Science
Susan F. Wood, Who Quit F.D.A. Over Contraception Pill Delay, Dies at 66
Susan F. Wood, a women’s health expert who resigned in protest from the Food and Drug Administration in 2005, accusing the agency of knuckling under to politics by not approving over-the-counter sales of the morning-after pill known as Plan B, died on Jan. 17 at her home in London. She was 66.
The cause was the brain cancer glioblastoma multiforme, said Richard Payne, her husband.
Dr. Wood was assistant commissioner for women’s health at the F.D.A. during the presidency of George W. Bush when Plan B, a form of emergency contraception, became a flashpoint in the abortion wars.
An F.D.A. advisory panel voted 28-0 in 2003 that the pill was safe for nonprescription use. But senior agency officials disregarded precedent and refused to approve over-the-counter sales.
Plan B contains high levels of progestin, a hormone found in ordinary birth control pills, and agency scientists considered it to be a contraceptive. But abortion opponents argued that its use was tantamount to ending pregnancies. They further warned that ready access would lead to promiscuous behavior by teenagers, though no data supported that claim.
Dr. Wood and others believed that having emergency contraception available without a prescription would mean fewer unwanted pregnancies and fewer abortions.
In August 2005, the F.D.A. commissioner, Lester M. Crawford, announced that the agency could not reach a decision on whether to authorize over-the-counter use of Plan B and did not expect to reach one soon.
Dr. Wood blamed politics for the agency’s foot-dragging and resigned from a job she had held for five years. In an email to the staff, she wrote that she could no longer remain “when scientific and clinical evidence, fully evaluated and recommended for approval by the professional staff here, has been overruled.”
A report later that year by the Government Accountability Office, the nonpartisan investigative arm of Congress, found that top agency officials had rejected over-the-counter sales even before the scientific review of Plan B was complete. Officials disputed the findings.
Dr. Wood addressed the American Association for the Advancement of Science in 2006 and received a standing ovation. She criticized the F.D.A. for ignoring science because “social conservatives have extreme undue influence.”
Susan Franklin Wood was born on Nov. 5, 1958, in Jacksonville, Fla., one of four children of Dr. Jonathan Wood, a surgeon, and Betty (Dorscheid) Wood.
She graduated from the Episcopal School of Jacksonville in 1976 and Southwestern at Memphis (now Rhodes College) in 1980. After earning a Ph.D. in biology from Boston University in 1989, she shifted her focus to health policy.
In 1990, she received a fellowship as a science adviser to the Congressional Caucus for Women’s Issues, a bipartisan group. Over five years on Capitol Hill, she helped push legislation to increase the representation of women in clinical trials and to expand research into breast cancer, infertility and contraception.
In 1995 she became policy director in the Office on Women’s Health, part of the Department of Health and Human Services. She joined the F.D.A. in 2000 to lead the women’s health department.
Objections to approving Plan B for over-the-counter sales zeroed in on whether it should be available to younger teenagers. The manufacturer, Barr Laboratories, proposed restricting sales to people 16 and up.
A senior F.D.A. official told Dr. Wood that the drug was on track to win nonprescription approval for those 17 and older, Dr. Wood recalled in an oral history that she recorded for the agency in 2019.
“I heard that with my own little ears,” she said. “And everyone was waiting for the decision to come out, silently.”
“But,” she added, “the decision never came out.”
On a Friday afternoon, Dr. Crawford announced that an age restriction for over-the-counter sales would be hard for pharmacies to manage. The issue, he said, needed more study. In the meantime, nonprescription use was not approved for anyone.
Dr. Wood quit the next Tuesday. She expected her decision to go mostly unnoticed. Instead, the news media instantly reported on it.
“I ended up spending the next eight months really just traveling and speaking about this,” she said. “It affected the perception of whether or not you could trust government at the time.”
In 2006, Dr. Wood joined the Milken Institute School of Public Health at George Washington University as a research professor. She became a full professor in 2017 and directed the Jacobs Institute of Women’s Health there. She and her husband moved to the Isle of Mull in Scotland in 2017, with a second residence in London; she continued to teach remotely until she retired in 2022.
Besides her husband, she is survived by a daughter, Bettie Wood Payne.
The contretemps over Plan B faded, overshadowed by more contentious episodes of abortion politics. Plan B finally won over-the-counter approval in 2013, though some states allow pharmacists to refuse to dispense it.
In 2019, Dr. Wood said fears that easy access to a morning-after pill would be a “dangerous, radical, crazy” thing proved to be overblown.
“Once it’s over the counter, it’s no big deal,” she said. “And, sure enough, that’s what happened. It’s no big deal.”
Science
China Launches Reusable Rocket in Race With SpaceX
Video released by Chinese state media shows a state-owned aerospace company launching a rocket and recovering part of it on Friday. The successful launch of a reusable rocket was a major step for China toward challenging SpaceX’s satellite internet dominance.
Science
Nobel Prize winner leaving UC Berkeley for new role in China
Nobel Prize recipient Omar Yaghi is leaving his role at UC Berkeley to lead the development of a new artificial intelligence institute at Tsinghua University in Beijing, the Chinese university announced.
Yaghi will head the AI Chemistry and Materials Research Institute at Tsinghua, where he was appointed an honorary professor in 2022. Known as AIMATRY (AI × Materials × Chemistry), the new center will focus on material design and synthesis through artificial intelligence, according to a statement from the university.
In 2025, Yaghi shared the Nobel Prize in chemistry with Susumu Kitagawa of Kyoto University and Richard Robson of the University of Melbourne for their development of metal-organic frameworks, a type of super-porous material in which metal ions and carbon-based molecules combine to form crystals with exceptionally large surface areas.
The material has the potential to combat climate change by capturing and storing carbon or other pollutants, and by extracting water from the atmosphere in water-scarce areas. Upon awarding the prize, a member of the Nobel committee likened the technology’s ability to store enormous amounts of stuff in seemingly compact spaces to Hermione Granger’s enchanted handbag in the Harry Potter series.
Yaghi’s Irvine-based company, Atoco, has said it will start taking orders later this year for its technology that harvests water from the air.
A representative for Yaghi said he was not yet available to respond to questions.
China is one of several countries that has been actively recruiting scientists from the U.S., where the Trump administration has slashed science funding, suspended research grants, fired science advisors and tightened immigration restrictions.
“For many, many years, our funding was very competitive; if you worked hard and you were doing good research, you would get funding,” Yaghi said of the U.S. in an interview with Scientific American earlier this year. “The current state is not so encouraging because of the cutting back on grants and support of science by the very agencies that many university researchers rely on.”
Yaghi was born in Jordan to Palestinian refugees, and immigrated to the U.S. when he was 15 to study.
“We’ve learned over and over in human civilization that scholars can move across borders,” Yaghi told the New York Times last year. “This is how knowledge spread and how vast regions of the world lifted themselves out of poverty.”
Science
Trump administration seeks to limit federal funding that doesn’t ‘advance’ presidential policies
A new rule proposed by the White House Office of Management and Budget would fundamentally overhaul the way federal grants are awarded and overseen — a sweeping change that one scientific society said “would all but end the use of scientific merit in the selection of grants and programs across the government.”
Proposed in late May, the rule would give political appointees unprecedented control over federal grants for research, education and infrastructure, and specifies that government funds can only be spent on projects “aligned with administration policies and priorities,” according to a copy of the proposed rule.
The rule would also restrict research topics, limit U.S. scientists’ ability to collaborate with colleagues in other countries and make it easier for the government to suspend or cancel grants at any time.
The changes are intended to improve “transparency, accountability, and oversight for Federal awards” while “ensuring that American tax dollars are not wasted or misused,” according to the White House office.
But critics say that if the rule is implemented, the final sign-off for grants will no longer be in the hands of subject-matter experts within individual agencies, but in those of political appointees.
“This touches all parts of American life,” said Dr. Eric Rafla-Yuan, a psychiatrist who practices at the Veterans Administration and San Diego County’s psychiatric hospital.
“Control of how all of the federal grants and programs are funded will fall under a small group of highly partisan individuals who would have very few limits on how they spend these billions of taxpayer dollars,” said Rafla-Yuan, who also chairs the Committee to Protect Public Mental Health advocacy group. “This touches everyone’s life, even if they don’t realize it.”
OMB published the proposed rule May 29, opening a 45-day comment period that closes July 13.
Opposition to the proposed rule has mobilized multiple sectors of society. Professional groups representing cancer researchers, civil engineers, county governments, medical schools, housing agencies, city and municipal governments, nonprofits and others have publicly expressed concerns about potential consequences.
By midday Thursday, the Federal Register logged nearly 100,000 comments about the proposal, many of them expressing concern.
“I understand the need for oversight, fiscal responsibility, and accountability. That is not the issue,” wrote Jack Feldman, a neuroscientist who holds the David Geffen School of Medicine Chair in Neuroscience at UCLA. “The issue is whether scientific research is to be judged by scientific merit, or whether it can be approved, denied, or terminated according to broad political criteria that may change from one administration to the next.”
Crucially, the rule converts policies governing federal grants from “guidance” into binding regulations that all agencies would be required to follow. It would give political appointees power to override federal agencies’ merit-based reviews and mandate that a political appointee review decisions to ensure that all awards “demonstrably advance the President’s policy priorities.”
The elevation of political appointees in what were previously merit-based decisions has alarmed many scientists.
“The proposed rule changes would all but end the use of scientific merit in the selection of grants and programs across the government,” read a statement from the Planetary Society, a nonprofit dedicated to space research.
Researchers and science groups have also expressed concern about a section of the rule prohibiting the promotion of “theories of disparate-impact liability” — a legal concept that refers to policies that appear neutral but cause disproportionate harm to certain groups.
The section’s vague language and many loopholes could have a chilling effect on any research that studies the effects of a disease, policy or public health intervention on any specific group of people, Rafla-Yuan said.
As an example, he said, “if there’s a specific age range that is at higher risk for suicide, and we want to figure out, well, what’s going on with people that are aged 14 to 19 … we can’t do that under the wording in this rule.”
New restrictions on collaborations with scientists in other countries would hinder opportunities for U.S. researchers and limit innovation, said Joanne Padrón Carney, chief government relations officer for the American Assn. for the Advancement of Science.
“Science is a global enterprise. Especially in biomedical and public health fields, diseases don’t care about borders or government policies,” she said.
California’s congressional delegation sent a letter Wednesday asking OMB to rescind the proposal, outlining concerns about its impact on scientific innovation, U.S. competitiveness and the fiscal stability of local governments, many of which rely on federal grants for local services.
The proposed rule grants the federal government broad powers to suspend or cancel grants for any reason, introducing “unprecedented unpredictability into local governance,” the lawmakers wrote, “leaving vital infrastructure projects unfinished and abandoning vulnerable populations who rely on these services.”
Republican Sen. Susan Collins has also asked the White House to withdraw certain parts of the letter and extend the public comment period, saying the proposed rule as written would “harm small and rural communities, undermine scientific and biomedical research, and conflict with Congress’ control over the federal funding process.”
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