Health
Can we reverse Alzheimer’s disease? Experts suggest ‘new paradigm’ for combating dementia
With more people dying from Alzheimer’s disease than ever before, experts are emphasizing the importance of early diagnosis and intervention.
The number of fatalities due to the disease increased by 141% between 2000 and 2021, according to the 2024 Alzheimer’s Disease Facts and Figures report.
Also, the number of Americans living with the disease is on the rise as well — up to 6.9 million and counting.
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“As older adults — mostly baby boomers born between 1946 and 1964 — are the fastest-growing segment of the population, and this same demographic is at the highest risk for Alzheimer’s disease and related dementias, it is not entirely surprising that the number of cases continues to grow,” Dr. James Galvin, chief of cognitive neurology and director of the Comprehensive Center for Brain Health at The University of Miami Health System, told Fox News Digital.
The number of fatalities due to the disease increased by 141% between 2000 and 2021, according to the 2024 Alzheimer’s Disease Facts and Figures report. (iStock)
Another factor contributing to the uptick of cases is that the disease is getting detected earlier, he noted — “due to scientific advances in knowledge, diagnostic criteria and laboratory tests that enable health care professionals to make diagnoses with greater surety and accuracy.”
Importance of early detection
Early detection and diagnosis allows the family to plan for future care at a time when the patient is able to express their wishes and desires, Galvin noted.
Also, many of the available medications to reduce symptoms are most effective when started early in the course of the disease, he added.
Patients who are diagnosed early will also have a better chance of enrolling in clinical trials for new medications and diagnostics.
Many of the available medications to reduce symptoms are most effective when started early in the course of Alzheimer’s disease, said one expert. (iStock)
“There are newer medications that have the potential for disease modification that are approved or under consideration for approval, so patients have more treatment options,” Galvin said.
The current medications largely treat symptoms and slow progression of disease — but several trials are underway to test prevention therapies.
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“Specifically, these are monoclonal antibodies against the amyloid beta-protein, the building block of the senile plaques in the Alzheimer’s brain,” Galvin said.
“This is particularly exciting, because rather than being reactive after the disease starts, these new programs are proactive and could potentially have a much greater impact on public health.”
Can Alzheimer’s be reversed?
Dr. Heather Sandison, a leading expert in Alzheimer’s and related dementia care who is based in California, said that in some cases, the disease can be slowed or even reversed.
“The ways for individuals to potentially reverse Alzheimer’s vary, because the causes of Alzheimer’s vary from person to person,” Sandison, author of the upcoming book “Reversing Alzheimer’s: The New Toolkit to Improve Cognition and Protect Brain Health,” told Fox News Digital.
Early detection and diagnosis allows the family to plan for future care at a time when the patient is able to express their wishes and desires, a doctor noted. (iStock)
“Instead of thinking of one way or one of two ways, I propose an entirely new paradigm of thinking about the causes of Alzheimer’s disease — identifying them for the individual and creating a targeted, precise approach to treatment.”
One person, for example, may have Alzheimer’s that is associated with genetic predisposition, high blood sugar and a history of strokes, she noted.
“The choices you make each day about what you put in your mouth, how much you move and what time you get to bed have the biggest impact on your long-term brain health.”
Another individual may have Alzheimer’s caused by the inhalation of toxins from environmental pollution, obstructive sleep apnea reducing the oxygen supply, and a history of traumatic brain injuries.
Someone else may have all of these factors.
“We would treat these individuals differently,” Sandison said.
“The way for an individual to potentially reverse Alzheimer’s varies, because the causes of Alzheimer’s vary from person to person,” an expert said. (iStock)
Regardless of risk factors, Sandison said the best ways to prevent Alzheimer’s are to eat a diet high in vegetables, good fats and proteins, while also getting regular vigorous exercise, quality sleep and daily stress management practices.
“The choices you make each day about what you put in your mouth, how much you move and what time you get to bed have the biggest impact on your long-term brain health,” she said.
Like any complex system, the brain and body require a “homeodynamic balance” to function well, according to Sandison.
“Imbalance — too much, too little, in the wrong place, at the wrong time — will create dysfunction and, in the case of the body and brain, disease,” she warned.
“The primary causes of imbalance in the brain include toxins, nutrients, stressors, structure, infections and signaling.”
The number of Americans living with Alzheimer’s disease has risen to 6.9 million. Like any complex system, the brain and body require a “homeodynamic balance” to function well, said one expert. (iStock)
With her reversal techniques, Sandison said she sees the best results with patients who are younger than 75, have MoCA (Montreal Cognitive Assessment) scores of 18 and above, and have a supportive network of loved ones around them, “so they can dive fully into the lifestyle changes.”
She added, “That being said, we have seen miraculous results with patients in their 80s with single-digit MoCA scores.”
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“You don’t have to be perfect, but in order to get results, you need to be willing and able to make some changes,” Sandison continued.
“If you have that, there is room for hope, no matter how much the disease has progressed.”
To her patients, Sandison recommends combining lifestyle recommendations with conventional medicine.
“Diet, lifestyle and functional medicine approaches are best used collaboratively with a primary care provider and neurologist on your team,” she said.
“I am hopeful that in the future, we will use the plaque-busting drugs to reduce structural changes in the brain … in combination with the multi-pronged approach to reversing Alzheimer’s.”
‘Connection over correction’
Sandison coined the “connection over correction” approach as a way of helping caregivers deal with what can often feel like an “overwhelming burden.”
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“There are complex emotions — ranging from joy and gratitude for the precious time with a loved one to grief and despair as you lose them slowly,” she said.
“The physical, financial and emotional toll adds up.”
Regardless of what risk factors someone has, experts recommend eating a diet high in vegetables, good fats and proteins combined with regular vigorous exercise to help reduce dementia risk. (iStock)
One way to reduce the burden is to accept that your loved one has changed and stop correcting them, according to Sandison.
“Focus your energy on connecting with them in a way that honors their current capacity,” she advised.
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“If they make a mistake with a word or repeat a question or miss an appointment … make accommodations and focus on the positive aspects of the day, not dwelling on or emphasizing the mistake.”
The “connection over correction” approach is a way of helping caregivers deal with what can often feel like an “overwhelming burden,” an expert said. (iStock)
Having compassion for loved ones with dementia and understanding they have a disease they cannot control can help to reframe these frustrating situations, she said.
“We all function best when we are experiencing connections with others and when we can avoid the unnecessary stress of feeling we are wrong or as if we have displeased someone,” Sandison added.
The biggest myth surrounding brain health, she said, is that nothing can be done to prevent or reverse dementia or Alzheimer’s.
“That just isn’t true,” she said. “It’s almost overwhelming how much you can do to optimize cognitive function at any stage of life.”
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Health
Dr Oz warns Medicare scammers are stealing billions — and your personal information could be next
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Washington, D.C. – Medicare fraud is a multibillion-dollar problem that government officials say threatens both taxpayer dollars and Americans’ personal identities.
In a July 6 interview with Fox News Digital at the Great American State Fair in Washington, D.C., Dr. Mehmet Oz warned that every dollar stolen through Medicare fraud is a dollar taxpayers lose – a problem that has worsened since the COVID pandemic.
“If I had to just pick one thing to focus on to make healthcare more affordable in America, I’d go to health fraud and all the waste and abuse that accompanies it,” said Oz, who is the administrator of the Centers for Medicare & Medicaid Services. “And just to put this in perspective, we think it’s about $100 billion a year.”
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Medicare fraud can include billing for services that were never provided, overcharging for medical equipment, using stolen patient or doctor information, or performing unnecessary procedures, according to the U.S. Government Accountability Office.
CMS administrator Dr. Mehmet Oz is pictured on stage at the Great American State Fair in Washington, D.C., on July 6, 2026. (Angelica Stabile/Fox News Digital)
As the Trump administration ramped up efforts to combat fraud, CMS reported $41.9 billion in Medicare program integrity savings in 2025, up 59% from $26.3 billion in 2024.
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Medicare fraud not only harms the federal budget and steals from taxpayers, but exposes seniors to identity theft, unnecessary care, higher premiums and reduced access, Oz cautioned.
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Removing corruption from the healthcare system will have the greatest impact among seniors, since “so much of the fraud is perpetrated against them,” the administrator said.
“I’m talking about people tricking seniors to give up their Medicare beneficiary numbers, which is like a credit card basically,” he said. “These scammers can take those numbers and use them for all kinds of illegitimate purposes.”
“If I had to just pick one thing to focus on to make healthcare more affordable in America, I’d go to health fraud and all the waste and abuse that accompanies it,” said Oz. (Fox News Digital)
“People are stealing from you by pretending to send you drugs you don’t want, wheelchairs you don’t need, [and] services you never asked for or don’t benefit from,” Oz added.
To prevent this, he shared his top advice for seniors: Do not give your Medicare beneficiary number to anybody, do not answer questions on a phone call from an unknown person and do not give away personal information.
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“These scammers are calling seniors, tricking them, and once they have key information, they can steal it,” he said. “And I won’t know it and you won’t know it.”
“We want to protect people who need these programs the most,” Oz went on. “You do that by making sure scoundrels don’t corrupt the systems and steal money out of the till that is designed to help folks in dire straits when they’re vulnerable and in need of services.”
Seniors should never share their Medicare information with unknown people, the administrator advised. (iStock)
Removing fraud could “double the life expectancy of the trust fund that makes all this possible,” Oz predicted.
“If you’re worried about Medicare being there when you’re ready to retire in a couple decades, depending on how old you are, and you’re concerned that it might not last because of all the fraud that’s hitting it … you’ve got a good [reason to] worry,” he said.
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“If we take the fraud out, we could double the life expectancy, which means you, your kids, your kids’ kids … they could all benefit from this beautiful safety net program.”
Health
Common gym supplement could help fight depression, new research suggests
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Creatine, the common muscle-building supplement, may help improve depression symptoms, new research suggests.
A systematic review, published in Genomic Press’ Brain Medicine, found that creatine monohydrate may be beneficial as an add-on treatment for major depressive disorder, although the evidence remains preliminary.
The Canada-based researchers analyzed data from five randomized controlled trials, evaluating the impact of creatine monohydrate intake on mental health.
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Four of the trials studied major depressive disorder, and another looked at bipolar disorder with a current depressive episode.
In one trial of women with depression who took 5 grams of creatine per day, plus the antidepressant escitalopram, there was greater improvement after eight weeks. Another study revealed benefit when creatine was added to cognitive behavioral therapy.
One study saw benefit when creatine was added to cognitive behavioral therapy. (iStock)
Other studies involving teen girls found no benefit from a variety of creatine dosages after eight weeks. The bipolar depression study also found no significant improvements when 6 grams of creatine was added to medication after six weeks.
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In a press release, the researchers said previous studies have found that people with mood disorders process creatine differently in the brain. Because creatine helps produce energy, some scientists believe disruptions in this process may contribute to depression.
Although creatine has also been associated with boosting dopamine and serotonin, which most antidepressants target, the authors stressed that the link between brain creatine and mood “remains correlational,” as depression has “many moving parts.”
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Lead study author Bassam Jeryous Fares, a student in the Faculty of Medicine at the University of Ottawa, commented in a statement that the signal is “interesting, but not a verdict.”
“Two trials pointed one way and three pointed another,” he said. “That is not the kind of evidence on which you change clinical practice. It is the kind that tells you the question is worth further exploration.”
Although creatine has also been associated with boosting dopamine and serotonin, which most antidepressants target, the authors stressed that the link between brain creatine and mood “remains correlational.” (iStock)
Nicholas Fabiano, corresponding author and a psychiatry resident at the University of Ottawa, added in the same press release that creatine “appears to be a safe intervention,” noting that side effects were limited to mild stomach pain.
“We cannot yet reliably say that creatine helps with depressive symptoms or if the findings are generalizable to everyone,” he added as a caveat.
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Dr. Thea Gallagher, psychologist and director of wellness programs at NYU Langone, said that although creatine is best known for supporting muscle performance, it also helps the brain produce and use energy.
“Researchers believe that some people with depression may have alterations in brain energy metabolism, and creatine could help support these energy-producing pathways,” Gallagher, who was not involved in the study, told Fox News Digital. “There is also emerging evidence that it may influence neurotransmitters and reduce oxidative stress and inflammation, although these mechanisms are still being investigated.”
Creatine should be considered a “promising addition” to depression treatments, a doctor said. (iStock)
The research suggests that creatine may be most helpful when combined with established depression treatments rather than as a replacement, Gallagher emphasized.
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“This research is encouraging because it adds to a growing body of evidence suggesting that supporting brain energy metabolism may be another pathway for improving depression symptoms,” she said.
“It’s exciting whenever we identify another potential tool that could complement existing treatments, particularly one that is relatively inexpensive and widely available.”
Limitations and caveats
The new study is a review of prior research rather than a new clinical trial, which can pose a limitation, the researchers acknowledged, adding that “larger, well-controlled trials are still needed.”
Gallagher noted that creatine should be considered as a potentially promising addition to treatment, rather than a substitute for psychotherapy, antidepressant medication, regular exercise or healthy sleep habits.
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“While creatine has a strong safety profile for most healthy adults, it’s still important to talk with your healthcare provider before starting any supplement — particularly if you have kidney disease, are pregnant or have other medical conditions,” she advised.
For those experiencing signs of depression, Gallagher recommends seeking evidence-based mental healthcare.
“While creatine has a strong safety profile for most healthy adults, it’s still important to talk with your healthcare provider before starting any supplement – particularly if you have kidney disease, are pregnant or have other medical conditions,” a doctor advised. (iStock)
The doctor noted that depression is a “highly heterogeneous condition, so we still don’t know which patients are most likely to benefit or what the optimal treatment approach looks like.”
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Gallagher also cautioned that supplements have been known to generate “early enthusiasm” before larger studies have revealed “more modest effects.”
“Right now, I’d describe creatine as promising but not definitive,” she concluded. “It’s an area that deserves continued research, but it’s not something people should view as a standalone treatment for depression.”
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