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Chemicals in water and household objects could reduce chances of pregnancy, live births: new study

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Chemicals in water and household objects could reduce chances of pregnancy, live births: new study

For girls who’re struggling to conceive, chemical compounds might be the wrongdoer — that is based on a brand new research revealed in Science of the Complete Setting.

The research discovered that ladies whose blood plasma contained larger quantities of PFAS (perfluoroalkyl substances) — chemical compounds typically present in consuming water and in atypical family merchandise — had as much as a 40% decrease probability of being pregnant and reside births.

Researchers from Mount Sinai, an built-in well being system that features the Icahn College of Medication and eight hospital campuses within the New York metropolitan space, targeted on 1,032 Singaporean girls between the ages of 18 and 45 who participated in a population-based research.

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Inside one 12 months of follow-up, the ladies with a mixture of seven PFAS of their blood had been 30% to 40% much less more likely to conceive and ship a reside delivery.

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Dr. Marc Siegel, scientific professor of medication at NYU Langone Medical Middle and a Fox Information medical contributor, was not shocked by the findings (he was not concerned within the research) — provided that PFAS are linked to plastics, that are on the rise. 

Dr. Marc Siegel of New York Metropolis famous that PFAS are linked to plastics, that are on the rise (he was not concerned within the research).  (iStock)

“Many of those chemical compounds are endocrine disrupters, which might have an effect on fertility,” he advised Fox Information Digital. 

“This research is a crucial indication of that. The chance is rising as these chemical compounds are present in increasingly locations in larger quantities.”

Sure chemical compounds have larger impression

Amongst all forms of PFAS, the one which had probably the most hostile impression on fertility was perfluorodecanoic acid (PFDA). 

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PFAS (perfluoroalkyl substances) are chemicals that are often found in drinking water and ordinary household products.

PFAS (perfluoroalkyl substances) are chemical compounds which are typically present in consuming water and atypical family merchandise. (iStock)

PFDA is discovered within the atmosphere and likewise in coatings on carpets, couches and meals packaging, based on the Nationwide Library of Medication.

Different chemical compounds that affected fertility within the research had been perfluorooctanesulfonic acid (a key ingredient in stain repellents), perfluorooctanoic acid (present in Teflon and GoreTex) and perfluoroheptanoic acid (an environmental contaminant).

Risks transcend fertility impression

The research’s senior creator Dr. Damaskini Valvi, assistant professor of environmental drugs and public well being at Icahn Mount Sinai in New York Metropolis, believes that PFAS pose a number of dangers to public well being. 

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“In women and girls particularly, PFAS publicity has been additional related to delayed puberty onset, in addition to elevated threat for endometriosis, PCOS and breast most cancers, which additional helps the hostile results that PFAS have on the feminine reproductive system,” he advised Fox Information Digital in an e-mail. 

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Women with a combination of seven PFAS in their blood were 30% to 40% less likely to conceive and deliver a live birth, according to new research. 

Ladies with a mixture of seven PFAS of their blood had been 30% to 40% much less more likely to conceive and ship a reside delivery, based on new analysis.  (iStock)

PFAS have additionally been proven to extend the dangers for thyroid illnesses, excessive ldl cholesterol and blood strain, diabetes and power liver illness, in addition to sure forms of most cancers, corresponding to kidney and testicular most cancers, Dr. Valvi added.

Dr. Kelly Johnson-Arbor, medical toxicologist and interim government director on the Nationwide Capital Poison Middle in Washington, D.C., stated PFAS publicity can also be related to elevated dangers of gestational diabetes and pre-eclampsia, in addition to decreased fetal development and diminished delivery weights.

She was not concerned within the research. 

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“Since PFAS chemical compounds are recognized to cross the placenta, they will probably have an effect on the well being of each the mom and the fetus,” she advised Fox Information Digital in an e-mail. 

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‘We don’t have sufficient knowledge’

Lead research creator Dr. Valvi famous that inhabitants research within the U.S. and lots of different international locations have recognized hostile well being results from publicity to even very low quantities of PFAS.

“There’s additionally steady PFAS publicity by way of the consumption of contaminated consuming water, contaminated meals and client product use — which implies PFAS accumulates in our physique over time, probably rising our threat for power illnesses in later life,” he stated.

PFAS chemical compounds can probably have an effect on the well being of each the mom and the fetus.

“On the present time, we don’t have sufficient knowledge to inform us what a ‘secure’ degree of PFAS publicity is,” stated Dr. Johnson-Arbor. 

“There are methods to watch the degrees of PFAS in human blood, however these checks usually are not available in hospitals or medical doctors’ workplaces and are sometimes used for analysis functions solely.”

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‘Stricter laws’ wanted, say some

Dr. Valvi burdened the significance of limiting publicity to PFAS, given the well being dangers.

“Nevertheless, as a result of PFAS are broadly utilized in a number of client merchandise and we now face a worldwide contamination PFAS downside, we can’t totally keep away from publicity with out stricter laws that ban the usage of PFAS as a category,” he advised Fox Information Digital. 

“There are greater than 10,000 PFAS launched in our surroundings, however present laws think about solely 10-20 of these. That’s not sufficient.”

To avoid PFAS exposure, the study author recommends using stainless pans instead of non-stick cookware.

To keep away from PFAS publicity, the research creator recommends utilizing stainless pans as an alternative of non-stick cookware. (iStock)

“To successfully handle the PFAS downside, you will need to advocate for stronger laws that ban the presence of PFAS as a category in client merchandise and consuming water within the U.S. and globally,” Dr. Valvi continued.

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Earlier this month, the Environmental Safety Company (EPA) proposed new federal laws of PFAS chemical compounds in consuming water, which might restrict them to the bottom potential degree that may be measured.

The proposal requires limiting the PFOA and PFOS chemical compounds to 4 elements per trillion, and would additionally restrict 4 different PFAS as a mix.

Motion would “mark a serious step towards safeguarding all our communities.”

“EPA’s proposal to ascertain a nationwide commonplace for PFAS in consuming water is knowledgeable by one of the best obtainable science, and would assist present states with the steering they should make choices that greatest defend their communities,” stated Michael S. Regan, EPA administrator, in a press launch on the company’s web site. 

“This motion has the potential to forestall tens of hundreds of PFAS-related diseases and marks a serious step towards safeguarding all our communities from these harmful contaminants.”

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Suggestions for stopping PFAS publicity

“Primarily based on the outcomes of this research, it’s affordable to suggest avoidance of extreme PFAS publicity for girls who’re attempting to develop into pregnant or who’re experiencing infertility,” stated Johnson-Arbor. 

With PFAS current in all the pieces from cookware and carpets to consuming water and the air we breathe, it may be tough to fully keep away from publicity. 

Nevertheless, there are some steps individuals can take to scale back the chance.

Of all types of PFAS, the one that had the most adverse impact on fertility was perfluorodecanoic acid (PFDA), which is found in the environment and also in coatings on carpets, couches and food packaging.

Of all forms of PFAS, the one which had probably the most hostile impression on fertility was perfluorodecanoic acid (PFDA), which is discovered within the atmosphere and likewise in coatings on carpets, couches and meals packaging. (iStock)

Dr. Valvi recommends utilizing a licensed water filter that removes PFAS within the dwelling, and likewise utilizing stainless pans as an alternative of non-stick cookware.

“It’s greatest to keep away from stain-resistant and water resistant merchandise, as a result of virtually all of those merchandise comprise a number of PFAS,” he added.

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Examine co-author Dr. Nathan Cohen, a postdoctoral analysis fellow with the Division of Environmental Medication and Public Well being on the Icahn College of Medication at Mount Sinai in New York Metropolis, advised Fox Information Digital that weight-reduction plan is a quite common supply of publicity to PFAS.

PFAS are present in consuming water, in addition to on some couches, carpets, cookware and meals packaging.

“Ladies who’re planning being pregnant ought to keep away from meals which were proven to be related to elevated PFAS publicity in earlier research,” he stated. 

“These primarily embrace take-out and quick meals which are packaged in supplies which will comprise PFAS, corresponding to quick meals, popcorn and pizza. Fried meals, corresponding to fried fish, might also pose a threat and also needs to be prevented.”

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Examine had its limitations

The researchers famous that one main limitation of the research was that they didn’t have knowledge obtainable on PFAS concentrations within the male companions by way of fertility impression. 

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“We additionally didn’t have knowledge obtainable on reproductive hormones to evaluate hormone disruption as a possible mechanism,” Dr. Cohen stated. 

“Moreover, we targeted our PFAS evaluation on these detected at excessive concentrations in different populations — so we weren’t capable of assess the consequences of rising PFAS.”

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The research was funded by the Nationwide Analysis Basis through a grant from the Singapore Ministry of Well being’s Nationwide Medical Analysis Council and the Company for Science, Expertise and Analysis and the U.S. Nationwide Institute of Environmental Well being Sciences, based on the press launch from Mount Sinai.

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How Yvette Nicole Brown Lost Weight and Got Her Diabetes Under Control

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How Yvette Nicole Brown Lost Weight and Got Her Diabetes Under Control


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As bird flu spreads, CDC recommends faster 'subtyping' to catch more cases

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As bird flu spreads, CDC recommends faster 'subtyping' to catch more cases

As cases of H5N1, also known as avian flu or bird flu, continue to surface across the U.S., safety precautions are ramping up.

The U.S. Centers for Disease Control and Prevention (CDC) announced on Thursday its recommendation to test hospitalized influenza A patients more quickly and thoroughly to distinguish between seasonal flu and bird flu.

The accelerated “subtyping” of flu A in hospitalized patients is in response to “sporadic human infections” of avian flu, the CDC wrote in a press release.

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“CDC is recommending a shortened timeline for subtyping all influenza A specimens among hospitalized patients and increasing efforts at clinical laboratories to identify non-seasonal influenza,” the agency wrote.

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The CDC now recommends accelerated subtyping of influenza A in response to “sporadic human infections” in the U.S. (iStock)

“Clinicians and laboratorians are reminded to test for influenza in patients with suspected influenza and, going forward, to now expedite the subtyping of influenza A-positive specimens from hospitalized patients, particularly those in an intensive care unit (ICU).”

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The goal is to prevent delays in identifying bird flu infections and promote better patient care, “timely infection control” and case investigation, the agency stated.

These delays are more likely to occur during the flu season due to high patient volumes, according to the CDC.

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Health care systems are expected to use tests that identify seasonal influenza A as a subtype – so if a test comes back positive for influenza A but negative for seasonal influenza, that is an indicator that the detected virus might be novel.

Patient on hospital bed

Identifying bird flu infections will support better patient care and infection control, the CDC says. (iStock)

“Subtyping is especially important in people who have a history of relevant exposure to wild or domestic animals [that are] infected or possibly infected with avian influenza A (H5N1) viruses,” the CDC wrote.

In an HHS media briefing on Thursday, the CDC confirmed that the public risk for avian flu is still low, but is being closely monitored.

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The agency spokesperson clarified that this accelerated testing is not due to bird flu cases being missed, as the CDC noted in its press release that those hospitalized with influenza A “probably have seasonal influenza.”

Niels Riedemann, MD, PhD, CEO and founder of InflaRx, a German biotechnology company, said that understanding these subtypes is an “important step” in better preparing for “any potential outbreak of concerning variants.”

Blood collection tubes H5N1 in front of chicken

The CDC recommends avoiding direct contact with wild birds or other animals that may be infected. (iStock)

“It will also be important to foster research and development of therapeutics, including those addressing the patient’s inflammatory immune response to these types of viruses – as this has been shown to cause organ injury and death during the COVID pandemic,” he told Fox News Digital. 

Since 2022, there have been 67 total human cases of bird flu, according to the CDC, with 66 of those occurring in 2024.

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The CDC recommends that people avoid direct contact with wild birds or other animals that are suspected to be infected. Those who work closely with animals should also wear the proper personal protective equipment (PPE).

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Sick Prisoners in New York Were Granted Parole but Remain Behind Bars

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Sick Prisoners in New York Were Granted Parole but Remain Behind Bars

When the letter arrived at Westil Gonzalez’s prison cell saying that he had been granted parole, he couldn’t read it. Over the 33 years he had been locked up for murder, multiple sclerosis had taken much of his vision and left him reliant on a wheelchair.

He had a clear sense of what he would do once freed. “I want to give my testimony to a couple of young people who are out there, picking up guns,” Mr. Gonzalez, 57, said in a recent interview. “I want to save one person from what I’ve been through.”

But six months have passed, and Mr. Gonzalez is still incarcerated outside Buffalo, because the Department of Corrections has not found a nursing home that will accept him. Another New York inmate has been in the same limbo for 20 months. Others were released only after suing the state.

America’s elderly prison population is rising, partly because of more people serving long sentences for violent crimes. Nearly 16 percent of prisoners were over 55 in 2022, up from 5 percent in 2007. The share of prisoners over 65 quadrupled over the same time period, to about 4 percent.

Complex and costly medical conditions require more nursing care, both in prison and after an inmate’s release. Across the country, prison systems attempting to discharge inmates convicted of serious crimes often find themselves with few options. Nursing home beds can be hard to find even for those without criminal records.

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Spending on inmates’ medical care is increasing — in New York, it has grown to just over $7,500 in 2021 from about $6,000 per person in 2012. Even so, those who work with the incarcerated say the money is often not enough to keep up with the growing share of older inmates who have chronic health problems.

“We see a lot of unfortunate gaps in care,” said Dr. William Weber, an emergency physician in Chicago and medical director of the Medical Justice Alliance, a nonprofit that trains doctors to work as expert witnesses in cases involving prison inmates. With inmates often struggling to get specialty care or even copies of their own medical records, “things fall through the cracks,” he said.

Dr. Weber said he was recently involved in two cases of seriously ill prisoners, one in Pennsylvania and the other in Illinois, who could not be released without a nursing home placement. The Pennsylvania inmate died in prison and the Illinois man remains incarcerated, he said.

Almost all states have programs that allow early release for inmates with serious or life-threatening medical conditions. New York’s program is one of the more expansive: While other states often limit the policy to those with less than six months to live, New York’s is open to anyone with a terminal or debilitating illness. Nearly 90 people were granted medical parole in New York between 2020 and 2023.

But the state’s nursing home occupancy rate hovers around 90 percent, one of the highest in the nation, making it especially hard to find spots for prisoners.

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The prison system is “competing with hospital patients, rehabilitation patients and the general public that require skilled nursing for the limited number of beds available,” said Thomas Mailey, a spokesman for the New York Department of Corrections and Community Supervision. He declined to comment on Mr. Gonzalez’s case or on any other inmate’s medical conditions.

Parolees remain in the state’s custody until their original imprisonment term has expired. Courts have previously upheld the state’s right to place conditions on prisoner releases to safeguard the public, such as barring paroled sex offenders from living near schools.

But lawyers and medical ethicists contend that paroled patients should be allowed to choose how to get their care. And some noted that these prisoners’ medical needs are not necessarily met in prison. Mr. Gonzalez, for example, said he had not received glasses, despite repeated requests. His disease has made one of his hands curl inward, leaving his unclipped nails to dig into his palm.

“Although I’m sympathetic to the difficulty of finding placements, the default solution cannot be continued incarceration,” said Steven Zeidman, director of the criminal defense clinic at CUNY School of Law. In 2019, one of his clients died in prison weeks after being granted medical parole.

New York does not publish data on how many inmates are waiting for nursing home placements. One 2018 study found that, between 2013 and 2015, six of the 36 inmates granted medical parole died before a placement could be found. The medical parole process moves slowly, the study showed, sometimes taking years for a prisoner to even get an interview about their possible release.

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Finding a nursing home can prove difficult even for a patient with no criminal record. Facilities have struggled to recruit staff, especially since the coronavirus pandemic. Nursing homes may also worry about the safety risk of someone with a prior conviction, or about the financial risk of losing residents who do not want to live in a facility that accepts former inmates.

“Nursing homes have concerns and, whether they are rational or not, it’s pretty easy not to pick up or return that phone call,” said Ruth Finkelstein, a professor at Hunter College who specializes in policies for older adults and reviewed legal filings at The Times’s request.

Some people involved in such cases said that New York prisons often perform little more than a cursory search for nursing care.

Jose Saldana, the director of a nonprofit called the Release Aging People in Prison Campaign, said that when he was incarcerated at Sullivan Correctional Facility from 2010 through 2016, he worked in a department that helped coordinate parolees’ releases. He said he often reminded his supervisor to call nursing homes that hadn’t picked up the first time.

“They would say they had too many other responsibilities to stay on the phone calling,” Mr. Saldana said.

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Mr. Mailey, the spokesman for the New York corrections department, said that the agency had multiple discharge teams seeking placement options.

In 2023, Arthur Green, a 73-year-old patient on kidney dialysis, sued the state for release four months after being granted medical parole. In his lawsuit, Mr. Green’s attorneys said that they had secured a nursing home placement for him, but that it lapsed because the Department of Corrections submitted an incomplete application to a nearby dialysis center.

The state found a placement for Mr. Green a year after his parole date, according to Martha Rayner, an attorney who specializes in prisoner release cases.

John Teixeira was granted medical parole in 2020, at age 56, but remained incarcerated for two and a half years, as the state searched for a nursing home. He had a history of heart attacks and took daily medications, including one delivered through an intravenous port. But an assessment from an independent cardiologist concluded that Mr. Teixeira did not need nursing care.

Lawyers with the Legal Aid Society in New York sued the state for his release, noting that during his wait, his port repeatedly became infected and his diagnosis progressed from “advanced” to “end-stage” heart failure.

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The Department of Corrections responded that 16 nursing homes had declined to accept Mr. Teixeira because they could not manage his medical needs. The case resolved three months after the suit was filed, when “the judge put significant pressure” on the state to find an appropriate placement, according to Stefen Short, one of Mr. Teixeira’s lawyers.

Some sick prisoners awaiting release have found it difficult to get medical care on the inside.

Steve Coleman, 67, has trouble walking and spends most of the day sitting down. After 43 years locked up for murder, he was granted parole in April 2023 and has remained incarcerated, as the state looks for a nursing home that could coordinate with a kidney dialysis center three times each week.

But Mr. Coleman has not had dialysis treatment since March, when the state ended a contract with its provider. The prison has offered to take Mr. Coleman to a nearby clinic for treatment, but he has declined because he finds the transportation protocol — which involves a strip search and shackles — painful and invasive.

“They say you’ve got to go through a strip search,” he said in a recent interview. “If I’m being paroled, I can’t walk and I’m going to a hospital, who could I be hurting?”

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Volunteers at the nonprofit Parole Prep Project, which assisted Mr. Coleman with his parole application, obtained a letter from Mount Sinai Hospital in New York City in June offering to give him medical care and help him transition back into the community.

Still incarcerated two months later, Mr. Coleman sued for his release.

In court filings, the state argued that it would be “unsafe and irresponsible” to release Mr. Coleman without plans to meet his medical needs. The state also said that it had contacted Mount Sinai, as well as hundreds of nursing homes, about Mr. Coleman’s placement and had never heard back.

In October, a court ruled in the prison system’s favor. Describing Mr. Coleman’s situation as “very sad and frustrating,” Justice Debra Givens of New York State Supreme Court concluded that the state had a rational reason to hold Mr. Coleman past his parole date. Ms. Rayner, Mr. Coleman’s lawyer, and the New York Civil Liberties Union appealed the ruling on Wednesday.

Fourteen medical ethicists have sent a letter to the prison supporting Mr. Coleman’s release. “Forcing continued incarceration under the guise of ‘best interests,’ even if doing so is well-intentioned, disregards his autonomy,” they wrote.

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Several other states have come up with a different solution for people on medical parole: soliciting the business of nursing homes that specialize in housing patients rejected elsewhere.

A private company called iCare in 2013 opened the first such facility in Connecticut, which now houses 95 residents. The company runs similar nursing homes in Vermont and Massachusetts.

David Skoczulek, iCare’s vice president of business development, said that these facilities tend to save states money because the federal government covers some of the costs through Medicaid.

“It’s more humane, less restrictive and cost-effective,” he said. “There is no reason for these people to remain in a corrections environment.”

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