Connect with us

Fitness

Exercise Scientist Reveals His System for Ranking Muscle-Building Supplements

Published

on

Exercise Scientist Reveals His System for Ranking Muscle-Building Supplements

Dr. Eric Trexler, PhD – researcher, coach, and professional bodybuilder – recently appeared on the Renaissance Periodization podcast to share his evidence-based tier system for ranking muscle-building supplements. He emphasised that supplement rankings are goal-dependent, varying based on what you’re aiming to achieve with your training and supplementation.

Dr. Trexler then outlined his tiered approach specifically for those focused on gaining muscle and building strength, categorising supplements into five distinct tiers and providing examples of each along the way.

Tier-1 Supplements

‘Tier-1 basically means we have strong evidence. We know what this thing does, and what it does is good,’ says Dr. Trexler, who explains that for muscle-building, tier-1 supplements are in a class of their own. ‘It’s a short list – it’s creatine [assuming you’re not a non-responder] and it’s protein.’

Dr. Trexler caveats that protein supplements could be redundant if you’re able to get enough of the macronutrient from your diet. ‘If you’re eating enough from your food, who cares, forget it.’

Tier-2 Supplements

Dr. Trexler believes tier-2 supplements are the most interesting. ‘There is some evidence related to the supplement for the outcome we’re interested in, and it actually looks pretty good, but it’s not on tier-one because it has some shortcoming,’ he says. ‘Maybe the initial evidence is pretty good, but I’d like to see more of it before I get super stoked.’

Advertisement

He adds that in some cases, the evidence for a supplement may be very strong, but in the real world, its effects are small and inconsistent, or only work in people with deficiencies. ‘You can have a really solid evidence-based justification for this. However, you’re likely going to have to acknowledge this is a really marginal effect. Maybe this only matters for a competitive athlete.’

The supplements Dr. Trexler would include in tier-2 are: sodium bicarbonate, citrulline malate and nitric oxide supplements.

Controversially, Trexler says he would also put caffeine, one of the most heavily relied-on ergogenic aids in existence, into tier-2. ‘There are meta-analyses and umbrella reviews indicating it should have a positive effect on things like strength, strength endurance, and power. But caffeine is probably better for endurance sport than it is for resistance exercise.’

He does point out the potential dark side of becoming too reliant on the pre-workout shot of espresso. ‘We don’t know when you get to that point when you say, “I wouldn’t dare work out without my pre-workout.” Is that because it’s still giving you an ergogenic [performance-enhancing] effect? Or is it because caffeine withdrawal gives you an ergolytic effect and your performance sucks?’

(Ergolytic is science-talk for something that negatively impacts your performance.)

Advertisement

Tier-3 Supplements

‘Tier-3 is where the vast majority of supplements live’, Trexler says. ’It’s the tier where I tell someone I do not have enough evidence to say that there is a defensible use case for this but I also don’t have enough hard evidence to tell you there is no way this will work.’

So, if it’s not in any of the other tiers, with enough evidence for or against it’s use, consider it tier-3.

While Dr. Trexler doesn’t clearly define tier-3 supplements as he does with other tiers, examples might include Beta-alanine, which shows some promise for improving endurance but has inconsistent effects on muscle-building and strength, or Branched-chain amino acids (BCAAs). Once highly popular, recent research suggests their benefits are limited compared to complete proteins or essential amino acids, placing them in the tier-3 category.

Tier-4 Supplements

Dr. Trexler believes tier-4 is a tricky one – it’s the first category where we should consider actively swerving the compounds in question. ‘This is where we have evidence of a null effect. I can look at studies on it and say this is not going to achieve what you want it to achieve,’ says Dr. Trexler. His host, Dr. Mike Israetel, also an exercise scientist, offers a more concise and memorable definition: ‘It’s not hurting you; it just doesn’t do shit

When it comes to building strength and size, Trexler would include previously popular supplements like glutamine in tier-4. ‘For getting jacked and performing better, I think we’ve pretty much shut the book on glutamine.’

Advertisement

He’d also place arginine – an amino acid that was once popular in pre-workout mixtures and touted as a ‘pump enhancer’ – in tier-4, alongside some testosterone boosters and modern ‘new-and-improved’ creatines like ethyl ester and alkaline varieties, saying they don’t justify their cost when tier-1’s cheaply available creatine monohydrate is an option.

Tier-5 Supplements

Tier-5 is the group that Dr. Trexler strongly advises you avoid. ‘[These are] supplements where we have evidence that one of two things is going to happen – either this is going to literally harm your performance, or it is going to harm you.’

Trexler says he would include compounds like DMAA, a chemical extract previously included in now-banned pre-workout supplements such as the highly-memed JACK-3D. He jokes that although these compounds were widely available and not previously banned, the aim of manufacturers at the time seemed to be to get as close as possible to the effects of methamphetamine.

Another tier-5 chemical that was once the stimulant of choice for many bodybuilders is ephedrine. ‘It was the era of [high stimulant] pre-workouts. However, there were serious adverse events reported. I believe that there were a couple of deaths.’ Thankfully, sporting organisations and federations have helped to pave the way to a slightly safer supplement industry. ‘Once it’s banned by all the big federations, I say all right, we’re going to tier-5…’

Advertisement

With almost 18 years in the health and fitness space as a personal trainer, nutritionist, breath coach and writer, Andrew has spent nearly half of his life exploring how to help people improve their bodies and minds.    

As our fitness editor he prides himself on keeping Men’s Health at the forefront of reliable, relatable and credible fitness information, whether that’s through writing and testing thousands of workouts each year, taking deep dives into the science behind muscle building and fat loss or exploring the psychology of performance and recovery.   

Whilst constantly updating his knowledge base with seminars and courses, Andrew is a lover of the practical as much as the theory and regularly puts his training to the test tackling everything from Crossfit and strongman competitions, to ultra marathons, to multiple 24 hour workout stints and (extremely unofficial) world record attempts.   

 You can find Andrew on Instagram at @theandrew.tracey, or simply hold up a sign for ‘free pizza’ and wait for him to appear.

Advertisement

Fitness

Hate exercise? Fitness expert Annie Deadman shares 3 moves to do when you have no time

Published

on

Hate exercise? Fitness expert Annie Deadman shares 3 moves to do when you have no time

Hello you lovely lot. Right, I have 500 words and I’m not going to use them for persuasion or coercion, because that doesn’t work. I want to explain what the point of exercise is. All facts, no emotion. Then you can make up your own mind.

The first fact is that many people view exercise purely as a means to lose weight. So that 45 minutes of exertion three to four times a week becomes only about burning calories.

Continue Reading

Fitness

An osteopath says this is the one thing he wished more people knew so his treatment table wasn’t so busy in January

Published

on

An osteopath says this is the one thing he wished more people knew so his treatment table wasn’t so busy in January

Andy McIntyre (BOst, MSc) says his clinic is always fully booked in January.

The associate osteopath from The Livewell Clinic in London says the reason injuries tend to always flare up at the start of the year is simple.

Continue Reading

Fitness

This Popular Celebrity Workout Actually Has Science to Back It

Published

on

This Popular Celebrity Workout Actually Has Science to Back It

Lack of time is often the main reason people don’t exercise regularly. But a type of interval workout recently popularized by actress Jessica Biel could be the solution – with research showing it can improve fitness faster than traditional, steady-pace workouts, such as jogging or cycling.

The Norwegian 4×4 workout has traditionally been used by athletes. It’s a form of high-intensity interval training (Hiit) that involves four-minute sets of very intense cardio exercise, followed by three minutes of very light exercise.

A typical training session includes a five-minute warm-up, four high-intensity intervals and a five-minute cool-down.

Related: There’s One Simple Trick to Boost The Health Benefits of Your Run

The 4×4 workout format follows the same format as other Hiit workouts, which alternate periods of high-intensity exercise with periods low-intensity exercise (or rest). Most Hiit workouts involve work intervals that last anything from ten seconds up to a couple of minutes. In contrast, the 4×4 workout employs four minute work periods, which raises your heart rate for longer than most Hiit protocols.

Advertisement

Decades of research has shown that regular Hiit workouts are often more effective than moderate-intensity workouts (such as running or cycling at a steady pace continuously) in improving cardiovascular fitness and other health outcomes (such as improving blood sugar and cholesterol levels). Hiit is even effective for improving health in adults with type 2 diabetes and cardiovascular disease.

Hiit also offers these benefits with less training time than traditional endurance training. A 2008 study showed that as few as six Hiit sessions over two weeks improved the muscles’ endurance capacity.

Several studies have also explored the benefits of the 4×4 protocol. For example, an eight-week study showed that the 4×4 workout produced greater aerobic fitness improvements than 45-minute moderate-intensity running sessions.

The reason the 4×4 workout specifically is so effective for improving cardiovascular fitness is because the four-minute intervals are intense enough to maximally challenge your heart and lungs while minimizing muscle fatigue. This helps improve your maximum oxygen uptake (or VO₂ max), which is the highest rate at which your body can take in, transport and use oxygen during intense exercise.

Advertisement

VO2 max is considered the gold standard measure of cardiovascular fitness. Higher VO₂ max values are associated with reduced risk of cardiovascular disease and premature death, and better overall health.

During a 4×4 workout you’ll spend roughly 16 minutes close to you maximum heart rate. This means that it can improve VO2 max more effectively than longer duration, moderate-intensity workouts.

Woman on stationary bike as seen through gym quipment
The intensity of the 4×4 workout can improve your cardiovascular health. (Mike Cox/Unsplash)

Choosing the right workout

For people with busy schedules, Hiit is a time-efficient option because it offers the same health and fitness benefits as longer workouts with less training time. However, a 4×4 Hiit session still lasts between 35–40 minutes, which might be too long for some people.

For those seeking a shorter workout option, the 10×1 Hiit protocol is a suitable alternative as it can be completed in just 30 minutes – including warm-up and cool-down periods.

This involves doing ten one-minute intervals of intense exercise. Each minute of hard work is followed by a minute of light exercise or complete rest.

But while this protocol also improves VO₂ max, the shorter work periods must be performed at a much higher intensity than the four-minute intervals to challenge the cardiovascular system. This could make it difficult to pace yourself consistently during each interval.

Advertisement

Another Hiit workout option is sprint interval training. This involves exercising as hard as possible for ten to 20 seconds – followed by three minutes of recovery. These sprints can be done running, cycling or even rowing.

One 12-week study found that participants who performed three, 20-second sprints (followed by three-minute recovery periods) just three times a week significantly improved their cardiovascular fitness compared to those doing longer, steady-state workouts.

However, the 4×4 workout has been shown to produce better gains in aerobic fitness than sprint interval training.

Although most research shows that Hiit produces rapid health and fitness benefits, it’s difficult to know exactly how effective it is in the real world because most studies use specialized equipment and are supervised by researchers. As such, study results may not reflect what happens when people train on their own.

The very demanding nature of Hiit may also make it less enjoyable for some people – particularly those who aren’t used to intense exercise. This is important, because lower enjoyment is linked to poorer motivation and lower likelihood of sticking to a workout program.

Advertisement

Also, while Hiit is often promoted as exciting and time efficient, its novelty may wear off. What feels new and motivating at the start may become tiring or repetitive, especially without variety or support. As a result, some people may struggle to stick with a workout program after a few weeks.

Long-term fitness improvements come from training consistently. For that reason, it’s essential to choose a form of exercise that you enjoy.

If Hiit is less appealing to you than alternatives, such as steady jogging, cycling or weightlifting, it may be more effective to focus on workouts you’re more likely to stick with.

You don’t always have to push yourself to the limit to improve your health and fitness. Even consistent activity, such as accumulating around 7,000 steps a day, can still lead to meaningful physical and mental health benefits.

The Norwegian 4×4 protocol is just the latest popular Hiit workout. While it can offer many health and fitness benefits for you in a short period of time, it might not suit your needs – so be sure to pick a workout that best suits your goals and schedule.The Conversation

Paul Hough, Lecturer Sport & Exercise Physiology , University of Westminster

Advertisement

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Continue Reading

Trending