Pennsylvania
How Patient Data Brings Life-Changing Medicine to Central Pennsylvania – UPMC & Pitt Health Sciences News Blog
Each year, thousands of patients visit UPMC hospitals, outpatient centers and specialty and primary care offices – generating thousands of datasets in the process. Whether it’s demographic information, imaging, lab results, signs and symptoms, family histories or treatment outcomes, there are countless stories for the masses of de-identified data to tell – and physicians like Hemal Gada, M.D., president, UPMC Heart and Vascular Institute in Central Pa., are using artificial intelligence to unravel those narratives.
“Applying machine learning and artificial intelligence to big datasets is a burgeoning field of medical research. In the next five years, we’ll use predictive modeling to precisely define the progression of diseases like cancer and heart disease,” Dr. Gada said.
Certain geographic, demographic, cultural, genetic and generational factors contribute to how diseases develop, progress and affect our bodies. For example, the social and environmental factors that drive the development and progression of heart disease will vary between someone living in rural Appalachia and someone living in an urban or suburban environment.
According to Dr. Gada, machine learning, a type of computer program, allows researchers to identify patterns in vast amounts of patient data. By identifying these trends in a specific subset of de-identified patient data from central Pennsylvania, Dr. Gada hopes to identify the precise factors that drive disease progression in the region – which could someday lead to specialized clinical trials and treatment approaches.
Dr. Gada and his colleagues published a study in The American Journal of Cardiology that utilized this machine learning approach to understand more about the characteristics of the stages of aortic stenosis for people living in central Pennsylvania. Patients with this condition have a heart valve that doesn’t open fully, which reduces blood flow from the heart to the aorta and to the rest of the body. If left untreated, chest pain and shortness of breath can develop, along with a host of other cardiac challenges – including clotting, heart failure, and stroke.
Historically, aortic stenosis patients have typically been assigned to three categories – mild, moderate, and severe. Severe patients typically undergo transcatheter aortic valve replacement (TAVR), but milder severity patients do not. Cardiologists have debated whether moderate aortic stenosis might benefit from a TAVR procedure due to their higher risk for poor outcomes.
Using echocardiograms and patient data from more than 61,000 aortic stenosis (AS) patients at UPMC Heart and Vascular Institute in Central Pa, Dr. Gada and his colleagues developed an algorithm to study the medical histories of these patients over time — How long after diagnosis before they were readmitted to the hospital? What other co-occurring diseases did they have? What signs did the body give to signal that a poor outcome or hospital readmission could be imminent?
The research team determined that moderate AS patients living in central Pennsylvania who have end-stage kidney disease or atrial fibrillation were at the highest risk for poor outcomes. According to Dr. Gada, these patients could need an intervention like the TAVR procedure, sooner rather than later.
While these findings are intriguing, Dr. Gada said this research is hypothesis-generating, meaning it will lead to the development of clinical trials – some of which are already underway.
Artificial intelligence-driven research often leads to more questions than it does answers, but the next time you’re at the doctor’s office and answering questions about your symptoms and health history, remember that you could shape the future of medicine simply by showing up and getting the care you need.
“Your data, which is de-identified in the research process, is just one piece of a much larger puzzle,” Dr. Gada said. “This data doesn’t have to be stagnant; it can help us develop personalized approaches to medicine in our community and determine what health challenges the citizens of our region face. We’re just beginning to scratch the surface of how artificial intelligence can transform health care in central Pennsylvania.”
Pennsylvania
Federal government sues Pennsylvania, others over SNAP data
(WHTM) — Pennsylvania is one of four states facing a lawsuit from the federal government over SNAP applicant data.
The U.S. Department of Justice filed suit against Pennsylvania, Kentucky, Michigan, and Minnesota. They are seeking the last five years of SNAP applicant data in the respective states.
The DOJ alleges that the four states refused to turn over data to the U.S. Department of Agriculture “so that USDA could ensure that states are properly administering and enforcing their determinations of residents’ eligibility.”
“The American people deserve a government that is transparent about how it spends their hard-earned tax dollars,” said Acting Attorney General Todd Blanche. “These four states are thwarting USDA’s efforts to ensure that the billions of dollars in SNAP benefits they distribute every year are not lost to fraud.”
“Stopping the rampant theft of taxpayer money demands a whole-of-government response, including strong participation at the state level,” said Assistant Attorney General Colin M. McDonald of the Justice Department’s National Fraud Enforcement Division. “These states are happy to take hundreds of millions of federal tax dollars—much of which is exploited by fraudsters—but want zero transparency over how those tax dollars are spent.”
The Department of Justice said 28 states promptly provided data and such indicated “there are billions of dollars per year in SNAP funds going to overpayments and fraud.”
The USDA has been seeking data for the past year or so, leading to a legal battle over concerns about how the data would be used.
Pennsylvania
House Republicans stall activity, Pennsylvania Rep. Meuser calls tactics ‘foolish’ | Fox Business Video
Maria Bartiromo reports on House Speaker Mike Johnson sending representatives home early as Republican hardliners stall floor activities, refusing votes without action on the SAVE America Act.
House Speaker Mike Johnson sent representatives home early as hardline Republicans stalled floor activities, demanding action on the SAVE America Act. President Donald Trump posted on Truth Social, urging House Republicans to unify and avoid giving power to Democrats. Rep. Dan Meuser (R-PA) labels the stalling tactics ‘foolish,’ emphasizing the need for legislative progress and appropriations.
Pennsylvania
Measles detected in two more counties in Pennsylvania as health department recommends early vaccination
Pennsylvania health officials have now detected measles cases in York and Northumberland Counties as cases in Lancaster County, the center of an ongoing outbreak, continued to rise.
And the state health department is now recommending early measles vaccinations for infants beginning at 6 months in affected areas in an effort to protect them against the spread of the highly contagious disease, which is particularly risky for young children. The same precautions should be taken by families with infants traveling to these areas.
Six Pennsylvania counties have now seen measles cases since an outbreak was first confirmed in Lebanon County in April. In all, the state has reported 81 measles cases across eight counties in 2026, more than five times the cases reported in 2025.
State health officials said it was too early to tell how the latest cases in York and Northumberland Counties are connected to others in the region, but that contact tracing investigations are continuing. All cases were among people who had not received at least two doses of the measles, mumps, and rubella (MMR) or whose vaccination status was unclear.
As of Wednesday, six cases had been confirmed in Northumberland County, to the north of Dauphin County, and one case had been detected in York County, along Lancaster’s western border.
Lebanon County has reported 20 cases and Dauphin and Berks Counties have reported two cases each.
Lancaster County has seen 38 cases of measles since late April, with health officials confirming seven cases in the last two weeks. The area was at the center of a prior measles outbreak in January, when state health officials confirmed eight cases in Lancaster County and an additional four between Chester and Montgomery Counties.
Vaccination rates among kindergarteners have decreased across Pennsylvania in recent years, and some counties affected in the current outbreak have particularly low rates, including Lancaster, where about 88.5% of kindergarten students are vaccinated. Health experts say that 95% of a community must be vaccinated to prevent the spread of the disease.
Health officials have been conducting contact tracing to detect as many cases as possible. In the current outbreak, they have twice warned Lancaster residents that they could have been exposed to measles.
Shoppers and employees at a local Kohl’s were potentially exposed to the virus over four days after a staffer tested positive in late May, LancasterOnline reported. And a person with measles visited the Lancaster County Courthouse on June 3.
But doctors in Lancaster County say they fear some measles cases are going unreported, either because patients don’t understand the importance of tracking measles cases or because they fear repercussions.
No cases have been confirmed in the Philadelphia region during this outbreak. But Delaware County health officials said last week that they had detected measles in two wastewater samples, indicating that someone with measles had used a bathroom connected to the county’s public water supply. It was unclear if that person lived in the county or was passing through.
Early vaccination recommended
On Wednesday, a statewide health alert urged physicians to accelerate vaccination schedules to protect children against measles. Officials had said they were considering the measure earlier this month as cases continued to rise.
Measles can infect nine in 10 unvaccinated people who are exposed to it, and can linger in the air for up to two hours and incubate in patients for three weeks. The disease typically presents with a fever and a rash but can cause brain inflammation and pneumonia in serious cases.
Typically, children receive the first of two MMR vaccines at 1 year old, then a second between 4 and 6 years old.
But children as young as 6 months can receive an additional “dose zero” to protect them from the disease amid an outbreak. In its alert, the state health department said parents should vaccinate infants between 6 and 11 months with the “dose zero” if they live in affected areas or if they’re planning to travel there.
Those children should then receive additional MMR doses at 12 to 15 months and 4 to 6 years.
This “dose zero” is less effective than doses given at 1 year old, officials cautioned. But it’s 58% effective against measles when given at 6 to 8 months, and 83% effective when administered at 9 to 11 months.
“Early MMR vaccination is safe and provides modest protection when measles is spreading,” officials wrote in the alert.
Children older than 12 months who haven’t been vaccinated should get an MMR dose immediately, and a second 28 days later, health officials said. Unvaccinated adults, or those without evidence of immunity, should also get two MMR doses.
And anyone who has received one dose of the MMR vaccine in the past should get a second at least 28 days after their first, officials said.
Usually, children who received a first dose at around 12 months wait to get their second dose until they’re 4 to 6 years old. But in an outbreak situation, those children should get their second doses early — at least 28 days after their first shot.
Adults born before 1957 are typically considered immune, but healthcare workers in that age group who don’t have lab evidence of immunity or prior infection should consider getting vaccinated, state officials said.
Adults who received an inactivated measles vaccine between 1963 and 1967 are considered unvaccinated during an outbreak, and should also get two doses of the current MMR vaccine.
Pregnant people, people with severely weakened immune systems, and people who have a history of experiencing severe allergic reactions, like anaphylaxis, to a vaccine ingredient or to a previous dose of MMR cannot receive the vaccine.
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