Health
Colorectal cancer is showing up in younger people and at more advanced stages: study
Superior stage colorectal most cancers (CRC) instances are on the rise and the illness is being found amongst youthful sufferers extra steadily, in keeping with Colorectal Most cancers Statistics 2023, a brand new report on most cancers details and traits by the American Most cancers Society (ACS), which is headquartered in Atlanta.
Though deaths associated to CRC are persevering with to say no, the report indicated the disturbing development throughout the panorama of combating this illness.
Notably, this consists of the superior stage of most cancers on the time of analysis and the affected person’s age at which it is identified.
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The incidence of superior stage CRC illness now happens in three out of 5 individuals, whereas one out of each 5 CRC diagnoses are made in individuals beneath 55 years previous, in keeping with the examine’s investigators.
Additionally, people who find themselves natives of Alaska had the very best price and mortality — nearly 4 occasions increased than these of non‐Hispanic White people, in keeping with the report.
It was printed on Wednesday, March 1, within the journal CA: A Most cancers Journal for Clinicians and within the publication Colorectal Most cancers Info & Figures 2023-2025 on most cancers.org.
“We all know charges are rising in younger individuals, but it surely’s alarming to see how quickly the entire affected person inhabitants is shifting youthful, regardless of shrinking numbers within the general inhabitants,” Rebecca Siegel, senior scientific director, surveillance analysis on the American Most cancers Society and lead writer of the report mentioned in a information launch.
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“The development towards extra superior illness in individuals of all ages can also be stunning and will inspire everybody 45 and older to get screened,” Siegel mentioned within the launch as nicely.
“The development towards extra superior illness in individuals of all ages can also be stunning and will inspire everybody 45 and older to get screened.”
The researchers collected knowledge from 50 states and the District of Columbia.
The info was obtainable via 2019 from the Surveillance, Epidemiology and Finish Outcomes (SEER) program of the Nationwide Most cancers Institute and the Nationwide Program of Most cancers Registries of the Facilities for Illness Management and Prevention, as supplied by the North American Affiliation of Central Most cancers Registries.
The researchers additionally checked out nationwide mortality knowledge obtainable via 2020 that was supplied by the Nationwide Middle for Well being Statistics, in keeping with the report.
Total, CRC mortality declined by 2% yearly from 2011 to 2020, but there was an 0.5%–3% annual enhance in mortality in people youthful than 50 years previous and in Native Individuals beneath 65 years of age, in keeping with the examine.
Regardless of these general declines, a analysis of CRC is being seen extra steadily in these of a youthful age and at a extra superior stage.
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The investigators famous that people within the U.S. identified with advanced-stage colorectal most cancers elevated from 52% within the mid-2000s to 60% in 2019.
“We’ve got to deal with why the charges in younger adults proceed to development within the mistaken path.”
The variety of CRC instances in people beneath 55 years previous almost doubled from 11% in 1995 to twenty% in 2019.
That may be a leap from 1 in 10 individuals to 1 in 5, in keeping with the discharge.
“We’ve got to deal with why the charges in younger adults proceed to development within the mistaken path,” Dr. Ahmedin Jemal, senior vice chairman, surveillance and well being fairness science on the American Most cancers Society and senior writer of the examine, mentioned in a information launch.
“We have to make investments extra in analysis to uncover the causes of the rising traits and to find new therapy for advanced-stage ailments to cut back the morbidity and mortality related to this illness on this younger inhabitants, who’re elevating households and supporting different members of the family.”
Colorectal Most cancers Consciousness Month is noticed in March to emphasize the significance of screening for this type of most cancers.
‘Extremely regarding knowledge’
The researchers mentioned an estimated 153,020 individuals will likely be identified with CRC within the U.S., and that some 52,550 individuals will die from the illness in 2023.
“These extremely regarding knowledge illustrate the pressing have to spend money on focused most cancers analysis research devoted to understanding and stopping early-onset colorectal most cancers,” Dr. Karen E. Knudsen, CEO of the American Most cancers Society, mentioned in a information launch.
“The shift to analysis of extra superior illness additionally underscores the significance of screening and early detection, which saves lives.”
The report revealed that CRC instances declined quickly in individuals 50 and older in the course of the 2000s. This was attributed to elevated screening with colonoscopy, which specialists say can assist stop most cancers by eradicating precancerous growths or polyps.
The examine authors discovered, nonetheless, that progress has slowed over the previous decade, which might be partially as a result of development in rising instances in youthful people, the examine famous.
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The report discovered that the 65 and older age group confirmed a decline in incidence charges since 2011 and that these charges stabilized within the 50-64 yr previous cohort.
Nonetheless, a disturbing development confirmed an elevated incidence price by 2% per yr in individuals youthful than 50 years of age, in addition to in individuals ages 50 to 54 years previous.
Colonoscopies had been usually beneficial at age 50, however in recent times, that quantity was modified to age 45 in average-risk people and earlier if there was household historical past or different threat components.
Most cancers specialists mentioned they’re involved that the diagnoses being made are for extra superior illness phases, through which the most cancers has unfold to lymph nodes and different organs.
In the case of stopping colorectal most cancers, “one of many easiest instruments to inform individuals is to get a colonoscopy after they’re younger,” Dr. Paul Oberstein, M.D., a medical oncologist at NYU Langone Perlmutter Most cancers Middle in New York Metropolis, instructed Fox Information Digital.
Oberstein was not concerned within the examine however commented on the findings.
Colonoscopies had been usually beneficial at age 50, he mentioned, however in recent times, that quantity was modified to age 45 in average-risk people and earlier if there was household historical past or different threat components.
Whereas colonoscopies are the primary normal used to diagnose CRC, new methods to display for this kind of most cancers are wanted, mentioned Oberstein, particularly based mostly on these findings of extra aggressive types identified in a youthful inhabitants.
“We do not really know why rectal most cancers is rising in youthful individuals,” he instructed Fox Information Digital.
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He added, “There are quite a lot of hypotheses. Individuals assume it may need to do with food plan, or with antibiotics, or with publicity to different meals, [such as] processed meals — or you can also make a listing of something. We do not know the reply. And so the problem is that till we all know that reply, it is actually onerous to show it round if you do not know what we’re focusing on.”
Along with acquiring a colonoscopy, sufferers ought to concentrate on indicators of CRC.
They need to converse to their well being care supplier, he mentioned, particularly in the event that they see blood of their stool or have intestinal points that do not resolve.
CRC is the third mostly identified most cancers and the third main reason behind most cancers deaths in each women and men within the U.S., in keeping with the examine.
The American Most cancers Society Most cancers Motion Community (ACS CAN) is constant to advocate for the implementing of insurance policies in every state to assist cowl the price of colonoscopies and get rid of boundaries to colorectal most cancers screening.
Health
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Health
As bird flu spreads, CDC recommends faster 'subtyping' to catch more cases
As cases of H5N1, also known as avian flu or bird flu, continue to surface across the U.S., safety precautions are ramping up.
The U.S. Centers for Disease Control and Prevention (CDC) announced on Thursday its recommendation to test hospitalized influenza A patients more quickly and thoroughly to distinguish between seasonal flu and bird flu.
The accelerated “subtyping” of flu A in hospitalized patients is in response to “sporadic human infections” of avian flu, the CDC wrote in a press release.
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“CDC is recommending a shortened timeline for subtyping all influenza A specimens among hospitalized patients and increasing efforts at clinical laboratories to identify non-seasonal influenza,” the agency wrote.
“Clinicians and laboratorians are reminded to test for influenza in patients with suspected influenza and, going forward, to now expedite the subtyping of influenza A-positive specimens from hospitalized patients, particularly those in an intensive care unit (ICU).”
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The goal is to prevent delays in identifying bird flu infections and promote better patient care, “timely infection control” and case investigation, the agency stated.
These delays are more likely to occur during the flu season due to high patient volumes, according to the CDC.
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Health care systems are expected to use tests that identify seasonal influenza A as a subtype – so if a test comes back positive for influenza A but negative for seasonal influenza, that is an indicator that the detected virus might be novel.
“Subtyping is especially important in people who have a history of relevant exposure to wild or domestic animals [that are] infected or possibly infected with avian influenza A (H5N1) viruses,” the CDC wrote.
In an HHS media briefing on Thursday, the CDC confirmed that the public risk for avian flu is still low, but is being closely monitored.
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The agency spokesperson clarified that this accelerated testing is not due to bird flu cases being missed, as the CDC noted in its press release that those hospitalized with influenza A “probably have seasonal influenza.”
Niels Riedemann, MD, PhD, CEO and founder of InflaRx, a German biotechnology company, said that understanding these subtypes is an “important step” in better preparing for “any potential outbreak of concerning variants.”
“It will also be important to foster research and development of therapeutics, including those addressing the patient’s inflammatory immune response to these types of viruses – as this has been shown to cause organ injury and death during the COVID pandemic,” he told Fox News Digital.
Since 2022, there have been 67 total human cases of bird flu, according to the CDC, with 66 of those occurring in 2024.
The CDC recommends that people avoid direct contact with wild birds or other animals that are suspected to be infected. Those who work closely with animals should also wear the proper personal protective equipment (PPE).
Health
Sick Prisoners in New York Were Granted Parole but Remain Behind Bars
When the letter arrived at Westil Gonzalez’s prison cell saying that he had been granted parole, he couldn’t read it. Over the 33 years he had been locked up for murder, multiple sclerosis had taken much of his vision and left him reliant on a wheelchair.
He had a clear sense of what he would do once freed. “I want to give my testimony to a couple of young people who are out there, picking up guns,” Mr. Gonzalez, 57, said in a recent interview. “I want to save one person from what I’ve been through.”
But six months have passed, and Mr. Gonzalez is still incarcerated outside Buffalo, because the Department of Corrections has not found a nursing home that will accept him. Another New York inmate has been in the same limbo for 20 months. Others were released only after suing the state.
America’s elderly prison population is rising, partly because of more people serving long sentences for violent crimes. Nearly 16 percent of prisoners were over 55 in 2022, up from 5 percent in 2007. The share of prisoners over 65 quadrupled over the same time period, to about 4 percent.
Complex and costly medical conditions require more nursing care, both in prison and after an inmate’s release. Across the country, prison systems attempting to discharge inmates convicted of serious crimes often find themselves with few options. Nursing home beds can be hard to find even for those without criminal records.
Spending on inmates’ medical care is increasing — in New York, it has grown to just over $7,500 in 2021 from about $6,000 per person in 2012. Even so, those who work with the incarcerated say the money is often not enough to keep up with the growing share of older inmates who have chronic health problems.
“We see a lot of unfortunate gaps in care,” said Dr. William Weber, an emergency physician in Chicago and medical director of the Medical Justice Alliance, a nonprofit that trains doctors to work as expert witnesses in cases involving prison inmates. With inmates often struggling to get specialty care or even copies of their own medical records, “things fall through the cracks,” he said.
Dr. Weber said he was recently involved in two cases of seriously ill prisoners, one in Pennsylvania and the other in Illinois, who could not be released without a nursing home placement. The Pennsylvania inmate died in prison and the Illinois man remains incarcerated, he said.
Almost all states have programs that allow early release for inmates with serious or life-threatening medical conditions. New York’s program is one of the more expansive: While other states often limit the policy to those with less than six months to live, New York’s is open to anyone with a terminal or debilitating illness. Nearly 90 people were granted medical parole in New York between 2020 and 2023.
But the state’s nursing home occupancy rate hovers around 90 percent, one of the highest in the nation, making it especially hard to find spots for prisoners.
The prison system is “competing with hospital patients, rehabilitation patients and the general public that require skilled nursing for the limited number of beds available,” said Thomas Mailey, a spokesman for the New York Department of Corrections and Community Supervision. He declined to comment on Mr. Gonzalez’s case or on any other inmate’s medical conditions.
Parolees remain in the state’s custody until their original imprisonment term has expired. Courts have previously upheld the state’s right to place conditions on prisoner releases to safeguard the public, such as barring paroled sex offenders from living near schools.
But lawyers and medical ethicists contend that paroled patients should be allowed to choose how to get their care. And some noted that these prisoners’ medical needs are not necessarily met in prison. Mr. Gonzalez, for example, said he had not received glasses, despite repeated requests. His disease has made one of his hands curl inward, leaving his unclipped nails to dig into his palm.
“Although I’m sympathetic to the difficulty of finding placements, the default solution cannot be continued incarceration,” said Steven Zeidman, director of the criminal defense clinic at CUNY School of Law. In 2019, one of his clients died in prison weeks after being granted medical parole.
New York does not publish data on how many inmates are waiting for nursing home placements. One 2018 study found that, between 2013 and 2015, six of the 36 inmates granted medical parole died before a placement could be found. The medical parole process moves slowly, the study showed, sometimes taking years for a prisoner to even get an interview about their possible release.
Finding a nursing home can prove difficult even for a patient with no criminal record. Facilities have struggled to recruit staff, especially since the coronavirus pandemic. Nursing homes may also worry about the safety risk of someone with a prior conviction, or about the financial risk of losing residents who do not want to live in a facility that accepts former inmates.
“Nursing homes have concerns and, whether they are rational or not, it’s pretty easy not to pick up or return that phone call,” said Ruth Finkelstein, a professor at Hunter College who specializes in policies for older adults and reviewed legal filings at The Times’s request.
Some people involved in such cases said that New York prisons often perform little more than a cursory search for nursing care.
Jose Saldana, the director of a nonprofit called the Release Aging People in Prison Campaign, said that when he was incarcerated at Sullivan Correctional Facility from 2010 through 2016, he worked in a department that helped coordinate parolees’ releases. He said he often reminded his supervisor to call nursing homes that hadn’t picked up the first time.
“They would say they had too many other responsibilities to stay on the phone calling,” Mr. Saldana said.
Mr. Mailey, the spokesman for the New York corrections department, said that the agency had multiple discharge teams seeking placement options.
In 2023, Arthur Green, a 73-year-old patient on kidney dialysis, sued the state for release four months after being granted medical parole. In his lawsuit, Mr. Green’s attorneys said that they had secured a nursing home placement for him, but that it lapsed because the Department of Corrections submitted an incomplete application to a nearby dialysis center.
The state found a placement for Mr. Green a year after his parole date, according to Martha Rayner, an attorney who specializes in prisoner release cases.
John Teixeira was granted medical parole in 2020, at age 56, but remained incarcerated for two and a half years, as the state searched for a nursing home. He had a history of heart attacks and took daily medications, including one delivered through an intravenous port. But an assessment from an independent cardiologist concluded that Mr. Teixeira did not need nursing care.
Lawyers with the Legal Aid Society in New York sued the state for his release, noting that during his wait, his port repeatedly became infected and his diagnosis progressed from “advanced” to “end-stage” heart failure.
The Department of Corrections responded that 16 nursing homes had declined to accept Mr. Teixeira because they could not manage his medical needs. The case resolved three months after the suit was filed, when “the judge put significant pressure” on the state to find an appropriate placement, according to Stefen Short, one of Mr. Teixeira’s lawyers.
Some sick prisoners awaiting release have found it difficult to get medical care on the inside.
Steve Coleman, 67, has trouble walking and spends most of the day sitting down. After 43 years locked up for murder, he was granted parole in April 2023 and has remained incarcerated, as the state looks for a nursing home that could coordinate with a kidney dialysis center three times each week.
But Mr. Coleman has not had dialysis treatment since March, when the state ended a contract with its provider. The prison has offered to take Mr. Coleman to a nearby clinic for treatment, but he has declined because he finds the transportation protocol — which involves a strip search and shackles — painful and invasive.
“They say you’ve got to go through a strip search,” he said in a recent interview. “If I’m being paroled, I can’t walk and I’m going to a hospital, who could I be hurting?”
Volunteers at the nonprofit Parole Prep Project, which assisted Mr. Coleman with his parole application, obtained a letter from Mount Sinai Hospital in New York City in June offering to give him medical care and help him transition back into the community.
Still incarcerated two months later, Mr. Coleman sued for his release.
In court filings, the state argued that it would be “unsafe and irresponsible” to release Mr. Coleman without plans to meet his medical needs. The state also said that it had contacted Mount Sinai, as well as hundreds of nursing homes, about Mr. Coleman’s placement and had never heard back.
In October, a court ruled in the prison system’s favor. Describing Mr. Coleman’s situation as “very sad and frustrating,” Justice Debra Givens of New York State Supreme Court concluded that the state had a rational reason to hold Mr. Coleman past his parole date. Ms. Rayner, Mr. Coleman’s lawyer, and the New York Civil Liberties Union appealed the ruling on Wednesday.
Fourteen medical ethicists have sent a letter to the prison supporting Mr. Coleman’s release. “Forcing continued incarceration under the guise of ‘best interests,’ even if doing so is well-intentioned, disregards his autonomy,” they wrote.
Several other states have come up with a different solution for people on medical parole: soliciting the business of nursing homes that specialize in housing patients rejected elsewhere.
A private company called iCare in 2013 opened the first such facility in Connecticut, which now houses 95 residents. The company runs similar nursing homes in Vermont and Massachusetts.
David Skoczulek, iCare’s vice president of business development, said that these facilities tend to save states money because the federal government covers some of the costs through Medicaid.
“It’s more humane, less restrictive and cost-effective,” he said. “There is no reason for these people to remain in a corrections environment.”
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