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Extreme heat may have increased spread of H5N1 at poultry farm

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Extreme heat may have increased spread of H5N1 at poultry farm

An H5N1 outbreak that recently infected five poultry workers and 1.8 million chickens in northeast Colorado may have been fueled in part by heat wave conditions and slaughtering methods, according to federal health authorities.

At a press conference Tuesday, Nirav Shah, principal deputy director of the U.S. Centers for Disease Control and Prevention, said the human infections occurred as poultry workers culled infected birds in 104-degree heat — a condition that may have made wearing protective clothing and equipment nearly intolerable, and necessitated the use of large fans, which may have promoted the virus’s spread via feathers, dust and other poultry detritus.

In addition, the method used to kill the infected chickens — carbon dioxide gassing — required that workers move “from chicken to chicken” increasing their “degree of interaction with each potentially infected bird.”

“This confluence of factors may play a role in explaining why this outbreak occurred where it did and when it did,” said Shah, noting that a state and federal investigation is still underway.

He said these observations potentially “highlight a pathway for prevention,” which would include more systematic use of protective equipment as well as engineering adaptations that could help reduce exposure risk.

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This weekend, Colorado and federal health officials reported five cases of bird flu in poultry workers at a single farm in northeast Colorado. Four of the cases have been confirmed by the CDC, and a fifth is considered presumptive as officials wait for the final results.

The poultry farm was infected by bird flu earlier this month. The virus is particularly deadly to poultry, and highly transmissible. Standard practice in the industry is to cull all potentially infected birds and clean the premises.

Federal officials said the chickens were slaughtered with carbon dioxide, which a 2016 Meat and Poultry magazine article described as the “gas of choice” in North America due to its availability, low cost, and track record for “attaining consistency in terms of good animal welfare and meat quality.”

Birds infected with H5N1 are discarded and do not enter the food supply.

The technique requires that workers place chickens in a sealed, portable unit in which anywhere from 20 to “several dozen” are exposed to the gas. At first the CO2 is emitted at a concentration that will render the birds unconscious — a phase of slaughter known as “the induction of insensibility.” Once the birds are knocked out, the concentration is increased, and the animals suffocate and die.

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The whole thing takes “less than a minute and a half,” said Julie Gauthier, executive director for field operations at the USDA’s Animal and Plant Health Inspection Service.

Maurice Pitesky, an expert in poultry health and food safety epidemiology at UC Davis, said for “houses” as big as the one in Colorado, culling can take weeks.

The process requires that workers handle both live and dead birds. And officials on Tuesday’s call hypothesized that if their PPE was not on properly due to the excessive heat, or had been made less effective by large cooling fans (which were also kicking up dust), they may have been exposed and vulnerable to the virus.

“The heat is an issue,” Pitesky said. “The expectation that dairy workers, poultry workers, under those current heat conditions — or California’s Central Valley, for example, when it was over 110 degrees — that they would wear PPE like Tyvek suits that don’t breathe at all, and the N95 masks that USDA is offering for free, is unrealistic.”

He said there was “no way” anyone was going to wear PPE in those conditions. Instead, he said, the USDA should provide things like visors or surgical masks — protective items that might actually be worn.

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“Then there’s the culture, which is probably the bigger issue,” he said, noting in his experience, most workers won’t wear masks — even for particulate matter. So, “while the USDA intentions were good, I think the practicality of what they were trying to bring about wasn’t very sensitive to that reality.”

Federal officials also noted that DNA sequencing of virus obtained from one of the patients is closely related both to infected chickens from that farm, as well as to the first dairy worker infected in Texas in April and to infected dairy herds located near the Colorado poultry farm.

The finding raises “the possibility that this virus was transmitted from a dairy herd in Colorado to the poultry farm,” said Shah, from the CDC. “That is a hypothesis … that needs and requires a full investigation.”

Pitesky said the finding implies the virus may be moving between workers employed at multiple farms, or equipment that’s being shared, “or there’s potentially some environmental connection through groundwater or some kind of habitat-type transmission.”

He said birds and rodents can be mechanical transmitters, and wild birds are common visitors in both dairy and poultry farms. He said he works with poultry farmers to keep birds from nesting inside — “that’s a no-no” — but birds, such as swallows, can and do fly through.

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He also suggested that while poultry farmers have really upped their biosecurity in the past several years, the dairy industry is “light-years” behind when it comes to creating physical barriers.

He said with every update he hears, it’s becoming increasingly clear “there’s no way to model or predict how this virus is going to move when it’s in this many different species and in this many different environments.”

And it’s anyone’s guess, he said, what’s going to happen this fall when fall migration begins and things potentially get even more complex.

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What’s in a Name? For These Snails, Legal Protection

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What’s in a Name? For These Snails, Legal Protection

The sun had barely risen over the Pacific Ocean when a small motorboat carrying a team of Indigenous artisans and Mexican biologists dropped anchor in a rocky cove near Bahías de Huatulco.

Mauro Habacuc Avendaño Luis, one of the craftsmen, was the first to wade to shore. With an agility belying his age, he struck out over the boulders exposed by low tide. Crouching on a slippery ledge pounded by surf, he reached inside a crevice between two rocks. There, lodged among the urchins, was a snail with a knobby gray shell the size of a walnut. The sight might not dazzle tourists who travel here to see humpback whales, but for Mr. Avendaño, 85, these drab little mollusks represent a way of life.

Marine snails in the genus Plicopurpura are sacred to the Mixtec people of Pinotepa de Don Luis, a small town in southwestern Oaxaca. Men like Mr. Avendaño have been sustainably “milking” them for radiant purple dye for at least 1,500 years. The color suffuses Mixtec textiles and spiritual beliefs. Called tixinda, it symbolizes fertility and death, as well as mythic ties between lunar cycles, women and the sea.

The future of these traditions — and the fate of the snails — are uncertain. The mollusks are subject to intense poaching pressure despite federal protections intended to protect them. Fishermen break them (and the other mollusks they eat) open and sell the meat to local restaurants. Tourists who comb the beaches pluck snails off the rocks and toss them aside.

A severe earthquake in 2020 thrust formerly submerged parts of their habitat above sea level, fatally tossing other mollusks in the snail’s food web to the air, and making once inaccessible places more available to poachers.

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Decades ago, dense clusters of snails the size of doorknobs were easy to find, according to Mr. Avendaño. “Full of snails,” he said, sweeping a calloused, violet-stained hand across the coves. Now, most of the snails he finds are small, just over an inch, and yield only a few milliliters of dye.

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Video: This Parrot Has No Beak, But Is at the Top of the Pecking Order

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Video: This Parrot Has No Beak, But Is at the Top of the Pecking Order

new video loaded: This Parrot Has No Beak, But Is at the Top of the Pecking Order

Bruce, a disabled kea parrot, is missing his top beak. The bird uses tools to keep himself healthy and developed a jousting technique that has made him the alpha male of his group.

By Meg Felling and Carl Zimmer

April 20, 2026

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Contributor: Focus on the real causes of the shortage in hormone treatments

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Contributor: Focus on the real causes of the shortage in hormone treatments

For months now, menopausal women across the U.S. have been unable to fill prescriptions for the estradiol patch, a long-established and safe hormone treatment. The news media has whipped up a frenzy over this scarcity, warning of a long-lasting nationwide shortage. The problem is real — but the explanations in the media coverage miss the mark. Real solutions depend on an accurate understanding of the causes.

Reporters, pharmaceutical companies and even some doctors have blamed women for causing the shortage, saying they were inspired by a “menopause moment” that has driven unprecedented demand. Such framing does a dangerous disservice to essential health advocacy.

In this narrative, there has been unprecedented demand, and it is explained in part by the Food and Drug Administration’s recent removal of the “black-box warning” from estradiol patches’ packaging. That inaccurate (and, quite frankly, terrifying) label had been required since a 2002 announcement overstated the link between certain menopause hormone treatments and breast cancer. Right-sizing and rewording the warning was long overdue. But the trouble with this narrative is that even after the black-box warning was removed, there has not been unprecedented demand.

Around 40% of menopausal women were prescribed hormone treatments in some form before the 2002 announcement. Use plummeted in its aftermath, dipping to less than 5% in 2020 and just 1.8% in 2024. According to the most recent data, the number has now settled back at the 5% mark. Unprecedented? Hardly. Modest at best.

Nor is estradiol a new or complex drug; the patch formulation has existed for decades, and generic versions are widely manufactured. There is no exotic ingredient, no rare supply chain dependency, no fluke that explains why women are suddenly being told their pharmacy is out of stock month after month.

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The story is far more an indictment of the broken insurance industry: market concentration, perverse incentives and the consequences of allowing insurance companies to own the pharmacy benefit managers that effectively control drug access for the majority of users. Three companies — CVS Caremark, Express Scripts and OptumRx — manage 79% of all prescription drug claims in the United States. Those companies are wholly owned subsidiaries of three insurance behemoths: CVS Health, Cigna and UnitedHealth Group, respectively. This means that the same corporation that sells you your insurance plan also decides which drugs get covered, at what price, and whether your pharmacy can stock them. This is called vertical integration. In another era, we might have called it a cartel. The resulting problems are not unique to hormone treatments; they have affected widely used medications including blood thinners, inhalers and antibiotics. When a low-cost generic such as estradiol — a medication with no blockbuster profit margins and no patent protection — runs into friction in this system, the friction is not random. It is structural. Every decision in that chain is filtered through the same corporate profit motive. And when the drug in question is an off-patent estradiol patch that has negligible profit margins because of generic competition but requires logistical investment to keep consistently in stock? The math on “how much does this company care about ensuring access” is not complicated.

Unfortunately, there is little financial incentive to ensure smooth, consistent access. There is, however, significant financial incentive to steer patients toward branded alternatives, or simply to let supply tighten — because the companies aren’t losing much profit if sales of that product dwindle. This is not a conspiracy theory: The Federal Trade Commission noted this dynamic in a report that documented how pharmacy benefit managers’ practices inflate costs, reduce competition and harm patient access, particularly for independent pharmacies and for generic drugs.

Any claim that the estradiol patch shortage is meaningfully caused by more women now demanding hormone treatments is a distraction. It is also misogyny, pure and simple, to imply that the solution to the shortage is for women’s health advocates to dial it down and for women to temper their expectations. The scarcity of estradiol patches is the outcome of a broken system refusing to provide adequate supply.

Meanwhile, there are a few strategies to cope.

  • Ask your prescriber about alternatives. Estradiol is available in multiple formulations, including gel, spray, cream, oral tablet, vaginal ring and weekly transdermal patch, which is a different product from the twice-weekly patch and may be more consistently available depending on manufacturer and region.
  • Consider an online pharmacy. Many are doing a good job locating and filling these prescriptions from outside the pharmacy benefit manager system.
  • Call ahead. Patch shortages are inconsistent across regions and distributors. A call to pharmacies in your area, or a broader geographic radius if you’re able, can locate stock that your regular pharmacy doesn’t have.
  • Consider a compounding pharmacy. These sources can sometimes meet needs when commercially manufactured products are inaccessible. The hormones used are the same FDA-regulated bulk ingredients.

Beyond those Band-Aid solutions, more Americans need to fight for systemic change. The FTC report exists because Congress asked for it and committed to legislation that will address at least some of the problems. The FDA took action to change the labeling on estrogen in the face of citizen and medical experts’ pressure; it should do more now to demand transparency from patch manufacturers.

Most importantly, it is on all of us to call out the cracks in the current system. Instead of repeating “there’s a patch shortage” or a “surge in demand,” say that a shockingly small minority of menopausal women still even get hormonal treatments prescribed at all, and three drug companies control the vast majority of claims in this country. Those are the real problems that need real solutions.

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Jennifer Weiss-Wolf, the executive director of the Birnbaum Women’s Leadership Center at New York University School of Law, is the author of the forthcoming book When in Menopause: A User’s Manual & Citizen’s Guide. Suzanne Gilberg, an obstetrician and gynecologist in Los Angeles, is the author of “Menopause Bootcamp.”

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