Connect with us

Health

Wuhan Market Samples Contained Covid and Animal Mixtures, Report Says

Published

on

Wuhan Market Samples Contained Covid and Animal Mixtures, Report Says

On Jan. 12, 2020, Chinese language investigators combing a marketplace for clues concerning the outbreak of a mysterious new sickness within the metropolis of Wuhan swabbed a cart. It was the type usually used for transporting animal cages, and it got here again optimistic for the coronavirus.

Three years later, a crew of worldwide specialists has sifted via the genetic contents of that swab, which had been quietly uploaded to a global database and made public solely this 12 months. In a report launched on Monday evening, the scientists described intimately for the primary time proof from the swab that they are saying strengthens the case that illegally traded wild animals ignited the coronavirus pandemic.

Chinese language researchers who had initially uploaded the uncooked information had it faraway from the database after they had been contacted by the worldwide crew. Now directors of the database itself have minimize off entry to the worldwide scientists for what they mentioned had been guidelines violations, elevating questions concerning the database’s personal position within the tug of struggle over entry to information that might make clear the origins of a virus that has killed seven million folks.

Together with genetic signatures of the coronavirus, the swab from the cart contained greater than 4,500 prolonged fragments of genetic materials from raccoon canine, the report mentioned. It had none from people. Some Covid-positive swabs taken from different objects and surfaces on the market, the report mentioned, additionally had extra genetic materials from animals than from people.

Discovering genetic footprints from animals in the identical place as genetic materials from the virus doesn’t show that the animals themselves had been contaminated. However some scientists who reviewed the report mentioned that the dominance of genetic materials from animals — and particularly raccoon canine — steered that species recognized to have the ability to unfold the coronavirus had been certainly carrying infections on the market in late 2019.

Advertisement

That state of affairs, they mentioned, was in line with the virus spilling into people from market animals and touching off the pandemic, a set of circumstances just like the one which gave rise to the primary SARS outbreak in China 20 years earlier.

“You have a look at them and say these are most likely contaminated animals,” Theodora Hatziioannou, a virologist at The Rockefeller College in New York who was not concerned within the analysis, mentioned of the newest findings. “If it was a human shedding the virus, one would anticipate finding human DNA there, too.”

The swabs may but maintain extra clues about the place the virus within the samples had come from. The report mentioned, as an illustration, that there was proof of specific genes that might counsel the fabric had come from a raccoon canine’s higher respiratory tract.

Even when an animal had been contaminated, nonetheless, it could not be clear that it had unfold the virus to folks. Somebody contaminated with the virus may have gotten a market animal sick. And solely by swabbing animals instantly may scientists show whether or not they had been carrying the virus, a step that was precluded by the market being cleared of animals quickly after the outbreak started.

The report has been the topic of intense hypothesis because the worldwide specialists offered their findings to the World Well being Group final week after which raced to compile their analyses. On the identical time, the findings set off a battle for entry to the genetic sequences at their coronary heart.

Chinese language scientists had initially uploaded the uncooked sequences to a world database a while after publishing a research describing them final 12 months. However as soon as the worldwide specialists found the info in early March and alerted Chinese language researchers to what they’d discovered, the info was taken offline.

Advertisement

Final week, the W.H.O. rebuked China for hiding such essential data from the remainder of the world for 3 years. Now the nonprofit group based mostly in Munich that runs the database, known as GISAID, has come below scrutiny for its position in controlling entry to the info.

Within the new report, the worldwide crew of scientists mentioned that GISAID had “deviated from its acknowledged mission” in permitting the Chinese language researchers to withhold the info for thus lengthy.

The database directors responded to the report on Tuesday by slicing off the crew members’ entry to their on-line accounts and saying that they’d violated its guidelines by getting out forward of the Chinese language scientists and posting their very own evaluation. The scientists mentioned that they hewed to GISAID’s database-access settlement in downloading and learning the sequences, and famous that they’d made a number of presents to work with the Chinese language scientists.

“The ramifications of slicing off entry to this group of authors are big,” mentioned Michael Worobey, an evolutionary biologist on the College of Arizona and co-author of the brand new report, noting that GISAID additionally jeopardized work by crew members associated to coronavirus variants and flu preparedness. “They’re making false accusations.”

The worldwide crew homed in on raccoon canine — fluffy mammals associated to foxes and offered for meat and fur — due to how a lot of the animals’ genetic materials was present in the important thing swab from the cart and since they’re recognized to unfold the virus. They mentioned their findings had been in line with that animal harboring the virus, which originated in bats, and passing it to people on the market.

Advertisement

“This isn’t an contaminated animal,” mentioned Joel Wertheim, an evolutionary biologist on the College of California, San Diego and a co-author of the report, referring to the brand new genetic information. “However that is the closest you will get with out having the animal in entrance of you.”

The report, although, additionally provided essentially the most concrete proof thus far of different animals inclined to the virus being offered on the market, famous Kristian Andersen, a virologist on the Scripps Analysis Institute in La Jolla, Calif., and a co-author of the report. Genetic materials from these animals — just like the masked palm civet, a small Asian mammal that was implicated within the SARS outbreak 20 years in the past — was additionally present in swabs that had been optimistic for the coronavirus.

“It’s actually Disney Land for zoonotic switch,” mentioned Joseph DeRisi, a professor of biochemistry on the College of California, San Francisco, and president of the Chan Zuckerberg Biohub, referring to the vary of animals documented within the report.

Quite a few different swabs on the market discovered giant portions of human genetic materials — a sign, the report mentioned, of sure virus samples probably being shed by contaminated folks. Lots of the earliest recognized Covid sufferers labored or shopped on the market.

Nonetheless different optimistic swabs, the report mentioned, had been dominated by genetic materials from animals that aren’t believed to be inclined to the virus. A pattern taken from a fish packaging floor, for instance, contained loads of fish genetic materials. That virus was prone to have been deposited by an individual, scientists mentioned, illustrating that substantial quantities of animal genetic materials didn’t essentially imply that animals had produced the virus there.

Advertisement

Citing these findings, some scientists mentioned that the sorts of swabs analyzed within the report merely couldn’t provide conclusive proof of an contaminated animal.

“The report does include helpful data,” Sergei Pond, a virologist at Temple College in Philadelphia, mentioned. However, he added, “Does it inform you something about which animal was contaminated? It actually doesn’t.”

Dr. David Relman, a microbiologist at Stanford, mentioned that it was tough to evaluate the findings with out extra particulars about how the Chinese language investigators had collected and analyzed their swabs. The Chinese language paper final 12 months, he famous, described utilizing a equipment to filter out human genetic materials and make the assessments extra delicate to the virus.

However quite a lot of swabs from the Chinese language researchers described within the worldwide crew’s report contained substantial quantities of human genetic materials, suggesting that these filtering strategies had not depleted the samples of human materials. Dr. DeRisi, who makes a speciality of the kind of evaluation described within the report, mentioned that such kits had been usually ineffective at eradicating the genetic signatures of individuals.

Frederic Bushman, a microbiologist on the College of Pennsylvania who additionally makes a speciality of sequencing strategies, agreed that the report’s strategies had been sound.

Advertisement

“I believe the only clarification is that it’s an contaminated raccoon canine,” he mentioned. “I don’t assume it’s absolute proof.”

Continue Reading
Advertisement
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Health

How Yvette Nicole Brown Lost Weight and Got Her Diabetes Under Control

Published

on

How Yvette Nicole Brown Lost Weight and Got Her Diabetes Under Control


Advertisement


Yvette Nicole Brown’s Weight Loss and Diabetes Management | Woman’s World




















Advertisement














Advertisement


Use left and right arrow keys to navigate between menu items.

Advertisement


Use escape to exit the menu.

Continue Reading

Health

As bird flu spreads, CDC recommends faster 'subtyping' to catch more cases

Published

on

As bird flu spreads, CDC recommends faster 'subtyping' to catch more cases

As cases of H5N1, also known as avian flu or bird flu, continue to surface across the U.S., safety precautions are ramping up.

The U.S. Centers for Disease Control and Prevention (CDC) announced on Thursday its recommendation to test hospitalized influenza A patients more quickly and thoroughly to distinguish between seasonal flu and bird flu.

The accelerated “subtyping” of flu A in hospitalized patients is in response to “sporadic human infections” of avian flu, the CDC wrote in a press release.

ONE STATE LEADS COUNTRY IN HUMAN BIRD FLU WITH NEARLY 40 CONFIRMED CASES

“CDC is recommending a shortened timeline for subtyping all influenza A specimens among hospitalized patients and increasing efforts at clinical laboratories to identify non-seasonal influenza,” the agency wrote.

Advertisement

The CDC now recommends accelerated subtyping of influenza A in response to “sporadic human infections” in the U.S. (iStock)

“Clinicians and laboratorians are reminded to test for influenza in patients with suspected influenza and, going forward, to now expedite the subtyping of influenza A-positive specimens from hospitalized patients, particularly those in an intensive care unit (ICU).”

LOUISIANA REPORTS FIRST BIRD FLU-RELATED HUMAN DEATH IN US

The goal is to prevent delays in identifying bird flu infections and promote better patient care, “timely infection control” and case investigation, the agency stated.

These delays are more likely to occur during the flu season due to high patient volumes, according to the CDC.

Advertisement

For more Health articles, visit www.foxnews.com/health

Health care systems are expected to use tests that identify seasonal influenza A as a subtype – so if a test comes back positive for influenza A but negative for seasonal influenza, that is an indicator that the detected virus might be novel.

Patient on hospital bed

Identifying bird flu infections will support better patient care and infection control, the CDC says. (iStock)

“Subtyping is especially important in people who have a history of relevant exposure to wild or domestic animals [that are] infected or possibly infected with avian influenza A (H5N1) viruses,” the CDC wrote.

In an HHS media briefing on Thursday, the CDC confirmed that the public risk for avian flu is still low, but is being closely monitored.

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

Advertisement

The agency spokesperson clarified that this accelerated testing is not due to bird flu cases being missed, as the CDC noted in its press release that those hospitalized with influenza A “probably have seasonal influenza.”

Niels Riedemann, MD, PhD, CEO and founder of InflaRx, a German biotechnology company, said that understanding these subtypes is an “important step” in better preparing for “any potential outbreak of concerning variants.”

Blood collection tubes H5N1 in front of chicken

The CDC recommends avoiding direct contact with wild birds or other animals that may be infected. (iStock)

“It will also be important to foster research and development of therapeutics, including those addressing the patient’s inflammatory immune response to these types of viruses – as this has been shown to cause organ injury and death during the COVID pandemic,” he told Fox News Digital. 

Since 2022, there have been 67 total human cases of bird flu, according to the CDC, with 66 of those occurring in 2024.

Advertisement

The CDC recommends that people avoid direct contact with wild birds or other animals that are suspected to be infected. Those who work closely with animals should also wear the proper personal protective equipment (PPE).

Continue Reading

Health

Sick Prisoners in New York Were Granted Parole but Remain Behind Bars

Published

on

Sick Prisoners in New York Were Granted Parole but Remain Behind Bars

When the letter arrived at Westil Gonzalez’s prison cell saying that he had been granted parole, he couldn’t read it. Over the 33 years he had been locked up for murder, multiple sclerosis had taken much of his vision and left him reliant on a wheelchair.

He had a clear sense of what he would do once freed. “I want to give my testimony to a couple of young people who are out there, picking up guns,” Mr. Gonzalez, 57, said in a recent interview. “I want to save one person from what I’ve been through.”

But six months have passed, and Mr. Gonzalez is still incarcerated outside Buffalo, because the Department of Corrections has not found a nursing home that will accept him. Another New York inmate has been in the same limbo for 20 months. Others were released only after suing the state.

America’s elderly prison population is rising, partly because of more people serving long sentences for violent crimes. Nearly 16 percent of prisoners were over 55 in 2022, up from 5 percent in 2007. The share of prisoners over 65 quadrupled over the same time period, to about 4 percent.

Complex and costly medical conditions require more nursing care, both in prison and after an inmate’s release. Across the country, prison systems attempting to discharge inmates convicted of serious crimes often find themselves with few options. Nursing home beds can be hard to find even for those without criminal records.

Advertisement

Spending on inmates’ medical care is increasing — in New York, it has grown to just over $7,500 in 2021 from about $6,000 per person in 2012. Even so, those who work with the incarcerated say the money is often not enough to keep up with the growing share of older inmates who have chronic health problems.

“We see a lot of unfortunate gaps in care,” said Dr. William Weber, an emergency physician in Chicago and medical director of the Medical Justice Alliance, a nonprofit that trains doctors to work as expert witnesses in cases involving prison inmates. With inmates often struggling to get specialty care or even copies of their own medical records, “things fall through the cracks,” he said.

Dr. Weber said he was recently involved in two cases of seriously ill prisoners, one in Pennsylvania and the other in Illinois, who could not be released without a nursing home placement. The Pennsylvania inmate died in prison and the Illinois man remains incarcerated, he said.

Almost all states have programs that allow early release for inmates with serious or life-threatening medical conditions. New York’s program is one of the more expansive: While other states often limit the policy to those with less than six months to live, New York’s is open to anyone with a terminal or debilitating illness. Nearly 90 people were granted medical parole in New York between 2020 and 2023.

But the state’s nursing home occupancy rate hovers around 90 percent, one of the highest in the nation, making it especially hard to find spots for prisoners.

Advertisement

The prison system is “competing with hospital patients, rehabilitation patients and the general public that require skilled nursing for the limited number of beds available,” said Thomas Mailey, a spokesman for the New York Department of Corrections and Community Supervision. He declined to comment on Mr. Gonzalez’s case or on any other inmate’s medical conditions.

Parolees remain in the state’s custody until their original imprisonment term has expired. Courts have previously upheld the state’s right to place conditions on prisoner releases to safeguard the public, such as barring paroled sex offenders from living near schools.

But lawyers and medical ethicists contend that paroled patients should be allowed to choose how to get their care. And some noted that these prisoners’ medical needs are not necessarily met in prison. Mr. Gonzalez, for example, said he had not received glasses, despite repeated requests. His disease has made one of his hands curl inward, leaving his unclipped nails to dig into his palm.

“Although I’m sympathetic to the difficulty of finding placements, the default solution cannot be continued incarceration,” said Steven Zeidman, director of the criminal defense clinic at CUNY School of Law. In 2019, one of his clients died in prison weeks after being granted medical parole.

New York does not publish data on how many inmates are waiting for nursing home placements. One 2018 study found that, between 2013 and 2015, six of the 36 inmates granted medical parole died before a placement could be found. The medical parole process moves slowly, the study showed, sometimes taking years for a prisoner to even get an interview about their possible release.

Advertisement

Finding a nursing home can prove difficult even for a patient with no criminal record. Facilities have struggled to recruit staff, especially since the coronavirus pandemic. Nursing homes may also worry about the safety risk of someone with a prior conviction, or about the financial risk of losing residents who do not want to live in a facility that accepts former inmates.

“Nursing homes have concerns and, whether they are rational or not, it’s pretty easy not to pick up or return that phone call,” said Ruth Finkelstein, a professor at Hunter College who specializes in policies for older adults and reviewed legal filings at The Times’s request.

Some people involved in such cases said that New York prisons often perform little more than a cursory search for nursing care.

Jose Saldana, the director of a nonprofit called the Release Aging People in Prison Campaign, said that when he was incarcerated at Sullivan Correctional Facility from 2010 through 2016, he worked in a department that helped coordinate parolees’ releases. He said he often reminded his supervisor to call nursing homes that hadn’t picked up the first time.

“They would say they had too many other responsibilities to stay on the phone calling,” Mr. Saldana said.

Advertisement

Mr. Mailey, the spokesman for the New York corrections department, said that the agency had multiple discharge teams seeking placement options.

In 2023, Arthur Green, a 73-year-old patient on kidney dialysis, sued the state for release four months after being granted medical parole. In his lawsuit, Mr. Green’s attorneys said that they had secured a nursing home placement for him, but that it lapsed because the Department of Corrections submitted an incomplete application to a nearby dialysis center.

The state found a placement for Mr. Green a year after his parole date, according to Martha Rayner, an attorney who specializes in prisoner release cases.

John Teixeira was granted medical parole in 2020, at age 56, but remained incarcerated for two and a half years, as the state searched for a nursing home. He had a history of heart attacks and took daily medications, including one delivered through an intravenous port. But an assessment from an independent cardiologist concluded that Mr. Teixeira did not need nursing care.

Lawyers with the Legal Aid Society in New York sued the state for his release, noting that during his wait, his port repeatedly became infected and his diagnosis progressed from “advanced” to “end-stage” heart failure.

Advertisement

The Department of Corrections responded that 16 nursing homes had declined to accept Mr. Teixeira because they could not manage his medical needs. The case resolved three months after the suit was filed, when “the judge put significant pressure” on the state to find an appropriate placement, according to Stefen Short, one of Mr. Teixeira’s lawyers.

Some sick prisoners awaiting release have found it difficult to get medical care on the inside.

Steve Coleman, 67, has trouble walking and spends most of the day sitting down. After 43 years locked up for murder, he was granted parole in April 2023 and has remained incarcerated, as the state looks for a nursing home that could coordinate with a kidney dialysis center three times each week.

But Mr. Coleman has not had dialysis treatment since March, when the state ended a contract with its provider. The prison has offered to take Mr. Coleman to a nearby clinic for treatment, but he has declined because he finds the transportation protocol — which involves a strip search and shackles — painful and invasive.

“They say you’ve got to go through a strip search,” he said in a recent interview. “If I’m being paroled, I can’t walk and I’m going to a hospital, who could I be hurting?”

Advertisement

Volunteers at the nonprofit Parole Prep Project, which assisted Mr. Coleman with his parole application, obtained a letter from Mount Sinai Hospital in New York City in June offering to give him medical care and help him transition back into the community.

Still incarcerated two months later, Mr. Coleman sued for his release.

In court filings, the state argued that it would be “unsafe and irresponsible” to release Mr. Coleman without plans to meet his medical needs. The state also said that it had contacted Mount Sinai, as well as hundreds of nursing homes, about Mr. Coleman’s placement and had never heard back.

In October, a court ruled in the prison system’s favor. Describing Mr. Coleman’s situation as “very sad and frustrating,” Justice Debra Givens of New York State Supreme Court concluded that the state had a rational reason to hold Mr. Coleman past his parole date. Ms. Rayner, Mr. Coleman’s lawyer, and the New York Civil Liberties Union appealed the ruling on Wednesday.

Fourteen medical ethicists have sent a letter to the prison supporting Mr. Coleman’s release. “Forcing continued incarceration under the guise of ‘best interests,’ even if doing so is well-intentioned, disregards his autonomy,” they wrote.

Advertisement

Several other states have come up with a different solution for people on medical parole: soliciting the business of nursing homes that specialize in housing patients rejected elsewhere.

A private company called iCare in 2013 opened the first such facility in Connecticut, which now houses 95 residents. The company runs similar nursing homes in Vermont and Massachusetts.

David Skoczulek, iCare’s vice president of business development, said that these facilities tend to save states money because the federal government covers some of the costs through Medicaid.

“It’s more humane, less restrictive and cost-effective,” he said. “There is no reason for these people to remain in a corrections environment.”

Advertisement
Continue Reading

Trending