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Seniors taking multiple medications may face unexpected health effects

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Seniors taking multiple medications may face unexpected health effects

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Older adults discharged from hospitals on multiple medications are less likely to regain independence during rehabilitation, a new study suggests.

The Japanese study, published in the journal BMC Geriatrics Dec. 17, explored the effects of polypharmacy — defined as taking six or more regular medications on a regular basis — at a convalescent rehabilitation hospital in Japan.

The retrospective observational study looked at 1,903 patients 65 and older who underwent rehabilitation at the hospital from April 2017 to March 2024, according to a press release.

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The patients had one of three conditions: cerebrovascular disease (a disorder of the brain’s blood vessels that reduce or block blood flow), motor disorder (a condition that affects movement and muscle control) or disuse syndrome (inactivity leading to muscle weakness and physical decline).

Of the total group, 62.1% of the patients were taking six or more medications when they were discharged from the hospital, and more than 76% of them were 80 or older. 

Older adults discharged from the hospital on multiple medications are less likely to regain independence during rehabilitation, a new study suggests. (iStock)

Those taking multiple medications were also more likely to be taking benzodiazepine receptor agonists (taken for anxiety or insomnia), laxatives and psychotropic medications (mainly used for depression, anxiety, psychosis and other mood disorders). 

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The researchers determined that those with polypharmacy who had cerebrovascular disease and disuse syndrome scored significantly lower in the functional independence measure (FIM), which assesses how independently a person can perform everyday activities, especially after illness, injury or hospitalization. Those in the motor disorder group didn’t show any link between polypharmacy and FIM.

The negative effects were stronger among adults over 80 and those recovering from stroke-related conditions or general weakness due to inactivity.

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Based on these findings, the researchers suggest that reviewing and reducing unnecessary medications could help improve recovery for those undergoing rehabilitation.

Dr. Marc Siegel, Fox News senior medical analyst, refers to polypharmacy with seniors as a “risky proposition.”

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The retrospective observational study looked at 1,903 patients 65 and older who underwent rehabilitation at a hospital from April 2017 to March 2024. (iStock)

“Even though each medication may have a purpose, often important, we must keep in mind that the ability to tolerate various medications and metabolize them efficiently diminishes as you get older,” he told Fox News Digital.

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“For example, a med that sedates you or even has the potential to disorient you may be more likely to do so as you become elderly.”

Drug interactions also tend to increase as patients grow older, Siegel added. 

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“This must all be monitored carefully by your physician, and, sometimes, less is more,” he said.

Based on these findings, the researchers suggest that reviewing and reducing unnecessary medications could help improve recovery for those undergoing rehabilitation. (iStock)

The study did have some limitations, the researchers acknowledged. Due to its retrospective and observational design, it does not prove that the medications caused the outcome.

The researchers also lacked data on specific doses of the medications and the intensity of the rehabilitation, they noted. Also, the study was conducted at just a single hospital, so the results may not apply to more general populations.

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Future research is needed to determine which specific medications most affect recovery and to explore the best approaches for reducing prescriptions.

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Diabetes surge among Americans could be driven by ‘healthy’ breakfasts, doctor warns

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Diabetes surge among Americans could be driven by ‘healthy’ breakfasts, doctor warns

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Americans consume foods every day that are marketed as “healthy,” when they could be quietly destroying their health, one doctor warns.

Dr. Mark Hyman, physician and co-founder of Function Health in California, says that much of America’s daily diet is filled with unhealthy ingredients.

“The amount of refined starches and sugars that are everywhere is just staggering to me, given what we know about how harmful they are,” he shared in an interview with Fox News Digital. “I don’t think people really understand.”

Hyman, author of the new book “Food Fix Uncensored,” said he’s “astounded” by what people are eating, especially for breakfast.

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“People just eat sugar for breakfast,” he said. “They have muffins, they have bagels, they have croissants, they have sugar-sweetened coffees and teas.”

Dr. Mark Hyman is the author of the new book “Food Fix Uncensored.” (Function Health; Little, Brown Spark)

In addition to the traditionally sweet options for breakfast, some cereal brands and breakfast staples have adopted new “protein-packed” menu items and products, following health trends that encourage eating more protein.

“Highly processed food is not food.”

“Now, we’re seeing this halo of protein in certain things,” Hyman said, mentioning that many protein smoothies are “full of sugar.”

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The doctor also noted that some popular cereals are now marketed as having protein in them. “My joke is, if it has a health claim on the label, it’s definitely bad for you,” he said.

Instead of starting the day with a “quick fix” or processed food, Hyman suggests choosing whole sources of protein and fat for breakfast, adding that “if there’s a little carbohydrate in there, it’s fine.”

More products marketed as “high protein” have cropped up on supermarket shelves. (iStock)

For his own breakfast, Hyman said he has a protein shake with whey protein, avocado and frozen berries. Eggs and avocados are also a great protein-and-fat combo option, he added.

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“It’s not that complicated — people need to just think about their breakfast not being dessert,” he said. “No wonder we’re in this cycle of obesity and diabetes. One in three teenage kids now has type 2 diabetes or pre-diabetes. That’s just criminal.”

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Instead of counting calories and being in a caloric deficit as a way to lose weight and stay healthy, Hyman instead suggests focusing on how certain foods make you feel and how they impact your health.

“When you look at the way in which different types of calories affect your biology, you can just choose what you’re eating, and then you don’t have to worry about how much,” he told Fox News Digital.

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In addition to the traditionally sweet options for breakfast, some cereal brands and breakfast staples have adopted new “protein-packed” menu items and products. (iStock)

“For example, if you eat a diet that doesn’t cause your insulin to spike — which is low in starch and sugar, higher in protein and fat — you won’t develop those swings in blood sugar, you won’t develop the spikes in insulin, you won’t deposit hungry fat … You will break that cycle.”

People are more likely to “self-regulate when they eat real food” instead of processed foods, which “bypasses the normal mechanisms of satiety, fullness and brain chemistry,” according to Hyman.

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“Ultraprocessed food and junk food or highly processed food is not food,” he said. “It doesn’t support the health and well-being of an organism. It doesn’t do that. It does the opposite.”

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Scientists make startling discovery when examining prostate cancer tissue

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Scientists make startling discovery when examining prostate cancer tissue

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Small fragments of plastic were found in the tumors of most prostate cancer patients, according to a new study from NYU Langone Health. 

In past studies, microplastics have been found in almost every human organ and in bodily fluids, but their impact on human health still isn’t fully understood.

The researchers analyzed tissue samples from 10 patients with prostate cancer who underwent surgery to remove the entire organ. 

Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples, according to the study press release.

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In past studies, microplastics were found in almost every single human organ along with bodily fluids, even the placenta. (iStock)

The cancerous tissue contained on average more than double the amount of plastic as healthy prostate tissue samples, the study found. This equates to about 40 micrograms of plastic per gram of tissue compared to 16 micrograms.

Researchers avoided contaminating the samples with other plastics by substituting standard tools with those made of aluminum, cotton and other non-plastic material, the release noted.

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The scientists say this is the first direct evidence linking microplastics to prostate cancer.

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“By uncovering yet another potential health concern posed by plastic, our findings highlight the need for stricter regulatory measures to limit the public’s exposure to these substances, which are everywhere in the environment,” said senior study author Vittorio Albergamo, assistant professor in the department of pediatrics at NYU Grossman School of Medicine, in the release.

Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples. (iStock)

The study findings were presented during the American Society of Clinical Oncology’s Genitourinary Cancers Symposium in San Francisco on Feb. 26.

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“What is most striking is not that microplastics were detected, but that they were found embedded within tumor tissue itself,” Dr. David Sidransky, oncologist and medical advisor at SpotitEarly, a startup that offers an at-home breath-based test to detect early-stage cancer, told Fox News Digital.

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“While complete avoidance is unrealistic, people can take practical steps to reduce exposure.”

“We already know microplastics are present in water, air, blood and even placental tissue. Their detection in prostate tumors suggests systemic distribution and long-term bioaccumulation,” added Maryland-based Sidransky, who was not involved in the study.

Study limitations

Albergamo cautioned that a larger sample is needed to confirm the findings. Additionally, Sidransky noted that the presence of microplastics alone does not prove they cause cancer.

“Tumors can act as ‘biologic sinks,’ meaning they may accumulate circulating particles simply because of altered vasculature and permeability,” he said.

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A key unanswered question, according to the doctor, is whether microplastics are biologically active in ways that “promote DNA damage, immune modulation or chronic inflammation within the prostate.”

About one in eight men in the U.S. will be diagnosed with prostate cancer at some point in their lifetime, according to the Centers for Disease Control and Prevention.

The most actionable step men can take is appropriate screening and early detection, according to doctors. (iStock)

For those concerned about microplastics, Sidransky offered some insights.

“I believe the appropriate response is curiosity, not panic, and a commitment to understand more,” he said.

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“While complete avoidance is unrealistic, people can take practical steps to reduce exposure, such as minimizing heating food in plastic containers, reducing bottled water consumption when possible, and favoring glass or stainless steel alternatives.”

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The most actionable step men can take, however, is getting appropriate screenings to help ensure early detection, according to the doctor. Screening discussions should be individualized based on age, family history and other risk factors.

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How a Vegan Diet Can Help You Lose Weight 8X Faster

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How a Vegan Diet Can Help You Lose Weight 8X Faster


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How a Vegan Diet Helps You Lose Weight 8X Faster | Woman’s World




















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