The Iowa high school football regular season is over, and now it’s time for the playoffs.

Last week, teams in Class 3A, 4A and 5A wrapped up their regular seasons, while teams in Class A, 1A, 2A and 8-player kicked off the postseason with first-round games. That means it’s all win-or-go-home from here on out, with 16 teams remaining in all seven classes.

This week’s schedule is packed with exciting matchups.

We’re picking 10 games each week of the IHSAA season and attempting to predict the outcomes. Each week, we’ll provide an update on how successful – or unsuccessful – those predictions are.

We finished the regular season with a 63-27 record in our picks, after going 9-1 last week.

Here are our predictions for some of the best Iowa high school football Round of 16 games.

Ankeny Centennial at Johnston

This hasn’t been the Jaguars’ season, and the Dragons have come out on top in games that mattered most. So long as Johnston does what has worked against teams like Ankeny and Southeast Polk, the Dragons should advance to the quarterfinals. Johnston 30, Ankeny Centennial 13

Central DeWitt at Wahlert Catholic

On paper, Central DeWitt looks like the more complete team in this matchup, but Wahlert Catholic came out on top when these teams met in the regular season. That game was less than a month ago, and there’s a chance that the Sabers get their revenge in the postseason. Wahlert Catholic 19, Central DeWitt 14

Dallas Center-Grimes at Sioux City East

The Black Raiders boast a 2,000-yard passer in Cal Jepsen; the Mustangs balance a trio of receivers with Ozzie Grimm’s success in the ground game. If Dallas Center-Grimes can come out with a couple of turnovers, the Mustangs could end Sioux City East’s season. Dallas Center-Grimes 27, Sioux City East 20

More: How Dallas Center-Grimes football is out to a fast start after moving to Class 5A

Fort Dodge at Newton

Both teams enter this matchup with 8-1 records, and Fort Dodge has some difference makers on both sides of the ball. But the Cardinals are battle-tested, and Nick Milburn is a defender who can keep any opposing offense on its toes. Newton 35, Fort Dodge 21

Glenwood at North Polk

If the Comets are healthy, they should win this first-round game. But North Polk had to go without starting quarterback James Armstrong in the regular season finale against Gilbert, and things didn’t go well. Because Glenwood relies a lot on the run and the Comets struggled in that department against Gilbert, the Rams might have the advantage in this one. Glenwood 28, North Polk 17

Iowa City West at Cedar Falls

The Trojans look like a tough team to beat on both sides of the ball, but Cedar Falls has walked away with some upsets this season. Iowa City West should have the advantage with the number of impactful players on offense, though. Iowa City West 28, Cedar Falls 14

More: 5 Iowa high school football surprises heading into the 2025 IHSAA playoffs

Southeast Polk at Ankeny

It’s difficult to imagine a playoff bracket without Southeast Polk making a deep run, but Ankeny looks like the stronger team on paper. Between Kael Roush and Daniel Larmie – and company – on offense and a defense that capitalizes on turnovers, the Hawks could send the Rams packing early. Ankeny 30, Southeast Polk 16

Underwood at West Marshall

Underwood’s offense runs through Garrett Luett, and it’s been difficult for opposing defenses to slow him down. But West Marshall’s defense loves to get after the quarterback, and if they can alter the Eagles’ game plan, that could be good enough for a win. Underwood 27, West Marshall 17

Van Meter at Roland-Story

Experience means a lot at this point in the season, and the Bulldogs have plenty after making it to the state semifinals last season. Van Meter should benefit from that senior leadership, as well as sophomore Christian Williams’ dominance on both sides of the ball. Van Meter 14, Roland-Story 12

Waukee at Iowa City Liberty

The Warriors pulled out some unlikely wins at the end of the season, but Iowa City Liberty came up with some upsets, as well. The Lightning’s defense, though, tends to capitalize on opponents’ mistakes, and that should benefit Liberty. Iowa City Liberty 35, Waukee 24

Alyssa Hertel is the college sports recruiting reporter for the Des Moines Register. Contact Alyssa at ahertel@dmreg.com or on Twitter @AlyssaHertel.