Science
How Foreign Aid Cuts Are Setting the Stage for Disease Outbreaks
Dangerous pathogens left unsecured at labs across Africa. Halted inspections for mpox, Ebola and other infections at airports and other checkpoints. Millions of unscreened animals shipped across borders.
The Trump administration’s pause on foreign aid has hobbled programs that prevent and snuff out outbreaks around the world, scientists say, leaving people everywhere more vulnerable to dangerous pathogens.
That includes Americans. Outbreaks that begin overseas can travel quickly: The coronavirus may have first appeared in China, for example, but it soon appeared everywhere, including the United States. When polio or dengue appears in this country, cases are usually linked to international travel.
“It’s actually in the interest of American people to keep diseases down,” said Dr. Githinji Gitahi, who heads Amref Health Africa, a large nonprofit that relies on the United States for about 25 percent of its funding.
“Diseases make their way to the U.S. even when we have our best people on it, and now we are not putting our best people on it,” he added.
In interviews, more than 30 current and former officials of the United States Agency for International Development, members of health organizations and experts in infectious diseases described a world made more perilous than it was just a few weeks ago.
Many spoke on condition of anonymity for fear of retaliation by the federal government.
The timing is dire: The Democratic Republic of Congo is experiencing the deadliest mpox outbreak in history, with cases exploding in a dozen other African countries.
The United States is home to a worsening bird flu crisis. Multiple hemorrhagic fever viruses are smoldering: Ebola in Uganda, Marburg in Tanzania, and Lassa in Nigeria and Sierra Leone.
In 2023, U.S.A.I.D. invested about $900 million to fund labs and emergency-response preparedness in more than 30 countries. The pause on foreign aid froze those programs. Even payments to grantees for work already completed are being sorted out in the courts.
Waivers issued by the State Department were intended to allow some work to continue on containing Ebola, Marburg and mpox, as well as preparedness for bird flu.
But Trump administration appointees choked payment systems and created obstacles to implementing the waivers, according to a U.S.A.I.D. memo by Nicholas Enrich, who was the agency’s acting assistant administrator for global health until Sunday.
Then last month, the Trump administration canceled about 5,800 contracts, effectively shuttering most U.S.A.I.D.-funded initiatives, including many that had received permission to continue.
“It was finally clear that we were not going to be implementing” even programs that had waivers, Mr. Enrich recalled in an interview.
The decision is likely to result in more than 28,000 new cases of infectious diseases like Ebola and Marburg, and 200,000 cases of paralytic polio each year, according to one estimate.
Secretary of State Marco Rubio “has been working diligently since being sworn in to review every dollar spent,” the State Department said in an emailed statement.
“We’ll be able to say that every program that we are out there operating serves the national interest, because it makes us safer or stronger or more prosperous,’” the statement quoted Mr. Rubio as saying.
Most U.S.A.I.D. staff members were terminated or placed on administrative leave without warning. The agency had more than 50 people dedicated to outbreak responses, the result of a Congressional push to beef up pandemic preparedness.
Now it has six. Those who were fired included the organization’s leading expert in lab diagnostics and the manager of the Ebola response. “I have no idea how six people are going to run four outbreak responses,” said one official who was let go.
Also sent home were hundreds of thousands of community health workers in Africa who were sentinels for diseases.
In early January, the Tanzanian government denied there were new cases of Marburg, a hemorrhagic fever. It was a community health worker trained through a U.S.-funded Ebola program who reported the disease a week later.
The outbreak eventually grew to include 10 cases; it is now under control, the government has said.
Even in quieter times, foreign aid helps to prevent, detect and treat diseases that can endanger Americans, including drug-resistant H.I.V., tuberculosis and malaria, and bacteria that don’t respond to available antibiotics.
Much of that work has stopped, and other organizations or countries cannot fill the gap. Compounding the loss is America’s withdrawal from the World Health Organization, which has instituted cost-cutting measures of its own.
“This is a lose-lose scenario,” said Dr. Keiji Fukuda, who has led pandemic prevention efforts at the W.H.O. and the C.D.C.
The slashing of foreign aid deprives the world of American leadership and expertise, but it also locks the United States out of global discussions, Dr. Fukuda said: “For the life of me, I cannot see the justification or the reason for this very calculated, systematic approach to pull down public health.”
Trying to Adapt
U.S.A.I.D.’s intense focus on global health security is barely a decade old, but it has mostly received bipartisan support. The first Trump administration expanded the program to 50 countries.
Much of the aid was intended to help them eventually tackle problems on their own. And to some extent, that was happening.
But confronted with a new virus or outbreak, “there’s so many things that one has to do and learn, and many countries can’t do that on their own,” said Dr. Lucille Blumberg, an infectious diseases physician and expert on emerging diseases.
U.S.A.I.D. and its partners helped countries identify the expertise, training and machinery they needed, brought together officials in various ministries and engaged farmers, businesses and families.
“It actually doesn’t cost the U.S. government that much,” said an official with a large development organization. “But that sort of trust-building, communication, sharing evidence is a real strength that the U.S. brings to health security — and that’s gone.”
In Africa, some countries have reacted to the disappearance of aid with alarm, others with resignation. “We’re doing our best to adapt to this development,” said Dr. Muhammad Ali Pate, Nigeria’s health minister.
“The U.S. government is not responsible, ultimately, for the health and the security of Nigerian people,” he said. “At the end of the day, the responsibility is ours.”
A successful outbreak response requires coordination of myriad elements: investigators to confirm the initial report; workers trained to do testing; access to test kits; transport of samples; a lab with enough workers, running water, electricity and chemical supplies for diagnoses; and experts to interpret and act on the results.
In broad strokes, the C.D.C. provided expertise on diseases, U.S.A.I.D. funded logistics and the W.H.O. convened stakeholders, including ministries of health.
Before the aid freeze, employees from each organization often talked every day, sharing information and debating strategy. Together, they lowered response time to an outbreak from two weeks in 2014 to five days in 2022 to just 48 hours most recently.
But now, C.D.C. experts who have honed their expertise over decades are not even allowed to speak to colleagues at the W.H.O.
U.S.A.I.D. funding for sample transport, lab supplies, fuel for generators and phone plans for contact tracers has ended. Much of its investment in simple solutions to seemingly intractable problems has also stopped.
In West Africa, for example, rodents that spread Lassa fever invade homes in search of food. One program in U.S.A.I.D.’s Stop Spillover project introduced rodent-proof food containers to limit the problem, but has now shut down.
In Congo, where corruption, conflict and endless outbreaks mean that surveillance “looks like Swiss cheese even at the best of times,” the mpox response slowed because there were no health workers to transport samples, said a U.S.A.I.D. official familiar with the response.
More than 400 mpox patients were left stranded after fleeing overwhelmed clinics. Before a waiver restarted some work, the United States identified two new cases of mpox, both in people who had traveled to East Africa.
In Kenya, U.S.A.I.D. supported eight labs and community-based surveillance in 12 high-risk counties. Labs in the Marsabit, Mandera and Garissa counties — which border Ethiopia and Somalia — have run out of test kits and reagents for diseases including Rift Valley fever, yellow fever and polio, and have lost nearly half their staff.
Kenya also borders Uganda and Tanzania and is close to Congo — all battling dangerous outbreaks — and has lost more than 35,000 workers.
“These stop-work orders would mean that it increases the risk of an index case passing through unnoticed,” Dr. Gitahi said, referring to the first known case in an outbreak. His organization has terminated nearly 400 of its staff of 2,400.
Many labs in Africa store samples of pathogens that naturally occur in the environment, including several that can be weaponized. With surveillance programs shut off, the pathogens could be stolen, and a bioterrorism attack might go undetected until it was too late to counter.
Some experts worried about bad actors who may release a threat like cholera into the water, or weaponize anthrax or brucellosis, common in African animals. Others said they were concerned that even unskilled handling of these disease threats might be enough to set off a disaster.
Funding from the U.S. government helped hire and train lab workers to maintain and dispose of dangerous viruses and bacteria safely.
But now, pathogens can be moved in and out of labs with no one the wiser. “We have lost our ability to understand where pathogens are being held,” said Kaitlin Sandhaus, founder and chief executive of Global Implementation Solutions.
Her company helped 17 African labs become accredited in biosafety procedures and supported five countries in drafting laws to ensure compliance. Now the firm is shutting down.
In the future, other countries, including China, will know more about where risky pathogens are housed, Ms. Sandhaus said: “It feels very dangerous to me.”
China has already invested in building labs in Africa, where it is cheaper and easier to “work on whatever you would like without anyone else paying attention,” said one U.S.A.I.D. official.
Russia, too, is providing mobile labs to Ugandans in Mbale, on the border with Kenya, another official said.
Some African countries like Somalia have fragile health systems and persistent security threats, yet minimal capacity for tracking infections that sicken animals and people, said Abdinasir Yusuf Osman, a veterinary epidemiologist and chair of a working group in Somalia’s health ministry.
Each year Somalia exports millions of camels, cattle and other livestock, primarily to the Middle East. The nation has relied heavily on foreign aid to screen the animals for diseases, he said.
“The consequences of this funding shortfall, in my view, will be catastrophic and increase the likelihood of uncontrolled outbreaks,” Dr. Osman said.
In countries with larger economies, foreign aid has helped build relationships. Thailand is a pioneer in infectious diseases, and U.S.A.I.D. was funding a modest project on malaria elimination that boosts its surveillance capabilities.
The abrupt end to that commitment risks losing good will, said Jui Shah, who helped run the program.
“In Asia, relationships are crucial for any type of work, but especially for roles that work with surveillance and patient data,” she said. “Americans will suffer if other countries hesitate to engage with us about outbreaks.”
Science
Judge blocks Trump administration move to cut $600 million in HIV funding from states
A federal judge on Thursday blocked a Trump administration order slashing $600 million in federal grant funding for HIV programs in California and three other states, finding merit in the states’ argument that the move was politically motivated by disagreements over unrelated state sanctuary policies.
U.S. District Judge Manish Shah, an Obama appointee in Illinois, found that California, Colorado, Illinois and Minnesota were likely to succeed in arguing that President Trump and other administration officials targeted the U.S. Centers for Disease Control and Prevention funding for termination “based on arbitrary, capricious, or unconstitutional rationales.”
Namely, Shah wrote that while Trump administration officials said the programs were cut for breaking with CDC priorities, other “recent statements” by officials “plausibly suggest that the reason for the direction is hostility to what the federal government calls ‘sanctuary jurisdictions’ or ‘sanctuary cities.’”
Shah found that the states had shown they would “suffer irreparable harm” from the cuts, and that the public interest would not be harmed by temporarily halting them — and as a result granted the states a temporary restraining order halting the administration’s action for 14 days while the litigation continues.
Shah wrote that while he may not have jurisdiction to block a simple grant termination, he did have jurisdiction to halt an administration directive to terminate funding based on unconstitutional grounds.
“More factual development is necessary and it may be that the only government action at issue is termination of grants for which I have no jurisdiction to review,” Shah wrote. “But as discussed, plaintiffs have made a sufficient showing that defendants issued internal guidance to terminate public-health grants for unlawful reasons; that guidance is enjoined as the parties develop a record.”
The cuts targeted a slate of programs aimed at tracking and curtailing HIV and other disease outbreaks, including one of California’s main early-warning systems for HIV outbreaks, state and local officials said. Some were oriented toward serving the LGBTQ+ community. California Atty. Gen. Rob Bonta’s office said California faced “the largest share” of the cuts.
The White House said the cuts were to programs that “promote DEI and radical gender ideology,” while federal health officials said the programs in question did not reflect the CDC’s “priorities.”
Bonta cheered Shah’s order in a statement, saying he and his fellow attorneys general who sued are “confident that the facts and the law favor a permanent block of these reckless and illegal funding cuts.”
Science
Contributor: Is there a duty to save wild animals from natural suffering?
The internet occasionally erupts in horror at disturbing images of wildlife: deer with freakish black bubbles all over their faces and bodies, sore-ridden squirrels, horn-growing rabbits.
As a society, we tend to hold romanticized notions about life in the wild. We picture these rabbits nuzzling with their babies, these squirrels munching on some nuts and these deer frolicking through sunlit meadows. Yet the trend of Frankenstein creatures afflicted with various diseases is steadily peeling back this idyllic veneer, revealing the harsher realities that underpin the natural world. And we should do something about it.
First, consider that wild animals — the many trillions of them — aren’t so different from other animals we care about — like dogs and cats — or even from us. They love. They build complex social structures. They have emotions. And most important, they too experience suffering.
Many wild animals are suffering because of us. We destroy their habitats, they’re sterilized and killed by our pollution, and sometimes we hunt them down as trophies. Suffering created by humans is especially galling.
But even in the absence of human impact, wild animals still experience a great deal of pain. They starve and thirst. They get infected by parasites and diseases. They’re ripped apart by other animals. Some of us have bought into the naturalistic fallacy that interfering with nature is wrong. But suffering is suffering wherever it occurs, and we should do something about it when we can. If we have the opportunity to rescue an injured or ill animal, why wouldn’t we? If we can alleviate a being’s suffering, shouldn’t we?
If we accept that we do have an obligation to help wild animals, where should we start? Of course, if we have an obvious opportunity to help an animal, like a bird with a broken wing, we ought to step in, maybe take it to a wildlife rescue center if there are any nearby. We can use fewer toxic products and reduce our overall waste to minimize harmful pollution, keep fresh water outside on hot summer days, reduce our carbon footprint to prevent climate-change-induced fires, build shelter for wildlife such as bats and bees, and more. Even something as simple as cleaning bird feeders can help reduce rates of disease in wild animals.
And when we do interfere in nature in ways that affect wild animals, we should do so compassionately. For example, in my hometown of Staten Island, in an effort to combat the overpopulation of deer (due to their negative impact on humans), officials deployed a mass vasectomy program, rather than culling. And it worked. Why wouldn’t we opt for a strategy that doesn’t require us to put hundreds of innocent animals to death?
But nature is indifferent to suffering, and even if we do these worthy things, trillions will still suffer because the scale of the problem is so large — literally worldwide. It’s worth looking into the high-level changes we can make to reduce animal suffering. Perhaps we can invest in the development and dissemination of cell-cultivated meat — meat made from cells rather than slaughtered animals — to reduce the amount of predation in the wild. Gene-drive technology might be able to make wildlife less likely to spread diseases such as the one afflicting the rabbits, or malaria. More research is needed to understand the world around us and our effect on it, but the most ethical thing to do is to work toward helping wild animals in a systemic way.
The Franken-animals that go viral online may have captured our attention because they look like something from hell, but their story is a reminder that the suffering of wild animals is real — and it is everywhere. These diseases are just a few of the countless causes of pain in the lives of trillions of sentient beings, many of which we could help alleviate if we chose to. Helping wild animals is not only a moral opportunity, it is a responsibility, and it starts with seeing their suffering as something we can — and must — address.
Brian Kateman is co-founder of the Reducetarian Foundation, a nonprofit organization dedicated to reducing consumption of animal products. His latest book and documentary is “Meat Me Halfway.”
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Perspectives
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Ideas expressed in the piece
- Wild animals experience genuine suffering comparable to that of domesticated animals and humans, including through starvation, disease, parasitism, and predation, and society romanticizes wildlife in ways that obscure these harsh realities[1][2]
- Humans have a moral obligation to address wild animal suffering wherever possible, as suffering is morally significant regardless of whether it occurs naturally or results from human action[2]
- Direct intervention in individual cases is warranted, such as rescuing injured animals or providing fresh water during heat waves, alongside broader systemic approaches like reducing pollution and carbon emissions[2]
- Humane wildlife management strategies should be prioritized over lethal approaches when addressing human-wildlife conflicts, as demonstrated by vasectomy programs that manage overpopulation without mass culling[2]
- Large-scale technological solutions, including cell-cultivated meat to reduce predation and gene-drive technology to control disease transmission, should be pursued and researched to systematically reduce wild animal suffering at scale[2]
- The naturalistic fallacy—the belief that natural processes should never be interfered with—is fundamentally flawed when weighed against the moral imperative to alleviate suffering[2]
Different views on the topic
The search results provided do not contain explicit opposing viewpoints to the author’s argument regarding a moral duty to intervene in wild animal suffering. The available sources focus primarily on the author’s work on reducing farmed animal consumption through reducetarianism and factory farming advocacy[1][3][4], rather than perspectives that directly challenge the premise that humans should work to alleviate wild animal suffering through technological or ecological intervention.
Science
Contributor: Factory farming of fish is brewing pathogens
The federal government recently released new dietary guidelines aimed at “ending the war on protein” and steering Americans toward “real foods” — those with few ingredients and no additives. Seafood plays a starring role. But the fish that health advocates envision appearing on our plates probably won’t be caught in the crystal blue waters we’d like to imagine.
Over the past few decades, the seafood industry has completely revolutionized how it feeds the world. As many wild fish populations have plummeted, hunted to oblivion by commercial fleets, fish farming has become all the rage, and captive-breeding facilities have continually expanded to satiate humanity’s ravenous appetite. Today, the aquaculture sector is a $300-billion juggernaut, accounting for nearly 60% of aquatic animal products used for direct human consumption.
Proponents of aquaculture argue that it helps feed a growing human population, reduces pressure on wild fish populations, lowers costs for consumers and creates new jobs on land. Much of that may be correct. But there is a hidden crisis brewing beneath the surface: Many aquaculture facilities are breeding grounds for pathogens. They’re also a blind spot for public health authorities.
On dry land, factory farming of cows, pigs and chickens is widely reviled, and for good reason: The unsanitary and inhumane conditions inside these facilities contribute to outbreaks of disease, including some that can leap from animals to humans. In many countries, aquaculture facilities aren’t all that different. Most are situated in marine and coastal areas, where fish can be exposed to a sinister brew of human sewage, industrial waste and agricultural runoff. Fish are kept in close quarters — imagine hundreds of adult salmon stuffed into a backyard swimming pool — and inbreeding compromises immune strength. Thus, when one fish invariably falls ill, pathogens spread far and wide throughout the brood — and potentially to people.
Right now, there are only a handful of known pathogens — mostly bacteria, rather than viruses — that can jump from aquatic species to humans. Every year, these pathogens contribute to the 260,000 illnesses in the United States from contaminated fish; fortunately, these fish-borne illnesses aren’t particularly transmissible between people. It’s far more likely that the next pandemic will come from a bat or chicken than a rainbow trout. But that doesn’t put me at ease. The ocean is a vast, poorly understood and largely unmonitored reservoir of microbial species, most of which remain unknown to science. In the last 15 years, infectious diseases — including ones that we’ve known about for decades such as Ebola and Zika — have routinely caught humanity by surprise. We shouldn’t write off the risks of marine microbes too quickly.
My most immediate concern, the one that really makes me sweat, is the emergence of drug-resistant bacteria among farmed fish. Aquaculturists are well aware that their fish often live in a festering cesspool, and so many growers will mix antibiotics — including ones that the World Health Organization considers medically important for people — into fish feed, or dump them straight into water, to avoid the consequences of crowded conditions and prevent rampant illness. It would be more appropriate to use antibiotics in animals only when they are sick.
Because of this overuse for prevention purposes, more antibiotics are used in seafood raised by aquaculture than are used in humans or for other farmed animals per kilogram. Many of these molecules will end up settling in the water or nearby sediment, where they can linger for weeks. In turn, the 1 million individual bacteria found in every drop of seawater will be put to the evolutionary test, and the most antibiotic-resistant will endure.
Numerous researchers have found that drug-resistant strains of bacteria are alarmingly common in the water surrounding aquaculture facilities. In one study, evidence of antibiotic resistance was found in over 80% of species of bacteria isolated from shrimp sold in multiple countries by multiple brands.
Many drug-resistant strains in aquatic animals won’t be capable of infecting humans, but their genes still pose a threat through a process known as horizontal transfer. Bacteria are genetic hoarders. They collect DNA from their environment and store it away in their own genome. Sometimes, they’ll participate in swap meets, trading genes with other bacteria to expand their collections. Beginning in 1991, for example, a wave of cholera infected nearly a million people across Latin America, exacerbated by a strain that may have picked up drug-resistant adaptations while circulating through shrimp farms in Ecuador.
Today, drug-resistant bacteria kill over a million people every year, more than HIV/AIDS. I’ve seen this with my own eyes as a practicing tuberculosis doctor. I am deeply fearful of a future in which the global supply of fish — a major protein source for billions of people — also becomes a source of untreatable salmonella, campylobacter and vibrio. We need safer seafood, and the solutions are already at our fingertips.
Governments need to lead by cracking down on indiscriminate antibiotic use. It is estimated that 70% of all antibiotics used globally are given to farm animals, and usage could increase by nearly 30% over the next 15 years. Regulation to promote prudent use of antibiotics in animals, however, has proven effective in Europe, and sales of veterinary antibiotics decreased by more than 50% across 25 European countries from 2011 to 2022. In the United States, the use of medically important antibiotics in food animals — including aquatic ones — is already tightly regulated. Most seafood eaten in the U.S., however, is imported and therefore beyond the reach of these rules. Indeed, antibiotic-resistance genes have already been identified in seafood imported into the United States. Addressing this threat should be an area of shared interest between traditional public health voices and the “Make America Healthy Again” movement, which has expressed serious concerns about the health effects of toxins.
Public health institutions also need to build stronger surveillance infrastructure — for both disease and antibiotic use — in potential hotspots. Surveillance is the backbone of public health, because good decision-making is impossible without good data. Unfortunately, many countries — including resource-rich countries — don’t robustly track outbreaks of antibiotic-resistant pathogens in farmed animals, nor do they share data on antibiotic use in farmed animals. By developing early warning systems for detecting antibiotic resistance in aquatic environments, rapid response efforts involving ecologists, veterinarians and epidemiologists can be mobilized as threats arise to avert public health disasters.
Meanwhile, the aquaculture industry should continue to innovate. Genetic technologies and new vaccines can help prevent rampant infections, while also improving growth efficiency that could allow for more humane conditions.
For consumers, the best way to stay healthy is simple: Seek out antibiotic-free seafood at the supermarket, and cook your fish (sorry, sushi lovers).
There’s no doubt that aquaculture is critical for feeding a hungry planet. But it must be done responsibly.
Neil M. Vora is a practicing physician and the executive director of the Preventing Pandemics at the Source Coalition.
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