Connect with us

Health

AI blood test could detect Parkinson's disease up to 7 years before symptoms: 'Particularly promising'

Published

on

AI blood test could detect Parkinson's disease up to 7 years before symptoms: 'Particularly promising'

A new blood test could reveal Parkinson’s diagnoses up to seven years before symptoms emerge.

Researchers from University College London and University Medical Center Goettingen in Germany used artificial intelligence to develop the test.

The study, which was published in the journal Nature Communications, included 72 patients with rapid eye movement behavior disorder (iRBD), a condition that has been linked to a higher risk of Alzheimer’s.

WHAT IS ARTIFICIAL INTELLIGENCE?

When the researchers used machine learning to analyze blood samples from the patients, they discovered that 79% of them had the same biomarkers as people with Parkinson’s.

Advertisement

A new blood test could reveal Parkinson’s diagnoses up to seven years before symptoms emerge, according to recent research. (iStock)

Over a 10-year follow-up period, the researchers confirmed that 16 of the patients went on to develop Parkinson’s, a movement disorder that affects nearly one million people in the U.S.

“By determining eight proteins in the blood, we can identify potential Parkinson’s patients several years in advance,” said co-first-author Dr. Michael Bartl from the University Medical Center Goettingen in a press release.

MILITARY VETERAN EMBRACES ‘NEW SERVICE’ OF HELPING OTHERS AFTER HIS PARKINSON’S DIAGNOSIS: ‘THERE IS HOPE’

“This means that drug therapies could potentially be given at an earlier stage, which could possibly slow down disease progression or even prevent it from occurring.”

Advertisement

“We have not only developed a test, but can diagnose the disease based on markers that are directly linked to processes such as inflammation and degradation of non-functional proteins. So these markers represent possible targets for new drug treatments.”

Woman blood draw

When the researchers used machine learning to analyze blood samples from the patients, they discovered that 79% of them had the same biomarkers as people with Parkinson’s. (iStock)

Blood tests provide a less invasive alternative to a lumbar puncture (also known as a spinal tap), which has been used more often to diagnose Parkinson’s in clinical research, according to professor David Dexter, director of research at Parkinson’s UK.

“This research, co-funded by Parkinson’s UK, represents a major step forward in the search for a definitive and patient friendly diagnostic test for Parkinson’s,” Dexter said in the release. 

RESEARCHERS FIND SOURCES OF FOUR BRAIN DISORDERS, WHICH COULD LEAD TO NEW TREATMENTS

Looking ahead, the researchers plan to follow the participants to confirm the accuracy of the test, and will also analyze samples from others in the population who have a genetic mutation that puts them at a higher risk of developing Parkinson’s.

Advertisement

“The findings add to an exciting flurry of recent activity toward finding a simple way to test for and measure Parkinson’s.”

“With more work, it may be possible that this blood-based test could distinguish between Parkinson’s and other conditions that have some early similarities, such as multiple systems atrophy or Lewy body dementia,” Dexter said in the release.

“The findings add to an exciting flurry of recent activity toward finding a simple way to test for and measure Parkinson’s.”

Dr. Harvey Castro

Dr. Harvey Castro, a Dallas, Texas-based board-certified emergency medicine physician and national speaker on AI in health care, said the blood test could serve as a model for other diseases. (Dr. Harvey Castro)

Dr. Harvey Castro, a Dallas, Texas-based board-certified emergency medicine physician and national speaker on AI in health care, was not involved in the blood test but spoke to Fox News Digital about its potential impact.

For more Health articles, visit www.foxnews/health

Advertisement

“As an ER physician deeply involved in AI applications in health care, I find this development particularly promising,” Castro said. 

“It exemplifies the potential of AI to diagnose and predict serious health conditions, allowing for earlier and potentially more effective interventions.”

Senior man with nurse

Nearly one million people in the U.S. are living with Parkinson’s disease, according to the Parkinson’s Foundation. (iStock)

This approach could serve as a model for other diseases, Castro suggested.

“Having a tool that provides more time before significant nerve cell damage occurs offers a substantial opportunity to address diseases at very early stages, where traditional diagnostic methods might not detect them,” the doctor said.

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

Advertisement

“This early intervention capability could significantly slow the disease progression.”

Although knowing about a disease in advance can help patients prepare mentally and emotionally, Castro warned that it could be a “double-edged sword.” 

Woman at doctor

“Having a tool that provides more time before significant nerve cell damage occurs offers a substantial opportunity to address diseases at very early stages,” one doctor said. (iStock)

“While some patients may benefit from early knowledge and the ability to plan their lives accordingly, others might prefer not to know about a potential future illness due to the psychological burden it could impose,” he said.

Overall, Castro said, this AI-powered blood test represents a “paradigm shift” in the approach to neurodegenerative diseases like Parkinson’s. 

                                    

Advertisement

“It underscores the importance of integrating advanced technologies into medical practice to enhance patient outcomes and transform health care delivery,” he said.

Fox News Digital reached out to the study researchers for additional comment.

Advertisement
Continue Reading
Advertisement
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Health

“I’m a Dietitian and These Are the 5 Biggest Weight Loss Mistakes People Make”

Published

on

“I’m a Dietitian and These Are the 5 Biggest Weight Loss Mistakes People Make”



Advertisement


Weight Loss Mistakes To Avoid: Dietitian’s 5 Top Tips | Woman’s World
























Advertisement













Advertisement


Use left and right arrow keys to navigate between menu items.


Use escape to exit the menu.

Advertisement
Continue Reading

Health

Some sleep apnea patients see improvement with new breathing tool

Published

on

Some sleep apnea patients see improvement with new breathing tool

Join Fox News for access to this content

Plus special access to select articles and other premium content with your account – free of charge.

By entering your email and pushing continue, you are agreeing to Fox News’ Terms of Use and Privacy Policy, which includes our Notice of Financial Incentive.

Please enter a valid email address.

Having trouble? Click here.

A new solution may be on the horizon for the 30 million people in the U.S. who suffer from sleep apnea.

In a Finland study, a new breathing device showed promising results in reducing symptoms of the disorder, according to researchers.

Advertisement

The device, called WellO2, uses resistance training to strengthen throat muscles and steam breathing to humidify airways.

UNTREATED SLEEP APNEA PRESENTS ‘DISRUPTIVE’ DANGERS TO PEOPLE’S LIVES, INCLUDING HEART ISSUES, SAYS EXPERT

In the small study conducted by University of Turku’s Sleep Research Center, 25 participants with mild to moderate sleep apnea used the device at home twice a day for three months, breathing in and out 30 times per session.

At the end of the study period, the participants reported increased respiratory muscle strength, reduced nighttime breathing interruptions, improved sleep quality and decreased insomnia, according to a press release.

In a Finland study, a new breathing device, shown at right, has shown promising results in reducing symptoms of the disorder, according to researchers. (iStock/WellO)

Advertisement

Snoring occurrences were also reduced.

The findings were presented on June 5 at the Nordic Lung Congress 2024 in Helsinki, Finland.

SLEEP DEPRIVATION DANGERS: HOW PULLING AN ALL-NIGHTER AFFECTS YOUR PHYSICAL AND MENTAL HEALTH

The study will now be peer-reviewed by the scientific congress, then will be published later this year, according to the researchers.

WellO2

The device, called WellO2, uses resistance training to strengthen throat muscles, plus steam breathing to humidify airways. (WellO2)

“Currently, there are no available technologies or medications to treat sleep apnea,” lead author Dr. Usame Al-Rammahi, a doctoral researcher of pulmonary diseases and clinical allergology at the University of Turku, told Fox News Digital.

Advertisement

“Our first data suggest that respiratory muscle training may be the answer that not only alleviates symptoms, but also addresses the underlying cause of OSA by strengthening muscles.”

IS ARTIFICIAL INTELLIGENCE THE SECRET TO BETTER SLEEP?

CPAP (continuous positive airway pressure) is currently the most common treatment for sleep apnea — but about a third of patients struggle to adapt to it, Al-Rammahi noted. 

WellO2 is designed to be used as an add-on therapy with CPAP.

man sleeping in cpap mask

CPAP (continuous positive airway pressure) is right now the most common treatment for sleep apnea, yet about a third of patients struggle to adapt to it. (iStock)

“Even though CPAP should be used as needed, WellO2 training can be used as an additional therapy, since it addresses underlying reasons and may lessen CPAP adverse effects by moistening the airways,” Al-Rammahi told Fox News Digital. 

Advertisement

Limitations of the study

This is a preliminary report and research is currently ongoing, Al-Rammahi said. 

The study also did not include a control group.

“There is no quick fix for respiratory rehabilitation.”

“Nonetheless, given that the study compared their results to each participant’s personal findings, those persons were the controls,” Al-Rammahi said.

“Despite the lack of a control group, the findings remain important. Qualified questionnaires were used, and polysomnography (PSG) was a thorough and trustworthy procedure that provided substantial results.”

Advertisement

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

Dr. Chelsie Rohrscheib, a neuroscientist and sleep specialist at Wesper in New York, was not involved in the study but commented on the device’s potential. 

“Sleep apnea is primarily caused by obstructions in the upper airway that block the flow of oxygen into the lungs,” she said.                                                                                  

Snoring

Approximately 30 million people in the U.S. suffer from sleep apnea. (iStock)

“This device is designed to strengthen the muscles of the upper airway and reduce these obstructions from occurring,” she also told Fox News Digital.

While the device was shown to offer “some improvement” when tested in a small population of patients, Rohrscheib noted that use of the device was only correlated with “moderate improvement” in the number of respiratory events.

Advertisement

For more Health articles, visit www.foxnews/health

“That means it’s not guaranteed to work for every patient or to completely eliminate your sleep apnea symptoms,” she said. 

“Further, the device was not tested in patients with severe sleep apnea — thus, patients should not rely on this device alone for treatment for their sleep apnea without the guidance of a sleep physician.”

WellO2

“Patients should not rely on this device alone for treatment for their sleep apnea without the guidance of a sleep physician,” a sleep expert said. (WellO2 )

Katri Lindberg, a respiratory specialist nurse in Finland who works with WellO2 as a breathing expert, said she recommends WellO2 training regularly for individuals who want to stop snoring or for whom CPAP devices are not suitable for treating sleep apnea. 

“The research results are only preliminary findings from a small study, but they provide strong indications that we have found a rehabilitation tool that can now rehabilitate the symptoms of a large group of people worldwide, rather than merely alleviating them,” Lindberg told Fox News Digital.

Advertisement

          

“The study also indicates that there is no quick fix for respiratory rehabilitation. To remove symptoms and keep them at bay, regular, although relatively small, amounts of respiratory training are needed.”

Continue Reading

Health

Chicago man receives kidney transplant while fully awake, goes home very next day

Published

on

Chicago man receives kidney transplant while fully awake, goes home very next day

Join Fox News for access to this content

You have reached your maximum number of articles. Log in or create an account FREE of charge to continue reading.

By entering your email and pushing continue, you are agreeing to Fox News’ Terms of Use and Privacy Policy, which includes our Notice of Financial Incentive.

Please enter a valid email address.

Having trouble? Click here.

Kidney transplants are not uncommon — the kidney is actually the most frequently transplanted organ in the U.S. — but a Chicago man recently received his in a highly unusual way.

John Nicholas, 28, was awake during the entire procedure, which was performed on May 24 at Northwestern Medicine Hospital. He was discharged the very next day.

Advertisement

Doctors administered a spinal anesthesia shot — similar to what is used for a Cesarean section — instead of general anesthesia, according to a press release from the hospital.

MASSACHUSETTS MAN DIES 2 MONTHS AFTER BECOMING FIRST PERSON TO RECEIVE SUCCESSFUL PIG KIDNEY TRANSPLANT

“This is the first case at Northwestern Medicine where a patient was awake during an entire kidney transplant procedure and went home the next day, basically making this an outpatient procedure,” said Satish Nadig, M.D., PhD, transplant surgeon and director of the Northwestern Medicine Comprehensive Transplant Center, in the release. 

“Inside the operating room, it was an incredible experience being able to show a patient what their new kidney looked like before placing it inside the body,” he added. 

John Nicholas, the patient, is pictured with his surgeons in the operating room after completion of the kidney transplant. (Northwestern Medicine)

Advertisement

“It was incredibly simple and uneventful.”

This type of “awake transplant” could reduce surgical risks and shorten the length of the patient’s hospitalization, doctors say.

“It was an incredible experience, being able to show a patient what their new kidney looked like before placing it inside the body.”

It could also increase access to care for patients who are considered high-risk or have phobias surrounding general anesthesia.

Ideal candidate

Nicholas’ surgery took about two hours, according to the hospital.

Advertisement

He was considered an ideal patient for awake surgery due to his young age, his otherwise good health and his “eagerness to participate,” per the release.

John Nicholas

John Nicholas is pictured awake during his kidney transplant in late May. (Northwestern Medicine)

“It was a pretty cool experience to know what was happening in real time and be aware of the magnitude of what they were doing,” said Nicholas in a statement to Northwestern. 

“At one point during surgery, I recall asking, ‘Should I be expecting the spinal anesthesia to kick in?’ They had already been doing a lot of work and I had been completely oblivious to that fact. Truly, no sensation whatsoever.”

PENNSYLVANIA MOM SEEKS ‘PERFECT MATCH’ BONE MARROW DONOR TO CURE DAUGHTER’S RARE DISORDER: ‘CRUCIAL NEED’

Although Nicholas did receive sedation for comfort, he said he was still aware of what was going on. 

Advertisement

“Especially when they called out my name and told me about certain milestones they had reached,” he noted.

John Nicholas with doctors

Nicholas, center, is pictured after surgery with Dr. Vicente Garcia Tomas, his anesthesiologist, at left, and Dr. Nadig, transplant surgeon, at right.  (Northwestern Medicine)

Nicholas walked out of the hospital on May 25, the day after surgery.

With typical kidney transplants, the recipient remains in the hospital for two to three days.

Saved by a friend

Nicholas’ kidney issues began at age 16 when he was diagnosed with Crohn’s disease, the release stated.

FOUR TEXAS RESIDENTS FOREVER CONNECTED BY TWO KIDNEY DONATIONS IN DIFFERENT CITIES: ‘SUPERBLY TIMED’

Advertisement

After a few years of managing the condition with medication, his kidney function worsened and he required a transplant.

Nicholas’ mother originally planned to donate her kidney, but a breast cancer diagnosis prevented her from doing so, the hospital relayed.

John Nicholas and Pat Wise

Nicholas, at left, is pictured with his donor and best friend, Pat Wise, after surgery. (Northwestern Medicine)

It was Nicholas’ best friend from elementary school, 29-year-old Pat Wise in Alexandria, Virginia, who ultimately donated the life-saving kidney.

‘Another tool in our toolbelt’

Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, was not involved in the surgery but shared his input.

“My opinion is that in most cases, spinal anesthesia presents a reasonable alternative for those at high risk of general anesthesia complications,” Siegel told Fox News Digital. 

Advertisement
John Nicholas during surgery

Nicholas is pictured awake with his care team during his kidney transplant surgery. (Northwestern Medicine)

“Having said that, general anesthesia would be preferred whenever possible for major surgery like this,” said Dr. Siegel, “because control of the airway and breathing is essential, and is much easier if the patient is asleep and on the ventilator.”

  

The doctors at Northwestern credit the patient for helping to advance the field of transplant medicine.

John Nicholas with donor, Pat Wise

Nicholas, left, and donor Wise are pictured at a press conference after the surgery. (Northwestern Medicine)

“When John agreed to be the first known patient at Northwestern Medicine to undergo an awake kidney transplant and be discharged home the next day, he knew the benefits outweighed the risks, and … he’s now helping to move the field of transplantation forward,” said Vinayak Rohan, M.D., transplant surgeon at Northwestern Memorial Hospital, in the release. 

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

Advertisement

“He is an extremely compliant patient who was in tune with his body and willing to push the envelope,” stressing that the patient had faith in the doctors and they, in turn, had faith in him.  

John Nicholas with care team

Nicholas, center, is pictured with his entire care team. “He’s now helping to move the field of transplantation forward,” a surgeon said about the patient. (Northwestern Medicine)

The hospital now plans to establish the AWAKE Program (Accelerated Surgery Without General Anesthesia in Kidney Transplantation) for patients who want or need to pursue surgery without general anesthesia.

For more Health articles, visit www.foxnews/health 

“It really opens up a whole new door and is another tool in our toolbelt for the field of transplantation,” Nadig added.

Fox News Digital reached out to Northwestern Medical for additional input.

Advertisement
Continue Reading

Trending