Health
Do Cancer Centers Push Too Many Tests?
Say a postcard arrives within the mail, a reminder to make an appointment for a mammogram. Or a major care physician orders a PSA take a look at to display a person for prostate most cancers, or tells him that due to his years of smoking, he ought to be screened for lung most cancers.
These sufferers, making an attempt to be told prospects, could look on-line for a most cancers middle to study extra about screening, when it is suggested and for whom.
It won’t be the perfect transfer. Medical societies and the unbiased U.S. Preventive Companies Activity Pressure publish tips about who ought to be screened for lung, prostate and breast cancers and the way incessantly, amongst many different prevention suggestions. However web sites for most cancers facilities typically diverge from these suggestions, in keeping with three research revealed just lately in JAMA Inner Drugs.
Researchers discovered that some websites mentioned the advantages of screening however mentioned little in regards to the harms and dangers. Some supplied suggestions in regards to the age at which to start out screening however glossed over when to cease — an necessary piece of knowledge for older adults.
“If we acknowledge that these web sites are necessary sources of knowledge, based mostly on screening in keeping with the rules we’ve got room for enchancment,” mentioned Dr. Behfar Ehdaie, a urologist at Memorial Sloan Kettering Most cancers Middle in New York and an writer of the research on prostate most cancers screening suggestions.
Screening refers to assessments for sufferers with no signs or proof of illness, together with prostate-specific antigen assessments, mammograms, colonoscopies and CT scans.
The researchers analyzed greater than 600 most cancers middle web sites that supplied suggestions for prostate screening, and located that greater than one-quarter really useful that each one males be screened. Greater than three-quarters didn’t specify an age at which to cease routine testing.
But tips from each the Preventive Companies Activity Pressure and the American Urological Affiliation state that males over 70 shouldn’t be routinely screened, as a result of, in keeping with the Activity Pressure tips, “the potential advantages don’t outweigh the anticipated harms.”
For males aged 55 to 69, each teams urge particular person choices after a dialogue with a clinician about advantages and harms. Neither group, although, recommends routine screening for youthful males at common danger.
Furthermore, the research reported, 62 % of most cancers middle web sites didn’t embody data on the potential harms of screening. As a result of prostate most cancers grows slowly, it typically causes no issues. However detection and therapy can result in issues from surgical procedure or radiation, together with decrease high quality of life from incontinence and sexual dysfunction.
New Developments in Most cancers Analysis
Progress within the subject. Lately, developments in analysis have modified the method most cancers is handled. Listed here are some latest updates:
The surveys discovered related issues on web sites discussing different most cancers screenings. In a research of over 600 breast most cancers facilities, greater than 80 % of these recommending a beginning age and intervals for screening mammograms have been at odds with tips. The research didn’t tackle whether or not the web sites included data on when to cease.
The Preventive Companies Activity Pressure’s 2016 tips, that are at the moment being up to date, advocate screening mammograms each different yr for girls aged 50 to 74; it discovered inadequate proof of profit and harms for these 75 and older. The American Most cancers Society recommends annual or biennial screening for girls over 55 at common danger, so long as they’ve a 10-year life expectancy.
Lung most cancers screening, nevertheless, is really useful just for these at excessive danger due to smoking historical past and older age. Right here, too, an evaluation of 162 most cancers middle web sites confirmed that about half didn’t tackle potential harms.
“We predict it’s necessary to current a balanced account,” mentioned Dr. Daniel Jonas, an internist at Ohio State College School of Drugs and senior writer of the research. “It’s honest to say they may do a greater job.”
Issues about overtesting and overtreatment of sure cancers in older adults have endured for years. “The harms of screening happen early,” mentioned Dr. Mara Schonberg, an internist and well being care researcher at Beth Israel Deaconess Medical Middle in Boston. However the advantages of screening can accrue years later; older sufferers with different well being issues could not reside lengthy sufficient to expertise them.
With mammography, as an illustration, harms embody false positives, resulting in repeat mammograms or biopsies, the psychological penalties of which may proceed for months, Dr. Schonberg’s analysis has proven.
And whereas most breast cancers identified in girls over 70 are very low danger and would possibly by no means progress, “almost all are handled with surgical procedure,” Dr. Schonberg mentioned, and generally thereafter with radiation and endocrine medicine, all of which may have destructive uncomfortable side effects.
As for advantages, the info confirmed that 1,000 girls aged 50 to 74 must bear mammography for almost 11 years to stop one loss of life from breast most cancers.
Why would some most cancers middle web sites omit prospects like false positives, repeat testing, radiation publicity or the aftereffects of surgical procedure? Why don’t they embody data on what number of lives screenings really save at specific ages?
“Within the U.S. well being care system, the extra procedures you do, the extra you receives a commission,” mentioned Dr. Alexander Smith, a palliative drugs specialist and geriatrics researcher on the College of California, San Francisco. Radiology, which is required for each lung and breast screenings, “is without doubt one of the greatest moneymakers for well being programs,” he famous.
Some web sites could have been developed by entrepreneurs with little enter from well being professionals, Dr. Jonas added. Speaking about dangers might discourage sufferers from clicking the “Make an Appointment” button.
However, it may be onerous to dissuade older sufferers from screening, even when analysis exhibits little profit.
Dr. Schonberg has developed and examined determination aids — pamphlets to assist girls over 75 and their docs attain evidence-based conclusions about mammograms.
To some extent, they work. Older girls who obtain the pamphlets are extra educated and extra apt to debate advantages and dangers with their docs; they’re much less inclined to proceed screening. However over 18 months, about half of ladies who obtained determination aids received mammograms anyway, as did 60 % of those that hadn’t.
Dr. Schonberg defined it as behavior or “the necessity for reassurance.” Sufferers may overestimate their danger stage; the typical 75-year-old lady has a 2 % probability of a breast most cancers analysis over 5 years, she identified.
Furthermore, screening decisions contain a problem some older sufferers (and docs) want to keep away from: life expectancy. The American Most cancers Society and a few medical teams use 10-year life expectancy, somewhat than age cutoffs, as tips for when older sufferers can cease screening.
“Prognosis is without doubt one of the key components in determination making,” Dr. Smith mentioned. “Are sufferers going to reside lengthy sufficient to expertise the advantages?” That may be an uncomfortable dialog involving age, well being and mortality.
How ought to older adults inform themselves about most cancers screenings? Along with discussing professionals and cons with their docs — Medicare requires such a go to earlier than it’s going to cowl a lung most cancers screening — sufferers can go to the U.S. Preventive Companies Activity Pressure web site for the most recent assessments.
They will additionally use ePrognosis, a web-based information that Dr. Schonberg, Dr. Smith and colleagues at U.C.S.F. developed a decade in the past. Most guests are well being care professionals, however sufferers may use the location’s calculators to find out whether or not they’re more likely to profit from breast and colon most cancers screenings. They will use questionnaires that assist to find out their possible life expectancy, in addition to a number of determination aids.
In fact, sufferers can seek the advice of most cancers middle web sites, too — however with an eye fixed to what could also be lacking.
Health
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Health
One state leads country in human bird flu with nearly 40 confirmed cases
A child in California is presumed to have H5N1 bird flu, according to the San Francisco Department of Public Health (SFDPH).
As of Dec. 23, there had been 36 confirmed human cases of bird flu in the state, according to the California Department of Public Health (CDPH).
This represents more than half of the human cases in the country.
LOUISIANA REPORTS FIRST BIRD FLU-RELATED HUMAN DEATH IN US
The latest pediatric patient, who lives in San Francisco, experienced fever and conjunctivitis (pink eye) as a result of the infection.
The unnamed patient was not hospitalized and has fully recovered, according to the SFDPH.
The child tested positive for bird flu at the SFDPH Public Health Laboratory. The U.S. Centers for Disease Control and Prevention (CDC) will perform additional tests to confirm the result.
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It is not yet known how the child was exposed to the virus and an investigation is ongoing.
“I want to assure everyone in our city that the risk to the general public is low, and there is no current evidence that the virus can be transmitted between people,” said Dr. Grant Colfax, director of health, in the press release.
BIRD FLU PATIENT HAD VIRUS MUTATIONS, SPARKING CONCERN ABOUT HUMAN SPREAD
“We will continue to investigate this presumptive case, and I am urging all San Franciscans to avoid direct contact with sick or dead birds, especially wild birds and poultry. Also, please avoid unpasteurized dairy products.”
Samuel Scarpino, director of AI and life sciences and professor of health sciences at Northeastern University in Boston, is calling for “decisive action” to protect individuals who may be in contact with infected livestock and also to alert the public about the risks associated with wild birds and infected backyard flocks.
“While I agree that the risk to the broader public remains low, we continue to see signs of escalating risk associated with this outbreak,” he told Fox News Digital.
Experts have warned that the possibility of mutations in the virus could enable person-to-person transmission.
“While the H5N1 virus is currently thought to only transmit from animals to humans, multiple mutations that can enhance human-to-human transmission have been observed in the severely sick American,” Dr. Jacob Glanville, CEO of Centivax, a San Francisco biotechnology company, told Fox News Digital.
“This highlights the requirement for vigilance and preparation in the event that additional mutations create a human-transmissible pandemic strain.”
As of Jan. 10, there have been a total of 707 infected cattle in California, per reports from the California Department of Food and Agriculture (CDFA).
For more Health articles, visit www.foxnews.com/health
In the last 30 days alone, the virus has been confirmed in 84 dairy farms in the state.
Health
Chronic Pain Afflicts Billions of People. It’s Time for a Revolution.
“In the beginning, everyone thought they were going to find this one breakthrough pain drug that would replace opioids,” Gereau said. Increasingly, though, it’s looking like chronic pain, like cancer, could end up having a range of genetic and cellular drivers that vary both by condition and by the particular makeup of the person experiencing it. “What we’re learning is that pain is not just one thing,” Gereau added. “It’s a thousand different things, all called ‘pain.’”
For patients, too, the landscape of chronic pain is wildly varied. Some people endure a miserable year of low-back pain, only to have it vanish for no clear reason. Others aren’t so lucky. A friend of a friend spent five years with extreme pain in his arm and face after roughhousing with his son. He had to stop working, couldn’t drive, couldn’t even ride in a car without a neck brace. His doctors prescribed endless medications: the maximum dose of gabapentin, plus duloxetine and others. At one point, he admitted himself to a psychiatric ward, because his pain was so bad that he’d become suicidal. There, he met other people who also became suicidal after years of living with terrible pain day in and day out.
The thing that makes chronic pain so awful is that it’s chronic: a grinding distress that never ends. For those with extreme pain, that’s easy to understand. But even less severe cases can be miserable. A pain rating of 3 or 4 out of 10 sounds mild, but having it almost all the time is grueling — and limiting. Unlike a broken arm, which gets better, or tendinitis, which hurts mostly in response to overuse, chronic pain makes your whole world shrink. It’s harder to work, and to exercise, and even to do the many smaller things that make life rewarding and rich.
It’s also lonely. When my arms first went crazy, I could barely function. But even after the worst had passed, I saw friends rarely; I still couldn’t drive more than a few minutes, or sit comfortably in a chair, and I felt guilty inviting people over when there wasn’t anything to do. As Christin Veasley, director and co-founder of the Chronic Pain Research Alliance, puts it: “With acute pain, medications, if you take them, they get you over a hump, and you go on your way. What people don’t realize is that when you have chronic pain, even if you’re also taking meds, you rarely feel like you were before. At best, they can reduce your pain, but usually don’t eliminate it.”
A cruel Catch-22 around chronic pain is that it often leads to anxiety and depression, both of which can make pain worse. That’s partly because focusing on a thing can reinforce it, but also because emotional states have physical effects. Both anxiety and depression are known to increase inflammation, which can also worsen pain. As a result, pain management often includes cognitive behavioral therapy, meditation practice or other coping skills. But while those tools are vital, it’s notoriously hard to reprogram our reactions. Our minds and bodies have evolved both to anticipate pain and to remember it, making it hard not to worry. And because chronic pain is so uncomfortable and isolating, it’s also depressing.
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