World
Use of Wegovy and other weight-loss drugs soars among kids and young adults
At 17, Israel McKenzie was so burdened by obesity that he stopped going to high school in person and was embarrassed to speak to people at his restaurant job.
“I was in a really dark place,” says McKenzie, whose weight had climbed to 335 pounds on his 6-foot-1 frame, despite repeated efforts to diet and exercise. “I had given up hope.”
But last year, the weight-loss drug Wegovy helped him shed 110 pounds in nine months, making the rural Tennessee teen part of a surge of adolescents and young adults using diabetes and obesity medications known as GLP-1 receptor agonists, new research shows.
Even as millions of older adults clamor for drugs such as Ozempic and Wegovy, monthly use of the medications soared in people aged 12 to 25. That’s according to the new analysis of dispensing records from nearly 94% of U.S. retail pharmacies from 2020 to 2023.
The report, published in the journal JAMA on Wednesday, used the IQVIA prescription database to compile the first look at the national uptake of GLP-1 drugs among that age group. Nearly 31,000 children aged 12 to 17 and more than 162,000 people aged 18 to 25 used the medications in 2023 alone, said Dr. Joyce Lee, a University of Michigan pediatrician and diabetes expert who led the research.
“What it’s suggesting is that it’s one of the tools in the toolbox and there are more providers prescribing this medication for the population,” she said.
The report shows that the number of 12- to 25-year-olds using any GLP-1 drug — including older medications first approved to treat diabetes in 2005 and for weight loss in 2014 — climbed from about 8,700 a month in 2020 to more than 60,000 a month in 2023, a nearly 600% increase. The rise occurred even as prescriptions of other drugs among those patients fell by about 3%.
Those who received the drugs were just a fraction of young people who struggle with obesity, Lee noted. About 20% of U.S. children and adolescents and about 42% of adults have the chronic disease, according to the U.S. Centers for Disease Control and Prevention.
In early 2023, the American Academy of Pediatrics recommended that children and teens with obesity be evaluated early and treated aggressively, including with surgery and medication if warranted.
McKenzie, the Tennessee teen, said he began gaining weight five years ago, during puberty.
“I started turning to food for all of my problems,” he said.
The extra weight made his asthma worse and put him in danger of developing diabetes, his doctor said. He tried to follow medical advice by cutting out sugary soda and snack foods and exercising more, but the efforts failed to make a difference.
“My old doctor told me there was nothing he could do,” he said. “He told me it was my fault.”
In early 2023, McKenzie connected with Dr. Joani Jack, a pediatric obesity specialist at Children’s Hospital at Erlanger in Chattanooga, Tennessee, who regularly prescribes GLP-1 drugs for kids.
“I told him I’ve seen 10 other people just like you today and we have lots of tools and treatment options,” Jack said. Those typically include intensive behavioral and nutrition interventions combined with medication, if necessary.
In McKenzie’s case, Jack prescribed the weight-loss drug Wegovy, which in late 2022 was approved for use in U.S. children over age 12. More than 6,000 kids in that age group received Wegovy in 2023, the new data show. More than 7,600 received Ozempic, which is approved to treat diabetes in adults, but can be used off-label in adolescents. Others received older GLP-1 drugs such as Saxenda and Trulicity.
McKenzie said he had no notable side effects from the medication, but Lee noted that some young people report nausea, vomiting or constipation, including symptoms so serious that they stop the drugs.
It’s important to understand the surging use of these medications in young people, Lee said. The drugs are meant for continuing use, so “we really need to think about the long-term safety and effectiveness of these medications for this population,” she said.
In addition, the drugs are expensive and often difficult to obtain, either because of supply problems or because they’re not covered by insurance.
Notably, government-run Medicaid plans paid for nearly half of the GLP-1 drugs prescribed to 12- to 17-year-olds and about a quarter of those used by people aged 18 to 25, the research found. Commercial insurance covered care for nearly 44% of the younger kids and about two-thirds of those who were older.
Today, McKenzie says his asthma is better and he looks forward to interacting with co-workers and friends.
“I have a lot of self-confidence now, a lot more than I used to,” he said. “It has changed everything.”
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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.
World
Intense Israeli strikes hit Iran and Lebanon as US warns the bombardment will ‘surge dramatically’
DUBAI, United Arab Emirates (AP) — Intense Israeli airstrikes pounded the capitals of Iran and Lebanon early Friday as the U.S. apparently struck an Iranian drone carrier at sea in its unrelenting campaign against the Islamic Republic’s fleet of warships.
Iran launched new retaliatory attacks in the Middle East at the end of a full week of bombardment, which U.S. Defense Secretary Pete Hegseth warned was “about to surge dramatically.”
Israel’s military said Friday morning it had begun “a broad-scale wave of strikes” on Tehran, Iran’s capital. Witnesses described the Israeli airstrikes as particularly intense, shaking homes in the area. Others reported explosions around the Iranian city of Kermanshah in an area that is home to multiple missile bases.
The Israeli military said strikes have already destroyed most of Iran’s air defenses and missile launchers.
The war has escalated to affect countries across the Middle East and beyond. Early Friday, Iran fired missile and drone attacks into Kuwait, Qatar, Saudi Arabia and Bahrain, all countries that host U.S. forces. There were no immediate reports of casualties.
In Lebanon, where the war has rekindled fighting between Israel and Iran-allied Hezbollah militants, Israel launched a series of airstrikes late Thursday into Friday in the southern suburbs of Beirut and other areas. Motorists jammed roads trying to flee or seek shelter.
The U.S. and Israel have battered Iran with nationwide strikes, targeting their military capabilities, leadership and nuclear program.
In addition to Israel, Iran’s attacks have targeted their Arab neighbors, disrupted oil supplies and snarled global air travel. The war has killed at least 1,230 people in Iran, more than 120 in Lebanon and around a dozen in Israel, according to officials in those countries. Six U.S. troops have been killed.
US says it struck an Iranian drone carrier
The U.S. military said early Friday that it struck an Iranian drone carrier, setting it ablaze.
The U.S. military’s Central Command released black-and-white footage of the burning carrier. The Iranian military did not immediately acknowledge the attack.
The drone carrier, the IRIS Shahid Bagheri, is a converted container ship with a 180-meter-long (yard) runway for drones. The vessel can travel up to 22,000 nautical miles without needing to refuel in ports, reports said at the time of its 2025 inauguration.
Adm. Brad Cooper, head of U.S. Central Command, described the carrier as “roughly the size of a World War II aircraft carrier.”
“And as we speak, it’s on fire,” Cooper told reporters.
Earlier in the week, an American submarine sank an Iranian frigate off the coast of Sri Lanka as it was returning from an exercise hosted by the Indian navy that the U.S. also joined. The sinking killed at least 87 sailors.
Under cover of darkness Friday morning, B-2 stealth bombers dropped dozens of 2,000 pound “penetrator” bombs on deeply buried ballistic missile launchers inside Iran, Cooper said.
“We’ve also struck Iran’s equivalent of Space Command, which degrades their ability to threaten Americans,” Cooper said.
Speaking alongside Cooper, Hegseth gave few details when he promised an upcoming surge.
“It’s more fighter squadrons, it’s more capabilities, it’s more defensive capabilities,” Hegseth said. “And it’s more bomber pulses more frequently.”
Iran targets country’s hosting US forces
Qatar’s Defense Ministry reported early Friday it intercepted a drone attack targeting Al Udeid Air Base, which hosts the forward headquarters of the U.S. Central Command.
Saudi Arabia intercepted and destroyed three ballistic missiles fired early Friday toward Prince Sultan Air Base south of Riyadh, which hosts U.S. forces, said a spokesperson for Saudi Arabia’s Ministry of Defense.
Air raid sirens sounded in Bahrain, where the Interior Ministry said Iranian strikes targeted two hotels and a residential building. It said there were no casualties. In Kuwait, where the six U.S. soldiers were killed Sunday, the Kuwaiti army said its air defenses were activated when missile and drone attacks breached Kuwait’s airspace.
Cooper said Iranian attacks had now hit a dozen countries, who would be welcome to play a more active role in the conflict.
“Those 12 countries are none too happy and I look forward to working with all the partners who are willing to join us,” he said.
Trump again urges Iranians to “take back” their country
In brief remarks at the White House, U.S. President Donald Trump again urged the Iranian people to “help take back your country.” This time he promised the U.S. would grant them “immunity” amid the war and ongoing dangers under the current Iranian regime.
“So you’ll be perfectly safe with total immunity,” Trump said, without giving any details about what that meant. “Or you’ll face absolutely guaranteed death.”
Cooper and Hegseth cautioned Iranians not to take to the streets while the conflict is still raging, however.
“It’s common sense, don’t go out and protest while bombs are dropping” Hegseth said.
“The best thing for them to do now is just to lay low,” Cooper added.
In an interview with the news website Axios, Trump said he should be involved in choosing Iran’s new supreme leader to replace Ayatollah Ali Khamenei, who was killed in the opening strikes of the war. Trump spoke dismissively of Khamenei’s son, Mojtaba Khamenei, being a front-runner to replace his father, calling him “a lightweight.”
“We want someone that will bring harmony and peace to Iran,” Trump said.
Iranian officials meet to discuss new leadership
Iranian state television reported Friday that a leadership council had started discussing how to convene the country’s Assembly of Experts, which will select the new supreme leader.
The leadership council includes President Masoud Pezeshkian, judiciary chief Gholam Hossein Mohseni Ejehi and cleric Ayatollah Ali Reza Arafi.
The statement provided no timeline on the selection of the supreme leader, nor information on whether the Assembly of Experts would meet in person or remotely for the vote.
Buildings associated with the Assembly of Experts, a 88-member clerical panel, have been attacked during the Israeli-U.S. airstrike campaign.
Israel hits Lebanon with multiple airstrikes around Beirut
Israel carried out at least 11 airstrikes late Thursday and early Friday, targeting the southern suburbs of Beirut. Fires broke out near a gas station.
The Israeli army issued a warning Thursday evening, urging residents to “save your lives and evacuate your homes immediately.” Two hospitals evacuated patients and staff. No casualties were immediately reported.
The Lebanese health ministry said the death toll has risen to 123 since the resurgence of hostilities between Israel and Hezbollah, which struck Israel in the opening days of the war.
A spokesperson for the U.N. peacekeeping force in southern Lebanon, Tilak Pokharel, said Thursday that peacekeepers had seen and heard clashes, including ground combat, in southern Lebanon as more Israeli forces have moved across the border.
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Bynum reported from Savannah, Georgia, Rising from Bangkok and Abou AlJoud from Beirut, Lebanon. AP journalists around the world contributed.
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This version has corrected the date of the ship’s inauguration to 2025, not 2005.
World
Private flights account for 30% of departures from Oman airport as wealthy evacuate Middle East
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Long border crossings, SUV convoys and six-figure jet charters have become the new escape route out of the Middle East as Operation Epic Fury intensifies, with private flights now accounting for nearly a third of all departures from Oman’s main airport.
FlightRadar24, a real-time flight tracking platform, reported that while Oman continues to be a “vital” hub for evacuation and repatriation flights, private flights accounted for 31% of operations Wednesday at Muscat International Airport.
As of Thursday afternoon, the platform reported more than 30% of all movements at the airport were private flights.
Semafor reported earlier this week that airports in Oman and Saudi Arabia were drawing ultra-wealthy travelers looking to leave the countries.
Oman continues to be a “vital” hub for evacuation flights at its Muscat International Airport. (Christopher Pike/Bloomberg via Getty Images)
People familiar with the matter told the outlet that private security companies have been booking fleets of SUVs to take people on the 10-hour drive from Dubai to Riyadh, Saudi Arabia, where private flights are available.
The clientele evacuating the region are a mix of senior executives at global finance firms and wealthy travelers in the region for business or vacation, according to Semafor.
LIV golfer Jon Rahm, a two-time major winner, was just one of the wealthy who arranged flights amid the turmoil.
MIDDLE EAST CRUISE NIGHTMARE DEEPENS AS IRAN AIRSTRIKES LEAVE PASSENGERS STRANDED
Rahm arranged a charter flight through his partnership with VistaJet, a private aviation company, to fly the seven stranded LIV golfers and a caddie from Oman to Hong Kong after their flights were canceled.
After a more than four-hour drive to Oman, the crew flew to Hong Kong.
A spokesperson for Air Charter Service, a company that acts as a global broker for private jets and freight transport, told FOX Business the company has arranged more than 10 evacuation flights, with more scheduled, mainly out of Oman with passengers looking to flee Dubai.
AMERICAN STUCK IN MIDDLE EAST ESCAPES IN RACE TO REACH CRITICALLY ILL HUSBAND IN CALIFORNIA
FlightRadar24 shared flights flying in and out of Muscat airport. (@Flightradar24 via X)
“We evacuated some of our own staff who were just visiting the region, and we arranged transport via the Hatta crossing into Oman from the UAE to get them to Muscat from where they flew out of the region,” the spokesperson said. “The border crossing time at Hatta took around 3–4 hours, as of Sunday, but I suspect this has increased now, as more people look at this option.”
Light flight jet trips from Muscat, Oman, to Istanbul, Turkey, are reportedly going for more than $93,000, according to Forbes, which said the price was about double the usual rate.
The outlet added the same route on heavy jets can cost up to $140,000.
AMERICANS IN MORE THAN A DOZEN MIDDLE EAST NATIONS URGED TO FLEE
This map shows the targets of Iran’s retaliatory strikes. (Fox News)
The U.S. and Israel launched attacks on Iran Saturday, triggering retaliatory attacks targeting countries in the region that host U.S. interests.
Mora Namdar, Assistant Secretary of State for Consular Affairs, advised U.S. citizens to leave Bahrain, Egypt, Iran, Iraq, Israel, the West Bank and Gaza, Jordan, Kuwait, Lebanon, Oman, Qatar, Saudi Arabia, Syria, the United Arab Emirates and Yemen.
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The limited number of available aircraft has pushed up prices, as citizens and travelers attempt to flee.
Fox News Digital’s Ryan Morik and Ashley Carnahan contributed to this report.
World
Fact check: Did French border guards mock influencers returning from Dubai amid Iran war?
Social media posts have showed French border guards stationed in airport arrivals with signs that appear to read, “to all the influencers and other people in tax havens such as Dubai, the tax authorities wish you a smooth return to France”. But is this real?
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