Science
Too expensive, too slow: NASA asks for help with JPL's Mars Sample Return mission
After months of turmoil over the future of a vaunted mission to bring samples of the Red Planet back to Earth, NASA has its verdict on Mars Sample Return.
The space agency is “committed” to bringing those rocks back from Mars, Administrator Bill Nelson said Monday, but will have to do it with way less money and in far less time than currently designed.
And how exactly is NASA going to pull that off? Right now it has no idea — and it’s looking for someone who does.
“I have asked our folks to reach out with a request for information to industry, to [the Jet Propulsion Laboratory] and to all NASA centers, and to report back this fall an alternate plan that will get [the samples] back quicker and cheaper,” Nelson said in a press conference at NASA headquarters.
His comments came in response to an independent review commissioned by NASA last year that declared there was “near zero probability” of Mars Sample Return making its proposed 2028 launch date, and “no credible” way to fulfill the mission within its current budget.
Pulling off the mission as designed would likely cost up to $11 billion, the review board found, with the samples not reaching Earth until at least 2040.
“The bottom line is that $11 billion is too expensive, and not returning samples until 2040 is unacceptably too long,” Nelson said. “It’s the decade of the 2040s that we’re going to be landing astronauts on Mars.”
The announcement comes as something of a blow to JPL, the La Cañada Flintridge institution tasked with managing the mission. JPL has already laid off more than 600 employees and 40 contractors this year after NASA ordered it to reduce spending in anticipation of budget cuts spurred by the challenges of Mars Sample Return.
Proposals go out soon to all NASA centers and the private aerospace sector for “a revised plan that utilizes innovation and proven technology to lower risks, to lower costs and to lower mission complexity so we can return these really precious samples to Earth in the 2030s,” said Nicky Fox, associate administrator, Science Mission Directorate. The due date for proposals is next month, and those selected for further study will get NASA grants this summer.
This essentially puts JPL in a position of having to compete for its own project.
“Right now if JPL were to come up with the answer, then I’d say JPL is gonna be sitting pretty good,” Nelson said during Monday’s news conference. “But we’re opening this up to everyone because we want to get every new and fresh idea that we can.”
NASA’s decision to outsource a solution to the Mars Sample Return problem frustrated some Mars scientists.
“What I expected is for NASA to step up and say, ‘These things are hard and we choose to do them,’ ” said Bethany L. Ehlmann, a planetary scientist at Caltech. “That is the leadership required to be the nation leading the world in space exploration.”
A joint project with the European Space Agency, Mars Sample Return would deliver rocks, rubble and dust that have already been gathered and sealed into tubes by the Perseverance rover.
The current design relies on a lander that would retrieve those tubes from the Red Planet’s Jezero Crater and use a small rocket to ferry them into Martian orbit, where they would rendezvous with a spacecraft that would make the journey back to Earth. The rocket would touch down on Earth roughly five years after the orbiter’s launch.
The ultimate goal is to comb the samples for evidence that life has ever existed on Mars, and to help NASA plan for future crewed missions, Nelson said.
In the most recent planetary science decadal survey, a report prepared for NASA every 10 years by the National Academy of Sciences, Engineering, and Medicine, planetary scientists named the Mars Sample Return mission as the “highest scientific priority of NASA’s robotic exploration efforts this decade” and argued that the program should be completed “as soon as is practicably possible with no increase or decrease in its current scope.”
But the authors cautioned that the ambitious mission shouldn’t come at the cost of other planetary science, suggesting a roughly $5-billion to $7-billion cap.
“Mars Sample Return is of fundamental strategic importance to NASA, U.S. leadership in planetary science, and international cooperation and should be completed as rapidly as possible,” the report stated. “However, its cost should not be allowed to undermine the long-term programmatic balance of the planetary portfolio.”
The agency is committing to keeping the mission within that recommended budget, Nelson said. Allowing Mars Sample Return’s costs to reach the $8 billion to $11 billion the review board estimated would require NASA “to cannibalize other programs, other science programs, and there are so many that are absolutely important,” Nelson said.
Science
What’s in a Name? For These Snails, Legal Protection
The sun had barely risen over the Pacific Ocean when a small motorboat carrying a team of Indigenous artisans and Mexican biologists dropped anchor in a rocky cove near Bahías de Huatulco.
Mauro Habacuc Avendaño Luis, one of the craftsmen, was the first to wade to shore. With an agility belying his age, he struck out over the boulders exposed by low tide. Crouching on a slippery ledge pounded by surf, he reached inside a crevice between two rocks. There, lodged among the urchins, was a snail with a knobby gray shell the size of a walnut. The sight might not dazzle tourists who travel here to see humpback whales, but for Mr. Avendaño, 85, these drab little mollusks represent a way of life.
Marine snails in the genus Plicopurpura are sacred to the Mixtec people of Pinotepa de Don Luis, a small town in southwestern Oaxaca. Men like Mr. Avendaño have been sustainably “milking” them for radiant purple dye for at least 1,500 years. The color suffuses Mixtec textiles and spiritual beliefs. Called tixinda, it symbolizes fertility and death, as well as mythic ties between lunar cycles, women and the sea.
The future of these traditions — and the fate of the snails — are uncertain. The mollusks are subject to intense poaching pressure despite federal protections intended to protect them. Fishermen break them (and the other mollusks they eat) open and sell the meat to local restaurants. Tourists who comb the beaches pluck snails off the rocks and toss them aside.
A severe earthquake in 2020 thrust formerly submerged parts of their habitat above sea level, fatally tossing other mollusks in the snail’s food web to the air, and making once inaccessible places more available to poachers.
Decades ago, dense clusters of snails the size of doorknobs were easy to find, according to Mr. Avendaño. “Full of snails,” he said, sweeping a calloused, violet-stained hand across the coves. Now, most of the snails he finds are small, just over an inch, and yield only a few milliliters of dye.
Science
Video: This Parrot Has No Beak, But Is at the Top of the Pecking Order
new video loaded: This Parrot Has No Beak, But Is at the Top of the Pecking Order
By Meg Felling and Carl Zimmer
April 20, 2026
Science
Contributor: Focus on the real causes of the shortage in hormone treatments
For months now, menopausal women across the U.S. have been unable to fill prescriptions for the estradiol patch, a long-established and safe hormone treatment. The news media has whipped up a frenzy over this scarcity, warning of a long-lasting nationwide shortage. The problem is real — but the explanations in the media coverage miss the mark. Real solutions depend on an accurate understanding of the causes.
Reporters, pharmaceutical companies and even some doctors have blamed women for causing the shortage, saying they were inspired by a “menopause moment” that has driven unprecedented demand. Such framing does a dangerous disservice to essential health advocacy.
In this narrative, there has been unprecedented demand, and it is explained in part by the Food and Drug Administration’s recent removal of the “black-box warning” from estradiol patches’ packaging. That inaccurate (and, quite frankly, terrifying) label had been required since a 2002 announcement overstated the link between certain menopause hormone treatments and breast cancer. Right-sizing and rewording the warning was long overdue. But the trouble with this narrative is that even after the black-box warning was removed, there has not been unprecedented demand.
Around 40% of menopausal women were prescribed hormone treatments in some form before the 2002 announcement. Use plummeted in its aftermath, dipping to less than 5% in 2020 and just 1.8% in 2024. According to the most recent data, the number has now settled back at the 5% mark. Unprecedented? Hardly. Modest at best.
Nor is estradiol a new or complex drug; the patch formulation has existed for decades, and generic versions are widely manufactured. There is no exotic ingredient, no rare supply chain dependency, no fluke that explains why women are suddenly being told their pharmacy is out of stock month after month.
The story is far more an indictment of the broken insurance industry: market concentration, perverse incentives and the consequences of allowing insurance companies to own the pharmacy benefit managers that effectively control drug access for the majority of users. Three companies — CVS Caremark, Express Scripts and OptumRx — manage 79% of all prescription drug claims in the United States. Those companies are wholly owned subsidiaries of three insurance behemoths: CVS Health, Cigna and UnitedHealth Group, respectively. This means that the same corporation that sells you your insurance plan also decides which drugs get covered, at what price, and whether your pharmacy can stock them. This is called vertical integration. In another era, we might have called it a cartel. The resulting problems are not unique to hormone treatments; they have affected widely used medications including blood thinners, inhalers and antibiotics. When a low-cost generic such as estradiol — a medication with no blockbuster profit margins and no patent protection — runs into friction in this system, the friction is not random. It is structural. Every decision in that chain is filtered through the same corporate profit motive. And when the drug in question is an off-patent estradiol patch that has negligible profit margins because of generic competition but requires logistical investment to keep consistently in stock? The math on “how much does this company care about ensuring access” is not complicated.
Unfortunately, there is little financial incentive to ensure smooth, consistent access. There is, however, significant financial incentive to steer patients toward branded alternatives, or simply to let supply tighten — because the companies aren’t losing much profit if sales of that product dwindle. This is not a conspiracy theory: The Federal Trade Commission noted this dynamic in a report that documented how pharmacy benefit managers’ practices inflate costs, reduce competition and harm patient access, particularly for independent pharmacies and for generic drugs.
Any claim that the estradiol patch shortage is meaningfully caused by more women now demanding hormone treatments is a distraction. It is also misogyny, pure and simple, to imply that the solution to the shortage is for women’s health advocates to dial it down and for women to temper their expectations. The scarcity of estradiol patches is the outcome of a broken system refusing to provide adequate supply.
Meanwhile, there are a few strategies to cope.
- Ask your prescriber about alternatives. Estradiol is available in multiple formulations, including gel, spray, cream, oral tablet, vaginal ring and weekly transdermal patch, which is a different product from the twice-weekly patch and may be more consistently available depending on manufacturer and region.
- Consider an online pharmacy. Many are doing a good job locating and filling these prescriptions from outside the pharmacy benefit manager system.
- Call ahead. Patch shortages are inconsistent across regions and distributors. A call to pharmacies in your area, or a broader geographic radius if you’re able, can locate stock that your regular pharmacy doesn’t have.
- Consider a compounding pharmacy. These sources can sometimes meet needs when commercially manufactured products are inaccessible. The hormones used are the same FDA-regulated bulk ingredients.
Beyond those Band-Aid solutions, more Americans need to fight for systemic change. The FTC report exists because Congress asked for it and committed to legislation that will address at least some of the problems. The FDA took action to change the labeling on estrogen in the face of citizen and medical experts’ pressure; it should do more now to demand transparency from patch manufacturers.
Most importantly, it is on all of us to call out the cracks in the current system. Instead of repeating “there’s a patch shortage” or a “surge in demand,” say that a shockingly small minority of menopausal women still even get hormonal treatments prescribed at all, and three drug companies control the vast majority of claims in this country. Those are the real problems that need real solutions.
Jennifer Weiss-Wolf, the executive director of the Birnbaum Women’s Leadership Center at New York University School of Law, is the author of the forthcoming book “When in Menopause: A User’s Manual & Citizen’s Guide.” Suzanne Gilberg, an obstetrician and gynecologist in Los Angeles, is the author of “Menopause Bootcamp.”
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