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What to Know About the Marburg Virus Disease

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What to Know About the Marburg Virus Disease

Ghana introduced the nation’s first outbreak of Marburg virus illness after two individuals who weren’t associated died on June 27 and 28. Phrase of a brand new outbreak of a deadly illness brought on by viral infections added to the considerations of a public weary from battling the coronavirus pandemic, and not too long ago alarmed by the unfold of monkeypox and a brand new case of polio.

Medical doctors and public well being consultants within the nation instantly began looking for anybody who had been uncovered and investigating the reason for the unfold in an effort to comprise an infection. For now, well being researchers in Ghana and in different elements of the world stated that there was no indication that the virus had unfold additional.

Marburg was first detected in 1967, when outbreaks of hemorrhagic fever occurred concurrently in laboratories in Marburg and Frankfurt in Germany, and in Belgrade, in what’s now Serbia — in instances that had been linked to African inexperienced monkeys imported from Uganda. Different instances have since been present in Angola, the Democratic Republic of Congo, Kenya, South Africa and Uganda, in response to the World Well being Group. Final month’s instances in Ghana had been the primary recorded in that nation.

The Marburg virus is the pathogen that causes Marburg virus illness in people, well being consultants stated.

There are not any vaccines or antiviral therapies for the illness, medical consultants stated, however hydrating sufferers and treating their particular signs can enhance their possibilities of survival.

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The illness is clinically just like Ebola in its unfold, signs and development, though it’s brought on by a special virus, in response to the W.H.O. In Marburg’s case, fruit bats are thought-about to be the hosts of the virus, although researchers say it doesn’t trigger them sickness. Researchers consider that Ebola is probably going carried by bats or by nonhuman primates, in response to the Facilities for Illness Management and Prevention. Though it has not unfold broadly, Marburg has been lethal, with case fatality charges starting from 24 to 88 p.c, relying on which pressure folks contract and the administration of instances, in response to the W.H.O. The Ebola case fatality charges are practically the identical.

The Marburg virus can unfold via direct contact with blood, secretions or different bodily fluids from contaminated folks, in response to the W.H.O. It might probably additionally unfold via contact with contaminated surfaces and supplies like bedding or clothes.

Marburg may cause extreme viral hemorrhagic fever, which interferes with the blood’s potential to clot. The incubation interval ranges from two to 21 days, and signs start abruptly with excessive fever, extreme headache and extreme malaise, in response to the W.H.O. Different signs can embody muscle aches, diarrhea, nausea, lethargy and bleeding via vomit, feces and from different physique elements.

“Mortality could be very excessive,” stated Dr. John Amuasi, who leads the worldwide well being and infectious illness analysis group on the Kumasi Heart for Collaborative Analysis in Tropical Drugs in Kumasi, Ghana. “And there’s no asymptomatic Marburg.”

A affected person can affirm their situation is Marburg via antibody, antigen and polymerase chain response exams, well being organizations stated.

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There have solely been two instances of Marburg virus illness this 12 months, each reported in Ghana. The individuals who contracted the virus weren’t associated and so they had been in several elements of the Ashanti area of Ghana, Dr. Amuasi stated. They each died.

Each sufferers had been males who labored on farms, he stated. One was a 26-year-old farmhand who had not too long ago been to a special a part of the nation for work, and the opposite was a 56-year-old subsistence farmer. Contact tracing by native authorities led them to conclude that the lads had not been in the identical locations.

Fruit bats, recognized to be the carriers of the virus, are widespread within the Ashanti area.

Greater than 200 folks died in an outbreak in Angola from 2004 to 2005 and greater than 100 died of the illness within the Democratic Republic of Congo from 1998 to 2000, in response to the C.D.C. Different outbreaks of Marburg haven’t concerned as many instances.

In 2021, there was one case in Guinea, which resulted in that individual’s dying, and three of 4 individuals who had the illness in Uganda in 2017 additionally died, in response to the C.D.C.

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Consultants wish to understand how the 2 folks contracted the virus in Ghana, stated Dr. Francis Kasolo, the W.H.O. consultant to the nation.

“The present investigation is just not solely specializing in contacts,” Dr. Kasolo stated. “We’re additionally going again to medical information in these areas to see if there have been uncommon occasions when it comes to instances that introduced with signs. That’s the reason we’re holding again in saying that that is only a one-off occasion.”

The C.D.C.’s workplace in Ghana is working with native well being authorities to help with testing and epidemiological investigations, stated Dr. Jonathan Towner, who leads the Virus Host Ecology Part on the C.D.C.

Folks in america are at not at excessive threat for publicity, Dr. Towner stated.

“It’s a really, very low threat likelihood at this level that there might be some vacationers, for instance, coming into the nation with Marburg proper now,” he stated.

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Thus far, Dr. Amuasi stated, the general public well being response has been acceptable and clear. Contacts of the 2 contaminated folks had been monitored, significantly within the 21 days after the 2 died.

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How The Great British Bake Off Host Alison Hammond Lost 150 Lbs Naturally

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How The Great British Bake Off Host Alison Hammond Lost 150 Lbs Naturally


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Alison Hammond’s Weight Loss: How She Shed 150 Lbs | Woman’s World




















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One state leads country in human bird flu with nearly 40 confirmed cases

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One state leads country in human bird flu with nearly 40 confirmed cases

A child in California is presumed to have H5N1 bird flu, according to the San Francisco Department of Public Health (SFDPH).

As of Dec. 23, there had been 36 confirmed human cases of bird flu in the state, according to the California Department of Public Health (CDPH).

This represents more than half of the human cases in the country.

LOUISIANA REPORTS FIRST BIRD FLU-RELATED HUMAN DEATH IN US

The latest pediatric patient, who lives in San Francisco, experienced fever and conjunctivitis (pink eye) as a result of the infection.

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The unnamed patient was not hospitalized and has fully recovered, according to the SFDPH.

A child in California is presumed to have H5N1 bird flu, according to the San Francisco Department of Public Health. (iStock)

The child tested positive for bird flu at the SFDPH Public Health Laboratory. The U.S. Centers for Disease Control and Prevention (CDC) will perform additional tests to confirm the result.

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It is not yet known how the child was exposed to the virus and an investigation is ongoing.

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“I want to assure everyone in our city that the risk to the general public is low, and there is no current evidence that the virus can be transmitted between people,” said Dr. Grant Colfax, director of health, in the press release. 

BIRD FLU PATIENT HAD VIRUS MUTATIONS, SPARKING CONCERN ABOUT HUMAN SPREAD

“We will continue to investigate this presumptive case, and I am urging all San Franciscans to avoid direct contact with sick or dead birds, especially wild birds and poultry. Also, please avoid unpasteurized dairy products.” 

Samuel Scarpino, director of AI and life sciences and professor of health sciences at Northeastern University in Boston, is calling for “decisive action” to protect individuals who may be in contact with infected livestock and also to alert the public about the risks associated with wild birds and infected backyard flocks. 

Chick bird flu test

An infectious diseases expert called for “decisive action” to alert the public about the risks associated with wild birds and infected backyard flocks.  (iStock)

“While I agree that the risk to the broader public remains low, we continue to see signs of escalating risk associated with this outbreak,” he told Fox News Digital.

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Experts have warned that the possibility of mutations in the virus could enable person-to-person transmission.

     

“While the H5N1 virus is currently thought to only transmit from animals to humans, multiple mutations that can enhance human-to-human transmission have been observed in the severely sick American,” Dr. Jacob Glanville, CEO of Centivax, a San Francisco biotechnology company, told Fox News Digital.

Split image of cows and bird flu vial

As of Jan. 10, there have been a total of 707 infected cattle in California, per reports from the California Department of Food and Agriculture. (iStock)

“This highlights the requirement for vigilance and preparation in the event that additional mutations create a human-transmissible pandemic strain.”

As of Jan. 10, there have been a total of 707 infected cattle in California, per reports from the California Department of Food and Agriculture (CDFA).

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In the last 30 days alone, the virus has been confirmed in 84 dairy farms in the state.

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Chronic Pain Afflicts Billions of People. It’s Time for a Revolution.

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Chronic Pain Afflicts Billions of People. It’s Time for a Revolution.

“In the beginning, everyone thought they were going to find this one breakthrough pain drug that would replace opioids,” Gereau said. Increasingly, though, it’s looking like chronic pain, like cancer, could end up having a range of genetic and cellular drivers that vary both by condition and by the particular makeup of the person experiencing it. “What we’re learning is that pain is not just one thing,” Gereau added. “It’s a thousand different things, all called ‘pain.’”

For patients, too, the landscape of chronic pain is wildly varied. Some people endure a miserable year of low-back pain, only to have it vanish for no clear reason. Others aren’t so lucky. A friend of a friend spent five years with extreme pain in his arm and face after roughhousing with his son. He had to stop working, couldn’t drive, couldn’t even ride in a car without a neck brace. His doctors prescribed endless medications: the maximum dose of gabapentin, plus duloxetine and others. At one point, he admitted himself to a psychiatric ward, because his pain was so bad that he’d become suicidal. There, he met other people who also became suicidal after years of living with terrible pain day in and day out.

The thing that makes chronic pain so awful is that it’s chronic: a grinding distress that never ends. For those with extreme pain, that’s easy to understand. But even less severe cases can be miserable. A pain rating of 3 or 4 out of 10 sounds mild, but having it almost all the time is grueling — and limiting. Unlike a broken arm, which gets better, or tendinitis, which hurts mostly in response to overuse, chronic pain makes your whole world shrink. It’s harder to work, and to exercise, and even to do the many smaller things that make life rewarding and rich.

It’s also lonely. When my arms first went crazy, I could barely function. But even after the worst had passed, I saw friends rarely; I still couldn’t drive more than a few minutes, or sit comfortably in a chair, and I felt guilty inviting people over when there wasn’t anything to do. As Christin Veasley, director and co-founder of the Chronic Pain Research Alliance, puts it: “With acute pain, medications, if you take them, they get you over a hump, and you go on your way. What people don’t realize is that when you have chronic pain, even if you’re also taking meds, you rarely feel like you were before. At best, they can reduce your pain, but usually don’t eliminate it.”

A cruel Catch-22 around chronic pain is that it often leads to anxiety and depression, both of which can make pain worse. That’s partly because focusing on a thing can reinforce it, but also because emotional states have physical effects. Both anxiety and depression are known to increase inflammation, which can also worsen pain. As a result, pain management often includes cognitive behavioral therapy, meditation practice or other coping skills. But while those tools are vital, it’s notoriously hard to reprogram our reactions. Our minds and bodies have evolved both to anticipate pain and to remember it, making it hard not to worry. And because chronic pain is so uncomfortable and isolating, it’s also depressing.

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