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How Patient Data Brings Life-Changing Medicine to Central Pennsylvania – UPMC & Pitt Health Sciences News Blog

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How Patient Data Brings Life-Changing Medicine to Central Pennsylvania – UPMC & Pitt Health Sciences News Blog


Each year, thousands of patients visit UPMC hospitals, outpatient centers and specialty and primary care offices – generating thousands of datasets in the process. Whether it’s demographic information, imaging, lab results, signs and symptoms, family histories or treatment outcomes, there are countless stories for the masses of de-identified data to tell – and physicians like Hemal Gada, M.D., president, UPMC Heart and Vascular Institute in Central Pa., are using artificial intelligence to unravel those narratives.  

“Applying machine learning and artificial intelligence to big datasets is a burgeoning field of medical research. In the next five years, we’ll use predictive modeling to precisely define the progression of diseases like cancer and heart disease,” Dr. Gada said.  

Certain geographic, demographic, cultural, genetic and generational factors contribute to how diseases develop, progress and affect our bodies. For example, the social and environmental factors that drive the development and progression of heart disease will vary between someone living in rural Appalachia and someone living in an urban or suburban environment.  

According to Dr. Gada, machine learning, a type of computer program, allows researchers to identify patterns in vast amounts of patient data. By identifying these trends in a specific subset of de-identified patient data from central Pennsylvania, Dr. Gada hopes to identify the precise factors that drive disease progression in the region – which could someday lead to specialized clinical trials and treatment approaches.  

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Dr. Gada and his colleagues published a study in The American Journal of Cardiology that utilized this machine learning approach to understand more about the characteristics of the stages of aortic stenosis for people living in central Pennsylvania. Patients with this condition have a heart valve that doesn’t open fully, which reduces blood flow from the heart to the aorta and to the rest of the body. If left untreated, chest pain and shortness of breath can develop, along with a host of other cardiac challenges – including clotting, heart failure, and stroke.  

Historically, aortic stenosis patients have typically been assigned to three categories – mild, moderate, and severe. Severe patients typically undergo transcatheter aortic valve replacement (TAVR), but milder severity patients do not. Cardiologists have debated whether moderate aortic stenosis might benefit from a TAVR procedure due to their higher risk for poor outcomes. 

Using echocardiograms and patient data from more than 61,000 aortic stenosis (AS) patients at UPMC Heart and Vascular Institute in Central Pa, Dr. Gada and his colleagues developed an algorithm to study the medical histories of these patients over time — How long after diagnosis before they were readmitted to the hospital? What other co-occurring diseases did they have? What signs did the body give to signal that a poor outcome or hospital readmission could be imminent?  

The research team determined that moderate AS patients living in central Pennsylvania who have end-stage kidney disease or atrial fibrillation were at the highest risk for poor outcomes. According to Dr. Gada, these patients could need an intervention like the TAVR procedure, sooner rather than later.  

While these findings are intriguing, Dr. Gada said this research is hypothesis-generating, meaning it will lead to the development of clinical trials – some of which are already underway.  

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Artificial intelligence-driven research often leads to more questions than it does answers, but the next time you’re at the doctor’s office and answering questions about your symptoms and health history, remember that you could shape the future of medicine simply by showing up and getting the care you need.  

“Your data, which is de-identified in the research process, is just one piece of a much larger puzzle,” Dr. Gada said. “This data doesn’t have to be stagnant; it can help us develop personalized approaches to medicine in our community and determine what health challenges the citizens of our region face. We’re just beginning to scratch the surface of how artificial intelligence can transform health care in central Pennsylvania.”   

 





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Were ICE agents at the Pa. Farm show? Here’s what officials say

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Were ICE agents at the Pa. Farm show? Here’s what officials say


Online speculation about the presence of U.S. Immigrations and Customs Enforcement (ICE) agents at the 2026 Pennsylvania Farm Show has sparked a growing spread of misinformation.

Multiple posts on Facebook and TikTok have stated that undercover or plain clothes ICE agents are walking around the farm show and staying at local hotels without naming a source for their information.

“These rumors are false,” Pa. Department of Agriculture Press Secretary Shannon Powers told PennLive on Sunday. “The Department of Agriculture has not found any ICE personnel working on or near the Farm Show complex.”

A PennLive reporter walking around the complex on Saturday did not see any ICE agents.

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Powers also said ICE has not rented or reserved event space or an exhibit booth in the Pennsylvania Farm Show Complex for the Farm Show.

There are law enforcement personnel on the property, but they are focused on safety and security of Farm Show visitors, Powers said.

Pennsylvania State Police troopers are stationed and patrolling the Farm Show complex and parking lots to keep visitors safe, working in conjunction with the Pennsylvania Emergency Management Agency, Farm Show Security, Capitol Police, local municipal police departments and Harrisburg Fire Police.

Discourse about ICE has ramped up since Renee Good was fatally shot by an ICE officer in Minneapolis last week. Good was a 37-year-old mother of three.

In the last several months, the Department of Homeland Security has heavily increased immigration enforcement, characterized by arrests of undocumented immigrants, a social media campaign and crackdowns on protests.

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Small Pennsylvania town battles billionaire buying up homes and shops

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Small Pennsylvania town battles billionaire buying up homes and shops


Residents of a wealthy Pennsylvania village confronted developers this week after learning that a billionaire has quietly bought up much of the town’s commercial core, fueling fears that one family now wields outsized control over its future.

The backlash centers on Jeff Yass, Pennsylvania’s richest man, whose family has spent more than $15 million acquiring homes, storefronts, and civic properties in Gladwyne, a community of just under 5,000 residents and where median home prices top $2.3 million.

At a packed public meeting in a school auditorium, developers working with Yass unveiled their first detailed redevelopment plans for the village center.

The moment that drew both applause and skepticism from residents alarmed by shuttered businesses, rising rents, and unanswered questions about the scope of the billionaire-backed project.

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Standing before the crowd, Andre Golsorkhi, founder and CEO of design firm Haldon House, unveiled a sweeping redevelopment plan crafted in partnership with Yass and his wife, Janine. 

Golsorkhi framed the effort as a ‘community impact project,’ insisting the billionaire family’s intentions were rooted in preservation rather than profit.

But for a town already rattled by closed storefronts, the presentation drew plenty of suspicion and unease.

Over the past several years, Haldon House and the Yass family have acquired multiple properties clustered around the intersection of Youngs Ford and Righters Mill Roads – effectively Gladwyne’s commercial heart.

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Gladwyne, Pennsylvania, a village of just under 5,000 residents, is suddenly at the center of a high-stakes fight over its future

Controversy erupted after Jeff Yass quietly bought up much of the village's commercial core. Yass is pictured alongside his wife Janine Coslett

Controversy erupted after Jeff Yass quietly bought up much of the village’s commercial core. Yass is pictured alongside his wife Janine Coslett

The redevelopment plans promises historic architecture, green space, and independent retailers - but no chains or hi-rise apartments

The redevelopment plans promises historic architecture, green space, and independent retailers – but no chains or hi-rise apartments

Those purchases include the former Gladwyne Market, the Village Shoppes, residential property on Youngs Ford Road, the Gladwyne Post Office building, and the former OMG Hair Salon, which was leased and later vacated.

Two longtime fixtures, the OMG Salon and Gladwyne Market, closed last year after the acquisitions sent ripples through the community fueling rumors about what was coming next.

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Gladwyne has long prized its small-town feel and locally owned businesses, even as it sits among some of the wealthiest ZIP codes in the state. 

The idea that one billionaire family now controls much of the village center has left some residents uneasy, particularly as redevelopment plans remained opaque until now.

‘There’s been a lot of justified, warranted concern,’ Golsorkhi acknowledged during the meeting, as reported by the Philadelphia Inquirer. 

Renderings presented by Haldon House show a carefully curated version of Gladwyne’s future: preserved late-1800s stone architecture, wraparound porches, ivy-covered walls, Adirondack chairs, hydrangeas, and signage branded ‘Gladwyne Square.’ 

The plan calls for new green space, pedestrian-friendly footpaths, and a mix of small, independent retailers.

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Golsorkhi stressed there would be no residential development, no national chain stores, and no high-rise buildings. 

The renderings emphasize Adirondack chairs, hydrangeas, and pedestrian-friendly walkways meant to evoke a timeless village square

The renderings emphasize Adirondack chairs, hydrangeas, and pedestrian-friendly walkways meant to evoke a timeless village square

Wide green lawns, picnic tables, and open gathering spaces feature prominently, projecting a calm, upscale community hub

Wide green lawns, picnic tables, and open gathering spaces feature prominently, projecting a calm, upscale community hub 

Gladwyne Pharmacy is slated to remain, with developers helping 'reimagine' its layout and customer experience

Gladwyne Pharmacy is slated to remain, with developers helping ‘reimagine’ its layout and customer experience

Gladwyne Market, a longtime community staple, was shuttered after its building was acquired by the developers

Gladwyne Market, a longtime community staple, was shuttered after its building was acquired by the developers

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Andre Golsorkhi, the CEO of Haldon House, has emerged as the public face of the project, insisting the billionaire-backed overhaul is a community-focused effort rooted in preservation rather than profit

Andre Golsorkhi, the CEO of Haldon House, has emerged as the public face of the project, insisting the billionaire-backed overhaul is a community-focused effort rooted in preservation rather than profit

Existing tenants like the local café Homeroom and Gladwyne Pharmacy would remain, while the former Gladwyne Market site would become a ‘casual, but elevated and approachable’ restaurant.

‘This is a place that we grew up, that we love, that we care for tremendously,’ Golsorkhi told those at the meeting. 

‘It has been protected for all the right reasons, but it has also not evolved. It needs a revitalization.’

Golsorkhi and his wife, Autumn Oser, co-owner of Haldon House, are both from the Gladwyne area, a point he emphasized repeatedly as residents questioned the motivations behind the project.

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But not everyone remains convinced. 

‘I just wonder what the end game is,’ one resident said during the question-and-answer session. 

‘There’s always a price for this, having someone come in and say, ‘I’m going to make your community really, really cool and don’t worry about the money.’

Golsorkhi said the Yass family is prepared to absorb the costs of redevelopment but that it was too early to project a timeline. 

He repeatedly described the effort as part investment, part philanthropy.

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The Gladwyne Post Office, also purchased as part of the redevelopment, has become a flashpoint after confusion over whether its services could eventually be reduced or relocated

The Gladwyne Post Office, also purchased as part of the redevelopment, has become a flashpoint after confusion over whether its services could eventually be reduced or relocated

OMG Hair Salon closed after its rent was sharply increased, becoming a flashpoint for critics of the project

OMG Hair Salon closed after its rent was sharply increased, becoming a flashpoint for critics of the project

Home Room café is expected to expand and remain part of the village’s future under the plan

Home Room café is expected to expand and remain part of the village’s future under the plan

They have already worked closely with Gladwyne Pharmacy helping ‘reimagine’ its design and customer experience with ‘no expectation of return.’

‘We’re doing that because we believe that the consistent experience and character of Gladwyne is really important,’ Golsorkhi said, adding that the pharmacy’s footprint had grown in ways that no longer best served the business or the community.

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The developers also floated ideas for expanding green space, adding picnic tables and lawns, and creating venues for community events. 

Independent bakeries, boutique fitness studios, and ice cream shops are among the businesses they hope to attract.

One flashpoint involved the Gladwyne Post Office, which Golsorkhi suggested was ‘retiring its services,’ raising the possibility of a consolidated shipping hub combining USPS, UPS, and FedEx.

But Paul Smith, manager of public affairs for the US Postal Service in the Philadelphia region, said the Gladwyne post office remains open for retail transactions, mailing services and that the post office itself is not closing.

Behind the polished renderings and talk of preservation, business owners say the transition has come at a personal cost.

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Other small shops around Youngs Ford and Righters Mill Roads now sit at the center of redevelopment uncertainty

Other small shops around Youngs Ford and Righters Mill Roads now sit at the center of redevelopment uncertainty

Gladwyne is prized by residents for its historic charm, tight-knit community, and small-village feel

Gladwyne is prized by residents for its historic charm, tight-knit community, and small-village feel

Longtime residents worry the village’s identity is being reshaped by one billionaire’s vision

Longtime residents worry the village’s identity is being reshaped by one billionaire’s vision

Maurice Tenenbaum, owner of OMG Hair Salon, said the building’s owners more than doubled his rent last fall, forcing him to give up the space.

Pete Liccio, the former owner of Gladwyne Market, said that he also felt pushed out after decades serving the community.

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Some residents left the meeting energized, calling the proposal long overdue.

‘What I’m seeing here is a center of gravity and an identity for Gladwyne that’s well-deserved and long been needed,’ one attendee said to the Inquirer.

Others walked away unconvinced, wary of a future shaped largely by one billionaire’s vision.

‘This is an investment and a philanthropic effort,’ Golsorkhi told the crowd. 

‘I understand and I recognize that that is a challenging thing to sort of believe.’

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Pennsylvania’s Deepest Inland Lake Is A Crystal-Clear Beauty East Of Pittsburgh For Camping And Fishing – Islands

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Pennsylvania’s Deepest Inland Lake Is A Crystal-Clear Beauty East Of Pittsburgh For Camping And Fishing – Islands






Pennsylvania is littered with more than 2,500 natural and manmade inland lakes. So when you find the deepest of these tucked among state forests 130 miles east of Pittsburgh, you’ve probably stumbled upon a gem. Raystown Lake’s rural location makes it one of Pennsylvania’s best-kept secrets, often overlooked for other lakes closer to the state’s cities and civilization. But those who commit to the three-hour drive are rewarded with 8,300 acres of tranquil and clear water that reaches a maximum depth of 200 feet. While it’s not as deep as Wazee, Wisconsin’s deepest inland lake and scuba diving gem, it still offers great fishing, swimming, boating, and other water sports.

Raystown Lake can thank Raystown Dam for its impressive depth, as this manmade reservoir only came to be when the Juniata River, just north, was dammed to control flooding. While natural lakes in Pennsylvania don’t exceed 85 feet in depth, Raystown’s significantly deeper and colder areas make it a better spot for anglers seeking deep-water fish species worthy of their trophy cabinets. These game fish range from striped bass (stripers) and trout to walleye and Atlantic salmon.

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Raystown Lake is also surrounded by over 21,000 acres of pristine forest covering the encircling Allegheny mountains in earthy greens and browns — a picturesque setting for a day on the water. The lake’s size and numerous fishing spots along its 118-mile shoreline also help it feel uncrowded when you’re sharing the water with other fishing boats, pontoons, kayaks, and houseboats. Fishing Booker recommends looking for the largest stripers in Raystown’s deepest sections, while largemouth and smallmouth bass can be caught in shallower spots. You can also reel in 20-pound trout during winter and fall when fishing depths beyond 80 feet. Trolling, jigging, and ice fishing are also all possible here during the year.

Peaceful camping at Pennsylvania’s Raystown Lake

After driving three hours here from Pittsburgh or 3.5 hours from Baltimore, no one expects you to turn around at the end of the day and drive all the way back. That’s why Raystown Lake has about 20 campgrounds for tents and RVs to choose from, as well as houseboats, glamping, B&Bs, hotels, and resorts. The campgrounds typically let you stay closest to the water and provide a serene setting to escape those everyday stressors for a while. They’re also generally more affordable.

If you love roughing it, Putt’s Camp is open year-round. This no-frills campground offers eight campsites for group bookings, including one waterfront spot. You also have a picnic shelter, fireplace, water pumps, and vault toilets. It’s close to state forest walking trails and a quiet section of the lake for swimming, fishing, and paddling. Seven Points Campground is another great option, especially for families and anglers wanting to catch largemouth and striped bass. Open from April to October, it has over 260 tent and RV sites, adjacent walking trails, and beach and marina access. Hot showers, electric and water hookups, playgrounds, a nearby grocery store, and picnic tables all make the camping experience much more comfortable.

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Raystown Lake is a year-round destination surrounded by natural scenery and charming towns, including Huntingdon, a picturesque Pennsylvania borough nestled along the Juniata River about 13 miles away. The borough also has the Lincoln Caverns, a small show cave where you can pan for real gems, in case you don’t have any luck fishing. Speaking of fishing, you’ll need to purchase a Pennsylvania fishing license online beforehand. And always stick to the state’s bag and size limits — it helps keep the lake well-stocked for everyone to enjoy.





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