Connect with us

Science

The longer a species stays in the wildlife trade, the more dangerous it becomes. A new study explains why

Published

on

The longer a species stays in the wildlife trade, the more dangerous it becomes. A new study explains why

Animals traded through global wildlife markets are far more likely to carry diseases that can infect humans, and the risk grows the longer those species remain in circulation, according to a new study.

The analysis, published Thursday in Science, examined decades of global wildlife trade data and found that 41% of traded mammal species share at least one pathogen with humans, compared with just 6.4% of species not involved in trade.

The researchers also found that the number of pathogens shared between animals and humans increases over time. On average, a species acquires one additional human-infecting pathogen for every decade it is present in the global wildlife trade.

The findings suggest that wildlife trade does not simply expose humans to existing disease risks, but may actively amplify them over time.

“Our study is the strongest evidence to date that reducing wildlife trade will reduce pandemic risk,” said Colin Carlson, an epidemiologist at the Yale School of Public Health and a co-author of the study.

Advertisement

Scientists have already long linked wildlife trade to specific outbreaks such as HIV, Ebola and COVID-19. The new research, which draws on 40 years of global trade records and pathogen data, attempts to measure the relationship on a larger scale.

The results point to a broader pattern. Repeated and prolonged contact between humans and wild animals creates more opportunities for pathogens to move between species.

“What stands out most is how clearly the findings reinforce something many of us in disease ecology have been concerned about for years: it’s not just the presence of wildlife trade, but the intensity and duration of contact that elevates risk,” said Thomas Gillespie, a professor of environmental sciences and environmental health at Emory University, who was not involved in the study.

Wildlife trade, as defined in this study, includes a wide range of activities, from hunting and breeding to transport, storage and sale. At each stage, animals are handled, confined and often brought into close proximity with both humans and other animal species. These conditions can facilitate the spread of viruses, bacteria and parasites.

Over time, those repeated interactions create more opportunities for pathogens to circulate, adapt and potentially spill over into human populations.

Advertisement

Carlson said one of the most striking findings was how strongly time in trade predicted pathogen sharing.

“That time-in-trade effect is the smoking gun,” he said. “We wouldn’t see that unless pathogens were jumping from animals to humans.”

He added that the findings suggest wildlife trade should be considered one of the major drivers of disease emergence, alongside deforestation, agriculture and climate change.

The study also found that certain forms of trade may carry higher risks. Species sold in live-animal markets were more likely to share pathogens with humans than those sold as meat or animal products. Illegally traded species also were more likely to be the cause of disease, though researchers emphasized that risk is not limited to illicit markets.

“Focusing on illegal wildlife trade is not enough,” said Meredith Gore, a conservation criminologist at the University of Maryland and a co-author of the study. “Pathogen transmission is a consequence of general and diverse uses of wildlife by people. This includes illegal and legal trade.”

Advertisement

Most international frameworks governing wildlife trade, including the Convention on International Trade in Endangered Species of Wild Fauna and Flora, or CITES, were designed primarily to protect species from overexploitation, according to Gore.

“There are clear and currently unmet opportunities for more directly including zoonotic disease risk consideration into current regulations,” Gore said.

In particular, the global nature of the trade complicates efforts to manage risk.

“Animals and pathogens do not care about political borders,” said Jérôme Gippet, a biologist at the University of Fribourg and the University of Lausanne in Switzerland and the study’s lead author. “Without globally coordinated efforts, I do not see how we can limit these risks efficiently.”

The researchers say their findings underscore the need for a more coordinated approach that bridges conservation, public health and trade policy and treats wildlife trade as a central driver of global health risk. The study’s findings also highlight gaps in disease surveillance systems, which often fail to detect pathogens circulating in wildlife before they reach humans.

Advertisement

“Risk is accumulating in a way that current surveillance isn’t capturing,” said Evan Eskew, a disease ecologist at the University of Idaho and a co-author of the study.

Few countries, he said, systematically track which species are being traded across their borders, and even fewer conduct routine pathogen screening in those animals. As a result, potential threats can go undetected until they spill over into human populations.

Eskew said expanding surveillance, particularly for species already known to carry zoonotic pathogens, could help identify risks earlier and prevent outbreaks from spreading.

“We need to be looking for the next pandemic virus on fur farms, in hunting communities, and even at border checkpoints where wildlife are imported,” Carlson said. “Right now, we’re flying blind, especially in places where we’ve criminalized wildlife trade and driven it underground.”

Advertisement

Science

A Landslide in Alaska Set Off a Tsunami. There May Be More to Come.

Published

on

A Landslide in Alaska Set Off a Tsunami. There May Be More to Come.

Nearly 500 feet up a near-vertical rock face, scraped clean of soil and alder trees, Bretwood Higman, a geologist, looked down across the Tracy Arm fjord in southeast Alaska at a scene of devastation.

At 5:26 a.m. on Aug. 10 last year, a mass of rock with a volume 24 times larger than that of the great pyramid of Giza crashed down the mountainside, sending a wave of water 1,578 feet up the opposite wall and setting off a tsunami that roared down the fjord. It swept over the ridge that Dr. Higman was now standing on. The whole thing took about a minute.

Dr. Higman was part of an international team investigating the aftermath of the geologic event, the second largest landslide-generated tsunami on record. Using computer models, the researchers were able to recreate the landslide and tsunami, as well as a standing wave called a seiche that sloshed back and forth for 36 hours after the landslide.

Among other things, the new study, published on Wednesday in the journal Science, revealed how tricky it is to predict such catastrophic landslides before they take place.

The Tracy Arm landslide was preceded by an unusually rapid retreat of the South Sawyer Glacier, leaving the rock slope that ultimately collapsed bare and unsupported. That same rearrangement of land elements is increasingly occurring throughout Alaskan fjords and around the world. As glaciers retreat and thawing permafrost lubricates slopes, these giant landslides may become more frequent.

Advertisement

Scientists have been sounding the alarm about the emerging hazards of climate-linked giant landslides in Alaska for years. In 2020, Dr. Higman discovered a slow-moving landslide in the Barry Arm fjord that he worried could collapse catastrophically and inundate the nearby town of Whittier with a tsunami.

“We’re rapidly approaching a totally new landscape that has way fewer glaciers in the Alps and really everywhere, and a lot of new lakes,” said Mylène Jacquemart, a glaciologist at ETH Zurich who was not involved in the study. She studied the Blatten landslide that buried a Swiss village in rock, ice and water last year.

Jackie Caplan-Auerbach, a seismologist at Western Washington University and an author on the new study, was among the first to hear about the tsunami: Her neighbors, whose boat was anchored at sea some 50 miles from the landslide, texted her about a strange surge of water that had hit their vessel. Other firsthand accounts trickled in from Harbor Island, where camping kayakers said their gear had been carried away by the wave, and from a 150-passenger cruise ship, the National Geographic Venture, that was sitting just outside the fjord.

The stakes are high for detecting these events ahead of time. Although no vessels were in Tracy Arm fjord proper when the landslide hit, that mostly came down to luck: It was early morning and not many boats were about.

But three large cruise ships carrying thousands of passengers and numerous small tour boats visit the fjord daily, ferrying tourists right up to the glacier’s calving face. Had the Venture been up the fjord, instead of at its mouth, the wave would have been “unsurvivable,” Dr. Higman said.

Advertisement

Increased cruise-ship tourism to glacial fjords, and more oil and gas exploration in the Arctic, mean “we, as a global society, are putting more infrastructure and people in harm’s way,” said Dan Shugar, a University of Calgary geomorphologist and the study’s lead author.

Scientists at the U.S. Geological Survey and its state counterpart in Alaska look for slopes along the vast coastline that are moving toward collapse, using satellite radar and optical imagery. Because resources are limited, only Barry Arm is monitored in real time, with on-the-ground scientific instruments. Detailed assessments of a handful more moving slopes are underway in Glacier Bay National Park, which is also frequented by cruise ships.

Dr. Shugar said Tracy Arm “throws a wrench in” the strategy of looking for slope deformation “because it happened, as far as we can tell, without much warning.” Scientists were unable to detect any deformation in the slope before the collapse.

But when Dr. Caplan-Auerbach dug deeper into the seismic data from the landslide, she noticed patterns of land movement similar to those that she had studied for decades, which sometimes preceded landslides on volcanic slopes.

These tremors were “probably tiny bits of slip on the base of the landslide, and it can do that only so much before it’s got to break apart and fall,” she said. Tiny coalescing fractures within the mountain eventually reach a crescendo, a threshold at which point the rock can no longer hold itself together, and the slope gives way.

Advertisement

It is not yet clear how many landslides display these seismic signals as precursors, but since there were no other cautionary signs, they provide a hope of early warning. If the signals are subtle — the slopes “whispering to us, not yelling,” as Dr. Caplan-Auerbach put it — it is possible the seismometer network in Alaska is spread too thin to typically pick them up.

“The bar is, can we do better than missing most of these,” said Noah Finnegan, a geomorphologist at the University of California, Santa Cruz, who was not involved in the study. “So getting a handle on why these precursors happen and what their relationship is to catastrophic collapse is an area many people are interested in.”

Last month, three cruise lines notified customers that their ships would not visit Tracy Arm this year, opting instead for nearby Endicott Arm and Dawes Glacier. “That’s probably a wise move, but there’s no reason why Endicott is any safer than Tracy,” Dr. Shugar said.

Stephen Hicks, a seismologist at the University College London and an author on the study, said the planet is entering a new era when warming has penetrated geology.

“When we think about climate change, we think about impacts in the atmosphere and rising sea levels,” he said. “We sort of look up and across, but we don’t often look down,” he added, but now “the ground has moved beneath all our feet.”

Advertisement

Many open questions remain. But among the biggest, Dr. Higman said, is whether we can expect a significant increase in such events as a result of climate change, as some studies suggest.

“If it’s a dice you roll every 50 years, well, maybe that’s all right,” he said. “But if it’s one you’re rolling once or twice a year, then this is really, really urgent.”

Continue Reading

Science

Her Self-Experiment with Drug Detox Almost Broke Her

Published

on

Her Self-Experiment with Drug Detox Almost Broke Her

A 27-year-old woman began an experiment on herself early one morning in December 2024. Her laboratory was her childhood bedroom, tucked into a second-floor corner of a pale yellow house in the Boston suburbs. On a bookshelf behind her sat a small stuffed sloth and some favorite books, including “Siddhartha” by Hermann Hesse. Her parents were asleep in the room next door.

Her name is Rebecca, but she goes by Becks. Sitting at her desk in a gray T-shirt, she opened a small plastic bag filled with white powder. The bag was stamped “SR-17018,” and “NOT FOR HUMAN CONSUMPTION.”

She extracted some powder with a red microscooper, poured it onto a digital scale and carefully weighed out 25 milligrams. She gathered this into a blue and white pill capsule and sealed it, and then swallowed the capsule with water. It was 4:27 a.m.

“It’s my turn to be a guinea pig,” Becks wrote in the online diary she was keeping of her experience. In sharing her story with The New York Times, she asked that her last name not be used so potential employers don’t discover her drug history.

Becks had joined the vanguard of a dangerous, highly speculative do-it-yourself approach to getting sober. For a decade, on and off, she had been addicted to various drugs, most recently kratom, an opiate-like substance, which cleared her head and covered up her pain but required constant dosing. She feared the call of fentanyl, which she’d tried a few times.

Advertisement

“Every morning, I woke drenched in sweat from overnight withdrawals. It was a grim existence,” she wrote of her kratom use. She tried various methods to get sober, including three short inpatient detox stays and one monthlong rehabilitation treatment. She had periods of sobriety but couldn’t sustain it.

Then she heard about SR-17018, one of many new and unpredictable synthetic drugs made largely in China and sold online even though it is not approved or shown to be safe, and can pose lethal risks.

Most of these compounds, known as novel psychoactive substances, are designed to get people high. Among those substances, SR-17018 stands virtually alone in that people are using it to try to free themselves of addiction, and some claim it helps.

Excitement about SR-17018 grew after Reddit users discovered a 2019 study suggesting it could free drug-addicted mice of their dependence.

Advertisement
Continue Reading

Science

RFK Jr. clears path for minors’ use of tanning beds, much to the dismay of dermatologists

Published

on

RFK Jr. clears path for minors’ use of tanning beds, much to the dismay of dermatologists

Days before the 2024 presidential election, future Health and Human Services Secretary Robert F. Kennedy Jr. posted a statement on X promising to end the U.S. Food and Drug Administration’s “aggressive suppression” of such alternative therapies as raw milk, ivermectin, psychedelics and, somewhat perplexingly, “sunshine.”

While the post did not explain how the FDA was limiting Americans’ access to the sun, many dermatologists were dismayed when Kennedy abruptly withdrew a proposed FDA rule that would have banned minors from using devices that mimic sunlight — indoor tanning lamps.

The rule, which was withdrawn March 16, would have also required indoor tanning facility users to sign a form acknowledging the risk of cancer, early skin aging and other health effects.

Kennedy’s action comes at a time when many adherents of his Make America Healthy Again movement have adopted regular sun exposure as a core principle of wellness, with social media influencers encouraging followers to abandon sunscreen and build up their “solar callus,” or sun tolerance, instead.

Advertisement

The trend has frustrated many dermatologists, who warn that the damage of frequent sunburns and tans accumulates over a lifetime, and those acquired early in life appear to play a disproportionate role in later risk of skin cancer. The Skin Cancer Foundation notes also that you cannot build up a tolerance to sun exposure and “there is no such thing as a ‘solar callus.’”

Dermatologists have long cautioned that indoor tanning lamps are no less dangerous, since they expose users to ultraviolet light at concentrations far above natural sunlight. Like sunlight, the lamps emit two different types of ultraviolet wavelengths: UVA, which are longer and penetrate more deeply into the skin, and UVB, which are shorter and more easily burn the outer layers.

Both light sources darken skin through the same biological process: UV rays change the structure and chemical profile of DNA in the skin, which then produces more melanin in order to prevent further damage.

A tanning bed session exposes users to UVB rays akin to those at noon at the equator — an intense experience, but at least one with a terrestrial equivalent, said Hunter Shain, an associate professor of dermatology at UC San Francisco. The UVA radiation in a tanning bed is roughly 15 times that found anywhere on the surface of the planet.

“They’re really blasting you with these super physiological doses of UV radiation that you couldn’t even find in a natural environment,” he said.

Advertisement

The World Health Organization counts UV-emitting tanning beds as a Group 1 carcinogen, alongside other known human carcinogens like tobacco cigarettes and asbestos. One study Shain co-authored found that tanning beds accelerate DNA mutations in parts of the body not typically exposed to the sun, leading to a nearly threefold increase in indoor tanners’ lifetime melanoma risk. Rates of melanoma diagnoses have increased by 46% in the last decade.

The tanning lamp rule, which was first proposed in 2015, focused on age as a specific risk factor. Tanning bed usage before the age of 35 is associated with a 75% increase in the risk of melanoma, the most serious and frequently fatal form of skin cancer.

The rule drew more than 9,000 public comments from both physicians and cancer research organizations supporting its implementation and from tanning bed industry representatives and business owners opposed.

Kennedy, who was photographed leaving a Washington tanning salon last year, was ultimately unconvinced of the need to ban minors from such establishments.

“In light of the scientific and technical concerns raised in the comments on the Proposed Rule, concerns regarding possible unintended consequences of certain proposals in the Proposed Rule, and potential alternatives proposed in comments received on the Proposed Rule, FDA is withdrawing the Proposed Rule in order to reconsider the best means for addressing the issues,” Kennedy wrote in the withdrawal letter.

Advertisement

Health and Human Services did not respond to questions about what scientific concerns and unintended consequences Kennedy was referring to.

Nineteen states (including California) and the District of Columbia have already banned people under 18 from indoor tanning salons. Roughly two dozen more have some kind of regulations regarding minors and indoor tanning, such as requiring parental permission or barring only younger children.

The collapse of the proposed federal ban has left many dermatologists disappointed.

“As you can see, when it’s left to the states, the implementation and the guardrails to minimize the exposure to carcinogens are not consistent. … Why are you going to default to a system that we know isn’t working correctly?” said Dr. Clara Curiel-Lewandrowski, chair of dermatology and co-director of the Skin Cancer Institute at the University of Arizona.

Minors in sun-baked Arizona are free to patronize indoor tanning establishments as long as they have a note from their parents. Curiel-Lewandrowski has treated many former sunbed enthusiasts for advanced melanoma in their 20s and 30s, she said.

Advertisement

“There’s a lot of regret. Regret for not knowing more, for not getting more help to understand the threat,” she said. “This is an age group that has a very hard time assessing risk. At that age, they don’t view carcinogens as a real threat.”

The U.S. is a bit of an outlier in its permissive approach to youth indoor tanning. Australia and Brazil have banned cosmetic indoor tanning entirely for people of all ages. Most western European countries ban minors from indoor tanning, as do most Canadian provinces.

“After the proposal lay dormant for more than a decade, I can’t say I was surprised to hear that the FDA withdrew it,” said Dr. Deborah S. Sarnoff, president of the Skin Cancer Foundation. “On the positive side, we made the public very aware of this issue, and this fight is far from over. We won’t be satisfied until tanning beds are banned in this country.”

Advertisement
Continue Reading
Advertisement

Trending