Science
Fed up with perimenopause or menopause? The We Do Not Care Club is here for you
Melani Sanders is over it.
She’s over meticulously applying makeup before leaving the house or, even, having to wear a bra when running errands. She’s over wasting time plucking chin hairs, searching for brain fog-induced lost reading glasses and — most of all — withholding her opinions so as not to offend others.
As a 45-year-old perimenopausal woman, Sanders is no longer searching for outside validation and is over people-pleasing.
The dedication page in her new book sums it up best: “To the a— who told me I had a “computer box booty.”
Who is this dude, and is Sanders worried about offending him?
She doesn’t care.
Author, Melani Sanders, in an outfit she typically wears in her social media videos.
(Surej Kalathil Sunman Media)
That’s Sanders’ mantra in life right now. Last year, the West Palm Beach, Fla.-based mother of three founded the We Do Not Care Club, an online “sisterhood” into the millions of perimenopausal, menopausal and post-menopausal women “who are putting the world on notice that we simply do not care much anymore.” Sanders’ social media videos feature her looking disheveled — in a bathrobe and reading glasses, for example, with additional pairs of reading glasses hanging from her lapels — while rattling off members’ comments about what they do not care about anymore.
“We do not care if we still wear skinny jeans — they stretch and they’re comfortable,” she reads, deadpan. “We do not care if the towels don’t match in our house — you got a rag and you got a towel, use it accordingly.”
Sanders’ online community of fed up women grew rapidly. She announced the club in May 2025, and it has more than 3 million members internationally; celebrity supporters include Ashley Judd, Sharon Stone and Halle Berry. It’s a welcoming, if unexpected, space where women “can finally exhale,” as Sanders puts it. The rallying cry? “We do not give a f—ing s— what anyone thinks of us anymore.”
That’s also the message of Sanders’ new book, “The Official We Do Not Care Club Handbook: A Hot-Mess Guide for Women in Perimenopause, Menopause, and Beyond Who Are Over It.” The book is part self-help book, with facts about the perimenopause and menopause transition; part memoir; part practical workbook with tools and resources; and part humor book, brimming with Sanders’ raw and authentic comedic style. (It includes a membership card for new club inductees and cutout-able patches with slogans like “lubricated and horny” or “speaking your truth.”)
We caught up with Sanders while she was in New York to promote her book and admittedly “overstimulated from all the horns,” she said. But she just. Did. Not. Care.
This interview has been edited for length and clarity.
The We Do Not Care Club came about after you had a meltdown in a supermarket parking lot. Tell us about that.
I was in the parking lot of Whole Foods. I needed Ashwagandha — that was my holy grail at the time for my perimenopause journey, and I was out of it. I got back in my car and looked at myself in the rear view mirror. I had on a sports bra that was shifted to one side. My hair was extremely unstructured. I had a hat on and socks mismatched — I was a real hot mess. Nothing added up. But in that moment, I realized that I just didn’t care much anymore. I just said, “Melanie, you have to take the pressure off, girlfriend. It’s time to stop caring so much.” I decided to press the record button and see if anyone wanted to join me in starting a club called the We Do Not Care Club. I released the video and drove home, which took about 20 minutes, and by the time I got home it had [gone viral].
You got hundreds of thousands of new followers, internationally, within 24 hours. Why do you think the post resonated so greatly at that moment?
I had to dissect that because it was kind of unreal. Like, what is it about country, old Melanie that hit record and asked about a little club that she thought maybe 20 or 30 women would want to join? Over the summer, I studied this and did more videos and I listened. It was the relatability. It was the understanding. It was just letting my guard down and just saying it out loud. Speaking my truth. Also, for many women, we have this silent pressure to get it all done. But we’re at capacity. In the book, I talk about how, once I was in perimenopause, I didn’t want to have sex with my husband. I didn’t want to see my kids — like, everyone just close the door! And that’s kind of shameful, you know? It’s not like I don’t love my family. I really do. But I can’t do it all anymore. And I just think that resonated with a lot of sisters throughout the world. It was like: Now is the time for us to just explode and I think we all did it at once.
“The Official We Do Not Care Club Handbook.”
(William Morrow)
You entered perimenopause (or “Miss Peri,” as you call it) at age 44, after a partial hysterectomy. How did your life change after that?
I did not expect it. I knew that I had fibroids and I was uncomfortable because of that. So when I had the hysterectomy, I was expecting to now be a whole person again afterwards. But I just went into this dark place. It was like you’re fighting against yourself to just be normal again. And your body is changing in so many ways. For me, that was the hot flashes, the insomnia, the depression, the rage. My joints were really, really stiff all of a sudden. It’s like, ‘wait a minute, how and why?!!’ And [I got] frozen shoulder. Frozen shoulder was how I discovered I was in perimenopause because I was not told by my doctor who performed my hysterectomy that this could happen. And I didn’t know where to turn or where to go because I was just being told everything was normal. I was so frustrated with the process, the lack of education, the lack of resources. The lack of compassion, I would even say.
Your book and social media videos are so funny. Do you have a comedy background?
I don’t, and I get asked that often. I just say what’s on my mind and sometimes, I guess, it comes out funny — but I’m not trying. The [wearing multiple pairs of] glasses: I do that because, with perimenopause, my eyesight went bad really quickly. I was out in public one day and I could not read. I was just traumatized. So every time I would see glasses, I would just put them on me because I don’t want to get stuck without them. That neck pillow, when I got frozen shoulder, I was using it a lot. Then one day when I hit record, I had the neck pillow on and I just didn’t care. And it stuck.
You’ve appeared on TV, been featured in publications, and People magazine named you creator of the year for 2025. What has this sudden fame been like for you?
It’s surreal. I have not completely processed it yet. It’s a lot to take in. I’m just an everyday woman that decided to press record and accidentally started a movement. Impostor syndrome is there from time to time. But I’m just trying my best to accept everything that’s going on — and keep just being Melani.
Has the overwhelming response from new members fueled your own resolve to be true to yourself or otherwise changed you personally?
It absolutely has. It’s the strength that the sisterhood gives me. Because I’m very scared. You know, the book is coming out. And the tour is sold out in several cities. This is all within an eight-month span. It’s a lot. But when everyone is saying they love you, and when you have a group of women that understands you and feels the way that you feel, absolutely, there’s strength in numbers. Now I don’t care about making mistakes.
You live in a very male household. What do your sons and husband think of all this?
Once I decided that I didn’t care anymore, I just expected for them to kind of allow things just to go to hell around the house — but it was quite the opposite. All three of my sons and my husband, they’re just very supportive. Because it was very sad for me. It was very hard to not want to watch movies or anything and just be by myself. But they rose to the occasion and they make sure things are done when they’re home. They really show how they love their mom during this time.
How can other men become allies to the women they love during the menopause transition?
Just either get out of our way or, you know, just kind of read the room! Because we don’t know who we are from day to day. We don’t know what’s gonna ache. We don’t know what’s going to hurt or what’s going to itch or what’s going to be dry. And if it’s an off day, then darling, it’s just an off day — and it’s OK.
What are some things that you do still care about greatly?
I care about sisterhood. Because when women bind together, it’s a game changer. We will move mountains. I just think that, in this world, there’s so much pressure, so much overstimulation. So I care about being able to live authentically. To feel free. To be OK with who you are. Within WDNC, the two things that I definitely want to convey that I care about is: that you are enough. And you are not alone. And of course I love my kids. I love my family immensely.
Where does the WDNC go from here? What’s the future?
Retreats. That is definitely a dream. To have a weekend retreat where women can come and the only thing that you need to bring is some clean underwear and some pantyliners! (You can’t have a good, hard laugh or a good sneeze or a good cough without pissing your pants.) No makeup, no nothing, just come and be free. I want three different rooms. One will be the rage room and you’ll go in there and just throw stuff around and scream and punch, whatever you want. Then a quiet room. No talking, no nothing, just silence. And the last room will be the “Let that s— go room.” That’s where we’ll put everything that we have in us, that we’re holding onto that’s keeping us from living a blissful and peaceful life, and write it down and let it go. I just want to touch sisters and let them know it is OK. We are OK. I have my s— I go through. You have your s— you go through. It’s OK. Let’s live.
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Science
Torrance residents call for the ban of ‘flesh-eating’ chemical used at refinery
Residents and advocates gathered Saturday to demand the ban of a chemical that’s used at a Torrance oil refinery and that they say has the potential to cause a mass casualty disaster.
Hydrofluoric acid is used in about 40 gasoline refineries across the United States, according to the National Resources Defense Council. The defense council states that “exposing as little as 1% of a person’s skin to HF (about the size of one’s hand) can lead to death. When inhaled, HF can fatally damage lungs, disrupt heart rhythms, and cause other serious health effects.”
The Torrance Refinery uses modified hydrofluoric acid, or MHF, which the refinery considers to be a safer alternative to HF, though the claim is disputed by advocates. Steve Goldsmith, president of the Torrance Refinery Action Alliance, which hosted the Saturday event, said that if MHF were to be been released into the air, it would create irreversible health effects within 6.2 miles of the refinery, trickling into other parts of Los Angeles County.
And in 2015, he said, this almost happened.
On Feb. 18, 2015, there was an explosion at the refinery, then operated by ExxonMobil, caused by the rupture of an eroded valve. The incident, which released flammable hydrocarbons, injured four workers and forced 14 schools into lockdown.
The Saturday event, held at North High School’s Performing Arts Center in Torrance, marked the 11th anniversary of the explosion.
Goldsmith described the chemical as “murderous.”
Audience members participate in a “peace clap” at North Torrance High as they listen to speakers against the use of hydrofluoric acid in the Los Angeles region and across the country.
(Allen J. Schaben / Los Angeles Times)
“Torrance Refinery had an enormous explosion, and a piece of equipment the size of a bus came within five feet of the hydrofluoric acid, causing a near miss,” Goldsmith said. “We’ve been working to get rid of it.”
Residents like Christopher Truman say replacing MHF with an alternative option is the least that can be done. His parents live near the refinery.
“I’m born and raised in the South Bay, and my family lives in, effectively, what would be the blast radius if another accident happened,” Truman said. “So just in that aspect, I’m very worried about it.”
MHF is also used to clean semiconductor surfaces and produce pesticides and herbicides in the agricultural and pharmaceutical industries, according to the Torrance Refinery.
County Supervisor Janice Hahn said residents should not assume “they will be lucky” if another refinery accident were to occur.
“Only two refineries in California use MHF, Torrance Refinery and the Valero Refinery in Wilmington,” Hahn said. “MHF is simply too dangerous to use. It is a flesh-eating, low-crawling, toxic vapor cloud. Our communities will not be safe until this chemical is gone.”
Goldsmith said a Chevron refinery in Salt Lake City found an ionic-liquid alkylation process as an alternative to MHF. He added that the 2025 Chevron refinery explosion in El Segundo “would have been different if they had been using MHF.”
“They used another chemical that did not endanger the community,” Goldsmith said. “And that’s the thing about refineries, they have explosions. But that’s why you can’t have [MHF] around things that can blow up.”
U.S. Representative
U.S. Rep. Maxine Waters (D-Los Angeles) appears on a video message explaining her legislation, which she says will have a positive impact for communities in the Los Angeles region.
(Allen J. Schaben / Los Angeles Times)
U.S. Rep. Maxine Waters, (D-Los Angeles), who represents the city of Torrance, greeted attendees in a prerecorded message, in which she reintroduced her bill, the “Preventing Mass Casualties from Release of Hydrofluoric Acid at Refineries Act,” which targets plants using MHF.
“I originally introduced this bill in December of 2024,” Waters said in the video. “I faced considerable opposition, especially from the United Steel Workers Union, [who were] concerned that if refineries converted to safer technologies, some of the refineries might close, leaving workers without jobs. They agreed with me that hydrofluoric acid is dangerous. But they still would not support my bill. So I decided to go ahead and reintroduce this bill, [without] union support.”
The bill would give refineries five years to find an alternative to the dangerous chemical. Violators may be subject to fines up to $37,000 per infraction.
Los Angeles County Supervisor Janice Hahn speaks out against the use of hydrofluoric acid.
(Allen J. Schaben / Los Angeles Times)
Some residents stressed the need for transparency from local officials.
Ian Patton, a Long Beach resident, said most parts of the investigation into the 2015 explosion were withheld.
“Why can’t they not make this report public? The [Torrance Refinery Action Alliance] has been asking for it for years,” Patton said. “The next step was to look at litigation under the California Public Records Act. It’s not something that we want to do, but the public deserves to know whether these plants are safe.”
Science
TrumpRx is launched: How it works and what Democrats say about it
WASHINGTON — The White House’s TrumpRx website went live Thursday with a promise to instantly deliver prescription drugs at “the lowest price anywhere in the world.”
“This launch represents the largest reduction in prescription drug prices in history by many, many times, and it’s not even close,” President Trump said at a news conference announcing the launch of the platform.
Drug policy experts say the jury is still out on whether the platform will provide the significant savings Trump promises, though it will probably help people who need drugs not commonly covered by insurance.
Senate Democrats, meanwhile, called the site a “vanity project” and questioned whether the program presents a possible conflict of interest involving the pharmaceutical industry and the Trump family.
What is TrumpRx, really?
The new platform, trumprx.gov, is designed to help uninsured Americans find discounted prices for high-cost, brand-name prescriptions, including fertility, obesity and diabetes treatments.
The site does not directly sell drugs. Instead, consumers browse a list of discounted medicines, and select one for purchase. From there, they either receive a coupon accepted at certain pharmacies or are routed directly to a drug manufacturer’s website to purchase the prescription.
The White House said the reduced prices are possible after the administration negotiated voluntary “most favored nation” agreements with 16 major drugmakers including Pfizer, Eli Lilly and Novo Nordisk.
Under these deals, manufacturers have agreed to set certain U.S. drug prices no higher than those paid in other wealthy nations in exchange for three-year tariff exemptions. However, the full legal and financial details of the deals have not been made public, leaving lawmakers to speculate how TrumpRx’s pricing model works.
What does it accomplish?
Though the White House has framed TrumpRx as a historic reset for prescription drug costs, economists said the platform offers limited new savings.
But it does move the needle on the issue of drug pricing transparency, away from the hidden mechanisms behind how prescription drugs are priced, rebated and distributed, according to Geoffrey Joyce, director of health policy at the USC Schaeffer Center for Health Policy and Economics.
“This has been a murky world, a terrible, obscure, opaque marketplace where drug prices have been inconsistently priced to different consumers,” Joyce said, “So this is a little step in the right direction, but it’s mostly performative from my perspective, which is kind of Trump in a nutshell.”
Still, for the uninsured or people seeking “lifestyle drugs” — like those for fertility or weight loss that insurers have historically declined to cover — TrumpRx could become a useful option, Joyce said.
“It’s kind of a win for Trump and a win for Pfizer,” Joyce said. “They get to say, ‘Look what we’re doing. We’re lowering prices. We’re keeping Trump happy, but it’s on our low-volume drugs, and drugs that we were discounting big time anyway.’”
Where does it fall short?
Early analyses by drug policy experts suggest many of the discounted medications listed on the TrumpRx site were already on offer through other drug databases before the platform launched.
For example, Pfizer’s Duavee menopause treatment is listed at $30.30 on TrumpRx, but it is also available for the same price at some pharmacies via GoodRx.
Weight management drug Wegovy starts at $199 on TrumpRx. Manufacturers were already selling the same discounted rates through its NovoCare Pharmacy program before the portal’s launch.
“[TrumpRx] uses data from GoodRx, an existing price-search database for prescription drugs,” said Darius N. Lakdawalla, a senior health policy researcher at USC. “It seems to provide prices that are essentially the same as the lowest price GoodRx reports on its website.”
Compared to GoodRx, TrumpRx covers a modest subset of drugs: 43 in all.
“Uninsured consumers, who do not use or know about GoodRx and need one of the specific drugs covered by the site, might benefit from TrumpRx. That seems like a very specific set of people,” Lakdawalla said.
Where do Democrats stand?
Democrats slammed the program this week, saying it would not provide substantial discounts for patients, and called for greater transparency around the administration’s dealings with drugmakers. To date, the administration has not disclosed the terms of the pricing agreements with manufacturers such as Pfizer and AstraZeneca.
In the lead-up to the TrumpRx launch, Democratic members of Congress questioned its usefulness and urged federal health regulators to delay its debut.
“This is just another Donald Trump pet project to rebrand something that already exists, take credit for it, and do nothing to actually lower healthcare prices,” Sen. Alex Padilla (D-Calif.) said Friday. “Democrats will continue fighting to lower healthcare costs and push Republicans to stop giving handouts to billionaires at the expense of working-class Americans.”
Three other Democratic senators — Dick Durbin, Elizabeth Warren and Peter Welch — raised another concern in a Jan. 29 letter to Thomas March Bell, inspector general for the Department of Health and Human Services.
The three senators pointed to potential conflicts of interest between TrumpRx and an online dispensing company, BlinkRx.
One of Trump’s sons, Donald Trump Jr., joined the BlinkRx Board of Directors in February 2025.
Months before, he became a partner at 1789 Capital, a venture capital firm that holds a significant stake in BlinkRx and led the startup’s $140-million funding round in 2024. After his appointment, BlinkRx launched a service to help pharmaceutical companies build direct-to-patient sales platforms quickly.
“The timing of the BlinkRx announcement so closely following the administration’s outreach to the largest drug companies, and the involvement of President Trump’s immediate family, raises questions about potential coordination, influence and self-dealing,” according to an October 2025 statement by Democrats on the House Energy and Commerce Committee.
Both BlinkRx and Donald Trump Jr. have denied any coordination.
What’s next?
The rollout of TrumpRx fits into a suite of White House programs designed to address rising costs, an area of vulnerability for Republicans ahead of the November midterms.
The White House issued a statement Friday urging support for the president’s healthcare initiative, dubbed “the great healthcare plan,” which it said will further reduce drug prices and lower insurance premiums.
For the roughly 8% of Americans without health insurance, TrumpRx’s website promises that more high-cost, brand-name drugs will be discounted on the platform in the future.
“It’s possible the benefits will become broader in the future,” Lakdawalla said. “I would say that the jury remains out on its long-run structure and its long-run pricing effects.”
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