Health
Aging speeds up 'massively' at two points in one's lifetime, Stanford study finds: ‘Abrupt changes’
Aging may not be quite as gradual as it seems.
A new study from Stanford University in California has revealed that there are two periods when aging seems to accelerate.
These two spurts tend to occur around age 44 and again at age 60, the study found.
11 TIPS FOR ADULTS AGE 65 AND OVER TO ‘LIVE WELL’ OVER TIME, ACCORDING TO GERONTOLOGISTS
In the study, 108 participants ranging from 25 to 75 years old gave blood and biological samples over the course of several years, according to a Stanford University press release.
A new study from Stanford University in California has revealed that there are two periods when aging seems to accelerate. (iStock)
The researchers analyzed more than 135,000 molecules and microorganisms (bacteria, viruses and fungi), finding that most of them don’t change in a “gradual, chronological fashion.”
“We’re not just changing gradually over time; there are some really dramatic changes,” said Michael Snyder, PhD, professor of genetics and the study’s senior author, in the release.
105-YEAR-OLD WOMAN GRADUATES FROM STANFORD UNIVERSITY 83 YEARS AFTER LEAVING CAMPUS: ‘AMAZING’
“It turns out the mid-40s is a time of dramatic change, as is the early 60s. And that’s true no matter what class of molecules you look at.”
The findings were published in the journal Nature Aging last month.
For those in their 60s, age-related changes tend to impact the organs and immune system, according to a doctor. (iStock)
Dr. Brittany Ferri, a New York-based occupational therapist with the National Council on Aging, agreed that aging doesn’t always happen steadily.
“Big changes can happen at certain points in your life,” Ferri, who was not involved in the study, told Fox News Digital. “People tend to experience shifts that will impact their health going forward.”
“Certain phases will bring noticeable shifts in how the body functions.”
In their 40s, people are likely to face more stress or make lifestyle changes that could affect their well-being, and by the 60s, age-related changes will impact the organs and immune system, according to Ferri.
“With aging happening in distinct stages, certain phases will bring noticeable shifts in how the body functions,” she added.
The aging-health connection
These “abrupt changes” can have an impact on people’s health as they age, the study found.
“During your 40s and 60s, key molecules and microbes related to heart health and the immune system change considerably,” Ferri told Fox News Digital after reviewing the findings.
“In your 40s, changes in molecules that affect how your body processes fats and alcohol could raise your risk of heart disease if they’re not managed well,” she went on.
“In your 60s, shifts in your immune system can make you more prone to age-related health problems.”
The researchers noted that they were not surprised by the shift in the early 60s, as this is a time when age-related diseases and conditions tend to emerge. (iStock)
The researchers noted that they were not surprised by the shift in the early 60s, as this is a time when age-related diseases and conditions tend to emerge.
The surge in the mid-40s, however, was not expected. While they initially thought this shift was due to menopause or perimenopause in women, they realized it was also occurring for men at that age.
MEN’S ENERGY AND VITALITY PLUMMETS FOR 6 REASONS. BOOST IT BACK UP THIS WAY
“This suggests that while menopause or perimenopause may contribute to the changes observed in women in their mid-40s, there are likely other, more significant factors influencing these changes in both men and women,” first author Xiaotao Shen, PhD, a former Stanford Medicine postdoctoral scholar, said in the release.
“Identifying and studying these factors should be a priority for future research.”
The researchers emphasized the importance of healthy behaviors, like regular exercise and proper nutrition, to counteract the aging spurts. (iStock)
The main limitation is that these changes could be caused by lifestyle or behavioral factors that tend to emerge in the 40s and 60s, Snyder acknowledged.
Looking ahead, the team plans to conduct further research into these aging spurts.
“I’m a big believer that we should try to adjust our lifestyles while we’re still healthy.”
They also emphasized the importance of healthy behaviors to counteract these changes.
“That could look like increasing exercise to protect your heart and maintain muscle mass at both ages or decreasing alcohol consumption in your 40s as your ability to metabolize alcohol slows,” the researchers wrote.
For those in their 40s, it’s important to eat healthy, manage stress, and cut back on alcohol to support the changes in metabolism and heart health, a doctor advised. (iStock)
Added Snyder, “I’m a big believer that we should try to adjust our lifestyles while we’re still healthy.”
For those in their 40s, it’s important to eat healthy, manage stress, and cut back on alcohol to support the changes in metabolism and heart health, according to Ferri.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
“In your 60s, try to focus on staying active to help boost your immune system and stay at a healthy weight,” she recommended.
For more Health articles, visit www.foxnews.com/health
The Stanford study was funded by the National Institutes of Health and the Stanford Data Science Initiative.
Fox News Digital reached out to the researchers for comment.
Health
The Best Time To Take Turmeric for Weight Loss and How To Maximize Results
Use left and right arrow keys to navigate between menu items.
Use escape to exit the menu.
Sign Up
Create a free account to access exclusive content, play games, solve puzzles, test your pop-culture knowledge and receive special offers.
Already have an account? Login
Health
Doctor reveals what 30 days without alcohol does to the brain and body amid Dry January
NEWYou can now listen to Fox News articles!
After a season of bingeing and drinking, your body may feel like it needs a break from the party.
Dry January — a modern trend that challenges people to abstain from drinking for the first month of the year — has become a popular way to “detox” from the holidays and start the new year on a healthy note.
Research has linked alcohol to a variety of health conditions, ranging from hangovers to higher cancer risk.
5 POPULAR HANGOVER MYTHS THAT DON’T WORK AFTER HOLIDAY DRINKING, ACCORDING TO EXPERTS
In a recent podcast episode of “The Dr. Mark Hyman Show,” Dr. Mark Hyman, chief medical officer of Function Health, shared how 30 days of not drinking alcohol can transform health.
Hyman, who is based in Massachusetts, called Dry January a “powerful way to see in real time how alcohol affects nearly every system of your body and how quickly those systems can recover.”
Dry January has become a popular way to “detox” from the holidays and start the new year on a healthy note. (iStock)
Alcohol’s toll on the brain and body
Hyman acknowledged that most people drink to feel happier and more comfortable in social situations. This effect is caused by the main ingredient in alcohol, called ethanol, which can also have toxic effects.
Instead of stimulating the brain, alcohol slows it down and loosens inhibitions. “You feel more relaxed, more social, more confident, maybe you feel a little euphoric,” Hyman said.
Alcohol’s effect on the brain can also lead to poorer decisions and slower reflexes, the doctor cautioned.
Drinking alcohol can cause cognitive decline and brain fog, experts warn. (iStock)
Drinking also impacts the prefrontal cortex of the brain, which Hyman described as “the adult in the room,” responsible for judgment, planning and restraint. “It goes offline early in drinking, which explains why people feel freer or act impulsively when they drink,” he said.
Even moderate drinking can cause metabolic stress, inflammation, impaired detoxification and hormonal shifts, Hyman said, which can impact nearly every organ system in the body.
POPULAR WEIGHT-LOSS DRUGS COULD TAKE THE EDGE OFF YOUR ALCOHOL BUZZ, STUDY FINDS
Alcohol consumption has also been linked to an increased risk of cancer, metabolic dysfunction, gut microbiome disturbances and mitochondrial toxins.
It can also prevent the body from falling into REM sleep, which is the deep rest recovery period when the immune system cleans out the day’s toxins, according to Hyman.
Alcohol can impact deep rest and mental health, according to experts. (iStock)
Memory loss, cognitive decline, anxiety, sleep disruption, dementia and cardiovascular disease are all known risks of long-term alcohol use, as well as liver complications like fatty liver disease.
“Bottom line, alcohol taxes every major system in your body, especially your liver, your brain, your gut, your hormones,” Hyman said.
The effects of 30 days with no alcohol
The first week after your last drink, the body begins to detoxify and reset, according to Hyman. Blood sugar and cortisol stress hormones level out, and the liver begins to process a “backlog of toxins.” The body also re-hydrates and re-energizes.
The first 30 days with no alcohol allows the body to balance itself out. (iStock)
The second week, the gut and brain will begin to re-balance, as hormones like serotonin and dopamine stabilize, gut inflammation drops and the microbiome begins to heal. Cravings for sugar and alcohol will wane and mental clarity returns, the doctor said.
Week three is marked by further decreases in inflammation, fatty liver and blood pressure. This can be noticeable in the skin, as puffiness and redness are reduced. Mood also begins to stabilize, with lower anxiety levels.
DOCTORS REVEAL WHY ALCOHOL CAUSES ‘BOOZE BUTT’ AND HOW TO PREVENT IT ON NEW YEAR’S
In week four, the body experiences additional metabolic and immune benefits, Hyman shared, including more insulin sensitivity, which makes it easier to lose weight.
“You have a stronger immune response. You’re not getting sick as much. You have better deep sleep, balanced hormones, especially cortisol and testosterone,” he said. “And you see a big change in energy, confidence and focus.”
Abstaining from alcohol can help restore energy, according to experts. (iStock)
Dr. Pinchieh Chiang, a clinician at Circle Medical in San Francisco, said that Dry January isn’t a “detox,” but rather provides “feedback” from the body.
“It gives the body time to show people how it feels without alcohol. For many, that insight alone changes their relationship with drinking,” she said. “The biggest surprise isn’t what people give up, it’s how much better they feel.”
HIGHER STROKE RISK LINKED TO CONSUMING CERTAIN AMOUNT OF ALCOHOL, STUDY FINDS
The doctor confirmed that the first few days of not drinking may feel harder than expected, sometimes causing restlessness, cravings or disrupted sleep, but Dry January can ultimately change drinking habits for the remainder of the year.
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
After a full year without alcohol, Chiang noted that health improvements are more profound. “We see sustained improvements in blood pressure, liver function and inflammation,” she said. “Those changes directly affect long-term heart disease and stroke risk.”
The risks of ‘all or nothing’
Some experts warn that adopting the Dry January trend could strengthen the urge to drink more in the other months, noting that some drinkers may find more success by slowly consuming fewer drinks per week.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
Thomas Stopka, Ph.D., an epidemiologist and professor in the public health and community medicine department at Tufts University School of Medicine in Massachusetts, shared in a Futurity report that for some people, “damp January” may be more suitable.
One expert warned that not all drinkers should quit “cold turkey,” as it could lead to severe withdrawals. (iStock)
“Dry January is well-intentioned, and it may work really well for the people who can stick to it, maybe even beyond January,” he said. “Other people may be more inclined to cut down on alcohol consumption rather than quit drinking completely for the month.”
CLICK HERE FOR MORE HEALTH STORIES
Stopka noted that successful harm-reduction approaches “aim to be judgment free.”
“Substance use disorder is a disease,” he said. “It takes time to treat the disease and to stay connected to the continuum of care — from prevention to treatment initiation to sustained therapy, whether through medication, self-help, or individual therapy or group support.”
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
Those struggling with signs of alcohol use disorder should consult a medical professional for personalized guidance.
Fox News Digital reached out to several alcohol industry associations requesting comment.
Health
The Best Weight Loss Medications and Supplements in 2026
Use left and right arrow keys to navigate between menu items.
Use escape to exit the menu.
Sign Up
Create a free account to access exclusive content, play games, solve puzzles, test your pop-culture knowledge and receive special offers.
Already have an account? Login
-
Detroit, MI7 days ago2 hospitalized after shooting on Lodge Freeway in Detroit
-
Technology4 days agoPower bank feature creep is out of control
-
Dallas, TX5 days agoDefensive coordinator candidates who could improve Cowboys’ brutal secondary in 2026
-
Dallas, TX2 days agoAnti-ICE protest outside Dallas City Hall follows deadly shooting in Minneapolis
-
Iowa4 days agoPat McAfee praises Audi Crooks, plays hype song for Iowa State star
-
Delaware1 day agoMERR responds to dead humpback whale washed up near Bethany Beach
-
Health6 days agoViral New Year reset routine is helping people adopt healthier habits
-
Nebraska4 days agoOregon State LB transfer Dexter Foster commits to Nebraska