A vaccine created using artificial intelligence that could potentially provide broader protection against multiple coronaviruses and help prepare for future outbreaks has passed its first human clinical trial.

Researchers from the Universities of Cambridge and Southampton developed a “universal vaccine” designed to protect against multiple Sarbeco coronaviruses, which the university explained in a news release is “the large group of viruses that occur in nature, including SARS-CoV-2, which caused the COVID pandemic.”

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Traditional vaccines must constantly be updated as viruses mutate, and the process is “like a dog chasing its tail,” said University of Southampton professor Saul Faust, the trial’s chief investigator.

“Viruses like Influenza, coronaviruses and the Ebola group are evolving continuously, and by the time vaccines are rolled out, they may be poorly matched — the current ‘reactive’ vaccine system struggles to keep pace,” Faust said.

An antigen is the active ingredient in a vaccine meant to trigger an immune-system response and fight off infection. According to the release, the university scientists logged all the available genetic sequence data for Sarbeco coronaviruses and used AI used to design a “super-antigen” that contains the antigen features “common to this whole group of viruses – including ones that haven’t emerged yet.”

The trial of the vaccine proved safe and triggered an immune response in 39 healthy volunteers, marking “the first time that a vaccine whose active component was designed entirely by computer simulations has been tested in humans,” the release said.

The trial vaccine was administered through a micro-fluid jet that delivers the immunization through the skin using a tiny, high-pressure stream of liquid and does not require a needle. The researchers said this method could make it “faster and easier to carry out in large numbers of people.”

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“This new class of universal vaccines are future-proofed,” Faust said. “They not only protect against many variants simultaneously, but potentially against related viruses that haven’t yet emerged and spilt over to humans. If we can develop and clinically advance this new class of vaccines before a virus outbreak begins, millions of lives could be saved, lockdowns avoided and the economy preserved.”

Some experts have raised broad concerns about using AI in medicine, primarily when it comes to making clinical decisions, not developing vaccines. Certain groups of people may be underrepresented in the data AI relies on, resulting in biased outcomes, some said.

AI also sometimes produces erroneous information, called “hallucinations,” and determining who is liable for medical failings in such situations is a complex matter.

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Others have expressed concern over patient privacy, as well as the need for human judgment that takes into account the scope of a patient’s health history, rather than a single dataset.

The universal-vaccine researchers said that a larger trial involving “a wider and more diverse population” is needed. They published their findings in Journal of Infection.

Former professional wrestler and actor Tyler Mane announced he has been diagnosed with breast cancer.

Known for his roles in “X-Men” and “Halloween,” Mane shared the news publicly to help raise awareness about a condition that is frequently overlooked in men.

“I have some bad news. I start chemo today,” Mane stated in a video posted to his social media channels. “One in 750 men will be diagnosed with breast cancer in their lifetime, and I’m one of them.”

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Because breast cancer is predominantly associated with women, many men are unaware that they are also at risk. However, according to Mayo Clinic, everyone is born with a small amount of breast tissue.

While women go on to develop more of this tissue during puberty, the biological foundation for the disease exists in everyone.

The most common symptom of male breast cancer is a hard, painless lump located directly behind or near the nipple, according to experts. Other signs can include skin dimpling, nipple retraction or discharge.

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Male breast cancer is rare, accounting for less than 1% of all cases globally. Because routine screenings like mammograms are not standard practice for men, the disease is often caught much later than it is in women.

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Mane highlighted this issue as a primary motivation for speaking out. “Because it’s rarely talked about, it’s usually found at later stages and has worse outcomes,” he said. “I want to change that.”

Medical data supports Mane’s concerns regarding late-stage detection. While male breast cancer can occur at any age, it is most frequently diagnosed in older men, according to Mayo Clinic.

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Men’s treatment plans generally mirror those for women, typically involving surgery to remove the breast tissue, followed by chemotherapy, radiation or hormone therapy depending on how far the cancer has progressed.

Mane said he is utilizing his platform to normalize conversations about male health and encourage early detection. He concluded his video by asking his followers to spread the word and help educate others.

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“Follow, like and share, and come along for my journey to kick this thing in the ass,” Mane said. “Send this to 10 of your friends and have them follow me, because people need to hear this.”

Veteran New York news anchor Bill Ritter revealed Friday that he has been diagnosed with early-stage Alzheimer’s disease, bringing an end to his more than two-decade run behind the WABC-TV anchor desk.

Ritter, 76, who has anchored the station’s 6 p.m. newscast in New York City since 2001, revealed during Friday’s Eyewitness News broadcast that it would be his final night anchoring the program.

“After a series of tests, my doctors have told me I have Alzheimer’s,” Ritter said during the broadcast.

“It’s early-stage Alzheimer’s, and they say the treatments I’m getting are keeping it at bay, for now,” he continued. “But there is no guarantee, because there’s no cure yet for Alzheimer’s.”

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“So, unless someone finds an amazing cure, and soon, tonight will be the last newscast I anchor,” he added.

According to ABC7, Ritter joined WABC-TV in 1998 after an extensive journalism career that included work at the Los Angeles Times, local television stations in California and positions with ABC News.

He began anchoring the station’s 11 p.m. Eyewitness News broadcast in 1999 and was added to the flagship 6 p.m. newscast in 2001. He also anchored the station’s 5 p.m. broadcast for several years.

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ABC7 reported that Ritter will remain with the station in a new role focused in part on reporting about Alzheimer’s disease and other neurological conditions, as well as their impact on patients and families.

“For decades, Bill Ritter has covered and led New Yorkers through the stories that matter most,” WABC-TV General Manager Marilu Galvez said in a statement.

“A defining presence at ABC7, he has done so with exceptional insight, integrity and, most of all, heart, earning the love and respect of viewers and colleagues alike,” she continued.

“While he is stepping away from daily anchoring, he will continue to be an integral part of our ABC7 family, including sharing personal updates and providing resources to help others impacted by Alzheimer’s better understand the disease and the resources available to them.”

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“Bill is strong, brilliant, and resourceful, and we look forward to his continued reporting on Eyewitness News,” Galvez added.

New York City Mayor Zohran Mamdani responded to Ritter’s announcement by wishing the veteran broadcaster and his family “strength in the days ahead.”

“For decades, Bill Ritter has been a trusted presence in New Yorkers’ homes, helping us make sense of the news that shape our city,” Mamdani wrote on X. “

“His courage in sharing his Alzheimer’s diagnosis will help countless families facing the same challenge feel less alone,” he continued. “Wishing Bill, his loved ones, and everyone affected by Alzheimer’s strength in the days ahead.”

Ritter’s colleagues also reacted to his announcement.

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WABC-TV reporter Lucy Yang paid tribute to Ritter’s professionalism and dedication during his decades-long career at the station.

“For decades, I’ve reported for his show and even filled in, anchored w him,” she posted on X. “He never gave less than 110% I salute you. I thank you. And I will pray for you.”

Lee Goldberg, the station’s chief meteorologist, said Ritter’s influence would continue long after he stepped away from the anchor desk.

“He preaches be kind, take care of each other, & we’re all in this together,” Goldberg said on X. “Now, in addition to doing these things for himself & his loving family, he’ll build on his legendary legacy by helping millions who share his battle.” 

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“You’re a saint, and my hero @billritter7,” he added. “Love you.”

Ritter also noted during the broadcast that his father died from Alzheimer’s disease in 1998 after battling the illness for years.