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(Opinion) Biden administration proposal would harm New Hampshire researchers and patients – NH Business Review

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(Opinion) Biden administration proposal would harm New Hampshire researchers and patients – NH Business Review


New plan could prevent university medical discoveries from making it out of the lab

The National Institutes of Health awarded over $157 million in research grants to Dartmouth, the University of New Hampshire, and other institutions across the state last year. This funding, and similar grants from other federal agencies, help researchers make groundbreaking discoveries across a host of sectors, from life sciences and agriculture to computing and energy.

Yet a new proposal from the Biden administration could prevent the most exciting university discoveries from making it out of the lab.

The plan would give federal officials unprecedented power to interfere in the contracts signed between academic research institutions and private companies. That’d discourage companies from licensing the discoveries made by these institutions, and thereby prevent firms from turning universities’ good ideas into tangible products.

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The proposal dramatically reinterprets the government’s “march-in” rights under the Bayh-Dole Act of 1980.

Most Americans have likely never heard of that bipartisan law, which has fueled our country’s medical and technological innovation for four decades. The Bayh-Dole Act allowed universities, other research institutions and small businesses to retain the patent rights on discoveries they made with the help of federal grants.

These institutions could then license those patents to private companies willing to take on the risk of developing real-life products.

Before Congress passed that law, the government took the patent rights on discoveries stemming from federally funded research. And because the government rarely licensed those patents, few companies worked to commercialize theoretical breakthroughs into products. Without secure patent rights, they had no incentive to, as they had no way to stop competitors from piggybacking on their work and undercutting them in the marketplace.

Put another way, taxpayers’ research dollars were advancing our collective understanding of science, but we had few tangible advances to show for it.

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Bayh-Dole changed that by incentivizing universities to partner with companies to bring those discoveries to market. Since 1980, the patent licensing — and subsequent research, development and manufacturing — enabled by the Bayh-Dole Act has directly contributed $1 trillion to the U.S. gross domestic product and supported 6.5 million jobs. The law has been especially impactful in life sciences, leading to the development of more than 200 vaccines and life-saving drugs.

One notable example of these drugs is infliximab, which originated from research at New York University School of Medicine and was later licensed and commercialized by Janssen Biotech, now part of Johnson & Johnson, in 1998. The medicine is commonly used to treat certain forms of arthritis, which affects roughly 280,000 New Hampshire residents and one in four U.S. adults nationwide.

If the Biden administration’s proposal were in place in the 1990s, this medicine might not have made it to patients, as companies would have had very little reason to risk capital on federally funded research. Why spend billions of dollars, and more than a decade, bringing a new technology to market if the government can simply snatch the patent rights as soon as it reaches the shelves?

That is, effectively, what the new plan envisions. Drugs and other technologies would once again never make it out of university laboratories, and American patients would be at the brunt of the medical drought.

New treatments for arthritis and other diseases are just around the corner. But no matter how promising the science, those prospective treatments will never reach patients if the administration gets its way.

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Julia Moore is executive director of Rhode Island and Northern New England for the Arthritis Foundation. 





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New Hampshire

New Hampshire towns opt out of hosting casinos – Valley News

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New Hampshire towns opt out of hosting casinos – Valley News


Eight New Hampshire municipalities have moved to block the opening of casinos within their borders, taking advantage of a new state law that gives communities the power to opt out of hosting gambling establishments.

Amy Manzelli, president of the board of Granite Staters for Responsible Gaming, said the law, which took effect last year, has been widely welcomed by residents who value the ability to have a direct say in which establishments shape the character of their town or city.

“In New Hampshire, there’s a pretty deep and passionate vein of local control,” she said.

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Henniker, N.H., Candia, N.H., Bedford, N.H., Barrington, N.H., Hancock, N.H., New London and Littleton, N.H., voted to bar casinos within their municipal boundaries. The city of Portsmouth, N.H., moved to block gambling establishments within its city limits within three months of House Bill 737 being signed into law by the governor.

Conway, N.H., is expected to hold a similar vote on April 14.

This is separate from the option towns and cities have to opt out of Keno, a state-run lottery game.

State Rep. Bill Boyd, R-Merrimack, who sponsored both the casino opt-out bill and the legislation allowing social districts in municipalities last year, said the two laws share the same philosophy: giving towns more control over what is allowed within their boundaries.

“I’m not surprised, but I’m very happy with the immediate engagement because it tells me that people are paying attention to local control and how they want their communities to look,” Boyd said of the number of towns that have already acted under the new law.

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When gaming establishments were first legalized in New Hampshire, they were envisioned as small, locally-owned operations. The industry has since grown dramatically, with gaming halls now functioning as large-scale entertainment venues complete with restaurants and live shows. New Hampshire’s gaming industry is on track to become a $1.1 billion market within three years, according to experts.

That rapid growth has left many communities uneasy about the demands large gambling venues could place on local infrastructure, including emergency services and traffic management, Manzelli said.

“New Hampshire doesn’t really have a great mechanism for making sure municipalities have a way of dealing with those impacts,” she said. “As the gaming industry evolved, the laws were written for your classic ‘Mom and Pop’ type bingo night, very small-scale establishments.”

The law includes a grandfather clause protecting casinos that are already operating or were in the pipeline at the time a community votes to opt out.

In Littleton, plans for a casino proposed by an out-of-state operator have been in development for at least three years. In February, a casino developer, GSG Littleton Propco LLC, purchased a property in town for a gaming establishment, according to state and town records.

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Since those plans predate the town’s opt-out vote, they would not be affected by it, Boyd said.

Under the law as written, it only prevents new casinos from being sited in communities that have passed such a vote.

“Even if towns like Littleton don’t want you, you’ve got 260-some odd cities and towns that exist in the state of New Hampshire. “I would think they (casinos) could find a community that would say, ‘we really want you to come to our community,’ and they will welcome them with open arms and work with their local system to make the facility happen,” Boyd said.



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New Hampshire

General John Stark Day celebrated in NH

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General John Stark Day celebrated in NH


General John Stark Day celebrated in New Hampshire

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TRAFFIC AND INTERDICT ILLEGAL ACTIVITY MORE EFFICIENTLY. TODAY, THE GRANITE STATE CELEBRATES THE LEGACY OF GENERAL JOHN STARK. THE SECOND MONDAY OF APRIL IS OBSERVED AS GENERAL JOHN STARK DAY. HE WAS A HERO OF THE AMERICAN REVOLUTION AND IS CREDITED WITH WRITING THE WORDS THAT BECAME NEW HAMPSHIRE’S MOTTO. HE WROTE, QUOTE, LIVE FREE OR DIE. DEATH IS NOT THE WORST OF EVILS, WHICH WAS LATER SHORTENED TO LIVE FREE OR DIE. A LOT OF PEOPLE IN OUR COUNTRY, EVERY GENERATION, MEN AND WOMEN WHO HAVE SERVED, ARE WHY WE ARE FREE. IT’S NOT JUST GENERAL STARK. HE SHOWED US THE WAY AND GENERAL WASHINGTON, BUT EVERY GENERATION OF MEN AND WOMEN WHO HAVE SERVED OUR COUNTRY HAVE ENSURED THAT FREEDOM. STARK IS MOST WELL KNOWN FOR SERVICE AT THE BATTLE OF BENNINGT

The Granite State honored the legacy of Gen. John Stark on Monday. Gen. John Stark Day is observed on the second Monday in April. Stark was a hero of the American Revolution and is credited with writing the words that became New Hampshire’s state motto. He wrote “Live Free or Die: Death is not the worst of evils,” later shortened to “Live Free or Die.”>> Download the free WMUR app to get updates on the go

The Granite State honored the legacy of Gen. John Stark on Monday.

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Gen. John Stark Day is observed on the second Monday in April.

Stark was a hero of the American Revolution and is credited with writing the words that became New Hampshire’s state motto. He wrote “Live Free or Die: Death is not the worst of evils,” later shortened to “Live Free or Die.”

>> Download the free WMUR app to get updates on the go

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“A lot of people in our country, every generation, men and women who have served, are why we are free,” said Gov. Kelly Ayotte. “It’s not just General John Stark. He showed us the way, and General Washington, but every generation of men and women who have served our country have ensured that freedom.”

Stark is known for his service at the Battle of Bennington in Vermont.

He retired in 1810 and died in Manchester in 1822.

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New Hampshire

Proposed bills to address New Hampshire’s insect crisis – Valley News

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Proposed bills to address New Hampshire’s insect crisis – Valley News


The New Hampshire Senate Committee on Energy and Natural Resources heard two ideas to address shrinking insect populations in New Hampshire during a Tuesday hearing.

One measure, House Bill 1431, would direct the state Pesticide Control Board to reclassify a group of pesticides that is particularly harmful to pollinators and wildlife as restricted use, meaning their use would be limited to professional pesticide applicators. The group of pesticides, called neonicotinoids, has been linked to ecosystem-wide effects from insect and bird population declines to cyanobacteria blooms.

Another bill, House Bill 1086, would establish a committee to study the feasibility and possible outcomes of a ban on seeds treated with neonicotinoid pesticides. Seed treatments are common in grain crops, including corn.

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Both bills were sponsored by Rep. John MacDonald, R-Wolfeboro.

“We have to do something,” MacDonald said Tuesday. “I’m not trying to take away any powers of the Pesticide Control Board, but nobody’s doing anything. And I don’t know, I can’t figure out why.”

The windshield effect and beyond

Rosemary Malfi, director of conservation policy for the insect conservation nonprofit Xerces Society, said the decline of insects in New Hampshire is evident in the “windshield effect.”

“Do you remember, anyone who drove a car in the ’90s or early 2000s, you actually got bugs on your windshield? I think everyone here probably knows that that doesn’t happen so much anymore. Neonicotinoid insecticides, or ‘neonics,’ are a major contributor to these declines,” she said.

Forty percent of the bumblebee species historically found in New Hampshire are locally extinct or in severe decline, while about 70% of butterfly species are losing numbers, too, Malfi said. Other classes of insects, including aquatic insects, are affected as well.

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This ripples out to affect animals higher up the food chain, including fish and birds. Beneath insects on the ecosystem ladder, meanwhile, are the microorganisms that contribute to harmful cyanobacteria blooms; this means that insect decline can allow cyanobacteria to proliferate, potentially worsening those costly problems, said Rep. Peter Bixby, D-Dover.

Learning from neighbors

As proposed, HB 1086 calls for a committee of three representatives and one senator to assess data from Quebec and New York, where bans on neonicotinoid treated seeds are in place already. They could also assess information from other areas with bans, MacDonald said.

The committee would assess whether bans in other regions have affected crop yields. Some speakers on Tuesday said studies show neonicotinoid seeds to be ineffective at increasing yields.

“We’re concerned that our agricultural community is being asked to pay for a product on seeds that isn’t necessarily helping productivity, but is having serious consequences, both to soil ecology and to water ecology,” said Carol Foss, senior adviser for science and policy with NH Audubon.

Nisa Marks, a wildlife biologist and organic farmer from Henniker, N.H., said neonicotinoids were not necessary for successful crops. But some farmers who attended said restrictions could harm them. Sarah Wrocklage, of Tecce Farm in Durham, N.H., said pests would cause losses on her farm if she could not treat them with chemicals.

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In her testimony, Wrocklage also touched on another area that the committee would be directed to consider: Whether it would be possible for farmers to switch to untreated seeds at all. Some of the sweetcorn that Tecce Farm plants is only available in treated form, Wrocklage said.

She and another farmer, Chuck Souther of Concord’s Apple Hill Farm, called for more involvement of local farmers and New Hampshire experts, including those from the University of New Hampshire. As proposed, they said, they did not support the bill, feeling it did not adequately take into account the unique circumstances on New Hampshire farms.

“We do need to look at this, but we need to look at it under New Hampshire conditions,” Souther said.

Requiring action

Though conservationists and farmers agreed insect decline was a problem, at the Tuesday hearings, some senators and speakers questioned the necessity of the bills.

Sen. Howard Pearl, R-Loudon, who is vice chair of the Energy and Natural Resources Committee, asked if a study committee was necessary given the associated costs.

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MacDonald said it was. The committee called for in HB 1086 would be “targeted, efficient, and time-bound,” he said. It is designed to last through the summer of 2026 and deliver a report in November.

On HB 1431, speakers, including Robert Johnson of the New Hampshire Farm Bureau Association, suggested the task of restricting neonicotinoid use should be left up to the Pesticide Control Board. Johnson said he disagreed with directing the board’s actions through legislation.

But MacDonald said he had been part of conversations and a subcommittee with the Pesticide Control Board regarding neonicotinoids and had seen no action resulting from those meetings.

“This bill provides clarity on whether action is optional or whether it’s required,” he said.

Both bills have been amended from their original form. As introduced, HB 1086 proposed a ban on seed coatings rather than a study committee, while HB 1431 originally proposed more restrictions, including prohibitions on the use of chemicals on state property and on flowering plants. It also originally sought to make the violation of these rules a misdemeanor for individuals and a felony for organizations or companies. But as amended, the bill leaves more elements of the ban in the hands of the Pesticide Control Board.

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Rep. Jonah Wheeler, D-Peterborough, said he had favored a stricter version of both bills in committee discussions, but believed the amended legislation would be a step forward nonetheless. The legislation “deals with a really urgent issue that our constituents are begging us to tackle,” he said.

“The more that we as a society find ourselves away from … symbiosis with the environment in which we live, the natural harmony that exists on this planet, then the more we will find ourselves with problems like pest infestations,” he said.



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