Science
‘Grief into action.’ Philanthropists give historic $150 million donation to City of Hope for pancreatic cancer research
For entrepreneur and philanthropist Emmet Stephenson Jr., seeing his wife and friends die from pancreatic cancer served as a wake-up call.
His wife, Toni, a patient at Duarte, Calif.-based cancer center City of Hope, died at 74 after a four-month battle with pancreatic cancer.
Now Emmet and his daughter Tessa are donating a historic $150 million to the City of Hope to help advance research into finding a cure for what’s known as the “silent killer.”
“We decided we were going to turn our grief into action and we wanted as few people as possible to go through what we did,” said Tessa Stephenson Brand. “It was fast. It was painful.”
The donation is the largest single gift the City of Hope has ever received, surpassing the $100 million Panda Express founders Andrew and Peggy Cherng gave to the nonprofit last year.
World-renowned geneticist and diabetes expert Dr. Arthur Riggs also donated $100 million in 2021 to his longtime employer City of Hope before he passed away from a battle with a type of blood cancer known as lymphoma.
To help fuel the development of treatment and cures for pancreatic cancer, the Stephensons’ donation will help fund a $1 million prize that will be awarded annually (beginning in 2025) to a scientist or team that’s leading innovation in this field.
Pancreatic cancer research is underfunded and the City of Hope is trying to find new ways to cut down on bureaucracy so researchers and scientists can make progress at a faster rate, said Robert Stone, the chief executive of City of Hope. The gift equals nearly two-thirds of the total annual research budget for pancreatic cancer from the National Cancer Institute, City of Hope said in a news release about the donation.
“We’re trying to leapfrog and bring new ideas to challenge how research has been done traditionally,” Stone said.
Emmet Stephenson said the donation, which is expected to be spread out over 10 years, will also help fund grants, an annual symposium and a facility that collects tissues, blood and other materials needed for pancreatic cancer research.
“If we were to get lucky and find a cure for pancreatic cancer soon, then we’re happy to have the money go to the next most deadly disease in the cancer arena,” he said. Stephenson is the retired co-founder and chairman of tech company StarTek .
Pancreatic cancer is the third-leading cause of cancer death in the United States, according to the National Cancer Institute. In 2024, about 66,440 people nationwide will be diagnosed with pancreatic cancer and 51,750 people will die from this disease, according to estimates from The American Cancer Society.
Located behind the stomach, the pancreas is a large gland that helps people digest food and regulate blood sugar. Pancreatic cancer occurs when abnormal cells in the gland multiply, forming a tumor.
Dr. Daniel D. Von Hoff, a professor and cancer scientist at the Translational Genomics Research Institute in Phoenix, that is a part of the City of Hope, said pancreatic cancer is hard to detect early partly because the pancreas is tough to image and people often don’t show symptoms.
Some of the risk factors include smoking, obesity, alcohol and diabetes that can cause inflammation in the body. Pancreatic cancer is also on track to become the second-leading cause of cancer-related deaths before 2030 as the population ages. It’s most frequently diagnosed in people between the ages of 65 to 74, according to the National Cancer Institute.
Known as the “silent killer,” people often don’t show symptoms, which includes fatigue, belly pain and a loss appetite, before the cancer cells have multiplied.
“It’s like a toothache many people describe and so it’s kind of throbbing,” Von Hoff said. “By that time, it’s probably too late.”
Genetic testing, especially if you have a history of cancer in your family, could help detect a tumor early. Still, it’s possible to get pancreatic cancer at a young age.
Toni Bravo, a 21-year-old student who grew up in Tarzana, said she went to the emergency room last year because she was experiencing anxiety. After she got a CT scan, doctors in Indiana found a rare tumor on her pancreas. She became a patient at the City of Hope where she underwent surgery to remove the tumor from her pancreas.
The scariest part, she said, was she didn’t really have any symptoms or a history of pancreatic cancer.
As a pancreatic cancer survivor, Bravo isn’t letting the diagnosis define her life and urges people to listen to their bodies.
“The journey is hard,” she said. “Having the love of others makes it easier…and having that mental strength makes the journey possible.”
Science
Lyrids Meteor Shower: How to Watch, Peak Time and Weather Forecast
Our universe might be chock-full of cosmic wonder, but you can observe only a fraction of astronomical phenomena with the naked eye. Meteor showers, natural fireworks that streak brightly across the night sky, are one of them.
The latest observable meteor shower will be the Lyrids, which has been active since April 14 and is forecast to continue through April 30. The shower reaches its peak April 21 to 22, or Tuesday night into Wednesday morning.
According to NASA, the Lyrids are one of the oldest known meteor showers, and have been enjoyed by stargazers for nearly 3,000 years. Their bright, speedy streaks are caused by the dusty debris from a comet named Thatcher. They appear to spring from the constellation Lyra, which right now can be seen in the eastern sky at night in the Northern Hemisphere.
The moon will be about 27 percent full tonight, appearing as a thick crescent in the sky, according to the American Meteor Society.
To get a hint at when to best watch for the Lyrids, you can use this tool, which relies on data from the Global Meteor Network. It shows fireball activity levels in real time.
And while you gaze at the heavens, keep an eye out for other stray meteors streaking across the night sky. Skywatchers are reporting that the amount of fireballs is double what is usually seen by this point in the year.
Where meteor showers come from
There is a chance you might see a meteor on any given night, but you are most likely to catch one during a shower. Meteor showers are caused by Earth passing through the rubble trailing a comet or asteroid as it swings around the sun. This debris, which can be as small as a grain of sand, leaves behind a glowing stream of light as it burns up in Earth’s atmosphere.
Meteor showers occur around the same time every year and can last for days or weeks. But there is only a small window when each shower is at its peak, which happens when Earth reaches the densest part of the cosmic debris. The peak is the best time to look for a shower. From our point of view on Earth, the meteors will appear to come from the same point in the sky.
The Perseid meteor shower, for example, peaks in mid-August from the constellation Perseus. The Geminids, which occur every December, radiate from the constellation Gemini.
How to watch a meteor shower
Michelle Nichols, the director of public observing at the Adler Planetarium in Chicago, recommends forgoing the use of telescopes or binoculars while watching a meteor shower.
“You just need your eyes and, ideally, a dark sky,” she said.
That’s because meteors can shoot across large swaths of the sky, so observing equipment can limit your field of view.
Some showers are strong enough to produce up to 100 streaks an hour, according to the American Meteor Society, though you probably won’t see that many.
“Almost everybody is under a light-polluted sky,” Ms. Nichols said. “You may think you’re under a dark sky, but in reality, even in a small town, you can have bright lights nearby.”
Planetariums, local astronomy clubs or even maps like this one can help you figure out where to go to escape excessive light. The best conditions for catching a meteor shower are a clear sky with no moon or cloud cover, sometime between midnight and sunrise. (Moonlight affects visibility in the same way as light pollution, washing out fainter sources of light in the sky.) Make sure to give your eyes at least 30 minutes to adjust to seeing in the dark.
Ms. Nichols also recommends wearing layers, even during the summer. “You’re going to be sitting there for quite a while, watching,” she said. “It’s going to get chilly, even in August.”
Bring a cup of cocoa or tea for even more warmth. Then lie back, scan the sky and enjoy the show.
Where weather is least likely to affect your view
Storm systems sweep across the country in early spring, and some will be obscuring skies tonight. But there will still be plenty of areas with clear skies, particularly in parts of the central United States.
“The best spot is going to be in the Upper Midwest,” said Rich Bann, a meteorologist with the Weather Prediction Center.
Minnesota, Wisconsin and Iowa will offer especially good sky-viewing weather and a beach on the Great Lakes could be a nice spot to look up at the stars.
But don’t expect to view the show from Chicago, as Illinois could see some thunderstorms. The weather will be better in the Northern and Central Plains, particularly the eastern Dakotas.
High, wispy clouds are expected over the Ohio and Tennessee Valleys and into parts of the Mid-Atlantic. But, Mr. Bann said, “you may be able to see some shooting stars through thin clouds.”
Clouds will be draped across much of the Southeast and the Northeast, though there could be some clearing in Florida, Georgia, the Carolinas and Virginia. Remember, the meteors could be visible all night long. If you look outside and see clouds, try again later.
Catching the spectacle will be challenging across much of the West, particularly from Washington into Northern California, where a storm system is bringing rain and snow. That system will move east overnight.
There are likely to be some pockets of clear skies at times across southern Nevada, northwest Arizona and southwest Utah, Mr. Bann said.
Amy Graff contributed reporting.
Science
FBI probes cases of missing or dead scientists, including four from the L.A. area
WASHINGTON — Amid growing national security concerns, the FBI said Tuesday that it has launched a broad investigation in the deaths or disappearances of at least 10 scientists and staff connected to highly sensitive research, including four from the Los Angeles area.
“The FBI is spearheading the effort to look for connections into the missing and deceased scientists. We are working with the Department of Energy, Department of War, and with our state and state and local law enforcement partners to find answers,” the agency said in a statement.
The FBI’s announcement comes after the House Oversight Committee announced that it would investigate reports of the disappearance and deaths of the scientists, sending letters seeking information from the agencies involved in the federal inquiry as well as NASA, which owns the Jet Propulsion Laboratory in La Cañada Flintridge, where three of the missing or dead scientists worked.
“If the reports are accurate, these deaths and disappearances may represent a grave threat to U.S. national security and to U.S. personnel with access to scientific secrets,” Reps. James Comer (R-Ky.), chairman of the committee, and Eric Burlison (R-Mo.) wrote in the letters.
President Trump told reporters last week that he had been briefed on the missing and dead scientists, which he described as “pretty serious stuff.” He said at the time that he expected answers on whether the deaths were connected “in the next week and a half.”
Michael David Hicks, who studied comets and asteroids at JPL, was the first of the scientists who disappeared or died. He died on July 30, 2023, at the age of 59. No cause of death was disclosed.
A year later, JPL physicist Frank Maiwald died at 61, with no cause of death disclosed.
Two other Los Angeles scientists are part of the string of deaths and disappearances.
On June 22, 2025, Monica Jacinto Reza, a materials scientist at JPL, disappeared while on a hike near Mt. Waterman in the San Gabriel Mountains.
On Feb. 16, Caltech astrophysicist Carl Grillmair was fatally shot on the porch of his Llano home. The Los Angeles County Sheriff’s department arrested Freddy Snyder, 29, in connection with the shooting. Snyder had been arrested in December on suspicion of trespassing on Grillmair’s property.
Snyder has been charged with murder.
There is no evidence at this point that the deaths and disappearances, which occurred over a span of four years, are connected.
A spokesperson for NASA, which owns JPL, said in a statement on X that the agency is “coordinating and cooperating with the relevant agencies in relation to the missing scientists.
“At this time, nothing related to NASA indicates a national security threat,” agency spokesperson Bethany Stevens wrote. “The agency is committed to transparency and will provide more information as able.”
Representatives from Caltech, which manages JPL, did not immediately respond to a request for comment.
Science
What’s in a Name? For These Snails, Legal Protection
The sun had barely risen over the Pacific Ocean when a small motorboat carrying a team of Indigenous artisans and Mexican biologists dropped anchor in a rocky cove near Bahías de Huatulco.
Mauro Habacuc Avendaño Luis, one of the craftsmen, was the first to wade to shore. With an agility belying his age, he struck out over the boulders exposed by low tide. Crouching on a slippery ledge pounded by surf, he reached inside a crevice between two rocks. There, lodged among the urchins, was a snail with a knobby gray shell the size of a walnut. The sight might not dazzle tourists who travel here to see humpback whales, but for Mr. Avendaño, 85, these drab little mollusks represent a way of life.
Marine snails in the genus Plicopurpura are sacred to the Mixtec people of Pinotepa de Don Luis, a small town in southwestern Oaxaca. Men like Mr. Avendaño have been sustainably “milking” them for radiant purple dye for at least 1,500 years. The color suffuses Mixtec textiles and spiritual beliefs. Called tixinda, it symbolizes fertility and death, as well as mythic ties between lunar cycles, women and the sea.
The future of these traditions — and the fate of the snails — are uncertain. The mollusks are subject to intense poaching pressure despite federal protections intended to protect them. Fishermen break them (and the other mollusks they eat) open and sell the meat to local restaurants. Tourists who comb the beaches pluck snails off the rocks and toss them aside.
A severe earthquake in 2020 thrust formerly submerged parts of their habitat above sea level, fatally tossing other mollusks in the snail’s food web to the air, and making once inaccessible places more available to poachers.
Decades ago, dense clusters of snails the size of doorknobs were easy to find, according to Mr. Avendaño. “Full of snails,” he said, sweeping a calloused, violet-stained hand across the coves. Now, most of the snails he finds are small, just over an inch, and yield only a few milliliters of dye.
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