Sports
Sickle cell and football: Why the disease that mainly affects Black people needs more research
This article is part of The Athletic’s series marking UK Black History Month. To view the whole collection, click here.
Lassana Diarra was preparing for the 2010 World Cup in South Africa.
The midfielder, who had spells with Chelsea, Arsenal, and Portsmouth in the Premier League, was coming off the back of a difficult first season with Real Madrid. That campaign, 2009-10, he had made 30 appearances in all competitions for Manuel Pellegrini’s side as they finished second in La Liga, three points behind Barcelona. They had also crashed out of the Champions League at the last-16 stage against Lyon.
Keen to put an underwhelming club campaign behind him, Diarra, aged 25, joined up with the France squad — which included Thierry Henry, Franck Ribery, Hugo Lloris, Nicolas Anelka, and Karim Benzema — in a pre-tournament training camp. Tignes was the destination, chosen for its high altitude that would mimic conditions in South Africa.
However, on May 22, 2010, his hopes of playing on the world stage were dashed.
“Further to his intestinal pain contracted on the glacier in Tignes, check-ups have detected evidence of an unpredictable illness which justifies rest for an indeterminate period,” a statement from the France Football Federation read.
Diarra’s diagnosis was later confirmed as sickle cell anaemia.
Diarra playing for Real Madrid in 2010 (Elisa Estrada/Real Madrid via Getty Images)
The National Heart, Lung, and Blood Institute (NHLBI) defines sickle cell disease — the most common being called sickle cell anaemia — as a group of inherited disorders that affect haemoglobin (the major protein that carries oxygen in red blood cells). In sickle cell disease, red blood cells are misshaped, typically crescent- or “sickle”-shaped due to a gene mutation that affects the haemoglobin molecule. When red blood cells sickle, they do not bend or move easily and can block blood flow to the rest of the body.
Symptoms include painful episodes called sickle cell crises, an increased risk of serious infections and anaemia — where red blood cells cannot carry enough oxygen around the body — which can cause tiredness and a shortness in breath.
According to Healthline, a provider of healthcare information in the U.S., Black people are at a much higher risk of being affected by sickle cell disease. Researchers believe the reason lies in how this condition has evolved over time to protect against malaria — most common in sub-Saharan Africa, where sickle cell is prevalent. Having the sickle cell trait helps to reduce the severity of malaria.
The sickle cell trait is found in one in four west Africans and one in 10 Afro-Caribbeans. It is also found in people who originate from the Mediterranean, Asia, and the Middle East. It is less common in white Europeans.
Sickle cell disease and the sickle cell trait differ, as people with the trait carry only one copy of the altered haemoglobin gene and rarely have any clinical symptoms related to the disease, while people with the disease carry two copies.
The American Society of Hemotology say more than 100 million people worldwide have the sickle cell trait.
Despite how common the condition is and its sometimes fatal consequences, sickle cell is still a relatively unknown condition and its effect on sporting performance is lesser known still.
Part of the conclusion of ‘A Case Study of Two Premiership Footballers with Sickle Cell Trait’, a 2014 study conducted by the British Journal of Sports Medicine (BJSM), stated that “further research would be necessary with a larger cohort in order to further establish the relationship between redox homeostasis (defined as the maintenance of a balance between reducing and oxidizing reactions within a cell) and sickle cell trait in athletes”.
The BJSM did not respond to requests for comment from The Athletic.
Geno Atkins, a former defensive tackle for the NFL’s Cincinnati Bengals, spoke on his experience with the trait earlier this year. “I knew from my research that it would not be good for me to play in high altitude, so I prayed I wouldn’t get drafted by Denver, which is at a high altitude,” he told the Centers for Disease Control and Prevention (CDC). “I ended up in Cincinnati and have played at a very high level without any adverse effects of the sickle cell trait.”
He added: “Having the sickle cell trait does not exclude an athlete from participating in sports; however, the training staff and coaches need to take precautions to ensure the athlete is not put in dangerous situations.” In this case, Atkins cited an example of training in extreme heat.
Former Bengals defensive tackle Geno Atkins (Ian Johnson/Icon Sportswire via Getty Images)
Professional basketball player Billy Garrett Jr and former NFL running back Tiki Barber are two high-profile sportsmen with the disease, and wide receiver John Brown, most recently of the Buffalo Bills, possesses the trait.
Dr Mark Gillett, a consultant in sports and exercise medicine, tells The Athletic: “I’m not aware of it (sickle cell disease) in Premier League football or high-level football. I’ve not really seen it an awful lot at all. I am surprised that I haven’t. I would think that a player with full-blown sickle cell disease would find it difficult to compete at that level, just because of the physical demands of the game.
“At the same time, if you have sickle cell trait, you have that type of disease whereby extreme physical stress, altitude, or hydration can produce some symptoms. We may be seeing players with that and just not recognising it.
“Most Premier League football clubs are very diligent in the way they screen players. I think players at risk would have had their profiles done. If they have sickle cell trait, doctors would know about it. At the grassroots level, I suspect it happens a lot.”
Altitude was cited by Raymond Domenech, France’s national team manager at the time, when speaking about Diarra’s World Cup withdrawal in 2010.
“He wasn’t ready physically, he was really exhausted,” he said. “The illness was triggered by the altitude. He had predispositions that we couldn’t detect in advance. He needs a good 15 days of rest to fully recover, and he will recover, that’s for sure. It won’t have any bearing on the rest of his career but he’s not fit to play in a World Cup.” Diarra did not respond for comment when contacted by The Athletic.
Diarra, left, speaks with Domenech during France’s pre-2010 World Cup training camp (Franck Fife/AFP via Getty Images)
When asked how top-level teams would react to a player with the disease, Gillett says: “If they did find that when screening a player, obviously they would have to group that with the other things we look for when we assess players. We would have to speak to the player about it and make sure that their treatment is optimised.
“It would be a concern for players and clubs. Particularly when you get to the end of the season when the weather gets hotter and you’re more likely to be dehydrated. Sometimes, games have more riding on them and become more meaningful. It is certainly an added stress for them. It is hard enough being a Premier League footballer without having that to deal with as well. It would be a significant worry for them.”
The extent of Diarra’s illness was later confirmed by his club at the time, Real Madrid. In a statement, they said that Diarra was “now resting at home following medical advice due to asthenic syndrome secondary to a sickle cell anaemia that will be subjected to a hematological study (the study of blood and blood disorders) in Lyon Hospital”.
Valerie Davis, a haemoglobinopathy nurse counsellor at the Sickle Cell and Thalassemia support project in Wolverhampton, wants footballing authorities to increase their efforts in raising awareness and educate people within the game about the disease.
“There needs to be sessions whereby everybody is encouraged to be screened, irrespective of ethnicity,” she says. “Often it is thought that only specific ethnicities, such as those from African and Caribbean backgrounds can be impacted by this disease. The truth is anybody and everybody can be affected. Anyone who has haemoglobin and red blood cells can be impacted by sickle cell. It is the least likely for someone who is not from those backgrounds, but it can impact everybody.
“It could be a start to encourage everybody entering the sport to be screened. They then could do more work to bring in an expert to talk about the disease. Over the years, there has been a stigma around the disease and there shouldn’t be at all. This could help highlight the importance of screening. If someone is a carrier, they are normally absolutely fine. With rest, hydration, and nutrition, somebody can live an absolutely normal life.
“With a good lifestyle, it is a possibility that someone who is a carrier should have no issues going far in football. Even if they’re affected by the full-blown condition. I would encourage the football authorities to never reject someone based on them being a carrier of the sickle cell gene, but even with the full-blown condition with conditioning and support, it will not stop them from reaching the top.”
In 2022, former England international Emile Heskey discovered that two of his children had the sickle cell gene. He began giving blood and encouraging other Black donors to not only register but also be tested for the condition.
Emile Heskey revealed that two of his children have sickle cell trait (Mike Egerton/PA Images via Getty Images)
“We need a whole new generation of blood donors, especially people of Black heritage,” he told the Mirror. “Because they are more likely to donate better-matched blood to treat people with sickle cell disorder.
“Some patients with sickle cell rely on regular transfusions to stay alive. Giving blood is simple, easy and can save up to three lives.”
Davis shares Heskey’s sentiment in encouraging people to be tested for the disease.
“A lot of people do not know that they carry the sickle cell gene, perhaps until later,” she says. “A woman, for example, may only discover during pregnancy that she is a carrier of the gene.
“We are going all-out to educate people individually because sometimes people may know within their families that there may be a carrier but they often will deny they have it themselves. There is a stigma about the condition, so some people do not go and get screened for it.
“Unfortunately, partners decline screening and that is the sad case (that) very often we see the birth of children that are affected by sickle cell. There needs to be a lot more initiatives to highlight the importance of it. We need to explain ultimately what can happen if it is ignored.”
A treatment for sickle cell cure was approved by the Food and Drug Administration (FDA) in December 2023, with the therapy, called Casgevy, from Vertex Pharmaceuticals and CRISPR Therapeutics, becoming the first medicine to be approved in the United States. The same treatment was approved in the United Kingdom in November 2023, with experts calling it “a historic moment for the sickle cell community”.
However, in May 2024, the gene-editing sickle cell drug was not approved for National Health Service (NHS) use. The National Institute of Health and Care Excellence (NICE) did not recommend the gene therapy treatment, saying that it required “additional data” beyond the current proposal.
In September 2024, Pfizer voluntarily withdrew large amounts of the sickle cell disease treatment medication Voxelotor, sold under the brand name Oxbryta, from worldwide markets.
However, with stories like that of Diarra’s still sporadic within football, Davis believes the condition’s unpredictability means that conversations about sickle cell within the sport must continue.
“Like many conditions, there are varying degrees of the impact that it has on individuals but ultimately, it does limit because of the unpredictable nature of the condition, what very often people can do and when they can do it,” she says.
“Particularly in sport, and football, there is a lot of training and of course, a lot of commitment required to the sport. Somebody who is impacted or affected by sickle cell cannot always commit because they simply do not know when they will be affected. It is very hard to commit to a sport, especially football.”
Although progress has been made in the fight to find a cure to find a cure for the disease and raise awareness of the condition within sport, more needs to be done.
(Top photo: Franck Fife/AFP via Getty Images; design: Dan Goldfarb)
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Ali Haji-Sheikh and Shar Pourdanesh share the fact they are retired NFL players living beyond the glow of the NFL spotlight. But they also share another distinction tying them to current events: They are part of the Iranian diaspora hoping for the downfall of the Islamic revolution.
They make up part of a small group of men who played in the NFL – along with David Bakhtiari, his brother Eric Bakhtiari and T.J. Housmandzadeh – who are decedents of Iranians.
Washington Redskins kicker Ali Haji-Sheikh (6) talks to reporters at Jack Murphy Stadium during media day prior to Super Bowl XXII against the Denver Broncos. San Diego, California, on Jan. 26, 1988.(Darr Beiser/USA TODAY Sports)
Haji-Sheikh: Self-Determination For Iranians
Haji-Sheikh, 65, played in the 1980s for the New York Giants, Atlanta Falcons and Washington Redskins. He was a first-team All-Pro, made the Pro Bowl and was on the NFL All-Rookie team in 1983 for the Giants and, in his final season, won a Super Bowl XXII ring playing for the Washington Redskins and kicking six extra points in a 42-10 blowout of the Denver Broncos.
Now, Haji-Sheikh is the general manager at a Michigan Porsche-Audi dealership and is like the rest of us: Keeping up with world events when time permits.
Except the war the United States is currently waging against the Islamic Republic of Iran is kind of different because Haji-Sheikh’s dad emigrated from Iran to the United States in the 1950s and built a life here.
And his son would like to see freedom come to a country he’s never visited but has a kinship to.
“It’s a world event,” Haji-Sheikh said on Monday. “I am not a big fan of the Islamic revolution because I am not Islamic. I would like to see the people of Iran be able to determine their own future rather than it be determined by a few people. It would be nice to see them having a stable government where the people can actually decide how they want it to go.
Green Bay Packers kicker Al Del Greco (10) talks with New York Giants kicker Ali Haji-Sheikh (6) on Sept. 15, 1985, at Lambeau Field in Green Bay, Wisconsin. The Packers defeated the Giants 23-20.
Iranians Celebrating And Americans Protesting
Haji-Sheikh hasn’t taken to the streets of his native Michigan to celebrate a liberation that hasn’t fully manifested mere days after the American and Israeli bombing and elimination of the Ayatollah.
“I’m so far removed from that,” Haji-Sheikh said. “My mom is from Michigan and of Eastern European background. My dad is from Iran. But it’s like, he hasn’t been back since I was in eighth grade, so that’s a long time ago. That was when the Shah was still in power, mid-70s, ‘74 or ’75, because if he ever went back after that he never would have left. They would have held him, so there was no intention of going back.
“But if things change he might want to go, you never know.”
Despite being removed from any activism about what is happening in Iran Haji-Sheikh is an astute observer.
“My favorite thing I’m seeing right now on TV is the Iranians in America celebrating because there’s a chance, a glimpse, maybe a hope for freedom,” Haji-Sheikh said. “And you have these people in New York protesting. What are you protesting?”
Pourdanesh Thanks America, Israel
Pourdanesh retired from the NFL in 2000 after a seven-year career with the Redskins and Steelers. The six-foot-six and 312-pound offensive tackle was born in Tehran. He proudly tells people he was the NFL’s first Iranian-born player.
Pourdanesh is much more visible and open about his feelings about his country than others. And, bottom line, he loves that President Donald Trump is bombing the Islamic regime.
“This is a great day for all Iranians across the world,” Pourdanesh posted on his Instagram account on Saturday when the war began. “Thank you, President Trump, thank you to the nation of Israel. Thank you for everybody that has been standing up for my people, my brothers and sisters in Iran across the world. This is a great day.
“The infamous dictator is dead – the one person who has contributed to deaths of hundreds of thousands of Iranians and other people around the world, if not more. So, congratulations to my Iranian brothers and sisters. Now, go and take back the country.”
This message was not a one-off. Pourdanesh has been posting about what has been happening in Iran since January, when people in Iran took to the streets demanding liberty and the government’s thugs began killing them, with some estimates rising to 36,500 deaths.
Offensive lineman Shar Pourdanesh (68) of the Pittsburgh Steelers blocks against defensive lineman Jevon Kearse (90) of the Tennessee Titans during a game at Three Rivers Stadium on Sept. 24, 2000, in Pittsburgh. The Titans defeated the Steelers 23-20. (Photo by George Gojkovich/Getty Images)
‘Islam Does Not Represent The Iranian People’
“[The] Islamic Republic does not represent the Iranian people,” Pourdanesh said in another post. “Islam does not represent the Iranian people. For almost 50 years, the Iranian people and our country of Iran has been taken hostage by a terrorist regime, and it’s time to take that regime down.”
Pourdanesh was not available for comment on Monday. I did speak to a handful of other Iranian-Americans on Monday. They didn’t play in the NFL, but their opinions are no less valuable than those of former NFL players.
And these people, some of them participating in rallies on behalf of a free Iran, do not understand the thinking of some Americans and mainstream media.
One complained that media that reports on reparations for black Americans based on slavery in the 1800s dismisses the Islamic takeover of the American Embassy in 1979 as an old grievance.
Another said his brother lives in England, where Prime Minister Keir Starmer immediately called the American and Israeli attacks on the Ayatollah’s regime “illegal” but, as the head of the Crown Prosecution Service took years to do the same of Muslim rape (grooming) gangs in the country.
(Starmer announced a national “statutory inquiry” in June 2025).
Offensive lineman Shar Pourdanesh of the Washington Redskins looks on from the sideline during a game against the Pittsburgh Steelers at Three Rivers Stadium on Sept. 7, 1997, in Pittsburgh. The Steelers defeated the Redskins 14-13. (Photo by George Gojkovich/Getty Images)
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Pourdanesh Calls Out NFL Silence
And finally, Pourdanesh put the NFL on blast. He said in yet another post that during his career, the NFL asked him to honor black history, asked him to stand for women’s rights, asked him to fight for equality for those who cannot defend themselves.
“I did everything they asked, and now I ask the NFL this: Where are you now? Why haven’t we heard a single word out of the NFL? NFL, Commissioner Roger Goodell, all the NFL teams out there, all the players who say they stand for social justice, where are you now?
“Why haven’t we heard a single word out of you with regard to the people who have been killed as of today? The very values you claim to espouse are being trampled right now. Why haven’t we heard a single word?”
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The day after he saved the Dodgers’ season, Will Klein was hungry. He ordered from Mod Pizza.
He drove over to pick up his order. The guy that handed him the pizza told him he looked just like Will Klein.
“You should just look at the name on the order,” Klein told him.
Chaos ensued.
“He actually started screaming,” Klein said. “He just started flipping out, which was funny.”
Thing is, if it were two days earlier, the guy would have had no idea what Klein looked like. Neither would you.
On Oct. 26, Klein was the last man in the Dodgers’ bullpen, a wild thing on his fourth organization in two years, a last-minute addition to the World Series roster.
On Oct. 27, the Dodgers played 18 innings, and the last man in the Dodgers’ bullpen delivered the game of his life: four shutout innings, holding the Toronto Blue Jays at bay until Freddie Freeman hit a walk-off home run.
Dodgers pitcher Will Klein celebrates during the 16th inning of Game 3 of the World Series against the Toronto Blue Jays at Dodger Stadium on Oct. 27.
(Mark J. Terrill / Associated Press)
When Klein returned to the clubhouse, Sandy Koufax walked over to shake hands and congratulate him.
That was Game 3 of the World Series. The Dodgers, the significantly older team, slogged through the next two games, batting .164 and losing both.
If not for Klein, that would have been the end. The Blue Jays would have won the series in five games, and there would have been no Kiké Hernández launching a game-ending double play on the run in Game 6, no Miguel Rojas tying home run and game-saving throw in Game 7, no Andy Pages game-saving catch and Will Smith winning home run in Game 7, no Yoshinobu Yamamoto winning Game 6 as a starter and Game 7 as a reliever.
There would have been no parade.
When Klein rescued the Dodgers, he had pitched one inning in the previous 30 days.
“You can never take your mind out of it,” he said. “You’ve got to stay prepared. Something might come up, and you don’t want to be the guy that gets thrown in the fire and just burns.”
The Dodgers are not shy about grabbing a minor league pitcher, telling him what he can do better and what he should stop doing, and seeing what sticks. If nothing sticks, the Dodgers are also not shy about spitting out the pitcher and designating him for assignment.
In his minor league career, Klein struck out 13 batters every nine innings, which is tremendous. He walked seven batters every nine innings, which is hideous.
The Dodgers scrapped his slider, mixed in a sweeper, and told him his arm was so good that he should stop trying to make perfect pitches and just let fly.
“A lot of times, pitchers are guilty of giving hitters too much credit, and hitters are guilty of giving pitchers too much credit,” said Andrew Friedman, the Dodgers’ president of baseball operations.
“Part of our job is to show them information that helps instill some confidence. I think that really landed with Will.”
In his four September appearances with the Dodgers — after a minor-league stint to apply the team’s advice — he faced 17 batters, walked one, and did not give up a run. That’s why he isn’t buying the suggestion that something suddenly clicked in the World Series.
“Things were incrementally getting better,” he said, “and then you add that to the atmosphere. It amplifies it to 100. All the prep work and mental stuff that I had been doing, I finally got a chance to shine.”
Said Dodgers manager Dave Roberts: “He’s done it in the highest of leverage. You can’t manufacture that. You’ve got to live it and do it. So, since he’s done it, I think he’s got a real confidence.”
Dodgers pitcher Will Klein speaks during DodgerFest at Dodger Stadium on Jan. 31.
(John McCoy / Getty Images)
Klein last started a game three years ago, at triple A. After making 72 pitches in those four innings of Game 3, did he entertain the thought that maybe, just maybe, he was meant to be a starter after all?
“No,” he said abruptly. “I hate waiting four or five days to pitch and knowing exactly when I’m going to pitch.
“When I did, the anxiety just built. I want to go pitch. I hate sitting there and waiting. That kind of eats at you. I like being able to go out to the bullpen and have a chance to pitch every day.”
The Dodgers are so deep that Klein might not make the team out of spring training. Whatever happens, he’ll always have Game 3.
In the wake of that game, a fan wanted to buy a Klein jersey but could not find one. So the fan made one himself before Game 4, using white electrical tape on the back of a Dodger blue jersey. I showed Klein a picture.
“That’s cool,” Klein said. “That’s pretty funny.”
Dave Wong, a Dodgers fan living in San Francisco Giants territory, also wanted to buy a Klein jersey.
“They didn’t have a jersey for him,” Wong said.
He settled for the Dodger blue T-shirt he found online and wore it to last Friday’s Cactus League game against the Giants, with these words in white letters: “Will Klein Appreciation Shirt.”
This, then, would be a Will Klein Appreciation Column.
Sports
NBA player calls for Hawks to cancel their ‘Magic City’ strip club promotional night out of respect for women
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An NBA player has taken exception to an Atlanta Hawks promotional night, which is a nod to a famed strip club in the city.
The Hawks have “Magic City Night” scheduled for March 16 against the Orlando Magic, but a player for neither team isn’t too fond of paying tribute to a strip club, which has been famed for its late-night stories involving athletes, celebrities and more.
While the Hawks call it an ode to a “cultural institution,” San Antonio Spurs center Luke Kornet shared his displeasure in a letter posted on Medium.
Luke Kornet of the San Antonio Spurs reaches for the ball during the third quarter against the Brooklyn Nets at Barclays Center on Feb. 26, 2026 in the Brooklyn borough of New York City. (Ishika Samant/Getty Images)
Kornet, a nine-year veteran and 2024 NBA champion with the Boston Celtics, called for the Hawks’ promotional night to be canceled later this month, saying that it is disrespectful to women to honor the strip club.
“In its press release, the Hawks failed to acknowledge that this place is, as the business itself boasts, “Atlanta’s premier strip club.” Given this fact, I would like to respectfully ask that the Atlanta Hawks cancel this promotional night with Magic City,” Kornet wrote in his post.
“The NBA should desire to protect and esteem women, many of whom work diligently every day to make this the best basketball league in the world. We should promote an atmosphere that is protective and respectful of the daughters, wives, sisters, mothers, and partners that we know and love.”
The Hawks boasted about the theme night in its press release, including a live performance by famous Atlanta rapper T.I., a co-branded, limited-edition hoodie and even the establishment’s “World Famous” lemon-pepper chicken wings in the arena.
A general view of signage with the State Farm Arena logo on Nov. 14, 2025, outside State Farm Arena, in Atlanta, GA. (Erica Denhoff/Icon Sportswire)
“This collaboration and theme night is very meaningful to me after all the work that we did to put together ’Magic City: An American Fantasy’,” said Hawks principal owner, filmmaker and actor, Jami Gertz, said in a press release. “The iconic Atlanta institution has made such an incredible impact on our city and its unique culture.”
Kornet wrote that allowing the night to continue “without protest would reflect poorly on us as an NBA community, “specifically in being complicit in the potential objectification and mistreatment of women in our society.”
Kornet wrote that “others throughout the league” were surprised by the Hawks’ decision to have this promotional night.
“We desire to provide an environment where fans of all ages can safely come and enjoy the game of basketball and where we can celebrate the history and culture of communities in good conscience. The celebration of a strip club is not conduct aligned with that vision,” he wrote.
Luke Kornet of the San Antonio Spurs defends against the Charlotte Hornets during their game at Spectrum Center on Jan. 31, 2026 in Charlotte, North Carolina. (Jacob Kupferman/Getty Images)
The Hawks have seen good reception for the promotional night, as Tick Pick reported a get-in price was initially $10 for the game and has since skyrocketed to $94.
Kornet is in his first season with the Spurs, his sixth NBA team, where he has played mainly in a bench role. He averages 7.1 points and 6.5 rebounds per game across 50 contests.
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