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Column: The COVID lab-leak claim isn't just an attack on science, but a threat to public health

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Column: The COVID lab-leak claim isn't just an attack on science, but a threat to public health

Here’s an indisputable fact about the theory that COVID originated in a laboratory: Most Americans believe it to be true.

That’s important for several reasons. One is that evidence to support the theory is nonexistent. Another is that the claim itself has fomented a surge of attacks on science and scientists that threatens to drive promising researchers out of the crucial field of pandemic epidemiology.

That concern was aired in a commentary by 41 biologists, immunologists, virologists and physicians published Aug. 1 in the Journal of Virology. The journal probably isn’t in the libraries of ordinary readers, but the article’s prose is commendably clear and its conclusions eye-opening.

We now see a long-term risk of having fewer experts engaged in work that may help thwart future pandemics, and of fewer scientists willing to communicate the findings of sophisticated, fast-moving research topics that are important for global health.

— 41 scientists warn of the rise in anti-science disinformation

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“The lab leak narrative fuels mistrust in science and public health infrastructures,” the authors observe. “Scientists and public health professionals stand between us and pandemic pathogens; these individuals are essential for anticipating, discovering, and mitigating future pandemic threats. Yet, scientists and public health professionals have been harmed and their institutions have been damaged by the skewed public and political opinions stirred by continued promotion of the lab leak hypothesis in the absence of evidence.”

Before exploring further how the lab leak theory has been exploited to undermine public confidence in science and scientists, let’s examine what’s known and unknown about the origins of SARS-CoV-2, the virus that causes COVID.

The so-called zoonosis hypothesis, which is favored by the vast majority of the virological and epidemiological communities, is that the virus reached humans via a spillover from the animal kingdom, probably through the unregulated wildlife trade in Southeast Asia.

“Validating the zoonotic origin is a scientific question that relies on history, epidemiology, and genomic analysis, that when taken together, support a natural spillover as the probable origin,” the Virology paper states.

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The lab leak theory holds that SARS-2 was created or manipulated into existence in the Wuhan Institute of Virology and escaped from the lab, whether deliberately or by accident.

Lab leak adherents bristle at the accusation that they’re conspiracy-mongers. Anthony Fauci, the retired director of the National Institute of Allergy and Infectious Diseases and the target of some of the most febrile attacks from the anti-science crowd, acknowledged at a June 3 House hearing that the lab leak theory was not inherently a conspiracy theory, conceptually—but that it had been exploited to support some truly crazy conspiracy narratives.

Fauci testified that he remained open to a lab leak narrative in principle, and that if any evidence for it emerged he would consider it seriously. That’s typical of most scientists, especially biologists, who are led by the infinite variability of the natural world to be innately averse to declaring anything conclusively possible or impossible.

The fact is, however, that one can’t advance the lab leak theory without positing a vast conspiracy encompassing scientists in China and the U.S., and Chinese and U.S. government officials. How else could all the evidence of a laboratory event that resulted in more than 7 million deaths worldwide be kept entirely suppressed for nearly five years? Some external hint of the event inevitably would have surfaced somewhere, somehow, by now. None has.

“Validating the lab leak hypothesis requires intelligence evidence that the WIV possessed or carried out work on a SARS-CoV-2 precursor virus prior to the pandemic,” the Virology paper asserts. “Neither the scientific community nor multiple western intelligence agencies have found such evidence.”

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Despite that, “the lab leak hypothesis receives persistent attention in the media, often without acknowledgment of the more solid evidence supporting zoonotic emergence,” the paper says. The paper doesn’t name all the media culprits, but they include the independent investigative news site ProPublica and Vanity Fair.

It does take direct aim, however, at the New York Times, which on June 3 published a column by researcher Alina Chan asserting that the “pandemic probably started in a lab.” In a 2021 book, Chan had aired almost identical arguments that were largely refuted by experts in the field. Her more recent article “misrepresents and underplays the existing scientific data supporting a zoonotic origin of SARS-CoV-2,” the Virology paper reported.

I’ve written before about the smears, physical harassment and baseless accusations of fraud and other wrongdoing that lab leak propagandists have visited upon scientists whose work has challenged their claims; similar attacks have targeted experts who have worked to debunk other anti-science narratives, including those about global warming and vaccines.

Some of these attacks have come from elected officials seeking partisan cred, such as Sen. Rand Paul (R-Ky.) and Rep. Marjorie Taylor Greene (R-Ga.). They’ve been augmented by figures such as Donald Trump and Robert F. Kennedy Jr.

What’s notable about the Virology paper is that it represents a comprehensive and long-overdue pushback by the scientific community against such behavior. More to the point, it focuses on the consequences for public health and the scientific mission from the rise of anti-science propaganda.

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Its authors are drawn from the faculties of the state universities of Arizona, California, Connecticut, Maryland, Florida and Ohio, as well as from Johns Hopkins, Duke and the Cleveland Clinic.

“Scientists have withdrawn from social media platforms, rejected opportunities to speak in public, and taken increased safety measures to protect themselves and their families,” the authors report.

“Some have even diverted their work to less controversial and less timely topics. We now see a long-term risk of having fewer experts engaged in work that may help thwart future pandemics, and of fewer scientists willing to communicate the findings of sophisticated, fast-moving research topics that are important for global health….Most worrisome for future preparedness, the next generation of scientists has well-founded fears about entering fields related to emerging viruses and pandemic science.”

The paper revisits the scene at the public interrogation by House Republicans on June 3. “The hearing,” it observes, “was often disrupted and marked by contentious, disrespectful, and unfounded calls for Dr. Fauci to be ‘prosecuted’ and imprisoned for ‘crimes against humanity.’”

By presupposing that evidence of a lab leak has been deliberately suppressed by leading scientists and scientific administrators, its promoters have cast “unsupported blame on scientists, many of whom had warned of the potential threat of, and need for effective countermeasures to prevent, zoonotic transfer of viruses into humans,” the authors write.

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At a certain level, the popular embrace of scientific conspiracy theories is understandable. As the Swiss molecular biologist and science writer Philipp Markolin has observed, disinformation relies on myths that provide simple explanations for traumatic world events, like the pandemic, by positing that it was caused by shadowy, powerful actors. There’s never a shortage of grifters and manipulators using this public confusion to their advantage.

Thanks in part to social media, anti-science has become more virulent and widespread, the Virology authors write. Large numbers of researchers into SARS-2 have reported “harassment ranging from personal insults to threats of violence, ‘doxing,’ and personal contact,” according to the paper— of 1,281 scientists in several fields who responded to a survey by Science, 51% said they had experienced at least one form of harassment, sometimes over a period of years.

The Virology authors warn that the vilification of scientists whose research supports the zoonosis hypothesis will leave society defenseless when the next pandemic threat emerges.

“If these narratives are left unchecked, we become a society that dismisses and vilifies those with expertise and experience relevant to the challenges we face,” the authors write. “We then base decisions affecting large populations worldwide on speculation or chosen beliefs that have no grounding in evidence-based science.”

That’s what the future holds if we allow misinformation and disinformation, weaponized by sociopaths seeking financial or partisan gain, to guide our actions. We have been warned.

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How our AI bots are ignoring their programming and giving hackers superpowers

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How our AI bots are ignoring their programming and giving hackers superpowers

Welcome to the age of AI hacking, in which the right prompts make amateurs into master hackers.

A group of cybercriminals recently used off-the-shelf artificial intelligence chatbots to steal data on nearly 200 million taxpayers. The bots provided the code and ready-to-execute plans to bypass firewalls.

Although they were explicitly programmed to refuse to help hackers, the bots were duped into abetting the cybercrime.

According to a recent report from Israeli cybersecurity firm Gambit Security, hackers last month used Claude, the chatbot from Anthropic, to steal 150 gigabytes of data from Mexican government agencies.

Claude initially refused to cooperate with the hacking attempts and even denied requests to cover the hackers’ digital tracks, the experts who discovered the breach said. The group pummelled the bot with more than 1,000 prompts to bypass the safeguards and convince Claude they were allowed to test the system for vulnerabilities.

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AI companies have been trying to create unbreakable chains on their AI models to restrain them from helping do things such as generating child sexual content or aiding in sourcing and creating weapons. They hire entire teams to try to break their own chatbots before someone else does.

But in this case, hackers continuously prompted Claude in creative ways and were able to “jailbreak” the chatbot to assist them. When they encountered problems with Claude, the hackers used OpenAI’s ChatGPT for data analysis and to learn which credentials were required to move through the system undetected.

The group used AI to find and exploit vulnerabilities, bypass defences, create backdoors and analyze data along the way to gain control of the systems before they stole 195 million identities from nine Mexican government systems, including tax records, vehicle registration as well as birth and property details.

AI “doesn’t sleep,” Curtis Simpson, chief executive of Gambit Security, said in a blog post. “It collapses the cost of sophistication to near zero.”

“No amount of prevention investment would have made this attack impossible,” he said.

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Anthropic did not respond to a request for comment. It told Bloomberg that it had banned the accounts involved and disrupted their activity after an investigation.

OpenAI said it is aware of the attack campaign carried out using Anthropic’s models against the Mexican government agencies.

“We also identified other attempts by the adversary to use our models for activities that violate our usage policies; our models refused to comply with these attempts,” an OpenAI spokesperson said in a statement. “We have banned the accounts used by this adversary and value the outreach from Gambit Security.”

Instances of generative AI-assisted hacking are on the rise, and the threat of cyberattacks from bots acting on their own is no longer science fiction. With AI doing their bidding, novices can cause damage in moments, while experienced hackers can launch many more sophisticated attacks with much less effort.

Earlier this year, Amazon discovered that a low-skilled hacker used commercially available AI to breach 600 firewalls. Another took control of thousands of DJI robot vacuums with help from Claude, and was able to access live video feed, audio and floor plans of strangers.

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“The kinds of things we’re seeing today are only the early signs of the kinds of things that AIs will be able to do in a few years,” said Nikola Jurkovic, an expert working on reducing risks from advanced AI. “So we need to urgently prepare.”

Late last year, Anthropic warned that society has reached an “inflection point” in AI use in cybersecurity after disrupting what the company said was a Chinese state-sponsored espionage campaign that used Claude to infiltrate 30 global targets, including financial institutions and government agencies.

Generative AI also has been used to extort companies, create realistic online profiles by North Korean operatives to secure jobs in U.S. Fortune 500 companies, run romance scams and operate a network of Russian propaganda accounts.

Over the last few years, AI models have gone from being able to manage tasks lasting only a few seconds to today’s AI agents working autonomously for many hours. AI’s capability to complete long tasks is doubling every seven months.

“We just don’t actually know what is the upper limit of AI’s capability, because no one’s made benchmarks that are difficult enough so the AI can’t do them,” said Jurkovic, who works at METR, a nonprofit that measures AI system capabilities to cause catastrophic harm to society.

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So far, the most common use of AI for hacking has been social engineering. Large language models are used to write convincing emails to dupe people out of their money, causing an eight-fold increase in complaints from older Americans as they lost $4.9 billion in online fraud in 2025.

“The messages used to elicit a click from the target can now be generated on a per-user basis more efficiently and with fewer tell-tale signs of phishing,” such as grammatical and spelling errors, said Cliff Neuman, an associate professor of computer science at USC.

AI companies have been responding using AI to detect attacks, audit code and patch vulnerabilities.

“Ultimately, the big imbalance stems from the need of the good-actors to be secure all the time, and of the bad-actors to be right only once,” Neuman said.

The stakes around AI are rising as it infiltrates every aspect of the economy. Many are concerned that there is insufficient understanding of how to ensure it cannot be misused by bad actors or nudged to go rogue.

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Even those at the top of the industry have warned users about the potential misuse of AI.

Dario Amodei, the CEO of Anthropic, has long advocated that the AI systems being built are unpredictable and difficult to control. These AIs have shown behaviors as varied as deception and blackmail, to scheming and cheating by hacking software.

Still, major AI companies — OpenAI, Anthropic, xAI, and Google — signed contracts with the U.S. government to use their AIs in military operations.

This last week, the Pentagon directed federal agencies to phase out Claude after the company refused to back down on its demand that it wouldn’t allow its AI to be used for mass domestic surveillance and fully autonomous weapons.

“The AI systems of today are nowhere near reliable enough to make fully autonomous weapons,” Amodei told CBS News.

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iPic movie theater chain files for bankruptcy

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iPic movie theater chain files for bankruptcy

The iPic dine-in movie theater chain has filed for Chapter 11 bankruptcy protection and intends to pursue a sale of its assets, citing the difficult post-pandemic theatrical market.

The Boca Raton, Fla.-based company has 13 locations across the U.S., including in Pasadena and Westwood, according to a Feb. 25 filing in U.S. Bankruptcy Court in the Southern District of Florida, West Palm Beach division.

As part of the bankruptcy process, the Pasadena and Westwood theaters will be permanently closed, according to WARN Act notices filed with the state of California’s Employment Development Department.

The company came to its conclusion after “exploring a range of possible alternatives,” iPic Chief Executive Patrick Quinn said in a statement.

“We are committed to continuing our business operations with minimal impact throughout the process and will endeavor to serve our customers with the high standard of care they have come to expect from us,” he said.

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The company will keep its current management to maintain day-to-day operations while it goes through the bankruptcy process, iPic said in the statement. The last day of employment for workers in its Pasadena and Westwood locations is April 28, according to a state WARN Act notice. The chain has 1,300 full- and part-time employees, with 193 workers in California.

The theatrical business, including the exhibition industry, still has not recovered from the pandemic’s effect on consumer behavior. Last year, overall box office revenue in the U.S. and Canada totaled about $8.8 billion, up just 1.6% compared with 2024. Even more troubling is that industry revenue in 2025 was down 22.1% compared with pre-pandemic 2019’s totals.

IPic noted those trends in its bankruptcy filing, describing the changes in consumer behavior as “lasting” and blaming the rise of streaming for “fundamentally” altering the movie theater business.

“These industry shifts have directly reduced box office revenues and related ancillary revenues, including food and beverage sales,” the company stated in its bankruptcy filing.

IPic also attributed its decision to rising rents and labor costs.

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The company estimated it owed about $141,000 in taxes and about $2.7 million in total unsecured claims. The company’s assets were valued at about $155.3 million, the majority of which coming from theater equipment and furniture. Its liabilities totaled $113.9 million.

The chain had previously filed for bankruptcy protection in 2019.

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Startup Varda Space Industries snags former Mattel plant in El Segundo

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Startup Varda Space Industries snags former Mattel plant in El Segundo

In an expansion of its business of processing pharmaceuticals in Earth’s orbit, Varda Space Industries is renting a large El Segundo plant where toy manufacturer Mattel used to design Hot Wheels and Barbie dolls.

The plant in El Segundo’s aerospace corridor will be an extension of Varda Space Industries’ headquarters in a much smaller building on nearby Aviation Boulevard.

Varda will occupy a 205,443-square-foot industrial and office campus at 2031 E. Mariposa Ave., which will give it additional capacity to manufacture spacecraft at scale, the company said.

Originally built in the 1940s as an aircraft facility, the complex has a history as part of aerospace and defense industries that have long shaped the South Bay and is near a host of major defense and space contractors. It is also close to Los Angeles Air Force Base, headquarters to the Space Systems Command.

Workers test AstroForge’s Odin asteroid probe, which was lost in space after launch this year.

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(Varda Space Industries)

Varda is one of a new generation of aerospace startups that have flourished in Southern California and the South Bay over the last several years, particularly in El Segundo, often with ties to SpaceX.

Elon Musk’s company, founded in 2002 in El Segundo, has revolutionized the industry with reusable rockets that have radically lowered the cost of lifting payloads into space. Though it has moved its headquarters to Texas, SpaceX retains large-scale operations in Hawthorne.

Varda co-founder and Chief Executive Will Bruey is a former SpaceX avionics engineer, and the company’s spacecraft are launched on SpaceX’s workhorse Falcon 9 rockets from Vandenberg Space Force Base in Santa Barbara County.

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Varda makes automated labs that look like cylindrical desktop speakers, which it sends into orbit in capsules and satellite platforms it also builds. There, in microgravity, the miniature labs grow molecular crystals that are purer than those produced in Earth’s gravity for use in pharmaceuticals.

It has contracts with drug companies and also the military, which tests technology at hypersonic speeds as the capsules return to Earth.

Its fifth capsule was launched in November and returned to Earth in late January; its next mission is set in the coming weeks. Varda has more than 10 missions scheduled on Falcon 9s through 2028.

For the last several decades, the Mariposa Avenue property served as the research and development center for Mattel Toys. El Segundo has also long been a center for the toy industry as companies like to set up shop in the shadow of Mattel.

The Mattel facility “has always been an exceptional property with a legacy tied to aerospace innovation, and leasing to Varda Space Industries feels like a natural continuation of that story,” said Michael Woods, a partner at GPI Cos., which owns the property.

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“We are proud to support a company that is genuinely pushing the boundaries of what’s possible, and are excited to watch Varda grow and thrive here in El Segundo,” Woods said.

As one of the country’s most active hubs of aerospace and defense innovation, El Segundo has seen its industrial property vacancy fall to 3.4% on demand from space companies, government contractors and technology startups, real estate brokerage CBRE said.

Successful startups often have to leave the neighborhood when they want to expand, real estate broker Bob Haley of CBRE said. The 9-acre Mattel facility was big enough to keep Varda in the city.

Last year, Varda subleased about 55,000 square feet of lab space from alternative protein company Beyond Meat at 888 Douglas St. in El Segundo, which it started moving into in June.

Varda will get the keys to its new building in December and spend four to eight months building production and assembly facilities as it ramps up operations. By the end of next year, it expects to have constructed 10 more spacecraft.

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In the future, Varda could consolidate offices there, given its size. Currently, though, the plan is to retain all properties, creating a campus of three buildings within a mile of one another that are served by the company’s transportation services, Chief Operating Officer Jonathan Barr said.

“We already have Varda-branded shuttles running up and down Aviation Boulevard,” he said.

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