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Use of Wegovy and other weight-loss drugs soars among kids and young adults

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Use of Wegovy and other weight-loss drugs soars among kids and young adults

At 17, Israel McKenzie was so burdened by obesity that he stopped going to high school in person and was embarrassed to speak to people at his restaurant job.

“I was in a really dark place,” says McKenzie, whose weight had climbed to 335 pounds on his 6-foot-1 frame, despite repeated efforts to diet and exercise. “I had given up hope.”

But last year, the weight-loss drug Wegovy helped him shed 110 pounds in nine months, making the rural Tennessee teen part of a surge of adolescents and young adults using diabetes and obesity medications known as GLP-1 receptor agonists, new research shows.

Even as millions of older adults clamor for drugs such as Ozempic and Wegovy, monthly use of the medications soared in people aged 12 to 25. That’s according to the new analysis of dispensing records from nearly 94% of U.S. retail pharmacies from 2020 to 2023.

The report, published in the journal JAMA on Wednesday, used the IQVIA prescription database to compile the first look at the national uptake of GLP-1 drugs among that age group. Nearly 31,000 children aged 12 to 17 and more than 162,000 people aged 18 to 25 used the medications in 2023 alone, said Dr. Joyce Lee, a University of Michigan pediatrician and diabetes expert who led the research.

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“What it’s suggesting is that it’s one of the tools in the toolbox and there are more providers prescribing this medication for the population,” she said.

The report shows that the number of 12- to 25-year-olds using any GLP-1 drug — including older medications first approved to treat diabetes in 2005 and for weight loss in 2014 — climbed from about 8,700 a month in 2020 to more than 60,000 a month in 2023, a nearly 600% increase. The rise occurred even as prescriptions of other drugs among those patients fell by about 3%.

Those who received the drugs were just a fraction of young people who struggle with obesity, Lee noted. About 20% of U.S. children and adolescents and about 42% of adults have the chronic disease, according to the U.S. Centers for Disease Control and Prevention.

In early 2023, the American Academy of Pediatrics recommended that children and teens with obesity be evaluated early and treated aggressively, including with surgery and medication if warranted.

McKenzie, the Tennessee teen, said he began gaining weight five years ago, during puberty.

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“I started turning to food for all of my problems,” he said.

The extra weight made his asthma worse and put him in danger of developing diabetes, his doctor said. He tried to follow medical advice by cutting out sugary soda and snack foods and exercising more, but the efforts failed to make a difference.

“My old doctor told me there was nothing he could do,” he said. “He told me it was my fault.”

In early 2023, McKenzie connected with Dr. Joani Jack, a pediatric obesity specialist at Children’s Hospital at Erlanger in Chattanooga, Tennessee, who regularly prescribes GLP-1 drugs for kids.

“I told him I’ve seen 10 other people just like you today and we have lots of tools and treatment options,” Jack said. Those typically include intensive behavioral and nutrition interventions combined with medication, if necessary.

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In McKenzie’s case, Jack prescribed the weight-loss drug Wegovy, which in late 2022 was approved for use in U.S. children over age 12. More than 6,000 kids in that age group received Wegovy in 2023, the new data show. More than 7,600 received Ozempic, which is approved to treat diabetes in adults, but can be used off-label in adolescents. Others received older GLP-1 drugs such as Saxenda and Trulicity.

McKenzie said he had no notable side effects from the medication, but Lee noted that some young people report nausea, vomiting or constipation, including symptoms so serious that they stop the drugs.

It’s important to understand the surging use of these medications in young people, Lee said. The drugs are meant for continuing use, so “we really need to think about the long-term safety and effectiveness of these medications for this population,” she said.

In addition, the drugs are expensive and often difficult to obtain, either because of supply problems or because they’re not covered by insurance.

Notably, government-run Medicaid plans paid for nearly half of the GLP-1 drugs prescribed to 12- to 17-year-olds and about a quarter of those used by people aged 18 to 25, the research found. Commercial insurance covered care for nearly 44% of the younger kids and about two-thirds of those who were older.

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Today, McKenzie says his asthma is better and he looks forward to interacting with co-workers and friends.

“I have a lot of self-confidence now, a lot more than I used to,” he said. “It has changed everything.”

___

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.

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Iran continues firing missiles, drones at neighboring states, with multiple interceptions reported

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Iran continues firing missiles, drones at neighboring states, with multiple interceptions reported

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Iran launched a new wave of attacks on Thursday, with explosions reported in the region and Tehran threatening that the U.S. would “bitterly regret” sinking an Iranian warship.

Iran’s strikes on Thursday targeted Israel, American bases and countries in the region. Israel announced multiple incoming missile attacks as air raid sirens blared in Tel Aviv and Jerusalem.

Azerbaijan’s Ministry of Defense on Thursday said Iran used unmanned aerial vehicles (UAVs) in an attack on Nakhchivan International Airport and other civilian infrastructure. The ministry said the details of the attack and the capabilities of the UAVs were being investigated.

“The Ministry of Defense of the Republic of Azerbaijan strongly condemns the attacks carried out by the armed forces of the Islamic Republic of Iran against civilian infrastructure on the territory of Azerbaijan in the absence of any military necessity. The Islamic Republic of Iran bears the entire responsibility for the incident,” the ministry’s statement read.

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Explosions seen and heard in Azerbaijan as Iran launches retaliatory attacks across the Middle East. (East2West)

Iran has not acknowledged targeting Azerbaijan, despite the country’s ministry of defense pointing the finger at Tehran.

Qatar evacuated residents near the U.S. Embassy in Doha on Thursday, with its Ministry of Defense confirming that the country was “subjected to a missile attack” and that its air defense systems were able to intercept it. The ministry urged the public to remain calm and avoid unofficial information.

Abu Dhabi announced that its authorities were responding to an incident involving falling debris in ICAD 2, which is part of the Industrial City of Abu Dhabi. Six people, identified by Abu Dhabi as Pakistani and Nepali nationals, suffered minor to moderate injuries.

A plume of smoke rises over buildings in Doha, Qatar, on March 5, 2026. (Mahmud Hams/AFP via Getty Images)

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FORMER TOPGUN PILOT DECLARES IRAN MILITARY ‘OVER WITH’ AMID US AIR SUPERIORITY, BUT WARNS OF ANOTHER DANGER

Iran has carried out retaliatory strikes since the launch of Operation Epic Fury, with the latest wave coming one day after the U.S. sunk an Iranian warship, killing at least 87 Iranian sailors. Sri Lankan navy spokesman Cmdr. Buddhika Sampath said 32 people were rescued from the wreck and were admitted to a hospital.

Secretary of War Pete Hegseth defended the move during a news briefing at the Pentagon.

“An American submarine sunk an Iranian warship that thought it was safe in international waters. Instead, it was sunk by a torpedo — Quiet Death. The first sinking of an enemy ship by a torpedo since World War II. Like in that war, back when we were still the War Department, we are fighting to win,” Hegseth said.

Missile interceptions are seen in the sky on March 5, 2026, in Central Israel. (Alexi J. Rosenfeld/Getty Images)

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ISRAEL’S MILITARY RELEASES VIDEO SHOWING OBLITERATION OF IRAN’S MISSILE LAUNCHERS, DEFENSE SYSTEMS

Iranian leaders condemned the attack, with Foreign Minister Abbas Araghchi accusing the U.S. Navy of committing “an atrocity at sea.” Meanwhile, Ayatollah Abdollah Javadi Amoli appeared on state television and called for the shedding of Israeli and “Trump’s blood.”

“Fight the oppressive America, his blood is on my shoulders,” he said in a rare call for violence from an ayatollah, one of the highest ranks within the clergy of Shiite Islam.

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The U.S. and Israel launched the war on Saturday with strikes targeting Iran’s leadership, including the supreme leader, Ayatollah Ali Khamenei, who was killed. Iran’s missile arsenal and nuclear facilities were also hit.

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The Associated Press contributed to this report.

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Which Kurdish groups is the US rallying to fight Iran?

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Which Kurdish groups is the US rallying to fight Iran?

Iran has launched operations targeting Iranian and Iraqi Kurdish groups in the semi-autonomous Kurdish region in neighbouring Iraq as the regional war ignited by the United States and Israel entered its sixth day, with more than 1,000 people killed across the country.

State television, Press TV, reported early on Thursday that Tehran was striking “anti-Iran separatist forces”, referring to Iranian and Iraqi Kurdish groups believed to be based in mountainous, hard-to-reach areas near the Iran-Iraq border.

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Iranian missiles hit Sulaimaniyah city in the semi-autonomous Kurdistan region, according to local reports.

“We targeted the headquarters of Kurdish groups opposed to the revolution in Iraqi Kurdistan with three missiles,” Iran’s official IRNA news agency reported on Thursday, quoting a military statement. The Iranian military said earlier on Tuesday it used “30 drones” on Kurdish positions.

The attack comes just days after multiple publications reported that US President Donald Trump was in active talks with Iranian and Iraqi Kurdish groups, and that Washington hopes to use them to spur a popular uprising.

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Various Iranian Kurdish groups, which share close ties with Iraqi Kurds, have long opposed Tehran from their bases in northern Iraq and along the Iraq-Iran border. These groups reportedly have thousands of fighters between them.

Here’s what we know so far:

People gather near debris from a drone that fell onto a building near Erbil airport, amid the US-Israeli conflict with Iran, in the Ankawa district of Erbil, Iraq, on March 4, 2026 [Khalid al-Mousily/Reuters]

Why are Kurdish groups cooperating with the US?

US officials said the aim is to stretch Iranian forces and take out the remains of the military-dominated Iranian government, according to reporting by CNN.

There is also speculation that the groups could be supported to take control of northern Iran to create a ground buffer for Israeli forces, possibly streaming in from Iraq.

US-Israeli bombings have heavily targeted areas along the Iraq-Iran border since the start of the war on Saturday, possibly to degrade Iranian defences and allow Kurdish opposition groups to cross fully into Iran, according to a briefing by US-based think tank, the Soufan Center.

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The US has not ruled out sending ground forces, although analysts told Al Jazeera Iran’s rugged territory would make that very difficult.

If the US does support these groups against Tehran, it would mean that Washington is treating them like armed “players on a board,” Winthrop Rodgers, associate fellow at the UK think tank, Chatham House, told Al Jazeera.

INTERACTIVE - WHERE ARE THE KURDS - JAN19, 2026 copy-1768814414
(Al Jazeera)

Which Kurdish groups are there?

Neither the US nor Kurdish groups had confirmed any agreements by Thursday.

However, it is known that Trump has spoken to the leaders of two Kurdish groups in Iraq: Masoud Barzani, leader of the Kurdistan Democratic Party, and Bafel Talabani, leader of the Patriotic Union of Kurdistan (PUK), according to US publication, Axios. Talabani confirmed the call on Wednesday.

Trump also spoke to Mustafa Hijri, head of the Democratic Party of Iranian Kurdistan (KDPI), on Tuesday, CNN reported, quoting a Kurdish official.

Meanwhile, Iranian Kurdish rebel groups, which have thousands of fighters along the Iraq-Iran border, formed the Coalition of Political Forces of Iranian Kurdistan (CPFIK) alliance one week before the war broke out.

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The group issued statements at the start of the conflict, signalling imminent intervention and urging Iranian military members to defect. According to Israel’s I24News, thousands of its fighters were in Iran by Wednesday.

Here are the different groups:

Kurdistan Democratic Party: The ruling party in the semi-autonomous Kurdistan Regional Government (KRG). The party controls the capital city of Erbil as well as Duhok. It has historical ties with Iranian Kurdish groups.

However, the KRG is not eager to be seen as supporting attacks on Iran, even as Iranian drones have hit US assets in Erbil. On Wednesday, Kurdistan region President Nechirvan Barzani spoke with Iranian Foreign Minister Abbas Araghchi and told him his region “will not be part of conflicts” targeting Tehran.

In 2023, the two countries signed a security deal that saw Iraq promise to disarm and relocate Iranian opposition groups on its territory, although it appears many groups are still based there, reflecting the limited influence the government wields over them.

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Iraqi Kurds, who have close ties with both the US and Iran, are in a “difficult position”, said Rodgers.

“They are under tremendous pressure from a wide range of forces, including (pro-Iran) Iraqi militias. They will try to stay out of the conflict as much as they can, but that will likely prove impossible,” he said.

Patriotic Union of Kurdistan (PUK): The PUK is the official opposition in the semi-autonomous Kurdistan region and also nationally relevant as Iraqi President Abdul Latif Rashid is a member. In a statement on Sunday, Rashid urged dialogue and an end to the war. Iraq declared three days of mourning following the killing of Iran’s Ayatollah Ali Khamenei in US-Israeli strikes on Tehran on Saturday.

Coalition of Political Forces of Iranian Kurdistan (CPFIK): Formed on February 22, 2026, the group includes six Iranian Kurdish opposition groups seeking an independent state.

Kurdistan Democratic Party of Iran (KDPI) – Based in the Kurdistan region, the group has about 1,200 members and is proscribed as a “terror” group by Iran.

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Kurdistan Freedom Party (PAK) – Also based in Kurdistan, it has an estimated 1,000 members.

Kurdistan Free Life Party (PJAK) – A close ally of the Turkish opposition armed group, Kurdistan Workers’ Party (PKK), PJAK is proscribed as a “terror” group by Ankara. PJAK’s armed wing, the Eastern Kurdistan Units (YRK), is believed to have between 1,000 and 3,000 members, many of them women. It is based in the rugged Qandil Mountains near the Iran-Iraq border and in the semiautonomous Kurdistan region. It has launched numerous attacks on Iranian forces in the past decade. A recent Iranian strike reportedly killed one fighter.

Organisation of Iranian Kurdistan Struggle (Khabat) – It has an unknown number of fighters.

Komala of the Toilers of Kurdistan – Based in Iraq’s KRG, it has an unknown number of fighters.

Komala Party of Iranian Kurdistan (KPIK) – Also headquartered in the Kurdistan region, it has an estimated 1,000 fighters in 2017.

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PAK
A fighter from the Kurdistan Freedom Party (PAK) carries a rifle and gestures while standing on rocky terrain, at a training session at a base near Erbil, Iraq, on February 12, 2026 [File: Thaier Al-Sudani/Reuters]

What is the history of US involvement with Kurdish resistance groups in the Middle East?

Kurds are an ethnic minority spread across the Middle East with a shared language and culture. They do not have a state of their own and have historically been marginalised across countries – mainly Iran, Iraq, Syria and Turkiye.

For decades, several armed Kurdish groups have sought self-governance in Turkiye, Syria and Iran.

In Iraq, Kurdish nationalist groups gained some success during the 1991 Gulf War by working with the US, which helped establish the self-governing Kurdistan region of Iraq. The US Central Intelligence Agency (CIA) also trained and armed its army, known as the Peshmerga, after the US invaded Iraq in 2003. In 2005, the semiautonomous region was officially recognised in Iraq’s constitution.

Since 2017, Washington has also armed and trained the People’s Protection Units (YPG), a Syrian Kurdish militia that Turkiye lists as a “terror” group because of its links with the proscribed PKK. The group, which successfully resisted ISIL (ISIS), now forms the main component of the Syrian Democratic Forces (SDF). It controlled Raqqa and other ISIL strongholds.

However, when it began military clashes with Syrian forces under the President Ahmed al-Sharaa-led government last August, Washington turned away from the group and backed Damascus instead. In January this year, the SDF signed an agreement with the Syrian government to integrate into the government forces. In return, the Syrian government recognised Kurdish rights.

In Turkiye, meanwhile, the PKK, whose presence in northern Iraq has long been a source of tension with Ankara, declared a ceasefire in March 2025, after a call from its imprisoned leader, Abdullah Ocalan, to disarm.

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How does Kurdish resistance in Iran compare with others?

Iranian Kurds opposed the Iranian government even before the formation of the Islamic Republic in 1979, Rodgers said, and Tehran’s current weakness provides an opportunity for them to advance their political aims in the country.

However, the new coalition of multiple diverse groups is unprecedented, the analyst added, and their internal dynamics will be a key decisive factor in what role Kurdish groups will play in this war.

“Support from the US is helpful, especially in terms of targeting security forces’ infrastructure with air strikes, but they will likely be cautious about relying too much on Washington, especially from an administration as capricious and disorganised as Trump’s,” Rodgers said, noting how Washington abandoned the Kurds in Syria.

Unlike the split Iranian movements, Iraqi Kurds have long united to form a devolved government enshrined in the Iraqi constitution, built an advanced economy, and secured substantive relations with a wide range of foreign countries. That’s something Kurdish groups will also be hoping to establish in a democratic Iran, he said.

“I think it is unlikely that the Trump administration has made any commitments to the Iranian Kurds about supporting their political goals,” Rodgers said, adding that the US’s plan “does not look fully thought through at all”.

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Netflix, After Walking Away From Warner Bros. Deal, Will ‘Move Forward’ With ‘$2.8 Billion in Our Pocket That We Didn’t Have a Few Weeks Ago,’ CFO Says

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Netflix, After Walking Away From Warner Bros. Deal, Will ‘Move Forward’ With ‘.8 Billion in Our Pocket That We Didn’t Have a Few Weeks Ago,’ CFO Says

Netflix is no longer contemplating a future that includes Warner Bros., having ceded the heated M&A battle to Paramount Skydance. Netflix CFO Spence Neumann, speaking Wednesday at the Morgan Stanley Technology, Media & Telecom Conference, reiterated the company’s position that it bailed out of the bidding for Warner Bros. because Paramount increased its offer price.

“The short answer is, it was all about price,” Neumann said. “We said all along this opportunity was a nice-to-have at the right price, not a must-have at any price,” he added, echoing Netflix co-CEO Ted Sarandos’ previous statement.

Netflix, when it struck the deal to buy WB’s studios and streaming business in December, was playing “offense, not defense,” Neumann said. According to the CFO, Netflix has a “unique view” into how to value the WBD assets. “We went into it with a point of view on price,” he said. “When it became clear it didn’t make sense for us financially anymore,” the company bowed out.

“Now we move forward, and we move forward with $2.8 billion in our pocket that we didn’t have a few weeks ago,” said Neumann, referring to the breakup fee it received from Paramount Skydance.

On Feb. 26, Netflix abandoned its deal to buy Warner Bros.’s studios and streaming business after David Ellison’s Paramount upped its hostile bid for WBD in its entirety to $31/share — leaving Paramount the winner of a debt-fueled takeover of the media conglomerate. Paramount Skydance paid Netflix the $2.8 billion breakup fee once Warner Bros. Discovery terminated its agreement with Netflix in favor of Paramount’s “superior” offer.

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Asked if the Warner Bros. bidding war changed Netflix’s M&A strategy, Neumann replied, “I know it sounds boring, but it’s really no change.” The company will “continue to stay focused on what are those opportunities” to accelerate the growth of the business, he said.

Neumann said Netflix, by the end of the bidding process for Warner Bros., had “a stronger belief” that “we would have been great stewards” for those assets. And, he insisted, Netflix had high confidence that it had a “clear path” to regulatory approval.

“At the end of the day, we were going to be disciplined” on the price it was willing to pay for Warner Bros., Neumann said.

In 2026, Netflix plans to boost its total cash content spending to around $20 billion, up 10% from last year. It is forecasting revenue of $50.7 billion-$51.7 billion, which would be an increase of 12%-14% year over year, and projects hitting 31.5% operating margin in 2026. The streaming heavyweight reported more than 325 million subscribers worldwide as of the end of 2025, up from 301.2 million a year prior.

The expected 10% increase in Netflix’s content spending this year is in line with its expected revenue growth, Neumann said. “It’s really no change in our approach,” he said. “We really want to be that starting point and destination for professionally produced content for creators around the world.”

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