Science
L.A. child dies from complication of measles infection contracted in infancy
A school-age child in Los Angeles County has died from a rare complication of measles after contracting the disease in infancy, the county public health department announced Thursday.
The child — who was not old enough to be vaccinated at the time of infection — died from subacute sclerosing panencephalitis, a fatal progressive brain disorder that strikes roughly 1 in 10,000 people infected with measles in the U.S. Doctors believe the risk is as high as 1 in every 600 children who contract measles as a baby.
The disorder typically develops two to 10 years after initial infection, even when — as in this child’s case — the patient recovers fully from measles. The disease begins with seizures, cognitive decline and involuntary muscle spasms, and progresses to dementia, coma and eventually death.
“Most pediatricians in the U.S. have never seen a child with SSPE because we’ve been vaccinating kids against measles for decades,” said Dr. Adam Ratner, a New York-based pediatric infectious-disease specialist and author of the book, “Booster Shots: The Urgent Lessons of Measles and the Uncertain Future of Children’s Health.”
The Los Angeles County Department of Public Health could not release further details on the child’s age, gender or location due to patient privacy laws, a spokesperson said.
The department could only confirm that the child acquired measles before becoming eligible for an MMR vaccination.
“This case is a painful reminder of how dangerous measles can be, especially for our most vulnerable community members,” county health officer Dr. Muntu Davis said in a statement. “Infants too young to be vaccinated rely on all of us to help protect them through community immunity.”
Children typically receive their first MMR dose when they are 12 to 15 months old and a second dose between the ages of 4 and 6 years.
An early first dose from the age of 6 to 11 months is recommended for babies traveling internationally or through an international hub. Infants under the age of 6 months are too young to receive the MMR shot, according to guidelines from the U.S. Centers for Disease Control and Prevention.
Very young babies rely on antibodies acquired during gestation and herd immunity to protect them from measles, which killed roughly 400 children every year in the U.S. before the introduction of the combined MMR vaccine in 1971.
Measles was “eliminated” in the U.S. in 2000, meaning the disease was rare enough and immunity widespread enough to prevent local transmission if an errant case popped up.
For 25 years, parents in the U.S. have been able to trust that herd immunity will keep infants safe from measles until they are old enough to be vaccinated.
This recent death may be a signal that social contract is beginning to break.
Childhood immunization rates have been slowly but steadily falling nationwide, from 95% in the years before the COVID pandemic to below 93% in the 2023-24 school year.
In California, one of five U.S. states that banned all non-medical vaccine exemptions, the vaccination rate that year was 96.2%. California is also one of only 10 states with a kindergarten measles vaccination rate exceeding the 95% threshold experts say is necessary to achieve herd immunity.
But if current vaccination rates hold steady over the coming decades, measles will once again be endemic in the U.S. within 25 years, two Stanford University researchers found in a study published earlier this year.
“Right now we should really be trying to up vaccination rates,” Mathew Kiang, an assistant professor of epidemiology and population health, told The Times in April. “If we just kept them the way they are, bad things are going to happen within about two decades.”
Times staff writer Jenny Gold contributed to this report.
Science
What’s in a Name? For These Snails, Legal Protection
The sun had barely risen over the Pacific Ocean when a small motorboat carrying a team of Indigenous artisans and Mexican biologists dropped anchor in a rocky cove near Bahías de Huatulco.
Mauro Habacuc Avendaño Luis, one of the craftsmen, was the first to wade to shore. With an agility belying his age, he struck out over the boulders exposed by low tide. Crouching on a slippery ledge pounded by surf, he reached inside a crevice between two rocks. There, lodged among the urchins, was a snail with a knobby gray shell the size of a walnut. The sight might not dazzle tourists who travel here to see humpback whales, but for Mr. Avendaño, 85, these drab little mollusks represent a way of life.
Marine snails in the genus Plicopurpura are sacred to the Mixtec people of Pinotepa de Don Luis, a small town in southwestern Oaxaca. Men like Mr. Avendaño have been sustainably “milking” them for radiant purple dye for at least 1,500 years. The color suffuses Mixtec textiles and spiritual beliefs. Called tixinda, it symbolizes fertility and death, as well as mythic ties between lunar cycles, women and the sea.
The future of these traditions — and the fate of the snails — are uncertain. The mollusks are subject to intense poaching pressure despite federal protections intended to protect them. Fishermen break them (and the other mollusks they eat) open and sell the meat to local restaurants. Tourists who comb the beaches pluck snails off the rocks and toss them aside.
A severe earthquake in 2020 thrust formerly submerged parts of their habitat above sea level, fatally tossing other mollusks in the snail’s food web to the air, and making once inaccessible places more available to poachers.
Decades ago, dense clusters of snails the size of doorknobs were easy to find, according to Mr. Avendaño. “Full of snails,” he said, sweeping a calloused, violet-stained hand across the coves. Now, most of the snails he finds are small, just over an inch, and yield only a few milliliters of dye.
Science
Video: This Parrot Has No Beak, But Is at the Top of the Pecking Order
new video loaded: This Parrot Has No Beak, But Is at the Top of the Pecking Order
By Meg Felling and Carl Zimmer
April 20, 2026
Science
Contributor: Focus on the real causes of the shortage in hormone treatments
For months now, menopausal women across the U.S. have been unable to fill prescriptions for the estradiol patch, a long-established and safe hormone treatment. The news media has whipped up a frenzy over this scarcity, warning of a long-lasting nationwide shortage. The problem is real — but the explanations in the media coverage miss the mark. Real solutions depend on an accurate understanding of the causes.
Reporters, pharmaceutical companies and even some doctors have blamed women for causing the shortage, saying they were inspired by a “menopause moment” that has driven unprecedented demand. Such framing does a dangerous disservice to essential health advocacy.
In this narrative, there has been unprecedented demand, and it is explained in part by the Food and Drug Administration’s recent removal of the “black-box warning” from estradiol patches’ packaging. That inaccurate (and, quite frankly, terrifying) label had been required since a 2002 announcement overstated the link between certain menopause hormone treatments and breast cancer. Right-sizing and rewording the warning was long overdue. But the trouble with this narrative is that even after the black-box warning was removed, there has not been unprecedented demand.
Around 40% of menopausal women were prescribed hormone treatments in some form before the 2002 announcement. Use plummeted in its aftermath, dipping to less than 5% in 2020 and just 1.8% in 2024. According to the most recent data, the number has now settled back at the 5% mark. Unprecedented? Hardly. Modest at best.
Nor is estradiol a new or complex drug; the patch formulation has existed for decades, and generic versions are widely manufactured. There is no exotic ingredient, no rare supply chain dependency, no fluke that explains why women are suddenly being told their pharmacy is out of stock month after month.
The story is far more an indictment of the broken insurance industry: market concentration, perverse incentives and the consequences of allowing insurance companies to own the pharmacy benefit managers that effectively control drug access for the majority of users. Three companies — CVS Caremark, Express Scripts and OptumRx — manage 79% of all prescription drug claims in the United States. Those companies are wholly owned subsidiaries of three insurance behemoths: CVS Health, Cigna and UnitedHealth Group, respectively. This means that the same corporation that sells you your insurance plan also decides which drugs get covered, at what price, and whether your pharmacy can stock them. This is called vertical integration. In another era, we might have called it a cartel. The resulting problems are not unique to hormone treatments; they have affected widely used medications including blood thinners, inhalers and antibiotics. When a low-cost generic such as estradiol — a medication with no blockbuster profit margins and no patent protection — runs into friction in this system, the friction is not random. It is structural. Every decision in that chain is filtered through the same corporate profit motive. And when the drug in question is an off-patent estradiol patch that has negligible profit margins because of generic competition but requires logistical investment to keep consistently in stock? The math on “how much does this company care about ensuring access” is not complicated.
Unfortunately, there is little financial incentive to ensure smooth, consistent access. There is, however, significant financial incentive to steer patients toward branded alternatives, or simply to let supply tighten — because the companies aren’t losing much profit if sales of that product dwindle. This is not a conspiracy theory: The Federal Trade Commission noted this dynamic in a report that documented how pharmacy benefit managers’ practices inflate costs, reduce competition and harm patient access, particularly for independent pharmacies and for generic drugs.
Any claim that the estradiol patch shortage is meaningfully caused by more women now demanding hormone treatments is a distraction. It is also misogyny, pure and simple, to imply that the solution to the shortage is for women’s health advocates to dial it down and for women to temper their expectations. The scarcity of estradiol patches is the outcome of a broken system refusing to provide adequate supply.
Meanwhile, there are a few strategies to cope.
- Ask your prescriber about alternatives. Estradiol is available in multiple formulations, including gel, spray, cream, oral tablet, vaginal ring and weekly transdermal patch, which is a different product from the twice-weekly patch and may be more consistently available depending on manufacturer and region.
- Consider an online pharmacy. Many are doing a good job locating and filling these prescriptions from outside the pharmacy benefit manager system.
- Call ahead. Patch shortages are inconsistent across regions and distributors. A call to pharmacies in your area, or a broader geographic radius if you’re able, can locate stock that your regular pharmacy doesn’t have.
- Consider a compounding pharmacy. These sources can sometimes meet needs when commercially manufactured products are inaccessible. The hormones used are the same FDA-regulated bulk ingredients.
Beyond those Band-Aid solutions, more Americans need to fight for systemic change. The FTC report exists because Congress asked for it and committed to legislation that will address at least some of the problems. The FDA took action to change the labeling on estrogen in the face of citizen and medical experts’ pressure; it should do more now to demand transparency from patch manufacturers.
Most importantly, it is on all of us to call out the cracks in the current system. Instead of repeating “there’s a patch shortage” or a “surge in demand,” say that a shockingly small minority of menopausal women still even get hormonal treatments prescribed at all, and three drug companies control the vast majority of claims in this country. Those are the real problems that need real solutions.
Jennifer Weiss-Wolf, the executive director of the Birnbaum Women’s Leadership Center at New York University School of Law, is the author of the forthcoming book “When in Menopause: A User’s Manual & Citizen’s Guide.” Suzanne Gilberg, an obstetrician and gynecologist in Los Angeles, is the author of “Menopause Bootcamp.”
-
New York1 hour agoN.Y.P.D. Narcotics Unit Under Review After a Beating Is Caught on Tape
-
Detroit, MI2 hours agoMI Healthy Climate Conference in Detroit focuses on green funding and strong future
-
San Francisco, CA2 hours agoCalifornia’s New Hotel Edit: The Best Places to Stay Across the Golden State in 2026
-
Dallas, TX2 hours agoThe Brandon Aubrey Deal | DZTV
-
Miami, FL2 hours agoRanking the Miami Heat’s Top Trade Targets
-
Boston, MA2 hours agoFormer Massachusetts doctor faces 81 new sexual assault charges
-
Denver, CO2 hours agoHouston County murder suspect returns to face charges after her arrest in Denver
-
Seattle, WA2 hours agoWest Seattle Tool Library to host annual tool sale this Saturday, April 25 | The White Center Blog