Connect with us

Science

High Demand for Drug to Prevent Covid in the Vulnerable, Yet Doses Go Unused

Published

on

High Demand for Drug to Prevent Covid in the Vulnerable, Yet Doses Go Unused

Sasha Mallett, Sue Taylor and Kimberly Cooley all have immune deficiencies that make them particularly susceptible to Covid-19, and all have tried to get the identical factor: a brand new therapy that may forestall the illness in individuals who both can’t produce antibodies after receiving a coronavirus vaccine or can’t get vaccinated in any respect.

Ms. Cooley, a liver transplant recipient in Duck Hill, Miss., obtained the antibody drug, known as Evusheld, from her transplant crew on the College of Mississippi Medical Heart with no hassle. However Ms. Taylor, of Cincinnati, was denied the therapy by two hospitals close to her house. And Dr. Mallett, a doctor in Portland, Ore., needed to drive 5 hours to a hospital prepared to present her a dose.

As a lot of the nation unmasks amid plummeting caseloads and contemporary hope that the pandemic is fading, the Biden administration has insisted it should proceed defending the greater than seven million Individuals with weakened immune methods who stay susceptible to Covid. Evusheld, which was developed by AstraZeneca with monetary assist from the federal authorities, is crucial to its technique.

However there may be a lot confusion in regards to the drug amongst well being care suppliers that roughly 80 p.c of the accessible doses are sitting unused in warehouses and on pharmacy and hospital cabinets — whilst sufferers like Ms. Taylor, 67, and Dr. Mallett, 38, go to nice lengths, usually with out success, to get them.

As a result of they’ve a weakened response to the coronavirus vaccine and should not be capable to battle off Covid-19, many immunocompromised folks have continued to isolate themselves at house and really feel left behind because the nation reopens. Evusheld, which is run in two consecutive injections, seems to supply long-lasting safety — maybe for half a 12 months — giving it appreciable enchantment for this group.

Advertisement

For now, although, the drug is in brief provide. As a result of it’s approved just for emergency use, it’s being distributed by the federal authorities. The Biden administration has bought 1.7 million doses — sufficient to completely deal with 850,000 folks — and had almost 650,000 doses prepared for distribution to the states as of this previous week, based on a senior federal well being official. However solely about 370,000 doses have been ordered by the states, and fewer than 1 / 4 of these have been used.

“There’s so many different people who find themselves scrapping and driving for hours to get Evusheld,” Ms. Cooley, 40, mentioned, “when in Mississippi it’s sitting on the cabinets.”

Interviews with medical doctors, sufferers and authorities officers counsel the explanations the drug goes unused are assorted. Some sufferers and medical doctors have no idea Evusheld exists. Some have no idea the place to get it. Authorities pointers on who ought to be prioritized for the drug are scant. In some hospitals and medical facilities, provides are being reserved for sufferers on the highest threat, reminiscent of latest transplant recipients and most cancers sufferers, whereas doses in different areas of the nation are being given out by means of a lottery or on a first-come, first-served foundation.

Hesitance can be a difficulty. Some medical doctors and different suppliers have no idea learn how to use Evusheld and are thus loath to prescribe it. The truth that it’s an antibody therapy will be complicated, as a result of most such remedies are used after somebody will get Covid quite than for preventive care.

Including to the confusion are revised Meals and Drug Administration pointers for Evusheld, launched final month, that known as for doubling the preliminary really useful dose after information confirmed the drug could also be much less efficient towards sure variants.

Advertisement

“It’s overwhelming and it’s all new,” mentioned Dr. Mitchell H. Grayson, chief of the allergy and immunology division at Nationwide Kids’s Hospital in Columbus, Ohio. “Suppliers are undoubtedly making an attempt to maintain up, it’s simply — I don’t understand how properly everybody’s doing with that.”

Roughly 3 p.c of Individuals are characterised by well being professionals as immunocompromised as a result of they’ve a illness that weakens their physique’s immune response or are receiving a therapy that does so. They embrace transplant recipients and folks with circumstances like most cancers, lupus and rheumatoid arthritis.

Evusheld’s arrival in December instantly set off a scramble. In Fb teams and on-line messages, sufferers and their family members started swapping details about learn how to get it. Authorities information units about Evusheld’s availability have been so advanced and complicated {that a} software program developer within the Seattle space, Rob Relyea, developed his personal mapping instrument that tracks how a lot of the drug is accessible and which suppliers have it.

“Individuals ought to know the place to go to get in line,” he mentioned.

Mr. Relyea, 51, had a vested curiosity: His spouse, Rebecca, is in remission from most cancers. They tried 10 hospitals unsuccessfully however then obtained the drug by means of luck, as Ms. Relyea’s identify was picked in a lottery for Evusheld at a hospital close to their house in early February, he mentioned.

Advertisement

However they haven’t heard something but about scheduling a second dose, which Ms. Relyea wants primarily based on the brand new suggestions.

Dr. Mallett, in Oregon, was one in all many who have been determined to get the drug. She has frequent variable immunodeficiency, a situation that retains her immune system from making sufficient antibodies. Her son began attending kindergarten in individual final fall, and when the Omicron variant surged, his instructor and classmates started testing constructive for Covid.

To seek out Evusheld, Dr. Mallett scoured a web based authorities database of shipments and spent weeks cold-calling hospitals, pharmacies and well being organizations that acquired the drug.

Advertisement

When she lastly discovered a hospital in La Grande, Ore., prepared to present her a dose, she labored together with her doctor to enroll as a affected person there. Then she dropped the whole lot and drove to the hospital within the rain, acquired the pictures and instantly turned again — an 11-hour journey in whole.

Dr. Mallett is extremely educated, medically savvy, rich and simply capable of take time away from her job — privileges that helped her get a dose, however that many others don’t have.

“I undoubtedly have lots of lingering moral qualms about how I went about getting this remedy,” she mentioned. “Did I make the most of our damaged system?”

Most of the well being staff Dr. Mallett known as whereas she was looking for a dose had not even heard of Evusheld — even when their workplaces had the drug in inventory.

Some consultants argue that Evusheld ought to go first to individuals who can’t get vaccinated due to extreme allergic reactions and to those that produce the fewest antibodies in response to coronavirus vaccines. However antibodies are just one part of the immune system, and the Facilities for Illness Management and Prevention nonetheless recommends towards utilizing exams that decide antibody ranges to evaluate somebody’s immunity.

Advertisement

“The most important drawback is that there’s completely no steering or prioritization or any rollout in place in any respect, and it’s been a large number,” mentioned Dr. Dorry Segev, a transplant surgeon at N.Y.U. Langone Well being who has been finding out coronavirus vaccines in transplant sufferers. “With out formal pointers, you actually can’t do something.”

The Biden administration is making an attempt to handle the confusion. Prime federal well being officers have been working to lift consciousness amongst state well being officers, suppliers and sufferers. They convened a name this previous week with advocates for the disabled to debate the revised dosing steering; in addition they urged affected person teams to companion with the administration on outreach and schooling efforts.

“I really feel actually strongly that this remedy has nice potential to assist the immune suppressed who don’t all the time reply to vaccinations,” mentioned Dr. Rachel Levine, the assistant secretary for well being within the Division of Well being and Human Companies, who spoke on the decision. However Dr. Levine mentioned she didn’t anticipate that the C.D.C.’s steering on antibody exams would change.

Sufferers who can’t be vaccinated are apparent candidates for Evusheld. However among the many vaccinated, Dr. Segev and different consultants say, the calculations turn into far murkier — and might contain assessments of different underlying circumstances or threat elements.

For sufferers who handle to get Evusheld, consultants say it’s nonetheless unclear precisely how a lot safety the remedy provides. It’s tough to gauge the affect of the drug in defending immunocompromised sufferers, as a result of many recruited for research have been avoiding dangerous behaviors and it will have been unethical to ask them to not. Researchers could not know the precise effectiveness of the drug for a lot of months.

Advertisement

Evusheld was discovered to supply safety akin to vaccines in a medical trial, however the variety of members who have been immunocompromised was by no means disclosed. Including to the uncertainty, AstraZeneca studied the drug earlier than Omicron surfaced. Analysis over the previous few months exhibits that Evusheld protects towards the variant, however it’s unclear to what diploma.

The shortage of strong data has annoyed Ms. Cooley, the liver transplant recipient in Mississippi. She continues to be taking the identical precautions as she did earlier than receiving Evusheld, reminiscent of getting groceries delivered, staying at house and seeing just a few trusted relations with masks on. That’s as a result of she cares for her aged mom and has seen numerous different aged folks, together with her grandmother, die from Covid-19 in her neighborhood, the place many individuals have chosen to not get vaccinated.

Some who can’t discover a dose of Evusheld have turned to on-line communities as an alternative of well being care organizations. They’re in search of assist from different immunocompromised folks, reminiscent of Dr. Vivian G. Cheung, 54, a doctor in Bethesda, Md., who has a genetic situation that impacts her immune system.

Dr. Cheung obtained a dose in January after calling numerous medical establishments for 2 weeks, and he or she has been serving to others navigate the method since then. She receives as much as 10 requests for assist daily, however she estimates that solely 1 / 4 of those that have reached out have succeeded in getting Evusheld.

Ms. Taylor, the girl in Cincinnati, has frequent variable immunodeficiency. However proper now, one hospital close to her is limiting its provide of Evusheld to its transplant sufferers, whereas one other just isn’t but accepting sufferers from outdoors its system. She is unable to look elsewhere; she mentioned she was uncomfortable driving lengthy distances due to her underlying well being circumstances.

Advertisement

Ms. Taylor mentioned that she didn’t wish to take a dose away from somebody who may want it extra, however that she would really feel much less “panic-stricken” if she might get Evusheld. She may be capable to begin seeing her youngsters indoors once more and inch again to the life she had earlier than Covid.

For now, she is in a holding sample of isolating, masking and hoping a dose will turn into accessible quickly.

Rebecca Robbins contributed reporting.

Continue Reading
Advertisement
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Science

Amid state inaction, California chef sues to block sales of foam food containers

Published

on

Amid state inaction, California chef sues to block sales of foam food containers

Fed up with the state’s refusal to enforce a law banning the sale of polystyrene foam cups, plates and bowls, a San Diego County resident has taken matters into his own hands.

Jeffrey Heavey, a chef and owner of Convivial Catering, a San Diego-area catering service, is suing WinCup, an Atlanta-based foam foodware product manufacturing company, claiming that it continues to sell, distribute and market foam products in California despite a state law that was supposed to ban such sales starting Jan. 1. He is suing on behalf of himself, not his business.

The suit, filed in the San Diego County Superior Court in March, seeks class action status on behalf of all Californians.

Heavey’s attorney, William Sullivan of the Sullivan & Yaeckel Law Group, said his client is seeking an injunction to stop WinCup from selling these banned products in California and to remove the products’ “chasing arrows” recycling label, which Heavey and his attorney describe as false and deceptive advertising.

They are also seeking damages for every California-based customer who paid the company for these products in the last three years, and $5,000 to every senior citizen or “disabled” person who may have purchased the products during this time period.

Advertisement

WinCup didn’t respond to requests for comments, but in a court filing described the allegations as vague, unspecific and without merit, according to the company’s attorney, Nathan Dooley.

Jeffrey Heavey is suing foodware maker WinCup, claiming that it continues to sell, distribute and market foam products in California despite a state law that was supposed to ban such sales starting Jan. 1.

(Luke Johnson / Los Angeles Times)

At issue is a California ban on the environmentally destructive plastic material, which went into effect on Jan. 1, as well as the definition of “recyclable” and the use of such a label on products sold in the state.

Advertisement

Senate Bill 54, signed into law by Gov. Gavin Newsom in 2021, targeted single-use plastic in the state’s waste stream.

The law included a provision that banned the sale and distribution of expanded polystyrene food service ware — such as foam cups, plates and takeout containers — on Jan. 1, unless producers could show they had achieved a 25% recycling rate.

“I’m glad a person in my district has taken this up and is holding these companies accountable,” said Catherine Blakespear (D-Encinitas). “But CalRecycle is the enforcement authority for this legislation, and they should be the ones doing this.”

The intent of the law was to put the financial onus of responsible waste management onto the producers of these products, and away from California’s taxpayers and cities that would otherwise have to dispose of these products or deal with their waste on beaches, in rivers and on roadways.

Expanded polystyrene is a particularly pernicious form of plastic pollution that does not biodegrade, has a tendency to break down into microplastics, leaches toxic chemicals and persists in the environment.

Advertisement

There are no expanded polystyrene recycling plants in California, and recycling rates nationally for the material hover around 1%.

a Mallard duck swim in a Styrofoam polluted beach

A Mallard duck swims in water with Styrofoam polluting the beach on Lake Washington, Kirkland, Wash.

(Wolfgang Kaehler / LightRocket via Getty Images)

However, despite CalRecycle’s delayed announcement of the ban, companies such as WinCup not only continue to sell these banned products in California, but Heavey and his lawyers allege the products are deceptively labeled as “recyclable.”

In his suit, Heavey includes a March 15 receipt from a Smart & Final store in the San Diego County town of National City, indicating a purchase of “WinCup 16 oz. Foam” cups.

Advertisement

Similar polystyrene foam products could be seen on the shelves this week at a Redwood City Smart & Final, including a 1,000-count box of 12-ounce WinCup foam cups selling for $36.99. Across the aisle, the shelves were packed with bags of Simply Value and First Street (both Smart & Final brands) foam plates and bowls.

There were “chasing arrow” recycling labels on the boxes containing cup lids. The symbol included a No. 6 in the center, indicating the material is polystyrene. There were none on the cardboard boxes containing cups, and it couldn’t be determined if the individual foam products were tagged with recycling labels. They were either obstructed from view inside cardboard boxes or stacked in bags which obscured observation.

Smart & Final, which is owned by Chedraui USA, a subsidiary of Mexico City-based Grupo Comercial Chedraui, didn’t respond to requests for comment.

Heavey’s suit alleges the plastic product manufacturer is “greenwashing” its products by labeling them as recyclable and in so doing, trying to skirt the law.

According to the suit, recycling claims are widely disseminated on products and via other written publications.

Advertisement

The company’s website includes an “Environmental” tab, which includes a page entitled: “Foam versus Paper Disposable Cups: A closer look.”

The page includes a one-sentence argument highlighting the environmental superiority of foam over paper, noting that “foam products have a reputation for environmental harm, but if we examine the scientific research, in many ways Expanded Polystyrene (EPS) foam is greener than paper.”

Heavey’s suit claims that he believed he was purchasing recyclable materials based on the products’ labeling, and he would not have bought the items had they not been advertised as such.

WinCup, which is owned by Atar Capital, a Los Angeles-based global private investment firm sought to have the case moved to the U.S. District Court in San Diego, but a judge there remanded the case back to the San Diego Superior Court or jurisdiction grounds.

Susan Keefe, the Southern California Director of Beyond Plastics, an anti-plastic environmental group based in Bennington, Vt., said that as of June, the agency had not yet enforced the ban, despite news stories and evidence that the product was still being sold in the state.

Advertisement

“It’s really frustrating. CalRecycle’s disregard for enforcement just permits a lack of respect for our laws. It results in these violators who think they can freely pollute in our state with no trepidation that California will exercise its right to penalize them,” she said.

Melanie Turner, a spokesoman for CalRecycle, said in a statement that expanded polystyrene producers “should no longer be selling or distributing expanded polystyrene food service ware to California businesses.”

“CalRecycle has been identifying and notifying businesses that may be impacted by SB 54, including expanded polystyrene requirements, and communicating their responsibilities with mailed notices, emailed announcements, public meetings, and workshops,” she said.

The waste agency “is prioritizing compliance assistance for producers regulated by this law, prior to potential enforcement action,” she said.

Keefe filed a public records request with the agency regarding communications with companies selling the banned material and said she found the agency had not made any attempts to warn or stop the violators from selling banned products.

Advertisement

Blakespear said it’s concerning the law has been in effect for more than six months and CalRecycle has yet to clamp down on violators. Enforcement is critical, she said, for setting the tone as SB 54 is implemented.

According to Senate Bill 54, companies that produce banned products that are then sold in California can be fined up to $50,000 per day, per violation.

According to a report issued by the waste agency last week, approximately 47,000 tons of expanded polystyrene foam was disposed in California landfills last year.

Advertisement
Continue Reading

Science

How a Supreme Court win for public health bolstered RFK Jr. and threatens no-cost vaccines

Published

on

How a Supreme Court win for public health bolstered RFK Jr. and threatens no-cost vaccines

Public health advocates won a big case in the Supreme Court on the last day of this year’s term, but the victory came with an asterisk.

The decision ended one threat to the no-cost preventive services — from cancer and diabetes screenings to statin drugs and vaccines — used by more than 150 million Americans who have health insurance.

But it did so by empowering the nation’s foremost vaccine skeptic: Health and Human Services Secretary Robert F. Kennedy Jr.

Losing would have been “a terrible result,” said Washington attorney Andrew Pincus. Insurers would have been free to quit paying for the drugs, screenings and other services that were proven effective in saving lives and money.

But winning means that “the secretary has the power to set aside” the recommendations of medical experts and remove approved drugs, he said. “His actions will be subject to review in court,” he added.

Advertisement

The new legal fight has already begun.

Last month, Kennedy cited a “crisis of public trust” when he removed all 17 members of a separate vaccine advisory committee. His replacements included some vaccine skeptics.

The vaccines that are recommended by this committee are included as preventive services that insurers must provide.

On Monday, the American Academy of Pediatrics and other medical groups sued Kennedy for having removed the COVID-19 vaccine as a recommended immunization for pregnant women and healthy children. The suit called this an “arbitrary” and “baseless” decision that violates the Administrative Procedure Act.

“We’re taking legal action because we believe children deserve better,” said Dr. Susan J. Kressly, the academy’s president. “This wasn’t just sidelining science. It’s an attack on the very foundation of how we protect families and children’s health.”

Advertisement

On Wednesday, Kennedy postponed a scheduled meeting of the U.S. Preventive Services Task Force that was at the center of the court case.

“Obviously, many screenings that relate to chronic diseases could face changes,” said Richard Hughes IV, a Washington lawyer and law professor. “A major area of concern is coverage of PrEP for HIV,” a preventive drug that was challenged in the Texas lawsuit that came to the Supreme Court.

By one measure, the Supreme Court’s 6-3 decision was a rare win for liberals. The justices overturned a ruling by Texas judges that would have struck down the popular benefit that came with Obamacare. The 2012 law required insurers to provide at no cost the preventive services that were approved as highly effective.

But conservative critics had spotted what they saw was a flaw in the Affordable Care Act. They noted the task force of unpaid medical experts who recommend the best and most cost-effective preventive care was described in the law as “independent.”

That word was enough to drive the five-year legal battle.

Advertisement

Steven Hotze, a Texas employer, had sued in 2020 and said he objected on religious grounds to providing HIV prevention drugs, even if none of his employees were using those drugs.

The suit went before U.S. District Judge Reed O’Connor in Fort Worth, who in 2018 had struck down Obamacare as unconstitutional. In 2022, he ruled for the Texas employer and struck down the required preventive services on the grounds that members of the U.S. Preventive Services Task Force made legally binding decisions even though they had not been appointed by the president and confirmed by the Senate.

The 5th Circuit Court put his decision on hold but upheld his ruling that the work of the preventive services task force was unconstitutional because its members were “free from any supervision” by the president.

Last year, the Biden administration asked the Supreme Court to hear the case of Xavier Becerra vs. Braidwood Management. The appeal said the Texas ruling “jeopardizes health protections that have been in place for 14 years and millions of Americans currently enjoy.”

The court agreed to hear the case, and by the time of the oral argument in April, the Trump administration had a new secretary of HHS. The case was now Robert F. Kennedy Jr. vs. Braidwood Management.

Advertisement

The court’s six conservatives believe the Constitution gives the president full executive power to control the government and to put his officials in charge. But they split on what that meant in this case.

The Constitution says the president can appoint ambassadors, judges and “all other Officers of the United States” with Senate approval. In addition, “Congress may by law vest the appointment of such inferior officers” in the hands of the president or “the heads of departments.”

Option two made more sense, said Justice Brett M. Kavanaugh. He spoke for the court, including Chief Justice John G. Roberts and Justice Amy Coney Barrett, and the court’s three liberal justices.

“The Executive Branch under both President Trump and President Biden has argued that the Preventive Services Task Force members are inferior officers and therefore may be appointed by the Secretary of HHS. We agree,” he wrote.

This “preserves the chain of political accountability. … The Task Force members are removable at will by the Secretary of HHS, and their recommendations are reviewable by the Secretary before they take effect.”

Advertisement

The ruling was a clear win for Kennedy and the Trump administration. It made clear the medical experts are not “independent” and can be readily replaced by RFK Jr.

It did not win over the three justices on the right. Justice Clarence Thomas wrote a 37-page dissent.

“Under our Constitution, appointment by the President with Senate confirmation is the rule. Appointment by a department head is an exception that Congress must consciously choose to adopt,” he said, joined by Justices Samuel A. Alito and Neil M. Gorsuch.

Advertisement
Continue Reading

Science

Life expectancy in California still hasn't rebounded since the pandemic

Published

on

Life expectancy in California still hasn't rebounded since the pandemic

During the height of the COVID-19 pandemic, the virus caused life expectancy in California to drop significantly.

It’s now been over two years since officials declared the pandemic-related public health emergency to be over. And yet, life expectancy for Californians has not fully recovered.

Today, however, the virus has been replaced by drug overdoses and cardiovascular disease as the main causes driving down average lifespans.

A new study published in the medical journal JAMA by researchers from UCLA, Northwestern, Princeton and Virginia Commonwealth University finds that the average life expectancy for Californians in 2024 was nearly a year less than in 2019. The shortfall of 0.86 year signals that only about two-thirds of the state’s pandemic-era losses of 2.92 years have been reversed.

Using mortality data from the California Comprehensive Death Files and population estimates from the American Community Survey, the researchers calculated annual life expectancy from 2019 to 2024, breaking the figures down by race, ethnicity, income and cause of death.

Advertisement

Although the COVID-19 virus was the primary factor in life expectancy declines during the pandemic’s peak, accounting for 61.6% of the life expectancy gap, its impact has significantly lessened. In 2024, COVID-19 accounted for only 12.8% of the life expectancy gap compared with 2019, while drug overdoses and cardiovascular disease contributed more — 19.8% and 16.3%, respectively.

For Black and Hispanic Californians, recovery has been even slower. Life expectancy for Black residents in 2024 remained 1.48 years below 2019 levels, while for Hispanic residents it was 1.44 years lower. In contrast, the gap for white residents was 0.63 year, and for Asian residents, who have the highest life expectancy in the state at 85.51 years, it was 1.06 years. Overall, the life expectancy for Black Californians in 2024 was under 73.5 years, more than a dozen years lower than that of Asian Californians.

Janet Currie, a co-author of the study and professor at Princeton University, noted that these disparities are especially striking. “You saw the very big hit that Hispanic people and Black people took during the pandemic,” she said, “but you also see that Black people in particular are still not caught up.” She added that although Hispanic populations saw a faster rebound, they too remain behind.

Income-based disparities in life expectancy persist in stark form. Californians living in the lowest-income census tracts (the bottom quartile) experienced a 0.99-year gap in 2024 compared with 2019, while those in the highest-income quartile had a slightly smaller 0.85-year gap. However, the overall life expectancy difference between these groups, 5.77 years, was nearly identical to the prepandemic gap of 5.63 years, suggesting that income-based health disparities persist even as pandemic impacts recede.

The study highlights drug overdoses as a primary post-pandemic-emergency driver of reduced life expectancy. Black Californians and residents of low-income areas were especially affected. In 2023, drug overdoses contributed nearly a full year (0.99 year) to the life expectancy deficit for Black Californians and over half a year (0.52) for residents of low-income areas.

Advertisement

That said, there are signs that state and national efforts to address the overdose crisis may be yielding early results. The number for Black Californians declined to 0.55 year in 2024 while it declined to 0.26 year for residents in low-income areas; in the same time frame, the statewide number dropped from 0.4 year to 0.17 year.

Currie attributed the initial surge in overdose deaths in part to the pandemic itself; there were disruptions in access to treatment, and many Californians suffered greater isolation. While she welcomed the recent progress, she cautioned that the share of deaths attributable to overdoses remains high and emphasized that this was “one of the real bad consequences of the pandemic.”

Meanwhile, cardiovascular disease is now the leading contributor to life expectancy loss among high-income Californians. In 2024, it accounted for 0.22 year of the gap for the wealthiest quartile, more than COVID-19 did at 0.10 year. The authors note this is consistent with statewide rising rates of obesity, which may be playing a role.

Dr. Tyler Evans, chief medical officer and chief executive of Wellness Equity Alliance as well as the author of the book “Pandemics, Poverty, and Politics: Decoding the Social and Political Drivers of Pandemics from Plague to COVID-19,” emphasized how the pandemic exacerbated long-standing health inequities. “These chronic health inequities were further amplified as the result of the pandemic,” he said. While investments in social determinants of health initially helped mitigate some of the worst outcomes, he added, “the funding dried up,” making recovery harder for communities already at greater risk of poor outcomes.

Evans also pointed to a broader pattern of overlapping health crises that he described as a “syndemic,” a convergence of epidemics such as addiction, chronic disease and poor access to care that interact to worsen outcomes for historically marginalized populations. “Until we invest in that sort of foundation long term, the numbers will continue to decline,” he said. “California should be a leader in health improvement outcomes in the country, not a state that continues to have our survival decline.”

Although the findings are limited to California and based on preliminary 2024 data, the study provides an early glimpse into post-pandemic mortality trends ahead of the Centers for Disease Control and Prevention’s national life expectancy dataset, expected to be published later this year. California, home to one-eighth of the U.S. population, provides valuable insight into how racial, ethnic and socioeconomic disparities continue to shape public health.

Advertisement

Ultimately, the study highlights how although the most visible impacts of COVID-19 may have faded, their ripple effects, compounded by ongoing structural inequities, continue to shape life and death in California. The pandemic may have accelerated long-standing public health challenges, and the recovery, the study makes clear, has been uneven and incomplete.

Currie warned that further cuts to Medicaid and public hospitals could make these gaps even worse. “We know what to do. We just don’t do it,” she said.

Continue Reading

Trending