Health
Sepsis a top killer in US behind heart disease, cancer: What to know, how to avoid the condition
“Real Housewives of Orange County” star Vicki Gunvalson, 62, is sharing her recent health scare after she was hospitalized with sepsis, a potentially deadly disease that results from the body’s response to an infection.
“This entire health scare came unannounced — with no warning,” Gunvalson told Fox News Digital.
As Sepsis Awareness Month kicks off this September, Gunvalson’s timely story is helping to raise awareness of the illness.
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“Sepsis awareness can and does save lives, yet only 65% of American adults have ever heard of it,” Selena A. Gilles, clinical professor and associate dean at New York University Rory Meyers College of Nursing, told Fox News Digital.
Gilles is on the advisory board of the Sepsis Alliance, a California-based organization that works across the country to decrease suffering from sepsis.
Sepsis kills 350,000 American adults each year and is a leading cause of death in U.S. hospitals, statistics show. (iStock)
“Prompt recognition and treatment can be of great importance in preventing significant illness and even mortality,” Dr. Aaron Glatt, chief of infectious diseases at Mount Sinai South Nassau Hospital on Long Island, New York, told Fox News Digital.
Gunvalson’s diagnosis
Gunvalson shared the details of her sepsis diagnosis with Fox News Digital.
“Two weeks ago, when I was heading to my office, I was very delirious and unclear on where I was going,” Gunvalson said via email.
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“Once I got into the office, my staff realized I was not acting normal,” she went on. “My assistant thought that I was possibly having a stroke.”
The emergency room diagnosed Gunvalson with a “sinus disease” and sent her home, but by the next morning, she was “extremely incoherent” — so her boyfriend took her back to the hospital.
“Real Housewives of Orange County” star Vicki Gunvalson, 62, is sharing her recent health scare after she was hospitalized with sepsis, a potentially deadly disease that results from the body’s response to an infection. (Amanda Edwards/Getty Images)
“I was admitted for six days with sepsis and pneumonia,” she said.
Gunvalson was treated with a course of antibiotics and is now recovering at home, while staying in regular contact with the sepsis team at the hospital.
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The reality TV star has experienced some memory loss and difficulty concentrating, but said she hopes the “brain fog” will improve over time.
In retrospect, the sepsis may have stemmed from a sinus infection two months ago that was treated by multiple rounds of antibiotics, Gunvalson said.
Symptoms and dangers
Common symptoms of sepsis include fever, chills, rapid heart rate, confusion, shortness of breath, extreme pain, and clammy or sweaty skin, according to Gilles.
A high fever – especially in those who are at increased risk of infection and are feeling extremely unwell – should warrant seeking medical attention as soon as possible, Glatt added.
“Sepsis awareness can and does save lives, yet only 65% of American adults have ever heard of it.”
“Fatigue and lethargy in the setting of infection can be a sign of pneumonia and potential sepsis, even without overt pulmonary symptoms,” Dr. Marc Siegel, Fox News’ senior medical analyst and clinical professor of medicine at NYU Langone Medical Center, told Fox News Digital.
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As sepsis can start within hours, Gilles suggested following the acronym “TIME” to remember that time is of the essence when it comes to seeking treatment.
T – Temperature (higher or lower than normal)
I – Infection (know the signs and symptoms)
M – Mental decline (confusion, sleepiness and difficulty awakening)
E – Extremely ill (severe pain, discomfort and shortness of breath)
Approximately 1.7 million adults are diagnosed with sepsis every year in the U.S., according to the Centers for Disease Control and Prevention (CDC).
Approximately 1.7 million adults are diagnosed with sepsis every year in the U.S., according to the Centers for Disease Control and Prevention. (iStock)
The illness kills 350,000 American adults each year and is a leading cause of death in U.S. hospitals, Gilles noted.
It is the third-leading killer behind heart disease, which takes just over 700,000 lives each year, and cancer, which causes more than 600,000 annual deaths, per CDC data.
“Sepsis takes a life every 90 seconds — that’s more lives than opioids, breast cancer, prostate cancer and stroke combined,” she said.
Common myths about sepsis
Many people mistakenly assume that sepsis is an infection.
“Sepsis is the body’s overwhelming and life-threatening response to infection, which can lead to tissue damage, organ failure and death,” Gilles said.
The condition can come after any infection — whether just a scrape or cut, a dental procedure or surgery, or even a [bacteria], fungus or parasite — triggers a “chain reaction” in the body, the doctor added.
Treatment of sepsis will vary based on the underlying infection, but it often involves administering antibiotics as soon as possible. (iStock)
Another common myth is that sepsis only occurs in those who are (or were recently) hospitalized.
Most cases of sepsis, around 87%, start before a patient enters the hospital, Gilles said.
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“Community-acquired infections, such as urinary tract infections, pneumonia and even simple cuts or scrapes can lead to sepsis if not treated properly,” Gilles noted.
Many people also think sepsis only affects immunocompromised people.
Older adults, infants and those with chronic illnesses or weakened immune systems are at a higher risk of sepsis. (iStock)
“Sepsis can strike almost anyone at almost any time,” Glatt said.
“While certain individuals are at higher risk of getting a severe infection that can even be deadly, serious infections can strike even a perfectly healthy young person with rare but potentially fatal consequences,” he went on.
Older adults, infants and those with chronic illnesses or weakened immune systems are at a higher risk, however.
Treatment and prevention
The first step is discovering the underlying cause of the infection, according to the CDC.
Sepsis often starts in the gastrointestinal tract, lungs, skin or urinary tract.
“Sepsis is the body’s overwhelming and life-threatening response to infection, which can lead to tissue damage, organ failure and death,” a doctor said. (iStock)
Treatment will vary based on the underlying infection, but often involves administering antibiotics as soon as possible.
“While antibiotics are crucial for treating an underlying bacterial infection, managing sepsis often requires a comprehensive approach — including fluids, medications to support blood pressure, and sometimes surgery or [a ventilator], depending on the severity,” said Gilles.
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Surgery is sometimes necessary to remove tissue damaged by the infection, the CDC states.
It’s also important to maintain blood flow to the organs, often with fluids.
“Sepsis can strike almost anyone at almost any time.”
“If you suspect sepsis, seek medical attention right away,” Gilles advised.
The risk can be reduced by quickly identifying and managing infections, according to the doctor.
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Added Gilles, “It can also be prevented by practicing good hygiene, staying current with vaccinations, staying in good health, keeping cuts clean and dry, and promptly seeking treatment when infections are suspected.”
Health
Matt Damon’s Gluten-Free Diet Helped Him Lose 18 Pounds
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Health
Deadly cancer risk could drop with single 10-minute workout, study suggests
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A single 10-minute workout may trigger blood changes that help fight colon cancer.
That’s according to new research from scientists at Newcastle University, who found that exercise quickly changes the blood in ways that affect colon cancer cells in the lab.
In the study, the U.K. researchers exposed colon cancer cells to human blood serum collected immediately after exercise, finding that the cells repaired DNA damage faster and showed gene activity patterns linked to slower growth.
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The blood samples came from 30 adults who had just completed a short, high-intensity cycling workout that lasted about 10 to 12 minutes, according to a press release.
Even a 10-minute burst of intense exercise may send protective signals through the blood that affect colon cancer cells, researchers say. (iStock)
Samuel T. Orange, an associate professor at Newcastle University and one of the study’s authors, spoke with Fox News Digital about the findings.
“Our findings show that exercise rapidly triggers molecular changes in the bloodstream that can act directly on colon cancer cells, reshaping gene activity and supporting DNA damage repair,” he said.
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The results suggest that even brief activity can make a difference. “Every movement matters. Exercise doesn’t need to last hours or happen in a gym,” Orange added.
The research suggests that exercise quickly triggers changes in the blood that affect colon cancer cells and helps support DNA repair. (iStock)
One of the most surprising findings, according to the researcher, was how strong the biological response was after even a single workout.
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“Exercise altered the activity of more than 1,000 genes in colon cancer cells,” he shared.
Even brief bouts of activity can make a difference, the researcher said. (iStock)
The study findings suggest that the effect is driven by exercise-triggered molecules released into the bloodstream, sometimes referred to as “exerkines,” which act like chemical messengers and send signals throughout the body.
“Each time you exercise, you trigger biological signals that support health and resilience to diseases such as cancer, diabetes and heart disease,” Orange said.
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The researchers cautioned that the study was conducted using cancer cells grown in the laboratory, not in patients.
The findings are based on experiments using colon cancer cells grown in the lab, not studies conducted in people, the researchers noted. (iStock)
The study involved 30 healthy male and female volunteers between the ages of 50 and 78. Their blood samples were used to carry exercise-triggered signals to cancer cells grown in the lab.
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“These findings now need to be replicated in people with cancer,” Orange said. “We also need to better understand the longer-term effects of repeated exercise signals over time.”
Despite the limitations, the researcher said the findings strengthen the case for exercise as an important part of colon cancer prevention.
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“Each time you move your body and get a little breathless, you’re contributing to better health and may help influence biological processes linked to bowel cancer,” he added.
Health
Brain Health Challenge: Try a Brain Teaser
Welcome back! For Day 4 of the challenge, let’s do a short and fun activity based around a concept called cognitive reserve.
Decades of research show that people who have more years of education, more cognitively demanding jobs or more mentally stimulating hobbies all tend to have a reduced risk of cognitive impairment as they get older.
Experts think this is partly thanks to cognitive reserve: Basically, the more brain power you’ve built up over the years, the more you can stand to lose before you experience impairment. Researchers still don’t agree on how to measure cognitive reserve, but one theory is that better connections between different brain regions corresponds with more cognitive reserve.
To build up these connections, you need to stimulate your brain, said Dr. Joel Salinas, a neurologist at NYU Langone Health and the founder and chief medical officer of the telehealth platform Isaac Health. To do that, try an activity that is “challenging enough that it requires some effort but not so challenging that you don’t want to do it anymore,” he said.
Speaking a second language has been shown to be good for cognition, as has playing a musical instrument, visiting a museum and doing handicrafts like knitting or quilting. Reading is considered a mentally stimulating hobby, and experts say you’ll get an even bigger benefit if you join a book club to make it social. Listen to a podcast to learn something new, or, better yet, attend a lecture in person at a local college or community center, said Dr. Zaldy Tan, the director of the Memory and Healthy Aging Program at Cedars-Sinai. That adds a social component, plus the extra challenge of having to navigate your way there, he said.
A few studies have found that playing board games like chess can be good for your brain; the same goes for doing crossword puzzles. It’s possible that other types of puzzles, like those you find in brain teaser books or from New York Times Games, can also offer a cognitive benefit.
But there’s a catch: To get the best brain workout, the activity should not only be challenging but also new. If you do “Wordle every day, it’s like well, then you’re very, very good at Wordle, and the Wordle part of your brain has grown to be fantastic,” said Dr. Linda Selwa, a clinical professor of neurology at the University of Michigan Medical School. “But the rest of your mind might still need work.”
So play a game you’re not used to playing, Dr. Selwa said. “The novelty seems to be what’s driving brain remodeling and growth.”
Today, we want you to push yourself out of your cognitive comfort zone. Check out an online lecture or visit a museum with your challenge partner. Or try your hand at a new game, below. Share what novel thing you did today in the comments, and I’ll see you tomorrow for Day 5.
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