctivitis (pink eye) as a result of the infection.

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The unnamed patient was not hospitalized and has fully recovered, according to the SFDPH.

A child in California is presumed to have H5N1 bird flu, according to the San Francisco Department of Public Health. (iStock)

The child tested positive for bird flu at the SFDPH Public Health Laboratory. The U.S. Centers for Disease Control and Prevention (CDC) will perform additional tests to confirm the result.

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It is not yet known how the child was exposed to the virus and an investigation is ongoing.

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“I want to assure everyone in our city that the risk to the general public is low, and there is no current evidence that the virus can be transmitted between people,” said Dr. Grant Colfax, director of health, in the press release. 

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“We will continue to investigate this presumptive case, and I am urging all San Franciscans to avoid direct contact with sick or dead birds, especially wild birds and poultry. Also, please avoid unpasteurized dairy products.” 

Samuel Scarpino, director of AI and life sciences and professor of health sciences at Northeastern University in Boston, is calling for “decisive action” to protect individuals who may be in contact with infected livestock and also to alert the public about the risks associated with wild birds and infected backyard flocks. 

Chick bird flu test

An infectious diseases expert called for “decisive action” to alert the public about the risks associated with wild birds and infected backyard flocks.  (iStock)

“While I agree that the risk to the broader public remains low, we continue to see signs of escalating risk associated with this outbreak,” he told Fox News Digital.

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Experts have warned that the possibility of mutations in the virus could enable person-to-person transmission.

     

“While the H5N1 virus is currently thought to only transmit from animals to humans, multiple mutations that can enhance human-to-human transmission have been observed in the severely sick American,” Dr. Jacob Glanville, CEO of Centivax, a San Francisco biotechnology company, told Fox News Digital.

Split image of cows and bird flu vial

As of Jan. 10, there have been a total of 707 infected cattle in California, per reports from the California Department of Food and Agriculture. (iStock)

“This highlights the requirement for vigilance and preparation in the event that additional mutations create a human-transmissible pandemic strain.”

As of Jan. 10, there have been a total of 707 infected cattle in California, per reports from the California Department of Food and Agriculture (CDFA).

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In the last 30 days alone, the virus has been confirmed in 84 dairy farms in the state.

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Chronic Pain Afflicts Billions of People. It’s Time for a Revolution.

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Chronic Pain Afflicts Billions of People. It’s Time for a Revolution.

“In the beginning, everyone thought they were going to find this one breakthrough pain drug that would replace opioids,” Gereau said. Increasingly, though, it’s looking like chronic pain, like cancer, could end up having a range of genetic and cellular drivers that vary both by condition and by the particular makeup of the person experiencing it. “What we’re learning is that pain is not just one thing,” Gereau added. “It’s a thousand different things, all called ‘pain.’”

For patients, too, the landscape of chronic pain is wildly varied. Some people endure a miserable year of low-back pain, only to have it vanish for no clear reason. Others aren’t so lucky. A friend of a friend spent five years with extreme pain in his arm and face after roughhousing with his son. He had to stop working, couldn’t drive, couldn’t even ride in a car without a neck brace. His doctors prescribed endless medications: the maximum dose of gabapentin, plus duloxetine and others. At one point, he admitted himself to a psychiatric ward, because his pain was so bad that he’d become suicidal. There, he met other people who also became suicidal after years of living with terrible pain day in and day out.

The thing that makes chronic pain so awful is that it’s chronic: a grinding distress that never ends. For those with extreme pain, that’s easy to understand. But even less severe cases can be miserable. A pain rating of 3 or 4 out of 10 sounds mild, but having it almost all the time is grueling — and limiting. Unlike a broken arm, which gets better, or tendinitis, which hurts mostly in response to overuse, chronic pain makes your whole world shrink. It’s harder to work, and to exercise, and even to do the many smaller things that make life rewarding and rich.

It’s also lonely. When my arms first went crazy, I could barely function. But even after the worst had passed, I saw friends rarely; I still couldn’t drive more than a few minutes, or sit comfortably in a chair, and I felt guilty inviting people over when there wasn’t anything to do. As Christin Veasley, director and co-founder of the Chronic Pain Research Alliance, puts it: “With acute pain, medications, if you take them, they get you over a hump, and you go on your way. What people don’t realize is that when you have chronic pain, even if you’re also taking meds, you rarely feel like you were before. At best, they can reduce your pain, but usually don’t eliminate it.”

A cruel Catch-22 around chronic pain is that it often leads to anxiety and depression, both of which can make pain worse. That’s partly because focusing on a thing can reinforce it, but also because emotional states have physical effects. Both anxiety and depression are known to increase inflammation, which can also worsen pain. As a result, pain management often includes cognitive behavioral therapy, meditation practice or other coping skills. But while those tools are vital, it’s notoriously hard to reprogram our reactions. Our minds and bodies have evolved both to anticipate pain and to remember it, making it hard not to worry. And because chronic pain is so uncomfortable and isolating, it’s also depressing.

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